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1. Full Text DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements
by Natale, F and Scholl, A and Rapp, A and Yu, W and Rausch, C and Cardoso, MC
EPIGENETICS & CHROMATIN, ISSN 1756-8935, 10/2018, Volume 11, Issue 1, pp. 61 - 18
BackgroundPreservation of genome integrity by complete, error-free DNA duplication prior to cell division and by correct DNA damage repair is paramount for the... 
DNA replication | Immuno-FISH | HUMAN-CELLS | IN-SITU HYBRIDIZATION | STABLE UNITS | DOUBLE-STRAND BREAKS | L1 RETROTRANSPOSITION | Alu | DNA repair | ORGANIZATION | CHROMOSOME | Satellites | DNA repetitive elements | LINE | HETEROCHROMATIN | SEQUENCE | GENETICS & HEREDITY | Phosphorylated H2AX | TRIMERIC STRUCTURE | ChIP-Seq | Genome-wide analysis | DNA, Satellite | Cell Line | Animals | Long Interspersed Nucleotide Elements | DNA Repair | Humans | DNA Replication | Histone Code | Mice | HeLa Cells | Alu Elements | Satellite DNA | Genomes | Research | Chromatin | Preservation | DNA damage | Genes | Cell division | RNA polymerase | Hybridization | Artificial chromosomes | Double-strand break repair | DNA biosynthesis | Proteins | Heterochromatin | Alu elements | Epigenetics | Replication | Immunofluorescence | Deoxyribonucleic acid--DNA
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2. Full Text DNA replication dynamics of vole genome and its epigenetic regulation
by Heinz, Kathrin S and Rapp, Alexander and Casas-Delucchi, Corella S and Lehmkuhl, Anne and Romero-Fernández, Ismael and Sánchez, Antonio and Krämer, Oliver H and Marchal, J. Alberto and Cardoso, M. Cristina
Epigenetics and Chromatin, ISSN 1756-8935, 03/2019, Volume 12, Issue 1, pp. 18 - 21
BackgroundThe genome of some vole rodents exhibit large blocks of heterochromatin coupled to their sex chromosomes. The DNA composition and transcriptional... 
DNA replication dynamics | HDAC inhibition | Heterochromatin | Epigenetic composition | Site-directed targeting | Histone acetylation | Microtus cabrerae | Giant sex chromosomes | LOCALIZATION | X-CHROMOSOME | SEQUENCES | SEX-CHROMOSOMES | INTERPHASE | MICROTUS | ORIGIN | GENETICS & HEREDITY | DOMAINS | BINDING | Epigenetic inheritance | DNA replication | Genomics | DNA | Genetic aspects | Research | Genetic regulation | Sex chromosomes | Yeast | Transcription | Genomes | Histone acetyltransferase | DNA biosynthesis | Proteins | Molecular modelling | X Chromosomes | Cell cycle | Epigenetics | Replication | Cytosine | Acetylation | Localization | Chromosomes | Deoxyribonucleic acid--DNA
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3. Full Text The size of the proton
by Pohl, Randolf and Antognini, Aldo and Nez, François and Amaro, Fernando D and Biraben, François and Cardoso, João M. R and Covita, Daniel S and Dax, Andreas and Dhawan, Satish and Fernandes, Luis M. P and Giesen, Adolf and Graf, Thomas and Hänsch, Theodor W and Indelicato, Paul and Julien, Lucile and Kao, Cheng-Yang and Knowles, Paul and Le Bigot, Eric-Olivier and Liu, Yi-Wei and Lopes, José A. M and Ludhova, Livia and Monteiro, Cristina M. B and Mulhauser, Françoise and Nebel, Tobias and Rabinowitz, Paul and Dos Santos, Joaquim M. F and Schaller, Lukas A and Schuhmann, Karsten and Schwob, Catherine and Taqqu, David and Veloso, João F. C. A and Kottmann, Franz
Nature, ISSN 0028-0836, 07/2010, Volume 466, Issue 7303, pp. 213 - 216
The proton is the primary building block of the visible Universe, but many of its properties-such as its charge radius and its anomalous magneticmoment-are not... 
RYDBERG CONSTANT | LAMB-SHIFT EXPERIMENT | RADIUS | LASER | MULTIDISCIPLINARY SCIENCES | FREQUENCY | ATOMS | MUONIC HYDROGEN | DEUTERIUM | Protons | Electrodynamics | Research | Properties | Lasers | Spectrum analysis | Light | Spectroscopy | Mathematical analysis | Scattering | Charge | Standard deviation | Physical properties | Lamb | Muons | Atomic Physics | Physics
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4. Full Text Proton Structure from the Measurement of 2S-2P Transition Frequencies of Muonic Hydrogen
by Aldo Antognini and François Nez and Karsten Schuhmann and Fernando D. Amaro and François Biraben and João M. R. Cardoso and Daniel S. Covita and Andreas Dax and Satish Dhawan and Marc Diepold and Luis M. P. Fernandes and Adolf Giesen and Andrea L. Gouvea and Thomas Graf and Theodor W. Hänsch and Paul Indelicato and Lucile Julien and Cheng-Yang Kao and Paul Knowles and Franz Kottmann and Eric-Olivier Le Bigot and Yi-Wei Liu and José A. M. Lopes and Livia Ludhova and Cristina M. B. Monteiro and Françoise Mulhauser and Tobias Nebel and Paul Rabinowitz and Joaquim M. F. dos Santos and Lukas A. Schaller and Catherine Schwob and David Taqqu and João F. C. A. Veloso and Jan Vogelsang and Randolf Pohl
Science, ISSN 0036-8075, 1/2013, Volume 339, Issue 6118, pp. 417 - 420
Accurate knowledge of the charge and Zemach radii of the proton is essential, not only for understanding its structure but also as input for tests of... 
Protons | Energy levels | Lasers | Hydrogen | RESEARCH ARTICLES | Quantum electrodynamics | Laser spectroscopy | Magnetism | Puzzles | Muons | Electrons | ZEMACH | RADIUS | MULTIDISCIPLINARY SCIENCES | SIZE | ATOMS | POLARIZABILITY CONTRIBUTION | LAMB SHIFT | Nuclear structure | Atomic properties | Research | Properties | Magnetization | Scattering | Spectral lines | Charge | Atomic radius | Muonium
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5. Full Text Laser spectroscopy of muonic deuterium
by Pohl, Randolf and Nez, François and Fernandes, Luis M.P and Amaro, Fernando D and Biraben, François and Cardoso, João M.R and Covita, Daniel S and Dax, Andreas and Dhawan, Satish and Diepold, Marc and Giesen, Adolf and Gouvea, Andrea L and Graf, Thomas and Hänsch, Theodor W and Indelicato, Paul and Julien, Lucile and Knowles, Paul and Kottmann, Franz and Le Bigot, Eric-Olivier and Liu, Yi-Wei and Lopes, José A.M and Ludhova, Livia and Monteiro, Cristina M.B and Mulhauser, Françoise and Nebel, Tobias and Rabinowitz, Paul and Dos Santos, Joaquim M.F and Schaller, Lukas A and Schuhmann, Karsten and Schwob, Catherine and Taqqu, David and Veloso, João F.C.A and Antognini, Aldo and CREMA Collaboration and The CREMA Collaboration
Science, ISSN 0036-8075, 08/2016, Volume 353, Issue 6300, pp. 669 - 673
The deuteron is the simplest compound nucleus, composed of one proton and one neutron. Deuteron properties such as the root-mean-square charge radius r(d) and... 
HYDROGEN | PROTON RADIUS PUZZLE | MULTIDISCIPLINARY SCIENCES | LAMB SHIFT | ELASTIC-SCATTERING | Deuterium | Spectroscopy | Deuterons | Hydrogen | Charge | Electronics | Nuclei (nuclear physics) | Nuclei
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6. Nanobodies and recombinant binders in cell biology
by Jonas Helma and M Cristina Cardoso and Serge Muyldermans and Heinrich Leonhardt
The Journal of Cell Biology, ISSN 0021-9525, 06/2015, Volume 209, Issue 5, p. 633
  Antibodies are key reagents to investigate cellular processes. The development of recombinant antibodies and binders derived from natural protein scaffolds... 
Proteins | Immunoassay | Immunoglobulins | Cellular biology | Fluorescence | Genetics
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7. Full Text Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules
by Herce, Henry D and Garcia, Angel E and Cardoso, M. Cristina
Journal of the American Chemical Society, ISSN 0002-7863, 12/2014, Volume 136, Issue 50, pp. 17459 - 17467
Guanidinium-rich molecules, such as cell-penetrating peptides, efficiently enter living cells in a non-endocytic energy-independent manner and transport a wide... 
TRANSLOCATION | CELLS | PROTEIN | HIV-1 TAT | PORE FORMATION | LIPID-MEMBRANES | PLASMA-MEMBRANE | FREE-ENERGY | CHEMISTRY, MULTIDISCIPLINARY | PENETRATING PEPTIDES | DELIVERY | Fatty Acids - chemistry | Guanidine - chemistry | Computer Simulation | Humans | Cells, Cultured | Hydrophobic and Hydrophilic Interactions | Guanidine - metabolism | Cell-Penetrating Peptides - chemistry | Cell-Penetrating Peptides - metabolism | Hydrogen-Ion Concentration | Hydrophobicity | Chemical properties | Hydrogen-ion concentration | Fatty acids | Analysis | Electric properties
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8. Nanobodies and recombinant binders in cell biology
by Helma, Jonas and Cardoso, M Cristina and Muyldermans, Serge and Leonhardt, Heinrich
Journal of Cell Biology, ISSN 0021-9525, 06/2015, Volume 209, Issue 5, pp. 633 - 633
Antibodies are key reagents to investigate cellular processes. The development of recombinant antibodies and binders derived from natural protein scaffolds has... 
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9. Full Text High-resolution analysis of mammalian dna replication units
by Chagin, Vadim O and Reinhart, Marius and Cristina Cardoso, M
Methods in Molecular Biology, ISSN 1064-3745, 2015, Volume 1300, pp. 43 - 65
Genomic DNA of a eukaryotic cell is replicated once during the S-phase of the cell cycle to precisely maintain the complete genetic information. In the course... 
3D-SIM | Immunofluorescence staining | DNA replication | Fluorescent protein | Replication foci | Confocal microscopy | Nucleotide incorporation | High-resolution fluorescence microscopy | Mammals - metabolism | Animals | Microscopy, Fluorescence - methods | DNA Replication - drug effects | Hypotonic Solutions - pharmacology | Cell Membrane Permeability - drug effects | Humans | Staining and Labeling | Cells, Cultured | Mice | DNA - metabolism | Nucleotides - metabolism
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10. ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair
by Gracheva, Ekaterina and Chitale, Shalaka and Wilhelm, Thomas and Rapp, Alexander and Byrne, Jonathan and Stadler, Jens and Medina, Rebeca and Cardoso, M Cristina and Richly, Holger
Journal of Cell Biology, ISSN 0021-9525, 04/2016, Volume 213, Issue 2, pp. 185 - 185
Faithful DNA repair is essential to maintain genome integrity. Ultraviolet (UV) irradiation elicits both the recruitment of DNA repair factors and the... 
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11. Discrimination of Kinetic Models by a Combination of Microirradiation and Fluorescence Photobleaching
by Laurin Lengert and Nicor Lengert and Barbara Drossel and M Cristina Cardoso and Britta Muster and Danny Nowak and Alexander Rapp
Biophysical Journal, ISSN 0006-3495, 10/2015, Volume 109, Issue 8, p. 1551
  Fluorescence recovery after photobleaching (FRAP) is an excellent tool to measure the chemical rate constants of fluorescently labeled proteins in living... 
Proteins | Radiation | Fluorescence | Kinetics | Deoxyribonucleic acid--DNA
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12. Full Text Nanobodies and recombinant binders in cell biology
by Helma, Jonas and Cardoso, M. Cristina and Muyldermans, Serge and Leonhardt, Heinrich
Journal of Cell Biology, ISSN 0021-9525, 2015, Volume 209, Issue 5, pp. 633 - 644
Antibodies are key reagents to investigate cellular processes. The development of recombinant antibodies and binders derived from natural protein scaffolds has... 
HEAVY-CHAIN ANTIBODIES | CONFORMATIONAL-CHANGES | CRYSTAL-STRUCTURE | MOLECULAR RECOGNITION | IN-VIVO | COMBINATORIAL LIBRARIES | ANKYRIN REPEAT PROTEINS | SINGLE-DOMAIN ANTIBODIES | BINDING-PROTEINS | LIVING CELLS | CELL BIOLOGY | Gene Expression | Animals | Immunoprecipitation - methods | Single-Domain Antibodies - metabolism | Single-Domain Antibodies - chemistry | Fluorescent Antibody Technique - methods | Humans | Single-Domain Antibodies - genetics | Protein Array Analysis - methods | Cell Biology | Viral antibodies | Antibodies | Cell interaction | Health aspects | Identification and classification | Protein-protein interactions | Reviews
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13. Full Text Occurrence of pharmaceuticals in a water supply system and related human health risk assessment
by de Jesus Gaffney, Vanessa and Almeida, Cristina M.M and Rodrigues, Alexandre and Ferreira, Elisabete and Benoliel, Maria João and Cardoso, Vitor Vale
Water Research, ISSN 0043-1354, 04/2015, Volume 72, pp. 199 - 208
A monitoring study of 31 pharmaceuticals along Lisbon's drinking water supply system was implemented, which comprised the analysis of 250 samples including raw... 
Drinking water | Indicators | Risk assessment | Pharmaceuticals | TRANSFORMATION | WATER RESOURCES | CHALLENGES | ISSUES | ENVIRONMENTAL SCIENCES | REMOVAL | ENGINEERING, ENVIRONMENTAL | DRINKING-WATER | SURFACE WATERS | TOXICOLOGICAL RELEVANCE | Risk Assessment | Health | Humans | Child, Preschool | Infant | Water Pollutants, Chemical - analysis | Portugal | Young Adult | Tandem Mass Spectrometry | Adolescent | Drinking Water - chemistry | Adult | Water Supply | Pharmaceutical Preparations - analysis | Child | Infant, Newborn | Drugs | Water, Underground | Water-supply | Aquatic resources | Health risk assessment | Health aspects | Human | Groundwater | Raw | Monitoring
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14. ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair
by Ekaterina Gracheva and Shalaka Chitale and Thomas Wilhelm and Alexander Rapp and Jonathan Byrne and Jens Stadler and Rebeca Medina and M Cristina Cardoso and Holger Richly
The Journal of Cell Biology, ISSN 0021-9525, 04/2016, Volume 213, Issue 2, p. 185
  Faithful DNA repair is essential to maintain genome integrity. Ultraviolet (UV) irradiation elicits both the recruitment of DNA repair factors and the... 
Proteins | Chromatin | Ultraviolet radiation | Epigenetics | Genomes | DNA repair
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15. Full Text Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain
by Frauer, Carina and Hoffmann, Thomas and Bultmann, Sebastian and Casa, Valentina and Cardoso, M. Cristina and Antes, Iris and Leonhardt, Heinrich
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e21306
Recent discovery of 5-hydroxymethylcytosine (5hmC) in genomic DNA raises the question how this sixth base is recognized by cellular proteins. In contrast to... 
MOLECULAR-DYNAMICS | HEMI-METHYLATED DNA | METHYLTRANSFERASE | 5-METHYLCYTOSINE | CONVERSION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | CPG | PROTEINS | MAMMALIAN-CELLS | BINDING | CCAAT-Enhancer-Binding Proteins - metabolism | Protein Structure, Tertiary | Cytosine - analogs & derivatives | Humans | DNA - metabolism | Molecular Dynamics Simulation | Thermodynamics | DNA - chemistry | 5-Methylcytosine - metabolism | Hydrogen Bonding | Cytosine - metabolism | HEK293 Cells | CpG Islands - genetics | Protein Binding | CCAAT-Enhancer-Binding Proteins - chemistry | Binding Sites | Cellular proteins | Epigenetic inheritance | Pyrimidines | Hydroxides | Hydrogen | DNA | Crystals | Molecular dynamics | Structure | Methylation | Hydrogen bonding | Competition | Molecular structure | Physical chemistry | Biology | Proteins | Methyl-CpG binding protein | Hydrogen bonds | DNA methylation | Life sciences | Cytosine | Deoxyribonucleic acid--DNA | Hydroxyl groups | Crystal structure | CpG islands | Mammals | Gene expression | Substrates | Physics | Studies | Algorithms | MeCP2 protein | Stem cells | Epigenetics | Deoxyribonucleic acid
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16. Chlorination and oxidation of sulfonamides by free chlorine: Identification and behaviour of reaction products by UPLC-MS/MS
by Gaffney, Vanessa De Jesus and Cardoso, Vitor Vale and Benoliel, Maria João and Almeida, Cristina M M
Journal of environmental management, ISSN 0301-4797, 01/2016, Volume 166, pp. 466 - 466
Sulfonamides (SAs) are one class of the most widely used antibiotics around the world and have been frequently detected in municipal wastewater and surface... 
Water treatment plants | Antibiotics | Chlorine | Oxidation
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17. Full Text Targeted Manipulation/Repositioning of Subcellular Structures and Molecules
by Heinz, Kathrin S and Cardoso, M Cristina
Methods in molecular biology (Clifton, N.J.), 2019, Volume 2038, p. 199
Technical advances in live-cell imaging have made cell biology into a highly dynamic field, allowing the visualization and quantification of complex processes... 
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