Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2010, Volume 107, Issue 18, pp. 8404 - 8409
A recently identified variant within the fat mass and obesity-associated (FTO) gene is carried by 46% of Western Europeans and is associated with an ∼1.2 kg...
Neuroimaging | Body mass index | Obesity | Frontal lobe | Alleles | Medical genetics | Alzheimers disease | Older adults | White matter | Genotypes | Tensor-based morphometry | Alzheimer's disease neuroimaging initiative | Brain structure | tensor-based morphometry | ATROPHY | body mass index | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | FUSED TOES FT | MILD COGNITIVE IMPAIRMENT | ADULT OBESITY | Alzheimer's Disease Neuroimaging Initiative | BODY-MASS INDEX | PHYSICAL-ACTIVITY | MATTER HYPERINTENSITY VOLUME | brain structure | obesity | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Brain - anatomy & histology | Humans | Risk Factors | Organ Size | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | Obesity - genetics | Brain - metabolism | Proteins - genetics | Magnetic Resonance Imaging | Aged | Imaging, Three-Dimensional | Allelomorphism | Brain | Physiological aspects | Genetic aspects | Research | Health aspects | Biological Sciences
Neuroimaging | Body mass index | Obesity | Frontal lobe | Alleles | Medical genetics | Alzheimers disease | Older adults | White matter | Genotypes | Tensor-based morphometry | Alzheimer's disease neuroimaging initiative | Brain structure | tensor-based morphometry | ATROPHY | body mass index | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | FUSED TOES FT | MILD COGNITIVE IMPAIRMENT | ADULT OBESITY | Alzheimer's Disease Neuroimaging Initiative | BODY-MASS INDEX | PHYSICAL-ACTIVITY | MATTER HYPERINTENSITY VOLUME | brain structure | obesity | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Brain - anatomy & histology | Humans | Risk Factors | Organ Size | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | Obesity - genetics | Brain - metabolism | Proteins - genetics | Magnetic Resonance Imaging | Aged | Imaging, Three-Dimensional | Allelomorphism | Brain | Physiological aspects | Genetic aspects | Research | Health aspects | Biological Sciences
Journal Article
Development (Cambridge), ISSN 0950-1991, 10/2015, Volume 142, Issue 20, pp. 3519 - 3528
Current understanding infers a neural crest origin of thyroid C cells, the major source of calcitonin in mammals and ancestors to neuroendocrine thyroid...
Foxa1 | Neuroendocrine | Neural crest | Endoderm | Foxa2 | Medullary thyroid cancer | ULTIMOBRANCHIAL BODY | MOUSE | DEVELOPMENTAL BIOLOGY | TUMORS | ORGANOGENESIS | CALCITONIN-PRODUCING CELLS | TO-MESENCHYMAL TRANSITION | MEDULLARY | EXPRESSION | CARCINOMA | Intestinal Mucosa - metabolism | Calcium - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Carcinoma, Medullary - metabolism | Male | Gene Expression Profiling | Stem Cells - cytology | Gene Expression Regulation, Developmental | Epithelial-Mesenchymal Transition | Female | Cell Differentiation | Thyroid Gland - embryology | Thyroid Gland - cytology | Calcitonin - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Neural Crest - cytology | Mice, Inbred C57BL | Endoderm - metabolism | Hepatocyte Nuclear Factor 3-alpha - metabolism | Cell Lineage | Animals | Mice | Thyroid Neoplasms - metabolism | Surgery | Kirurgi
Foxa1 | Neuroendocrine | Neural crest | Endoderm | Foxa2 | Medullary thyroid cancer | ULTIMOBRANCHIAL BODY | MOUSE | DEVELOPMENTAL BIOLOGY | TUMORS | ORGANOGENESIS | CALCITONIN-PRODUCING CELLS | TO-MESENCHYMAL TRANSITION | MEDULLARY | EXPRESSION | CARCINOMA | Intestinal Mucosa - metabolism | Calcium - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Carcinoma, Medullary - metabolism | Male | Gene Expression Profiling | Stem Cells - cytology | Gene Expression Regulation, Developmental | Epithelial-Mesenchymal Transition | Female | Cell Differentiation | Thyroid Gland - embryology | Thyroid Gland - cytology | Calcitonin - metabolism | Hepatocyte Nuclear Factor 3-beta - metabolism | Neural Crest - cytology | Mice, Inbred C57BL | Endoderm - metabolism | Hepatocyte Nuclear Factor 3-alpha - metabolism | Cell Lineage | Animals | Mice | Thyroid Neoplasms - metabolism | Surgery | Kirurgi
Journal Article
BMC Psychiatry, ISSN 1471-244X, 01/2017, Volume 17, Issue 1, pp. 5 - Article 5
Background: A substantial amount of refugees (10-30%) suffer from Post-Traumatic Stress Disorder (PTSD). In Denmark there are different facilities specialised...
PTSD | Complex PTSD | Refugees | Psychotic symptoms | PTSD-SP | RISK-FACTORS | METAANALYSIS | PSYCHIATRY | MENTAL-HEALTH | PREVALENCE | TORTURED REFUGEES | COMORBIDITY | SAMPLE | PREDICTORS | QUALITY-OF-LIFE | ASSOCIATION | Psychotic Disorders - diagnosis | Hallucinations - diagnosis | Refugees - psychology | Humans | Middle Aged | Psychotic Disorders - psychology | Refugees - statistics & numerical data | Male | Stress Disorders, Post-Traumatic - psychology | Stress, Psychological - diagnosis | Young Adult | Hallucinations - psychology | Stress Disorders, Post-Traumatic - diagnosis | Delusions - diagnosis | Denmark | Adult | Female | Retrospective Studies | Personality Disorders - diagnosis | Mental Health - statistics & numerical data | Care and treatment | Analysis | Post-traumatic stress disorder | Diagnosis | Health aspects | Psychiatric services | In-Process
PTSD | Complex PTSD | Refugees | Psychotic symptoms | PTSD-SP | RISK-FACTORS | METAANALYSIS | PSYCHIATRY | MENTAL-HEALTH | PREVALENCE | TORTURED REFUGEES | COMORBIDITY | SAMPLE | PREDICTORS | QUALITY-OF-LIFE | ASSOCIATION | Psychotic Disorders - diagnosis | Hallucinations - diagnosis | Refugees - psychology | Humans | Middle Aged | Psychotic Disorders - psychology | Refugees - statistics & numerical data | Male | Stress Disorders, Post-Traumatic - psychology | Stress, Psychological - diagnosis | Young Adult | Hallucinations - psychology | Stress Disorders, Post-Traumatic - diagnosis | Delusions - diagnosis | Denmark | Adult | Female | Retrospective Studies | Personality Disorders - diagnosis | Mental Health - statistics & numerical data | Care and treatment | Analysis | Post-traumatic stress disorder | Diagnosis | Health aspects | Psychiatric services | In-Process
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2017, Volume 12, Issue 3, pp. e0169490 - Article e0169490
markdownabstractBackground: Traumatic brain injury (TBI) is a complex disorder that is traditionally stratified based on clinical signs and symptoms. Recent...
PROTEIN | COMMON DATA ELEMENTS | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | POLYMORPHISM | COMT | CLINICAL KNOWLEDGE | TRANSFORMING RESEARCH | PREDICTION | Humans | Middle Aged | Brain Injuries, Traumatic - diagnostic imaging | Protein-Serine-Threonine Kinases - genetics | Male | Stress Disorders, Post-Traumatic - physiopathology | Catechol O-Methyltransferase - genetics | Brain Injuries, Traumatic - genetics | Machine Learning | Receptors, Dopamine D2 - genetics | Brain Injuries, Traumatic - physiopathology | Stress Disorders, Post-Traumatic - diagnosis | Biomarkers | Adult | Female | Polymorphism, Single Nucleotide | Stress Disorders, Post-Traumatic - genetics | Brain Injuries, Traumatic - diagnosis | Poly (ADP-Ribose) Polymerase-1 - genetics | Stress Disorders, Post-Traumatic - diagnostic imaging | Brain | Usage | Care and treatment | Research | Topology | Diagnosis | Biological markers | Algebraic topology | Genetic polymorphisms | Injuries | Learning commons | Neuroimaging | Neurosciences | Traumatic brain injury | Mental disorders | DNA damage | Innovations | Clinical trials | Population studies | Statistical methods | Posttraumatic stress disorder | Neurosurgery | Population genetics | Subgroups | Head injuries | Data recovery | Surgery | Post-traumatic stress disorder | Neostriatum | Genetics | Dopamine D2 receptors | Injury analysis | Deoxyribonucleic acid--DNA | Medical research | Signs and symptoms | Data analysis | Dopamine | Statistical analysis | Medical imaging | Data processing | Statistical tests | Patients | Learning algorithms | Poly(ADP-ribose) Polymerase 1 | Population (statistical) | Post traumatic stress disorder | Brain research | Hospitals | Molecular modelling | Machine learning | Spinal cord injuries | Diagnostic systems | Traumatic Brain Injury | Clinical Trial | Head Injuries | Americans | Predisposition | Brain Imaging | Adults | Genetic Markers | Emergency Room Patients | PTSD (DSM-IV) | Statistical Analysis | Deoxyribonucleic acid | DNA
PROTEIN | COMMON DATA ELEMENTS | MULTIDISCIPLINARY SCIENCES | CLASSIFICATION | POLYMORPHISM | COMT | CLINICAL KNOWLEDGE | TRANSFORMING RESEARCH | PREDICTION | Humans | Middle Aged | Brain Injuries, Traumatic - diagnostic imaging | Protein-Serine-Threonine Kinases - genetics | Male | Stress Disorders, Post-Traumatic - physiopathology | Catechol O-Methyltransferase - genetics | Brain Injuries, Traumatic - genetics | Machine Learning | Receptors, Dopamine D2 - genetics | Brain Injuries, Traumatic - physiopathology | Stress Disorders, Post-Traumatic - diagnosis | Biomarkers | Adult | Female | Polymorphism, Single Nucleotide | Stress Disorders, Post-Traumatic - genetics | Brain Injuries, Traumatic - diagnosis | Poly (ADP-Ribose) Polymerase-1 - genetics | Stress Disorders, Post-Traumatic - diagnostic imaging | Brain | Usage | Care and treatment | Research | Topology | Diagnosis | Biological markers | Algebraic topology | Genetic polymorphisms | Injuries | Learning commons | Neuroimaging | Neurosciences | Traumatic brain injury | Mental disorders | DNA damage | Innovations | Clinical trials | Population studies | Statistical methods | Posttraumatic stress disorder | Neurosurgery | Population genetics | Subgroups | Head injuries | Data recovery | Surgery | Post-traumatic stress disorder | Neostriatum | Genetics | Dopamine D2 receptors | Injury analysis | Deoxyribonucleic acid--DNA | Medical research | Signs and symptoms | Data analysis | Dopamine | Statistical analysis | Medical imaging | Data processing | Statistical tests | Patients | Learning algorithms | Poly(ADP-ribose) Polymerase 1 | Population (statistical) | Post traumatic stress disorder | Brain research | Hospitals | Molecular modelling | Machine learning | Spinal cord injuries | Diagnostic systems | Traumatic Brain Injury | Clinical Trial | Head Injuries | Americans | Predisposition | Brain Imaging | Adults | Genetic Markers | Emergency Room Patients | PTSD (DSM-IV) | Statistical Analysis | Deoxyribonucleic acid | DNA
Journal Article
Psychiatric Services, ISSN 1075-2730, 03/2019, Volume 70, Issue 3, pp. 250 - 253
A myriad of cultural and language-related factors can affect the communication between clinicians, interpreters, and patients. Misunderstandings can lead to...
HEALTH POLICY & SERVICES | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | QUALITY | PSYCHIATRY | CARE
HEALTH POLICY & SERVICES | IMPACT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | QUALITY | PSYCHIATRY | CARE
Journal Article
The Canadian Journal of Psychiatry, ISSN 0706-7437, 1/2019, Volume 64, Issue 1, pp. 39 - 46
Objective: The Hamilton Depression Rating Scale (HDRS) is considered the gold standard measure of depression. The factor structure of the HDRS is generally...
Hamilton Depression Rating Scale | depression | factor structure | cross-cultural | PSYCHIATRY | PERFORMANCE | VERSION | DISORDERS | RELIABILITY | VALIDITY | Original Research
Hamilton Depression Rating Scale | depression | factor structure | cross-cultural | PSYCHIATRY | PERFORMANCE | VERSION | DISORDERS | RELIABILITY | VALIDITY | Original Research
Journal Article
Journal of Nervous and Mental Disease, ISSN 0022-3018, 2014, Volume 202, Issue 9, pp. 630 - 637
Journal Article
Ugeskrift for Laeger, ISSN 0041-5782, 2016, Volume 178, Issue 18, pp. 1716 - 1720
Journal Article
Nature Communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, p. 8581
Data-driven discovery in complex neurological disorders has potential to extract meaningful syndromic knowledge from large, heterogeneous data sets to enhance...
RECOVERY | MANAGEMENT | BIG DATA | LOCOMOTOR | MULTIDISCIPLINARY SCIENCES | CONSEQUENCES | MECHANISMS | RATING-SCALE | TRANSLATION | SEVERITY | CELL-DEATH | Computational Biology - methods | Data Interpretation, Statistical | Animals | Spinal Cord Injuries | Brain Injuries | Rats | Disease Models, Animal
RECOVERY | MANAGEMENT | BIG DATA | LOCOMOTOR | MULTIDISCIPLINARY SCIENCES | CONSEQUENCES | MECHANISMS | RATING-SCALE | TRANSLATION | SEVERITY | CELL-DEATH | Computational Biology - methods | Data Interpretation, Statistical | Animals | Spinal Cord Injuries | Brain Injuries | Rats | Disease Models, Animal
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 11/2016, Volume 75, Issue 11, pp. 2029 - 2036
ObjectivesIncreasing evidence suggests an epigenetic contribution to the pathogenesis of autoimmune diseases, including primary Sjögren's Syndrome (pSS). The...
Autoimmunity | Gene Polymorphism | B cells | Sjøgren's Syndrome | SYSTEM | PATHOGENESIS | NAIVE CD4+T CELLS | ACTIVATION | LUPUS | RNA | INFLAMMATION | LYMPHOMA | RHEUMATOLOGY | MICRORNA EXPRESSION | ASSOCIATION | Gene Expression | Genome-Wide Association Study | Sjogren's Syndrome - pathology | Cytoskeletal Proteins - genetics | Epigenesis, Genetic | Humans | Middle Aged | Male | Antigens, CD19 - genetics | Case-Control Studies | 2',5'-Oligoadenylate Synthetase - genetics | DNA Methylation | Poly(ADP-ribose) Polymerases - genetics | Salivary Glands, Minor - pathology | Sjogren's Syndrome - blood | Adult | Female | Aged | Interferons - genetics | Myxovirus Resistance Proteins - genetics | Neoplasm Proteins - genetics | Sjogren's Syndrome - genetics | Antigens - genetics | Sjogren's syndrome | Care and treatment | Usage | Genome-wide association studies | Diagnosis | Methylation | Patients | Health aspects | Basic and Translational Research | 1506 | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
Autoimmunity | Gene Polymorphism | B cells | Sjøgren's Syndrome | SYSTEM | PATHOGENESIS | NAIVE CD4+T CELLS | ACTIVATION | LUPUS | RNA | INFLAMMATION | LYMPHOMA | RHEUMATOLOGY | MICRORNA EXPRESSION | ASSOCIATION | Gene Expression | Genome-Wide Association Study | Sjogren's Syndrome - pathology | Cytoskeletal Proteins - genetics | Epigenesis, Genetic | Humans | Middle Aged | Male | Antigens, CD19 - genetics | Case-Control Studies | 2',5'-Oligoadenylate Synthetase - genetics | DNA Methylation | Poly(ADP-ribose) Polymerases - genetics | Salivary Glands, Minor - pathology | Sjogren's Syndrome - blood | Adult | Female | Aged | Interferons - genetics | Myxovirus Resistance Proteins - genetics | Neoplasm Proteins - genetics | Sjogren's Syndrome - genetics | Antigens - genetics | Sjogren's syndrome | Care and treatment | Usage | Genome-wide association studies | Diagnosis | Methylation | Patients | Health aspects | Basic and Translational Research | 1506 | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
Journal Article
Psychological Medicine, ISSN 0033-2917, 03/2019, Volume 49, Issue 4, pp. 581 - 589
Background Impairments in mechanisms underlying early information processing have been reported in posttraumatic stress disorder (PTSD); however, findings in...
sensory gating | refugees | Evoked potentials | habituation | psychophysiology | sensorimotor gating | posttraumatic stress disorder | BASE-LINE | SEROTONERGIC ACTIVITY | PREPULSE INHIBITION | PSYCHIATRY | PSYCHOLOGY, CLINICAL | TORTURE | PSYCHOLOGY | RESPONSES | WOMEN | VIETNAM VETERANS | ACOUSTIC STARTLE | PHYSIOLOGICAL REACTIVITY | P50 SUPPRESSION | Psychophysiological aspects | Suppression | Event-related potentials | Posttraumatic stress disorder | Refugees | Gender | Habituation | Startle response | Sensory integration | Post-traumatic stress disorder | Gating | Age | Startle eyeblink response | Hypersensitivity | Sensory processes | EEG | Auditory evoked potentials | Severity | Trauma | Patients | Stress | Sensorimotor gating | Studies | Ethnicity | Reactivity | Country of origin | Post traumatic stress disorder | Information processing | Models | Prepulse inhibition | Survivors | Brain Imaging | War | Torture | PTSD (DSM-5) | Adults | PTSD (ICD-10) | Startle Reflex | Biologic Markers
sensory gating | refugees | Evoked potentials | habituation | psychophysiology | sensorimotor gating | posttraumatic stress disorder | BASE-LINE | SEROTONERGIC ACTIVITY | PREPULSE INHIBITION | PSYCHIATRY | PSYCHOLOGY, CLINICAL | TORTURE | PSYCHOLOGY | RESPONSES | WOMEN | VIETNAM VETERANS | ACOUSTIC STARTLE | PHYSIOLOGICAL REACTIVITY | P50 SUPPRESSION | Psychophysiological aspects | Suppression | Event-related potentials | Posttraumatic stress disorder | Refugees | Gender | Habituation | Startle response | Sensory integration | Post-traumatic stress disorder | Gating | Age | Startle eyeblink response | Hypersensitivity | Sensory processes | EEG | Auditory evoked potentials | Severity | Trauma | Patients | Stress | Sensorimotor gating | Studies | Ethnicity | Reactivity | Country of origin | Post traumatic stress disorder | Information processing | Models | Prepulse inhibition | Survivors | Brain Imaging | War | Torture | PTSD (DSM-5) | Adults | PTSD (ICD-10) | Startle Reflex | Biologic Markers
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2018, Volume 142, Issue 8, pp. 1580 - 1585
Accumulating evidence suggest that Propionibacterium acnes may play a role in prostate carcinogenesis, but data are so far limited and inconclusive. The aim of...
acne vulgaris | prostate cancer | Propionibacterium acnes | inflammation | POPULATION | ADULT BODY-SIZE | SPECIMENS | ONCOLOGY | DISEASE | PROPIONIBACTERIUM-ACNES | COHORT | VULGARIS | EPIDEMIOLOGY | HISTORY | Acne Vulgaris - complications | Sweden | Follow-Up Studies | Military Personnel | Humans | Middle Aged | Risk Factors | Adolescent | Prostatic Neoplasms - etiology | Male | Cohort Studies | Adolescence | Draft | Draft registration | Prostate cancer | Risk factors | Statistical analysis | Acne | Health risks | Risk | Population studies | Carcinogenesis | Confidence intervals | Carcinogens | Child development | Diagnosis | Adolescents | Health risk assessment | Prostate | Cancer | Military | Index Medicus | Cancer Epidemiology | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Propionibacterium acnes; prostate cancer; acne vulgaris; inflammation; acne vulgaris | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
acne vulgaris | prostate cancer | Propionibacterium acnes | inflammation | POPULATION | ADULT BODY-SIZE | SPECIMENS | ONCOLOGY | DISEASE | PROPIONIBACTERIUM-ACNES | COHORT | VULGARIS | EPIDEMIOLOGY | HISTORY | Acne Vulgaris - complications | Sweden | Follow-Up Studies | Military Personnel | Humans | Middle Aged | Risk Factors | Adolescent | Prostatic Neoplasms - etiology | Male | Cohort Studies | Adolescence | Draft | Draft registration | Prostate cancer | Risk factors | Statistical analysis | Acne | Health risks | Risk | Population studies | Carcinogenesis | Confidence intervals | Carcinogens | Child development | Diagnosis | Adolescents | Health risk assessment | Prostate | Cancer | Military | Index Medicus | Cancer Epidemiology | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Propionibacterium acnes; prostate cancer; acne vulgaris; inflammation; acne vulgaris | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article
Current Diabetes Reports, ISSN 1534-4827, 12/2018, Volume 18, Issue 12, pp. 1 - 14
The environmental triggers of islet autoimmunity leading to type 1 diabetes (T1D) need to be elucidated to inform primary prevention. The Environmental...
Autoimmunity | Diabetes | Children | Medicine & Public Health | Type 1 diabetes | AUTOANTIBODY APPEARANCE | EARLY-CHILDHOOD | 1ST YEAR | CELIAC-DISEASE | RESPIRATORY-INFECTIONS | GENETIC RISK | ENDOCRINOLOGY & METABOLISM | SOCIODEMOGRAPHIC FACTORS | ISLET AUTOIMMUNITY | BETA-CELL AUTOIMMUNITY | INCIDENCE TRENDS | Pancreatic beta cells | Thyroid diseases | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Endocrinology and Diabetes
Autoimmunity | Diabetes | Children | Medicine & Public Health | Type 1 diabetes | AUTOANTIBODY APPEARANCE | EARLY-CHILDHOOD | 1ST YEAR | CELIAC-DISEASE | RESPIRATORY-INFECTIONS | GENETIC RISK | ENDOCRINOLOGY & METABOLISM | SOCIODEMOGRAPHIC FACTORS | ISLET AUTOIMMUNITY | BETA-CELL AUTOIMMUNITY | INCIDENCE TRENDS | Pancreatic beta cells | Thyroid diseases | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Endocrinology and Diabetes
Journal Article