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1. Full Text Phosphatidylinositol 3‐kinase inhibition potentiates glucocorticoid response in B‐cell acute lymphoblastic leukemia
by Evangelisti, Cecilia and Cappellini, Alessandra and Oliveira, Mariana and Fragoso, Rita and Barata, João T and Bertaina, Alice and Locatelli, Franco and Simioni, Carolina and Neri, Luca M and Chiarini, Francesca and Lonetti, Annalisa and Buontempo, Francesca and Orsini, Ester and Pession, Andrea and Manzoli, Lucia and Martelli, Alberto Maria and Evangelisti, Camilla
Journal of cellular physiology, ISSN 0021-9541, 03/2018, Volume 233, Issue 3, pp. 1796 - 1811
dexamethasone | ALL | targeted therapy | PI3K inhibitors | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dexamethasone | Analysis | Genes | Phospholipids | Acute lymphocytic leukemia | Gene expression | Steroids | TOR protein | Drugs | Glucocorticoids | Leukemia | Gene regulation | Cytotoxicity | AKT protein | Kinases | Signal transduction | Down-regulation | Cell cycle | Inhibition | Translocation | Acute lymphatic leukemia | Stroma | Rapamycin | Tumor cell lines | Lymphatic leukemia | Patients | Nuclear transport | 1-Phosphatidylinositol 3-kinase | Signaling | Inhibitors | Lymphocytes B | Apoptosis | Index Medicus
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2. Full Text Hepatocellular carcinoma as an emerging morbidity in the thalassemia syndromes: A comprehensive review
by Moukhadder, Hassan M and Halawi, Racha and Cappellini, Maria Domenica and Taher, Ali T
Cancer, ISSN 0008-543X, 03/2017, Volume 123, Issue 5, pp. 751 - 758
hepatitis C virus | iron overload | thalassemia | hepatitis B virus | hepatocellular carcinoma | Life Sciences & Biomedicine | Oncology | Science & Technology | Hepatitis C, Chronic - pathology | Carcinoma, Hepatocellular - physiopathology | Hepatitis C, Chronic - diagnostic imaging | Humans | Risk Factors | Carcinogenesis - genetics | Hepatitis C, Chronic - virology | Liver Neoplasms - complications | Hepacivirus - pathogenicity | Thalassemia - virology | Iron Overload - physiopathology | Liver Neoplasms - diagnostic imaging | Carcinoma, Hepatocellular - diagnostic imaging | Hepatitis B, Chronic - diagnostic imaging | Hepatitis B, Chronic - virology | Iron Overload - diagnostic imaging | Carcinoma, Hepatocellular - complications | Liver Neoplasms - physiopathology | Thalassemia - complications | Thalassemia - physiopathology | Hepatitis B, Chronic - pathology | Complications and side effects | Treatment outcome | Usage | Magnetic resonance imaging | Patient outcomes | Analysis | Thalassemia | Research | Hepatoma | Carcinogenesis | Risk factors | Syngeneic grafts | Liver | Vaccination | Genotoxicity | Disorders | Chronic infection | Viruses | Hepatocellular carcinoma | Transplantation | Iron | Infections | Incidence | Prevention | Hepatitis | Liver cancer | Carcinogens | Surgery | Chelation | Attenuation | Hepatitis B virus | Damage | Ultrasound | Magnetic induction | Immunosurveillance | Risk analysis | Patients | Morbidity | Screening | Resonance | Carcinogenicity | Hepatitis C virus | Hepatitis C | Hepatitis B | Liver transplantation | Cancer | Index Medicus | Abridged Index Medicus
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3. Full Text Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-kappa B
by Buontempo, Francesca and Orsini, Ester and Lonetti, Annalisa and Cappellini, Alessandra and Chiarini, Francesca and Evangelisti, Camilla and Evangelisti, Cecilia and Melchionda, Fraia and Pession, Andrea and Bertaina, Alice and Locatelli, Franco and Bertacchini, Jessika and Neri, Luca Maria and McCubrey, James A and Martelli, Alberto Maria
Oncotarget, ISSN 1949-2553, 01/2016, Volume 7, Issue 2, pp. 1323 - 1340
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - blood | Cell Survival - drug effects | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Unfolded Protein Response - drug effects | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Endoplasmic Reticulum Stress - drug effects | Apoptosis - drug effects | Jurkat Cells | Neoplastic Stem Cells - drug effects | Heat-Shock Proteins - metabolism | Humans | Casein Kinase II - antagonists & inhibitors | Bortezomib - pharmacology | Blotting, Western | Drug Synergism | Neoplastic Stem Cells - metabolism | Transcription Factor RelA - metabolism | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - blood | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - blood | Microscopy, Fluorescence | Naphthyridines - pharmacology | Index Medicus
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4. Full Text Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia
by Evangelisti, Cecilia and Cappellini, Alessandra and Oliveira, Mariana and Fragoso, Rita and Barata, João T and Bertaina, Alice and Locatelli, Franco and Simioni, Carolina and Neri, Luca M and Chiarini, Francesca and Lonetti, Annalisa and Buontempo, Francesca and Orsini, Ester and Pession, Andrea and Manzoli, Lucia and Martelli, Alberto Maria and Evangelisti, Camilla
Journal of cellular physiology, 03/2018, Volume 233, Issue 3, p. 1796
Triazines - pharmacology | Apoptosis - drug effects | Heterocyclic Compounds, 3-Ring - pharmacology | Purines - pharmacology | Humans | Child, Preschool | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Quinoxalines - pharmacology | Cell Movement - drug effects | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Dexamethasone - pharmacology | Isoquinolines - pharmacology | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Glucocorticoids - pharmacology | Antineoplastic Agents - pharmacology | Thiazolidinediones - pharmacology | Child | B-Lymphocytes - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Quinazolinones - pharmacology
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5. Full Text How I manage medical complications of b-thalassemia in adults
by Taher, Ali T and Cappellini, Maria Domenica
Blood, ISSN 0006-4971, 10/2018, Volume 132, Issue 17, pp. 1781 - 1791
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6. Full Text Planck 2013 results. I. Overview of products and scientific results
by Ade, P.A.R and Rachen, J.P and Zonca, A and et al and Planck Collaboration and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Astronomy and astrophysics (Berlin), ISSN 0004-6361, 2014, Volume 571, pp. 1 - 48
Space vehicles: instruments | Instrumentation: detectors | Cosmology: observations | Cosmic background radiation | Physical Sciences | Astronomy & Astrophysics | Science & Technology | Polarization | European Space Agency | Planck satellite | Cosmology | Universe | Evolution | Microwaves | Astronomy | Physics - Cosmology and Nongalactic Astrophysics | Sciences of the Universe | Astrophysics | Cosmology and Extra-Galactic Astrophysics | Physics | ASTRONOMY AND ASTROPHYSICS | space vehicles: instruments | cosmology: observations | instrumentation: detectors | cosmic background radiation
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7. Full Text Management of chronic viral hepatitis in patients with thalassemia: Recommendations from an international panel
by Di Marco, Vito and Capra, Marcello and Angelucci, Emanuele and Borgna-Pignatti, Caterina and Telfer, Paul and Harmatz, Paul and Kattamis, Antonis and Prossamariti, Luciano and Filosa, Aldo and Rund, Deborah and Gamberini, Maria Rita and Cianciulli, Paolo and De Montalembert, Marianne and Gagliardotto, Francesco and Foster, Graham and Grangè, Jean Didier and Cassarà, Filippo and Iacono, Angela and Cappellini, Maria Domenica and Brittenham, Gary M and Prati, Daniele and Pietrangelo, Antonello and Craxì, Antonio and Maggio, Aurelio and Italian Assoc Study Liver and Italian Soc Study Thalassemia Haem and Italian Society for the Study of Thalassemia and Haemoglobinopathies and Italian Association for the Study of the Liver and on behalf of the Italian Society for the Study of Thalassemia and Haemoglobinopathies and Italian Association for the Study of the Liver
Blood, ISSN 0006-4971, 10/2010, Volume 116, Issue 16, pp. 2875 - 2883
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Anemias. Hemoglobinopathies | Viral hepatitis | Infectious diseases | Diseases of red blood cells | Viral diseases | Biological and medical sciences | Medical sciences | Human viral diseases | Liver Cirrhosis - diagnosis | Hepatitis B, Chronic - transmission | Antiviral Agents - therapeutic use | Liver Cirrhosis - complications | Humans | Thalassemia - epidemiology | Hepatitis B, Chronic - diagnosis | Hepatitis C, Chronic - complications | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Hepatitis C, Chronic - transmission | Hepatitis B, Chronic - complications | Hepatitis B, Chronic - drug therapy | Thalassemia - complications | Thalassemia - drug therapy | Index Medicus | Abridged Index Medicus
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8. Full Text 3232 Synergistic cytotoxic effects of bortezomib and ck2 inhibitor cx-4945 in acute lymphoblastic leukemia: turning off the prosurvival er chaperone BIP/GRP78 and turning on the proapoptotic NF-κb
by Buontempo, F and Orsini, E and Lonetti, A and Cappellini, A and Chiarini, F and Evangelisti, Camilla and Evangelisti, Cecilia and Pession, A and Bertaina, A and Locatelli, F and McCubrey, J and Martelli, A
European journal of cancer (1990), ISSN 0959-8049, 2015, Volume 51, pp. S659 - S660
Hematology, Oncology and Palliative Medicine
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9. Full Text Sequential Treatment with Ipilimumab and BRAF Inhibitors in Patients With Metastatic Melanoma: Data From the Italian Cohort of the Ipilimumab Expanded Access Program
by Ascierto, Paolo Antonio and Simeone, Ester and Sileni, Vanna Chiarion and Vecchio, Michele Del and Marchetti, Paolo and Cappellini, Gian Carlo Antonini and Ridolfi, Ruggero and de Rosa, Francesco and Cognetti, Francesco and Ferraresi, Virginia and Testori, Alessandro and Queirolo, Paola and Bernengo, Maria Grazia and Guida, Michele and Galli, Luca and Mandalà, Mario and Cimminiello, Carolina and Rinaldi, Gaetana and Carnevale-Schianca, Fabrizio and Maio, Michele
Cancer investigation, ISSN 0735-7907, 5/2014, Volume 32, Issue 4, pp. 144 - 149
Treatment | Molecular biology | Cutaneous melanoma | Tumor immunology | Life Sciences & Biomedicine | Oncology | Science & Technology | Skin Neoplasms - drug therapy | Humans | Ipilimumab | Middle Aged | Oximes - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Imidazoles - administration & dosage | Melanoma - enzymology | Male | Molecular Targeted Therapy | Indoles - administration & dosage | Young Adult | Skin Neoplasms - enzymology | Time Factors | Melanoma - genetics | Skin Neoplasms - mortality | Aged, 80 and over | Adult | Female | Retrospective Studies | Proto-Oncogene Proteins B-raf - metabolism | Skin Neoplasms - pathology | Drug Administration Schedule | Kaplan-Meier Estimate | Treatment Outcome | Disease Progression | Melanoma - secondary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Skin Neoplasms - genetics | Italy | Aged | Mutation | Sulfonamides - administration & dosage | Melanoma - mortality | Index Medicus
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10. Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor
by Caporali, Simona and Alvino, Ester and Lacal, Pedro Miguel and Levati, Lauretta and Giurato, Giorgio and Memoli, Domenico and Caprini, Elisabetta and Cappellini, Gian Carlo Antonini and D'Atri, Stefania
International journal of oncology, ISSN 1019-6439, 09/2016, Volume 49, Issue 3, pp. 1164 - 1174
GSK2126458A | Melanoma | Dabrafenib | BRAF | Drug resistance | Invasion | Bevacizumab | Life Sciences & Biomedicine | Oncology | Science & Technology | Melanoma - metabolism | TOR Serine-Threonine Kinases - metabolism | Neoplasm Invasiveness | Humans | Imidazoles - pharmacology | Phosphatidylinositol 3-Kinases - metabolism | Cell Movement - drug effects | Signal Transduction - drug effects | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Oximes - pharmacology | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Mutation | Proto-Oncogene Proteins B-raf - metabolism | Drug Resistance, Neoplasm - drug effects
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