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1. Full Text Assessment of the Incremental Diagnostic Value of Florbetapir F 18 Imaging in Patients With Cognitive Impairment: The Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Study
by Boccardi, Marina and Altomare, Daniele and Ferrari, Clarissa and Festari, Cristina and Guerra, Ugo Paolo and Paghera, Barbara and Pizzocaro, Claudio and Lussignoli, Giulia and Geroldi, Cristina and Zanetti, Orazio and Cotelli, Maria Sofia and Turla, Marinella and Borroni, Barbara and Rozzini, Luca and Mirabile, Dario and Defanti, Carlo and Gennuso, Michele and Prelle, Alessandro and Gentile, Simona and Morandi, Alessandro and Vollaro, Stefano and Volta, Giorgio Dalla and Bianchetti, Angelo and Conti, Marta Zaffira and Cappuccio, Melania and Carbone, Pasqualina and Bellandi, Daniele and Abruzzi, Luciano and Bettoni, Luigi and Villani, Daniele and Raimondi, Maria Clara and Lanari, Alessia and Ciccone, Alfonso and Facchi, Emanuela and Di Fazio, Ignazio and Rozzini, Renzo and Boffelli, Stefano and Manzoni, Laura and Salvi, Giovanni Pietro and Cavaliere, Sabina and Belotti, Gloria and Avanzi, Stefano and Pasqualetti, Patrizio and Muscio, Cristina and Padovani, Alessandro and Frisoni, Giovanni B and Incremental Diagnostic Value and Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Working Group and for the Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Working Group
JAMA Neurology, ISSN 2168-6149, 12/2016, Volume 73, Issue 12, pp. 1417 - 1424
IMPORTANCE: Cerebral amyloidosis is a key abnormality in Alzheimer disease (AD) and can be detected in vivo with positron emission tomography (PET) ligands.... 
DONEPEZIL | CRITERIA | IMPACT | AUTOPSY | RECOMMENDATIONS | DISEASE | HYPOTHESIS | STATE | BETA PLAQUES | MODERATE ALZHEIMER DEMENTIA | CLINICAL NEUROLOGY | Predictive Value of Tests | Aniline Compounds | Cognitive Dysfunction - metabolism | Humans | Male | Positron-Emission Tomography - methods | Alzheimer Disease - diagnosis | Ethylene Glycols | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Positron-Emission Tomography - standards | Aged, 80 and over | Female | Aged | Cognitive Dysfunction - diagnosis | Alzheimer Disease - diagnostic imaging | Cognitive Dysfunction - diagnostic imaging
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2. Full Text Genome-wide association study identifies 74 loci associated with educational attainment
by Okbay, Aysu and Beauchamp, Jonathan and Fontana, M.A and Lee, James J and Pers, Tune and Rietveld, C.A and Turley, Patrick and Chen, G.-B and Emilsson, Valur and Meddens, S.F.W and Oskarsson, S and Pickrell, J.K and Thom, K and Timshel, P and Vlaming, Ronald and Abdellaoui, Abdel and Ahluwalia, Tarunveer Singh and Bacelis, Jonas and Baumbach, Clemens and Bjornsdottir, G and Brandsma, Johan and Pina Concas, M and Derringer, J and Furlotte, N.A and Galesloot, Tessel and Girotto, S and Gupta, R and Hall, Leanne M and Harris, Sarah and Hofer, E and Horikoshi, M and Huffman, Jennifer E and Kaasik, K and Kalafati, Ioanna-Panagiota and Karlsson, Robert and Kong, Augustine and Lahti, Jari and Lee, Sven and Deleeuw, C and Lind, Penelope and Lindgren, K.-O and Liu, T and Mangino, Massimo and Marten, Jonathan and Mihailov, Evelin and Miller, Mike and Most, Peter and Oldmeadow, Christopher and Payton, Antony and Pervjakova, Natalia and Peyrot, Wouter and Qian, Y and Raitakari, Olli and Rueedi, R and Salvi, E and Schmidt, B and Schraut, K.E and Shi, J and Smith, Albert Vernon and Poot, Raymond and St Pourcain, Beate and Teumer, Alexander and Thorleifsson, Gudmar and Verweij, Niek and Vuckovic, gana and Wellmann, J and Westra, Harm-Jan and Yang, J and Zhao, W and Zhu, Z and Alizadeh, Behrooz and Amin, Najaf and Bakshi, A and Baumeister, Sebastian and Biino, Ginevra and Bønnelykke, Klaus and Boyle, Patricia and Campbell, Harry and Cappuccio, F.P and Davies, Gail and Neve, Jan-Emmanuel and Deloukas, Panagiotis and Demuth, Ilja and Ding, J and Eibich, P and Eisele, L and Eklund, Niina and Evans, David and Faul, Jessica D and Feitosa, Mary Furlan and Forstner, Aneas and Gandin, Ilaria and Gunnarsson, B and Halldorsson, Bjarni and Harris, Tamara and Holliday, Elizabeth and Heath, Anew C and Hocking, L.J and Homuth, Georg and Horan, Mike and ... and LifeLines Cohort Study and Humanistisk-samhällsvetenskapliga vetenskapsområdet and Uppsala universitet and Statsvetenskapliga institutionen and Samhällsvetenskapliga fakulteten
Nature: international weekly journal of science, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 539 - 542
textabstractEducational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least... 
ACHIEVEMENT | TRAITS | MULTIDISCIPLINARY SCIENCES | HERITABILITY | Genome-Wide Association Study | Gene Expression Regulation - genetics | Humans | Molecular Sequence Annotation | Computational Biology | Fetus - metabolism | United Kingdom | Cognition | Educational Status | Bipolar Disorder - genetics | Gene-Environment Interaction | Brain - metabolism | Schizophrenia - genetics | Polymorphism, Single Nucleotide - genetics | Alzheimer Disease - genetics | Quantitative trait loci | Academic achievement | Genome-wide association studies | Genetic aspects | Observations | Studies | Genomes | Gene expression | Genes | Educational attainment | Meta-analysis | Quantitative Finance | Samhällsvetenskap | Biological Sciences | Social Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
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3. Full Text Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
by Speliotes, Elizabeth and Willer, Cristen and Berndt, Sonja and Monda, Keri and Thorleifsson, Gudmar and Jackson, Anne and Allen, H.L and Lindgren, Cecilia and Luan, J and Mägi, Reedik and Randall, Joshua and Vedantam, Sailaja and Winkler, Thomas and Qi, Lu and Workalemahu, Tsegaselassie and Heid, Iris and Steinthorsdottir, Valgerdur and Stringham, Heather and Wheeler, Eleanor and Wood, Anew and Ferreira, Teresa and Weyant, Robert and Segrè, Ayellet and Eestrada, Karol and Liang, Liming and Nemesh, James and Park, J.H and Gustafsson, Stefan and Kilpeläinen, Tuomas and Yang, Joanna and Bouatia-Naji, Nabila and Eesko, Tõnu and Feitosa, Mary Furlan and Kutalik, Zoltán and Mangino, Massimo and Raychaudhuri, Soumya and Scherag, Ane and Smith, Albert Vernon and Welch, Ryan and Zhao, Jing Hua and Aben, Katja and Absher, Devin and Amin, Najaf and Dixon, Anna and Fisher, Eeva and Glazer, Nicole and Goddard, Michael and Heard-Costa, Nancy and Hoesel, Volker and Hottenga, Jouke Jan and Johansson, Åsa and Johnson, Toby and Ketkar, Shamika and Lamina, Claudia and Li, Shengxu and Moffatt, Miriam and Myers, Richard and Narisu, Narisu and Perry, John and Peters, Marjolein and Preuss, Michael and Ripatti, Samuli and Rivadeneira Ramirez, Fernando and Sandholt, Camilla and Scott, Laura and Timpson, Nicholas and Tyrer, Jonathan and Wingerden, Sophie and White, Charles and Wiklund, Freik and Barlassina, Christina and Chasman, Daniel and Cooper, Matthew and Jansson, J.O and Lawrence, Robert and Pellikka, Niina and Prokopenko, Inga and Shi, Jianxin and Thiering, Eelisabeth and Alavere, Helene and Alibrandi, Maria and Almgren, Peter and Arnold, Alice and Aspelund, Thor and Atwood, Larry and Balkau, Beverley and Balmforth, Anthony and Bennett, Amanda and Ben-Shlomo, Y and Bergman, Richard and Bergmann, Sven and Biebermann, Heike and Blakemore, Alexana and Boes, Tanja and Bonnycastle, Lori and Bornstein, Stefan and Brown, Morris and Buchanan, Thomas and Busonero, F and Campbell, Harry and ... and MAGIC and Procardis Consortium and on behalf of Procardis Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 11/2010, Volume 42, Issue 11, pp. 937 - 948
textabstractObesity is globaLy prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity... 
COMMON VARIANTS | OBESITY | METAANALYSIS | FTO GENE | GLUCOSE | GENETICS & HEREDITY | EARLY-ONSET | GASTRIC-INHIBITORY POLYPEPTIDE | WEIGHT | FAT MASS | GENOME-WIDE ASSOCIATION | Body Mass Index | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Body Size - genetics | Chromosome Mapping | Polymorphism, Single Nucleotide | Body Weight - genetics | Obesity - genetics | Body Height - genetics | Measurement | Body mass index | Obesity | Genetic aspects | Research | Risk factors | Studies | Medical research | Hospitals | Biomedical research | Councils | Risk assessment | Genetics | Charitable foundations | Public health | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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4. Full Text Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
by Lee, J.J and Wedow, R and Okbay, A and Kong, E and Maghzian, O and Zacher, M and Galesloot, T.E and Kiemeney, L.A.L.M and Franke, B and Benjamin, D.J and Cesarini, D and 23Me Res Team and Social Sci Genetic Assoc Consortiu and COGENT Cognitive Genomics Consorti and 23andMe Research Team and COGENT (Cognitive Genomics Consortium) and Social Science Genetic Association Consortium and Humanistisk-samhällsvetenskapliga vetenskapsområdet and Uppsala universitet and Statsvetenskapliga institutionen and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 2018, Volume 50, Issue 8, pp. 1112 - 1121
Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1 million individuals and identify 1,271... 
INTELLIGENCE | HUMAN TRAITS | HUMAN BRAIN | METAANALYSIS | GWAS | STATISTICS | GENETICS & HEREDITY | POPULATIONS | LOCI | MAPPING CAUSAL VARIANTS | HERITABILITY | Humans | Middle Aged | Male | Educational Status | Multifactorial Inheritance | Phenotype | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Cohort Studies | Cell interaction | Genome-wide association studies | Usage | Analysis | Multifactorial traits | Research | Health education | Brain | Phenotypes | Dosage compensation | Sample size | Cognitive ability | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Estimates | Environmental effects | Educational attainment | Meta-analysis | Consortia | Education | Genetic analysis | Heritability | Basic Medicine | Medical Genetics | Medicinsk genetik | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Natural Sciences
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5. Full Text Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
by Sabatine, Marc S and Giugliano, Robert P and Keech, Anthony C and Honarpour, Narimon and Wiviott, Stephen D and Murphy, Sabina A and Kuder, Julia F and Wang, Huei and Liu, Thomas and Wasserman, Scott M and Sever, Peter S and Pedersen, Terje R and FOURIER Steering Comm Investigator and FOURIER Steering Committee and Investigators
The New England Journal of Medicine, ISSN 0028-4793, 05/2017, Volume 376, Issue 18, pp. 1713 - 1722
In this trial, 27,564 patients with cardiovascular disease and LDL cholesterol levels of 70 mg per deciliter or higher on statin therapy were assigned to... 
MODERATE | MEDICINE, GENERAL & INTERNAL | STATIN THERAPY | LDL-C | REDUCING LIPIDS | PCSK9 INHIBITION | RISK | PLACEBO-CONTROLLED TRIAL | HYPERCHOLESTEROLEMIA | CORONARY-HEART-DISEASE | EZETIMIBE | Atherosclerosis - drug therapy | Double-Blind Method | Follow-Up Studies | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Hypercholesterolemia - drug therapy | Anticholesteremic Agents - adverse effects | Incidence | Cardiovascular Diseases - complications | Anticholesteremic Agents - therapeutic use | Proprotein Convertase 9 - antagonists & inhibitors | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Least-Squares Analysis | Cholesterol, LDL - blood | Female | Hypercholesterolemia - complications | Aged | Drug Therapy, Combination | Prevention | Treatment outcome | Cardiovascular diseases | Drug therapy | Analysis | Stroke | Monoclonal antibodies | Cardiovascular disease | Patients | Drug dosages | Low density lipoprotein | Statins | Clinical outcomes | Cholesterol | Life Sciences | Human health and pathology
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