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by Morrissy, A. Sorana and Garzia, Livia and Shih, David J. H and Zuyderduyn, Scott and Huang, Xi and Skowron, Patryk and Remke, Marc and Cavalli, Florence M. G and Ramaswamy, Vijay and Lindsay, Patricia E and Jelveh, Salomeh and Donovan, Laura K and Wang, Xin and Luu, Betty and Zayne, Kory and Li, Yisu and Mayoh, Chelsea and Thiessen, Nina and Mercier, Eloi and Mungall, Karen L and Ma, Yusanne and Tse, Kane and Zeng, Thomas and Shumansky, Karey and Roth, Andrew J. L and Shah, Sohrab and Farooq, Hamza and Kijima, Noriyuki and Holgado, Borja L and Lee, John J. Y and Matan-Lithwick, Stuart and Liu, Jessica and Mack, Stephen C and Manno, Alex and Michealraj, K. A and Nor, Carolina and Peacock, John and Qin, Lei and Reimand, Juri and Rolider, Adi and Thompson, Yuan Y and Wu, Xiaochong and Pugh, Trevor and Ally, Adrian and Bilenky, Mikhail and Butterfield, Yaron S. N and Carlsen, Rebecca and Cheng, Young and Chuah, Eric and Corbett, Richard D and Dhalla, Noreen and He, An and Lee, Darlene and Li, Haiyan I and Long, William and Mayo, Michael and Plettner, Patrick and Qian, Jenny Q and Schein, Jacqueline E and Tam, Angela and Wong, Tina and Birol, Inanc and Zhao, Yongjun and Faria, Claudia C and Pimentel, José and Nunes, Sofia and Shalaby, Tarek and Grotzer, Michael and Pollack, Ian F and Hamilton, Ronald L and Li, Xiao-Nan and Bendel, Anne E and Fults, Daniel W and Walter, Andrew W and Kumabe, Toshihiro and Tominaga, Teiji and Collins, V. Peter and Cho, Yoon-Jae and Hoffman, Caitlin and Lyden, David and Wisoff, Jeffrey H and Garvin, James H and Stearns, Duncan S and Massimi, Luca and Schüller, Ulrich and Sterba, Jaroslav and Zitterbart, Karel and Puget, Stephanie and Ayrault, Olivier and Dunn, Sandra E and Tirapelli, Daniela P. C and Carlotti, Carlos G and Wheeler, Helen and Hallahan, Andrew R and Ingram, Wendy and MacDonald, Tobey J and Olson, Jeffrey J and Van Meir, Erwin G and Lee, Ji-Yeoun and Wang, Kyu-Chang and ...
Nature (London), ISSN 1476-4687, 2016, Volume 529, Issue 7586, pp. 351 - 357
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related... 
HETEROGENEITY | CANCER EVOLUTION | CELLS | IMPACT | MULTIDISCIPLINARY SCIENCES | SUBGROUP MEDULLOBLASTOMA | DYNAMICS | MUTATIONS | SEQUENCING DATA | LYMPHOBLASTIC-LEUKEMIA | GENOME | Clone Cells - drug effects | Humans | Male | Medulloblastoma - therapy | Radiotherapy, Image-Guided | Selection, Genetic - drug effects | Drosophila melanogaster - genetics | Neoplasm Recurrence, Local - pathology | Medulloblastoma - radiotherapy | DNA Mutational Analysis | Medulloblastoma - pathology | Female | Medulloblastoma - surgery | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Molecular Targeted Therapy - methods | Disease Models, Animal | Signal Transduction | Neoplasm Recurrence, Local - therapy | Drosophila melanogaster - cytology | Cerebellar Neoplasms - genetics | Clone Cells - metabolism | Genome, Human - genetics | Xenograft Model Antitumor Assays | Animals | Clone Cells - pathology | Craniospinal Irradiation | Neoplasm Recurrence, Local - genetics | Mice | Cerebellar Neoplasms - therapy | Cerebellar Neoplasms - surgery | Cerebellar Neoplasms - radiotherapy | Clonal selection theory | Care and treatment | Medulloblastoma | Oncology, Experimental | Genetic aspects | Research | Cancer | Genes | Cloning | Clinical trials | Cytotoxicity | Genomes | Radiation therapy | Metastasis | Cancer therapies | Rodents | Medical prognosis | Mutation | Tumors | Index Medicus
Journal Article
by Morrissy, A Sorana and Cavalli, Florence M G and Remke, Marc and Ramaswamy, Vijay and Shih, David J H and Holgado, Borja L and Farooq, Hamza and Donovan, Laura K and Garzia, Livia and Agnihotri, Sameer and Kiehna, Erin N and Mercier, Eloi and Mayoh, Chelsea and Papillon-Cavanagh, Simon and Nikbakht, Hamid and Gayden, Tenzin and Torchia, Jonathon and Picard, Daniel and Merino, Diana M and Vladoiu, Maria and Luu, Betty and Wu, Xiaochong and Daniels, Craig and Horswell, Stuart and Thompson, Yuan Yao and Hovestadt, Volker and Northcott, Paul A and Jones, David T W and Peacock, John and Wang, Xin and Mack, Stephen C and Reimand, Jüri and Albrecht, Steffen and Fontebasso, Adam M and Thiessen, Nina and Li, Yisu and Schein, Jacqueline E and Lee, Darlene and Carlsen, Rebecca and Mayo, Michael and Tse, Kane and Tam, Angela and Dhalla, Noreen and Ally, Adrian and Chuah, Eric and Cheng, Young and Plettner, Patrick and Li, Haiyan I and Corbett, Richard D and Wong, Tina and Long, William and Loukides, James and Buczkowicz, Pawel and Hawkins, Cynthia E and Tabori, Uri and Rood, Brian R and Myseros, John S and Packer, Roger J and Korshunov, Andrey and Lichter, Peter and Kool, Marcel and Pfister, Stefan M and Schüller, Ulrich and Dirks, Peter and Huang, Annie and Bouffet, Eric and Rutka, James T and Bader, Gary D and Swanton, Charles and Ma, Yusanne and Moore, Richard A and Mungall, Andrew J and Majewski, Jacek and Jones, Steven J M and Das, Sunit and Malkin, David and Jabado, Nada and Marra, Marco A and Taylor, Michael D
Nature genetics, ISSN 1546-1718, 2017, Volume 49, Issue 5, pp. 780 - 788
...]; Nina Thiessen [11]; Yisu Li [11]; Jacqueline E Schein [11]; Darlene Lee [11]; Rebecca Carlsen [11]; Michael Mayo [11]; Kane Tse [11]; Angela Tam [11]; Noreen... 
IN-VITRO | EVOLUTION | SOLID TUMORS | SUBTYPES | INTRATUMOR HETEROGENEITY | GROWTH | GENETICS & HEREDITY | EXPRESSION | RENAL-CELL CARCINOMA | T-CELLS | LYMPHOCYTES | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Transcriptome | Child, Preschool | Male | INDEL Mutation | DNA Copy Number Variations | Medulloblastoma - pathology | Aged, 80 and over | Adult | Female | Cerebellar Neoplasms - pathology | Medulloblastoma - genetics | Child | Principal Component Analysis | Genome-Wide Association Study | Gene Expression Profiling - methods | Cerebellar Neoplasms - genetics | Reverse Transcriptase Polymerase Chain Reaction | Genetic Heterogeneity | Aged | Polymorphism, Single Nucleotide | Mutation | Cluster Analysis | Brain | Gene mutations | Biopsy | Medulloblastoma | Genetic aspects | Diagnosis | Health aspects | Methods | Pediatrics | Laboratories | Neuropathology | Brain cancer | Colleges & universities | Oncology | Genomes | Biology | Neurosurgery | Consortia | Heterogeneity | Immunology | Renal cell carcinoma | Genetics | Research centers | Medical research | Hematology | Gene expression | Children & youth | Genetic markers | Hospitals | Glioma | Biomarkers | Tumors | Spatial heterogeneity | glioblastoma multiforme | renal cell carcinoma | gene expression profiling | medulloblastoma | whole exome sequencing
Journal Article
by Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chuah, Eric and Clarke, Amanda and Dhalla, Noreen and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Thiessen, Nina and Cheung, Dorothy and Wong, Tina and Brooks, Denise and Robertson, A. Gordon and Bowlby, Reanne and Mungall, Karen and Sadeghi, Sara and Xi, Liu and Covington, Kyle and Shinbrot, Eve and Wheeler, David A and Gibbs, Richard A and Donehower, Lawrence A and Wang, Linghua and Bowen, Jay and Gastier-Foster, Julie M and Gerken, Mark and Helsel, Carmen and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Wise, Lisa and Zmuda, Erik and Gabriel, Stacey B and Meyerson, Matthew and Cibulskis, Carrie and Murray, Bradley A and Shih, Juliann and Beroukhim, Rameen and Cherniack, Andrew D and Schumacher, Steven E and Saksena, Gordon and Pedamallu, Chandra Sekhar and Chin, Lynda and Getz, Gad and Noble, Michael and Zhang, Hailei and Heiman, David and Cho, Juok and Gehlenborg, Nils and Voet, Douglas and Lin, Pei and Frazer, Scott and Defreitas, Timothy and Meier, Sam and Lawrence, Michael and Kim, Jaegil and Creighton, Chad J and Muzny, Donna and Doddapaneni, HarshaVardhan and Hu, Jianhong and Wang, Min and Morton, Donna and Korchina, Viktoriya and Han, Yi and Dinh, Huyen and Lewis, Lora and Bellair, Michelle and Liu, Xiuping and Santibanez, Jireh and Glenn, Robert and Lee, Sandra and Hale, Walker and Parker, Joel S and Wilkerson, Matthew D and Hayes, D. Neil and Reynolds, Sheila M and Shmulevich, Ilya and Zhang, Wei and Liu, Yuexin and Iype, Lisa and Makhlouf, Hala and Torbenson, Michael S and Kakar, Sanjay and Yeh, Matthew M and Jain, Dhanpat and Kleiner, David E and Dhanasekaran, Renumathy and El-Serag, Hashem B and Yim, Sun Young and Weinstein, John N and Mishra, Lopa and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Cancer Genome Atlas Research Network. Electronic address: wheeler@bcm.edu
Cell (Cambridge), ISSN 0092-8674, 2017, Volume 169, Issue 7, pp. 1327 - 1341.e23
Journal Article
by Robertson, A. Gordon and Kim, Jaegil and Al-Ahmadie, Hikmat and Bellmunt, Joaquim and Guo, Guangwu and Cherniack, Andrew D and Hinoue, Toshinori and Laird, Peter W and Hoadley, Katherine A and Akbani, Rehan and Castro, Mauro A.A and Gibb, Ewan A and Kanchi, Rupa S and Gordenin, Dmitry A and Shukla, Sachet A and Sanchez-Vega, Francisco and Hansel, Donna E and Czerniak, Bogdan A and Reuter, Victor E and Su, Xiaoping and de Sa Carvalho, Benilton and Chagas, Vinicius S and Mungall, Karen L and Sadeghi, Sara and Pedamallu, Chandra Sekhar and Lu, Yiling and Klimczak, Leszek J and Zhang, Jiexin and Choo, Caleb and Ojesina, Akinyemi I and Bullman, Susan and Leraas, Kristen M and Lichtenberg, Tara M and Wu, Catherine J and Schultz, Nicholaus and Getz, Gad and Meyerson, Matthew and Mills, Gordon B and McConkey, David J and Weinstein, John N and Kwiatkowski, David J and Lerner, Seth P and Albert, Monique and Alexopoulou, Iakovina and Ally, Adrian and Antic, Tatjana and Aron, Manju and Balasundaram, Miruna and Bartlett, John and Baylin, Stephen B and Beaver, Allison and Birol, Inanc and Boice, Lori and Bootwalla, Moiz S and Bowen, Jay and Bowlby, Reanne and Brooks, Denise and Broom, Bradley M and Bshara, Wiam and Burks, Eric and Cárcano, Flavio M and Carlsen, Rebecca and Carvalho, Benilton S and Carvalho, Andre L and Castle, Eric P and Castro, Patricia and Catto, James W and Chesla, David W and Chuah, Eric and Chudamani, Sudha and Cortessis, Victoria K and Cottingham, Sandra L and Crain, Daniel and Curley, Erin and Daneshmand, Siamak and Demchok, John A and Dhalla, Noreen and Djaladat, Hooman and Eckman, John and Egea, Sophie C and Engel, Jay and Felau, Ina and Ferguson, Martin L and Gardner, Johanna and Gastier-Foster, Julie M and Gerken, Mark and Gomez-Fernandez, Carmen R and Harr, Jodi and Hartmann, Arndt and Herbert, Lynn M and Ho, Thai H and Holt, Robert A and Hutter, Carolyn M and Jones, Steven J.M and Jorda, Merce and Kahnoski, Richard J and Kasaian, Katayoon and Lai, Phillip H and Lane, Brian R and Liu, Jia and ... and TCGA Research Network and TCGA Res Network
Cell (Cambridge), ISSN 0092-8674, 2017, Volume 171, Issue 3, pp. 540 - 556.e25
Journal Article
by Raphael, Benjamin J and Hruban, Ralph H and Aguirre, Andrew J and Moffitt, Richard A and Yeh, Jen Jen and Stewart, Chip and Robertson, A. Gordon and Cherniack, Andrew D and Gupta, Manaswi and Getz, Gad and Gabriel, Stacey B and Meyerson, Matthew and Cibulskis, Carrie and Fei, Suzanne S and Hinoue, Toshinori and Shen, Hui and Laird, Peter W and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Akbani, Rehan and Loher, Phillipe and Londin, Eric R and Rigoutsos, Isidore and Telonis, Aristeidis G and Gibb, Ewan A and Goldenberg, Anna and Mezlini, Aziz M and Hoadley, Katherine A and Collisson, Eric and Lander, Eric and Murray, Bradley A and Hess, Julian and Rosenberg, Mara and Bergelson, Louis and Zhang, Hailei and Cho, Juok and Tiao, Grace and Kim, Jaegil and Livitz, Dimitri and Leshchiner, Ignaty and Reardon, Brendan and Van Allen, Eliezer and Kamburov, Atanas and Beroukhim, Rameen and Saksena, Gordon and Schumacher, Steven E and Noble, Michael S and Heiman, David I and Gehlenborg, Nils and Lawrence, Michael S and Adsay, Volkan and Petersen, Gloria and Klimstra, David and Bardeesy, Nabeel and Leiserson, Mark D.M and Bowlby, Reanne and Kasaian, Katayoon and Birol, Inanc and Mungall, Karen L and Sadeghi, Sara and Weinstein, John N and Spellman, Paul T and Liu, Yuexin and Amundadottir, Laufey T and Tepper, Joel and Singhi, Aatur D and Dhir, Rajiv and Paul, Drwiega and Smyrk, Thomas and Zhang, Lizhi and Kim, Paula and Bowen, Jay and Frick, Jessica and Gastier-Foster, Julie M and Gerken, Mark and Lau, Kevin and Leraas, Kristen M and Lichtenberg, Tara M and Ramirez, Nilsa C and Renkel, Jeremy and Sherman, Mark and Wise, Lisa and Yena, Peggy and Zmuda, Erik and Shih, Juliann and Ally, Adrian and Balasundaram, Miruna and Carlsen, Rebecca and Chu, Andy and Chuah, Eric and Clarke, Amanda and Dhalla, Noreen and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Ma, Yussanne and Marra, Marco A and Mayo, Michael and Moore, Richard A and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network. Electronic address: andrew_aguirre@dfci.harvard.edu and Cancer Genome Atlas Research Network
Cancer cell, ISSN 1535-6108, 2017, Volume 32, Issue 2, pp. 185 - 203.e13
Journal Article
by Brat, Daniel J and Verhaak, Roel G. W and Aldape, Kenneth D and Yung, W. K. Alfred and Salama, Sofie R and Cooper, Lee A. D and Rheinbay, Esther and Miller, C. Ryan and Vitucci, Mark and Morozova, Olena and Robertson, A. Gordon and Noushmehr, Houtan and Laird, Peter W and Cherniack, Andrew D and Akbani, Rehan and Huse, Jason T and Ciriello, Giovanni and Poisson, Laila M and Barnholtz-Sloan, Jill S and Berger, Mitchel S and Brennan, Cameron and Colen, Rivka R and Colman, Howard and Flanders, Adam E and Giannini, Caterina and Grifford, Mia and Iavarone, Antonio and Jain, Rajan and Joseph, Isaac and Kim, Jaegil and Kasaian, Katayoon and Mikkelsen, Tom and Murray, Bradley A and O'Neill, Brian Patrick and Pachter, Lior and Parsons, Donald W and Sougnez, Carrie and Sulman, Erik P and Vandenberg, Scott R and Van Meir, Erwin G and Von Deimling, Andreas and Zhang, Hailei and Crain, Daniel and Lau, Kevin and Mallery, David and Morris, Scott and Paulauskis, Joseph and Penny, Robert and Shelton, Troy and Sherman, Mark and Yena, Peggy and Black, Aaron and Bowen, Jay and Dicostanzo, Katie and Gastier-Foster, Julie and Leraas, Kristen M and Lichtenberg, Tara M and Pierson, Christopher R and Ramirez, Nilsa C and Taylor, Cynthia and Weaver, Stephanie and Wise, Lisa and Zmuda, Erik and Davidsen, Tanja and Demchok, John A and Eley, Greg and Ferguson, Martin L and Hutter, Carolyn M and Shaw, Kenna R. Mills and Ozenberger, Bradley A and Sheth, Margi and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean Claude and Ayala, Brenda and Baboud, Julien and Chudamani, Sudha and Jensen, Mark A and Liu, Jia and Pihl, Todd and Raman, Rohini and Wan, Yunhu and Wu, Ye and Ally, Adrian and Auman, J. Todd and Balasundaram, Miruna and Balu, Saianand and Baylin, Stephen B and Beroukhim, Rameen and Bootwalla, Moiz S and Bowlby, Reanne and Bristow, Christopher A and Brooks, Denise and Butterfield, Yaron and Carlsen, Rebecca and Carter, Scott and Chin, Lynda and Chu, Andy and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
The New England journal of medicine, ISSN 1533-4406, 2015, Volume 372, Issue 26, pp. 2481 - 2498
Journal Article