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Blood, ISSN 0006-4971, 07/2017, Volume 130, Issue 3, pp. 236 - 237
In this issue of Blood, Draper et al demonstrate that 2 isoforms of the transcription factor RUNX1, which are generated by alternate promoter usage, play... 
ADULT HEMATOPOIESIS | GENE | STEM-CELL | FLI-1 | DIFFERENTIATION | HEMATOLOGY | EXPRESSION | Index Medicus | Abridged Index Medicus
Journal Article
Science, ISSN 0036-8075, 12/2008, Volume 322, Issue 5909, pp. 1839 - 1842
Differences in the amount of fetal hemoglobin (HbF) that persists into adulthood affect the severity of sickle cell disease and the ?-thalassemia syndromes.... 
Protein isoforms | K562 cells | Erythroblasts | Genes | Cell lines | Small interfering RNA | Genetic loci | Reports | Erythroid cells | Gene expression | Hemoglobins | LOCUS-CONTROL REGION | COMPLEX | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | ZINC-FINGER PROTEIN | DIFFERENTIATION | RECRUITS | BETA-THALASSEMIA | LINEAGE | GENOME-WIDE ASSOCIATION | Erythropoiesis | Fetal Hemoglobin - biosynthesis | Multigene Family | Mi-2 Nucleosome Remodeling and Deacetylase Complex | Humans | Erythroblasts - metabolism | gamma-Globins - metabolism | Protein Isoforms - metabolism | RNA Interference | Transcription, Genetic | gamma-Globins - genetics | Nuclear Proteins - genetics | Down-Regulation | Cells, Cultured | Erythroid Cells - metabolism | Gene Expression Regulation | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | GATA1 Transcription Factor - metabolism | beta-Globins - genetics | Hemoglobinopathies - therapy | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | beta-Globins - metabolism | Fetal Hemoglobin - genetics | K562 Cells | Cell Line, Tumor | Erythroid Precursor Cells - metabolism | Mice | Polymorphism, Single Nucleotide | Protein Isoforms - genetics | Sickle cell anemia | Physiological aspects | Thalassemia | Genetic aspects | Risk factors | Fetal hemoglobin | Medical research | Genotype & phenotype | Hematology | Sickle cell disease | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2009, Volume 36, Issue 4, pp. 682 - 695
Journal Article
Blood, ISSN 0006-4971, 05/2012, Volume 119, Issue 18, pp. 4098 - 4099
In this issue of Blood, White et al provide compelling evidence that the intrinsic apoptotic caspase cascade, while required for megakaryocyte and platelet... 
MEGAKARYOCYTES | HEMATOLOGY | PATHWAY | PLATELET
Journal Article
Molecular Cell, ISSN 1097-2765, 02/2012, Volume 45, Issue 3, pp. 330 - 343
Polycomb repressive complexes (PRCs) play key roles in developmental epigenetic regulation. Yet the mechanisms that target PRCs to specific loci in mammalian... 
TRANSFORMATION | MAINTENANCE | ADULT HEMATOPOIESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | CBFA2 | MEGAKARYOCYTE | MICE | DIFFERENTIATION | RUNX1 | HAPLOINSUFFICIENCY | CELL BIOLOGY | Chromatin - metabolism | Thymocytes - metabolism | Protein Multimerization | Gene Expression Profiling | Core Binding Factor beta Subunit - genetics | Zebrafish - embryology | Gene Knockdown Techniques | T-Lymphocytes - metabolism | Hematopoietic Stem Cells - physiology | Repressor Proteins - isolation & purification | Megakaryocytes - metabolism | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Core Binding Factor beta Subunit - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Core Binding Factor Alpha 2 Subunit - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Polycomb-Group Proteins | Zebrafish - genetics | Mice, Knockout | Animals | Chromatography, Affinity | Polycomb Repressive Complex 1 | Protein Binding | Mice | Ubiquitin-Protein Ligases - genetics | Core Binding Factor Alpha 2 Subunit - genetics | Cluster Analysis | Computer science | Employee recruitment | Chromatin | Genomics | Genes | Stem cells | Chemical properties | DNA binding proteins | Artificial intelligence | Genetic research | Index Medicus
Journal Article
Journal of Hematopathology, ISSN 1868-9256, 9/2015, Volume 8, Issue 3, pp. 169 - 176
A subset of Down syndrome (DS) (trisomy 21) neonates is born with a unique erythromegakaryocytic myeloproliferative disorder that spontaneously resolves over... 
Pathology | Medicine & Public Health | Hematology | Myeloid proliferation | Down syndrome | GATA1 | Myeloproliferative disorder | TRANSCRIPTION FACTORS | HIGH CURE RATE | PATHOLOGY | NATURAL-HISTORY | MEGAKARYOCYTIC LEUKEMIA | CHILDREN | TRANSIENT MYELOPROLIFERATIVE DISORDER | MOUSE MODEL | ACUTE MEGAKARYOBLASTIC LEUKEMIA | DIFFERENTIATION | HEMATOLOGY | GATA1 MUTATIONS
Journal Article
Cell, ISSN 0092-8674, 2010, Volume 142, Issue 1, pp. 133 - 143
Recent genome-wide studies have demonstrated that pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By genetic studies in the zebrafish... 
RNA | DEV BIO | Dev Bio | RNA-POLYMERASE-II | DOMAIN | ZEBRAFISH | HEMATOPOIESIS | EMBRYO | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | PAF1 COMPLEX | GENES | GATA-1 | P-TEFB | CELL BIOLOGY
Journal Article
Journal Article