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by Jones, G.T and Tromp, G and Kuivaniemi, H and Gretarsdottir, S and Baas, A.F and Giusti, B and Strauss, E and Hof, F.N. van 't and Webb, T.R and Erdman, R and Ritchie, M.D and Elmore, J.R and Verma, A and Pendergrass, S and Kullo, I.J and Ye, Z and Peissig, P.L and Gottesman, O and Verma, S.S and Malinowski, J and Rasmussen-Torvik, L.J and Borthwick, K.M and Smelser, D.T and Crosslin, D.R and Anade, M. de and Ryer, E.J and McCarty, C.A and Bottinger, E.P and Pacheco, J.A and Crawford, D.C and Carrell, D.S and Gerhard, G.S and Franklin, D.P and Carey, D.J and Phillips, V.L and Williams, M.J and Wei, W and Blair, R and Hill, A.A and Vasudevan, T.M and Lewis, D.R and Thomson, I.A and Krysa, J and Hill, G.B and Roake, J and Merriman, T.R and Oszkinis, G and Galora, S and Saracini, C and Abbate, R and Pulli, R and Pratesi, C and Saratzis, A and Verissimo, A.R and Bumpstead, S and Badger, S.A and Clough, R.E and Cockerill, G and Hafez, H and Scott, D.J and Futers, T.S and Romaine, S.P and Bridge, K and Griffin, K.J and Bailey, M.A and Smith, A and Thompson, M.M and Bockxmeer, F.M. van and Matthiasson, S.E and Thorleifsson, G and Thorsteinsdottir, U and Blankensteijn, J.D and Teijink, J.A and Wijmenga, C and Graaf, J. de and Kiemeney, L.A.L.M and Lindholt, J.S and Hughes, A and Bradley, D.T and Stirrups, K and Golledge, J and Norman, P.E and Powell, J.T and Humphries, S.E and Hamby, S.E and Goodall, A.H and Nelson, C.P and Sakalihasan, N and Courtois, A and Ferrell, R.E and Eriksson, P and Folkersen, L and Franco-Cereceda, A and Eicher, J.D and Johnson, A.D and Betsholtz, C and Ruusalepp, A and Franzen, O and Schadt, E.E and Bjorkegren, J.L and ... and Cardiogenics Consortium and Int Consortium Blood Pressure and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Vaskulärbiologi
Circulation Research, ISSN 0009-7330, 2017, Volume 120, Issue 2, pp. 341 - 353
RATIONALE: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci... 
computational biology | meta-analysis | genetics | aortic aneurysm abdominal | matrix metalloproteinases | genome-wide association study | C-REACTIVE PROTEIN | TRANSCRIPTION FACTORS | CARDIAC & CARDIOVASCULAR SYSTEMS | SEQUENCE VARIANT | aortic aneurysm, abdominal | SUSCEPTIBILITY LOCI | ELECTRONIC MEDICAL-RECORDS | HUMAN PREFRONTAL CORTEX | DENSITY-LIPOPROTEIN CHOLESTEROL | PERIPHERAL VASCULAR DISEASE | CANDIDATE GENE ASSOCIATION | HEMATOLOGY | RECEPTOR-RELATED PROTEIN-1 | CORONARY-ARTERY-DISEASE | Aortic Aneurysm, Abdominal - diagnosis | Genetic Predisposition to Disease - genetics | Humans | Genetic Loci - genetics | Genome-Wide Association Study - trends | Aortic Aneurysm, Abdominal - genetics | Genetic Variation - genetics | Aortic Aneurysm, Abdominal - epidemiology | Genetic Predisposition to Disease - epidemiology | Genome-Wide Association Study - methods | Diabetes mellitus | Coronary artery | Aneurysm | Aneurysms | Lipids | Cardiovascular disease | Genomes | Single-nucleotide polymorphism | Risk factors | Gelatinase B | Chromosome 1 | Interleukin 6 | Interleukin 6 receptors | Aorta | Lipoprotein (low density) receptors | Blood pressure | Chromosome 13 | Heritability | Cardiovascular diseases | Heart diseases | 10082 | Clinical Track | 10084 | 10185 | 10195 | 10014 | Medical and Health Sciences | Hematology | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | aortic aneurysm | Hematologi | abdominal
Journal Article
Bone, ISSN 8756-3282, 2008, Volume 42, Issue 5, pp. 969 - 981
Journal Article
by Jones, Gregory T and Tromp, Gerard and Kuivaniemi, Helena and Gretarsdottir, Solveig and Baas, Annette F and Giusti, Betti and Strauss, Ewa and van't Hof, Femke N. G and Webb, Thomas R and Erdman, Robert and Ritchie, Marylyn D and Elmore, James R and Verma, Anurag and Pendergrass, Sarah A and Kullo, Iftikhar J and Zy, Zi Ye and Peissig, Peggy L and Gottesman, Omri and Verma, Shefali S and Malinowski, Jennifer and Rasmussen-Torvik, Laura J and Borthwick, Kenneth M and Smelser, Diane T and Crosslin, David R and de Anade, Mariza and Ryer, Evan J and McCarty, Catherine A and Bottinger, Erwin P and Pacheco, Jennifer A and Crawford, Dana C and Carrell, David S and Gerhard, Glenn S and Franklin, David P and Carey, David J and Phillips, Victoria L and Williams, Michael J. A and Wei, Wenhua and Blair, Ross and Hill, Anew A and Vasudevan, Thodor M and Lewis, David R and Thomson, Ian A and Krysa, Jo and Hill, Geraldine B and Roake, Justin and Merriman, Tony R and Oszkinis, Grzegorz and Galora, Silvia and Saracini, Claudia and Abbate, Rosanna and Pulli, Raffaele and Pratesi, Carlo and Saratzis, Athanasios and Verissimo, Ana R and Bumpstead, Suzannah and Badger, Stephen A and Clough, Rachel E and Cockerill, Gillian and Hafez, Hany and Scott, D. Julian A and Futers, T. Simon and Romaine, Simon P. R and Bridge, Katherine and Griffin, Kathryn J and Bailey, Marc A and Smith, Alberto and Thompson, Matthew and van Bockxmeer, Frank M and Matthiasson, Stefan E and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Blankensteijn, Jan D and Teijink, Joep A. W and Wijmenga, Cisca and de Graaf, Jacqueline and Kiemeney, Lambertus A and Lindholt, Jes S and Hughes, Anne E and Bradley, Declan T and Stirrups, Kathleen and Golledge, Jonathan and Norman, Paul E and Powell, Janet T and Humphries, Steve E and Hamby, Stephen E and Goodall, Alison H and Nelson, Christopher P and Sakalihasan, Natzi and Courtois, Auey and Ferrell, Robert E and Eriksson, Per and Folkersen, Lasse and Franco-Cereceda, Anders and Eicher, John D and Johnson, Anew D and Betsholtz, Christer and Ruusalepp, Arno and Franzen, Oscar and Schadt, Eric and Bjorkegren, Johan L. M and ...
Circulation research, ISSN 0009-7330, 01/2017, Volume 120, Issue 2, pp. 341 - 353
Rationale: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci... 
Journal Article
by Jones, Gregory T and Tromp, Gerard and Kuivaniemi, Helena and Gretarsdottir, Solveig and Baas, Annette F and Giusti, Betti and Strauss, Ewa and Van't Hof, Femke N G and Webb, Thomas R and Erdman, Robert and Ritchie, Marylyn D and Elmore, James R and Verma, Anurag and Pendergrass, Sarah and Kullo, Iftikhar J and Ye, Zi and Peissig, Peggy L and Gottesman, Omri and Verma, Shefali S and Malinowski, Jennifer and Rasmussen-Torvik, Laura J and Borthwick, Kenneth M and Smelser, Diane T and Crosslin, David R and de Anade, Mariza and Ryer, Evan J and McCarty, Catherine A and Böttinger, Erwin P and Pacheco, Jennifer A and Crawford, Dana C and Carrell, David S and Gerhard, Glenn S and Franklin, David P and Carey, David J and Phillips, Victoria L and Williams, Michael J A and Wei, Wenhua and Blair, Ross and Hill, Anew A and Vasudevan, Thodor M and Lewis, David R and Thomson, Ian A and Krysa, Jo and Hill, Geraldine B and Roake, Justin and Merriman, Tony R and Oszkinis, Grzegorz and Galora, Silvia and Saracini, Claudia and Abbate, Rosanna and Pulli, Raffaele and Pratesi, Carlo and Saratzis, Athanasios and Verissimo, Ana R and Bumpstead, Suzannah and Badger, Stephen A and Clough, Rachel E and Cockerill, Gillian and Hafez, Hany and Scott, D Julian A and Futers, T Simon and Romaine, Simon P R and Bridge, Katherine and Griffin, Kathryn J and Bailey, Marc A and Smith, Alberto and Thompson, Matthew M and van Bockxmeer, Frank M and Matthiasson, Stefan E and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Blankensteijn, Jan D and Teijink, Joep A W and Wijmenga, Cisca and de Graaf, Jacqueline and Kiemeney, Lambertus A and Lindholt, Jes S and Hughes, Anne and Bradley, Declan T and Stirrups, Kathleen and Golledge, Jonathan and Norman, Paul E and Powell, Janet T and Humphries, Steve E and Hamby, Stephen E and Goodall, Alison H and Nelson, Christopher P and Sakalihasan, Natzi and Courtois, Auey and Ferrell, Robert E and Eriksson, Per and Folkersen, Lasse and Franco-Cereceda, Anders and Eicher, John D and Johnson, Anew D and Betsholtz, Christer and Ruusalepp, Arno and Franzén, Oscar and Schadt, Eric E and Björkegren, Johan L M and ...
Circulation Research, ISSN 0009-7330, 01/2017, Volume 120, Issue 2, p. 341
RATIONALE: Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci... 
Journal Article
Bone, ISSN 8756-3282, 05/2008, Volume 42, Issue 5, p. 81
Journal Article
by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and The EPIC-InterAct Consortium and CHD Exome+ Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Journal Article
by Turcot, Valérie and Lu, Yingchang and Highland, Heather M and Schurmann, Claudia and Justice, Anne E and Fine, Rebecca S and Bradfield, Jonathan P and Esko, Tõnu and Giri, Ayush and Graff, Mariaelisa and Guo, Xiuqing and Hendricks, Audrey E and Karaderi, Tugce and Lempradl, Adelheid and Locke, Adam E and Mahajan, Anubha and Marouli, Eirini and Sivapalaratnam, Suthesh and Young, Kristin L and Alfred, Tamuno and Feitosa, Mary F and Masca, Nicholas G. D and Manning, Alisa K and Medina-Gomez, Carolina and Mudgal, Poorva and Ng, Maggie C. Y and Reiner, Alex P and Vedantam, Sailaja and Willems, Sara M and Winkler, Thomas W and Abecasis, Gonçalo and Aben, Katja K and Alam, Dewan S and Alharthi, Sameer E and Allison, Matthew and Amouyel, Philippe and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Bang, Lia E and Barroso, Inês and Bastarache, Lisa and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boehnke, Michael and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Brumat, Marco and Burt, Amber A and Butterworth, Adam S and Campbell, Peter T and Cappellani, Stefania and Carey, David J and Catamo, Eulalia and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der I and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Cocca, Massimiliano and Cook, James P and Corley, Janie and Corominas Galbany, Jordi and Cox, Amanda J and Crosslin, David S and Cuellar-Partida, Gabriel and D'Eustacchio, Angela and Danesh, John and Davies, Gail and Bakker, Paul I. W and Groot, Mark C. H and Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and Heijer, Martin and Hollander, Anneke I and Ruijter, Hester M and Dennis, Joe G and Denny, Josh C and Angelantonio, Emanuele and Drenos, Fotios and Du, Mengmeng and Dubé, Marie-Pierre and Dunning, Alison M and Easton, Douglas F and Edwards, Todd L and ... and Chd Exome Consortium and EPIC InterAct Consortium and Global Lipids Genetic Consortium and GoT2D Genes Consortium and MAGIC Investigators and Understanding Soc Sci Grp and ReproGen Consortium and Interval Study and Epic-Cvd Consortium and ExomeBP Consortium and T2D-Genes Consortium and INTERVAL Study and EPIC-CVD Consortium and EPIC InterAct Consortium and CHD Exome+ Consortium and Understanding Society Scientific Group and The MAGIC Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 01/2018, Volume 50, Issue 1, pp. 26 - 35
Journal Article
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article