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Current Biology, ISSN 0960-9822, 07/2009, Volume 19, Issue 14, pp. R540 - R541
Journal Article
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 2, p. 397
The pyruvate kinase M2 isoform (PKM2) is expressed in cancer and plays a role in regulating anabolic metabolism. To determine whether PKM2 is required for... 
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2015, Volume 60, Issue 4, pp. 514 - 523
Otto Warburg discovered that cancer cells exhibit a high rate of glycolysis in the presence of ample oxygen, a process termed aerobic glycolysis, in 1924... 
BREAST-CANCER | MITOCHONDRIAL PYRUVATE CARRIER | GLUCOSE-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC-CANCER | GROWTH | ALPHA-KETOGLUTARATE | RAS-TRANSFORMED CELLS | TUMOR-CELLS | REDUCTIVE CARBOXYLATION | GLUTAMINE-METABOLISM | CELL BIOLOGY | Neoplasms - metabolism | Glycolysis | Animals | Energy Metabolism | Humans | Oxygen - metabolism | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. SY12-01 - SY12-01
In general cancer cells produce higher levels of reactive oxygen species (ROS) than normal cells due to increased rates of metabolism and defective... 
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4190 - 11
Methylenetetrahydrofolate reductase (MTHFR) catalyzes the irreversible conversion of 5,10-methylene-tetrahydrofolate (THF) to 5-methyl-THF, thereby committing... 
SPECIFICITY | MULTIDISCIPLINARY SCIENCES | Plasma | CRISPR | Tetrahydrofolic acid | Phosphorylation | Allosteric properties | Adenosylmethionine | Cell lines | Methionine | Methylenetetrahydrofolate reductase | Homocysteine | S-Adenosylmethionine | Folic acid
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 07/2015, Volume 14, Issue 7 Supplement, pp. IA01 - IA01
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 02/2019, Volume 216, Issue 2, pp. 253 - 266
Folate metabolism is crucial for many biochemical processes, including purine and thymidine monophosphate (dTMP) biosynthesis, mitochondrial protein... 
MEDICINE, RESEARCH & EXPERIMENTAL | SERINE BIOSYNTHESIS | GAMMA-GLUTAMATE SYNTHETASE | ESCHERICHIA-COLI | NUTRITIONAL SCIENCE | BINDING-PROTEIN | NEURAL-TUBE | MITOCHONDRIAL C-1-TETRAHYDROFOLATE SYNTHASE | IMMUNOLOGY | FOLIC-ACID | MAMMALIAN-CELLS | ONE-CARBON METABOLISM | 321 | Reviews
Journal Article
Cell Metabolism, ISSN 1550-4131, 07/2018, Volume 28, Issue 1, pp. 3 - 4
Glycolysis is prudently regulated and coupled to cell growth. Phosphofructokinase 2 controls glycolytic flux by generating fructose 2,6-bisphosphate, an... 
ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Glycolysis | Phosphofructokinase-1 | Cell Proliferation | Breast Neoplasms | Phosphofructokinase-2 | Humans | Glucose metabolism | Gene expression | Fructose | Cancer
Journal Article