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F1000Research, ISSN 2046-1402, 2016, Volume 5, p. 137
A common pathological hallmark of age-related neurodegenerative diseases is the intracellular accumulation of protein aggregates such as α-synuclein in... 
Ubiquitin | Neurosciences | Immunoglobulins | Ubiquitin-specific proteinase | Neurodegenerative diseases | siRNA | Synuclein | Protein turnover | Proteins | Tau protein | Plasmids | Penicillin | Proteasomes | Intracellular | Age | Neurogenetics | Cognitive Neurology & Dementia | Protein Chemistry & Proteomics
Journal Article
Trends in Neurosciences, ISSN 0166-2236, 2005, Volume 28, Issue 4, pp. 182 - 187
Journal Article
The Journal of Physiology, ISSN 0022-3751, 12/2008, Volume 586, Issue 24, pp. 5885 - 5900
Journal Article
Journal Article
Journal of Visualized Experiments, ISSN 1940-087X, 2011, Issue 49
Brain injury, genetic manipulations, and pharmacological treatments can result in alterations of motor skills in mice. Fine motor coordination and balance can... 
Issue 49 | Neuroscience | Coordination | Mouse behavior | Balance beam test | Motor skills | balance beam test | mouse behavior | motor skills | MULTIDISCIPLINARY SCIENCES | coordination | Rotarod Performance Test | Animals | Motor Skills - physiology | Mice, Inbred C57BL | Female | Male | Mice | Postural Balance - physiology | Psychomotor Performance - physiology | Task Performance and Analysis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2015, Volume 290, Issue 8, pp. 4908 - 4927
synGAP is a neuron-specific Ras and Rap GTPase-activating protein (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the... 
NMDA RECEPTOR | DOMAIN | STIMULATION | INHIBITION | CALPAIN | CLONING | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATIONS | HIPPOCAMPAL-NEURONS | PLASTICITY | Oncogene Proteins - genetics | ras Proteins - genetics | Phosphorylation | ras GTPase-Activating Proteins - chemistry | rap1 GTP-Binding Proteins - chemistry | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | ras Proteins - metabolism | Neurons - cytology | GTPase-Activating Proteins - metabolism | Receptors, N-Methyl-D-Aspartate - genetics | Cyclin-Dependent Kinase 5 - chemistry | Cyclin-Dependent Kinase 5 - genetics | ras GTPase-Activating Proteins - genetics | Receptors, N-Methyl-D-Aspartate - chemistry | ras Proteins - chemistry | Proto-Oncogene Proteins p21(ras) - chemistry | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | rap1 GTP-Binding Proteins - metabolism | ras GTPase-Activating Proteins - metabolism | Oncogene Proteins - chemistry | Cells, Cultured | Oncogene Proteins - metabolism | Rats | Synapses - enzymology | GTPase-Activating Proteins - chemistry | Cyclin-Dependent Kinase 5 - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Animals | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - chemistry | Neurons - enzymology | GTPase-Activating Proteins - genetics | rap1 GTP-Binding Proteins - genetics | rap GTP-Binding Proteins | Ras Protein | Ras-related Protein 1 (Rap1) | Postsynaptic Density | Ca2 | Synaptic Plasticity | Small GTPase | Neurobiology | Mass Spectrometry (MS) | Cyclin-dependent Kinase 5 (CDK5) | Protein Kinase | Calmodulin-dependent Protein Kinase II (CaMKII) | Synaptic GTPase-activating Protein (synGAP)
Journal Article
The Journal of Physiology, ISSN 0022-3751, 12/2008, Volume 586, Issue 24, pp. 5885 - 5900
Journal Article
Trends in Neurosciences, ISSN 0166-2236, 04/2005, Volume 28, Issue 4, p. 182
  Many forms of mental retardation and cognitive disability are associated with abnormalities in dendritic spine morphology. Visualization of spines using... 
Proteins | Signal transduction | Spine | Neurons | Neurological disorders
Journal Article
Autophagy, ISSN 1554-8627, 04/2016, Volume 12, Issue 4, pp. 713 - 726
Autophagy is the primary process for recycling cellular constituents through lysosomal degradation. In addition to nonselective autophagic engulfment of... 
CK1α. CSNK1A1 | pulse-chase | RNAi | siRNA screen | Autophagy | p62 | SQSTM1 | MTOR | CK1 alpha | CSNK1A1 | CELL BIOLOGY | Green Fluorescent Proteins - metabolism | Reproducibility of Results | Animals | Cell Survival | Humans | Cell Line, Tumor | Imaging, Three-Dimensional | Gene Knockdown Techniques | High-Throughput Screening Assays - methods | RNA, Small Interfering - metabolism
Journal Article
F1000Research, ISSN 2046-1402, 2016, Volume 5, p. 137
A common pathological hallmark of age-related neurodegenerative diseases is the intracellular accumulation of protein aggregates such as α-synuclein in... 
Neurogenetics | Cognitive Neurology & Dementia | Protein Chemistry & Proteomics
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2011, Volume 31, Issue 45, pp. 16194 - 16207
Densin is an abundant scaffold protein in the postsynaptic density (PSD) that forms a high-affinity complex with alpha CaMKII and alpha-actinin. To assess the... 
NR2B SUBUNIT | IN-VIVO | DEPENDENT PROTEIN-KINASE | AUTISM SPECTRUM DISORDERS | D-ASPARTATE RECEPTOR | SYNAPTIC PLASTICITY | HIPPOCAMPAL-NEURONS | HUNTINGTONS-DISEASE | REPEAT PROTEIN | NEUROSCIENCES | MOUSE MODELS | Mental Disorders - pathology | Muscle Strength - genetics | Embryo, Mammalian | Endophenotypes | Male | Dendritic Spines - metabolism | Green Fluorescent Proteins - genetics | Memory, Short-Term - physiology | Glial Fibrillary Acidic Protein - metabolism | Body Weight - genetics | Recognition (Psychology) - physiology | Mental Disorders - genetics | Time Factors | Statistics, Nonparametric | Receptors, AMPA - genetics | Disease Models, Animal | GABA-A Receptor Antagonists - pharmacology | Inhibition (Psychology) | Membrane Potentials - drug effects | Behavior, Animal - physiology | Genotype | Bicuculline - pharmacology | Mutation - genetics | GABA Antagonists - pharmacology | Mice, Knockout | Patch-Clamp Techniques | Glycine - pharmacology | Mice | Aggression - physiology | Long-Term Synaptic Depression - genetics | Membrane Potentials - genetics | Actins - metabolism | Neurons - cytology | Receptors, Kainic Acid - genetics | Psychomotor Performance - physiology | Exploratory Behavior - physiology | Female | Post-Synaptic Density - metabolism | Neurons - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Cells, Cultured | Long-Term Potentiation - genetics | Hippocampus - cytology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Motor Activity - genetics | Receptors, Kainic Acid - metabolism | Rotarod Performance Test | Animals | Picrotoxin - pharmacology | In Vitro Techniques | Sialoglycoproteins - deficiency
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 11/2002, Volume 22, Issue 22, pp. 9721 - 9732
Journal Article
Journal Article
EMBO reports, ISSN 1469-221X, 06/2010, Volume 11, Issue 6, pp. 473 - 478
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2000, Volume 39, Issue 4, pp. 611 - 620
Cell lines are commonly used for studying recombinant heterooligomeric ion channels with defined subunit composition. Such studies often ignore the... 
WSS-1 cells | GABA(A) receptors | HEK293 cells | NB41A3 cells | RT-PCR | Loreclezole | Benzodiazepines
Journal Article