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ChemMedChem, ISSN 1860-7179, 12/2017, Volume 12, Issue 24, pp. 2054 - 2065
Cisplatin and other platinum‐based drugs are well‐known valid anticancer drugs. However, during chemotherapy, the presence of numerous side effects and the... 
carbenes | caspases | reactive oxygen species | cytochromes | transmetalation | ANTIPROLIFERATIVE ACTIVITY | CHEMISTRY, MEDICINAL | CANCER CELL-GROWTH | N-HETEROCYCLIC CARBENES | CYTOTOXIC ACTIVITY | IN-VITRO | CORRESPONDING GOLD(I) | BIOLOGICAL-ACTIVITY | LIGANDS SYNTHESIS | NATURAL-PRODUCTS SYNTHESIS | PHARMACOLOGY & PHARMACY | DERIVATIVES | Gold - chemistry | Cell Survival - drug effects | Silver - pharmacology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Methane - analogs & derivatives | Antineoplastic Agents - chemical synthesis | Humans | Methane - pharmacology | Cells, Cultured | Silver - chemistry | Mitochondria - metabolism | Structure-Activity Relationship | Gold - pharmacology | Mitochondria - drug effects | Antineoplastic Agents - chemistry | Dose-Response Relationship, Drug | Methane - chemistry | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Drug Screening Assays, Antitumor | Cytochrome c | Silver | Chemotherapy | Analysis | Ovarian cancer | Apoptosis | Cancer | Drugs | Cell culture | Reactive oxygen species | Ovarian carcinoma | Organometallic compounds | Cytotoxicity | Cancer therapies | Anticancer properties | Mitochondria | Synthesis | Antitumor agents | Platinum | HeLa cells | Gold | Poly(ADP-ribose) polymerase | Breast cancer | Tumor cell lines | Cisplatin | Side effects | Poly(ADP-ribose) Polymerase 1 | Cell death | Antitumor activity | Cytoplasm
Journal Article
Nutrients, ISSN 2072-6643, 2019, Volume 11, Issue 4, p. 915
In this study, two capsaicin analogues, N-eicosapentaenoyl vanillylamine (EPVA) and N-docosahexaenoyl vanillylamine (DHVA), were enzymatically synthesized from... 
Vanillylamide | Obesity | Inflammation | Diabetes | Fatty acid amides | PUFA | fatty acid amides | N-ACYLETHANOLAMINES | NITRIC-OXIDE SYNTHASE | BLOOD-GLUCOSE | NECROSIS-FACTOR-ALPHA | PPAR-GAMMA ACTIVATION | DOCOSAHEXAENOYL SEROTONIN | NUTRITION & DIETETICS | ANTIINFLAMMATORY PROPERTIES | SENSORY NERVE DESENSITIZATION | inflammation | GENE-EXPRESSION | vanillylamide | diabetes | obesity | GLUCOSE-TOLERANCE | Calcium - metabolism | Capsaicin - pharmacology | Eicosapentaenoic Acid - analogs & derivatives | Fatty Acids, Omega-3 - chemistry | Capsaicin - chemistry | Inflammation - metabolism | Insulin-Secreting Cells - metabolism | Eicosapentaenoic Acid - pharmacology | Molecular Structure | Cell Survival - drug effects | Docosahexaenoic Acids - chemical synthesis | Eicosapentaenoic Acid - chemistry | Docosahexaenoic Acids - chemistry | Rats | Capsaicin - analogs & derivatives | Eicosapentaenoic Acid - chemical synthesis | Docosahexaenoic Acids - analogs & derivatives | Gene Expression Regulation - drug effects | Docosahexaenoic Acids - pharmacology | Insulin - metabolism | Macrophages - metabolism | Animals | Insulin-Secreting Cells - drug effects | Cell Line, Tumor | Macrophages - drug effects | RAW 264.7 Cells | Mice | Adipose tissue | Polyunsaturated fatty acids | Capsaicin | Interleukin | Vanillylamine | Prostaglandin E2 | Adipocytes | Glucose | Macrophages | Adiponectin | Interleukin 6 | Proteins | Pain | Tumor necrosis factor-TNF | Pancreas | Invasiveness | Diabetes mellitus | Breast cancer | Tumor necrosis factor-α | Metabolism | Secretions | Gene expression | Insulin | Fatty acids | Olvanil | Beta cells | Properties (attributes) | Monocytes | Eicosapentaenoic acid | Monocyte chemoattractant protein 1 | Apoptosis
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2019, Volume 29, Issue 14, pp. 1761 - 1764
[Display omitted] The G-protein-coupled receptor 40 (GPR40) is an attractive molecular target for the treatment of type 2 diabetes mellitus. Previously, based... 
Type 2 diabetes | Oleic acid | GPR40 allosteric site | Quercetin | Insulin secretion | POTENT | CHEMISTRY, MEDICINAL | STRUCTURAL BASIS | INSULIN-SECRETION | CHEMISTRY, ORGANIC | RECEPTOR | FLUORINE | Drugstores | Monounsaturated fatty acids | Catechin | Pharmacy
Journal Article
Eating and weight disorders : EWD, ISSN 1590-1262, 07/2019
The present study examined the predictive value of early maladaptive schema (EMS) domains on the diagnosis of binge eating disorder (BED). Seventy obese... 
Journal Article
NUTRIENTS, ISSN 2072-6643, 09/2019, Volume 11, Issue 9, p. 1995
Alterations of the immune system are known in eating disorders (EDs), however the importance of cytokine balance in this context has not been clarified. We... 
MACROPHAGE INFILTRATION | PROTEIN | binge eating disorder | growth factors | BULIMIA-NERVOSA | NECROSIS-FACTOR-ALPHA | eating disorders | INTERLEUKIN-10 | anorexia nervosa | MALNUTRITION | ANOREXIA-NERVOSA | NUTRITION & DIETETICS | INTERFERON-GAMMA | MESSENGER-RNA | inflammation | cytokines | EXPRESSION | obesity | Night Eating Syndrome - blood | Binge-Eating Disorder - blood | Humans | Middle Aged | Night Eating Syndrome - psychology | Feeding and Eating Disorders - blood | Male | Feeding and Eating Disorders - immunology | Feeding and Eating Disorders - psychology | Case-Control Studies | Night Eating Syndrome - immunology | Intercellular Signaling Peptides and Proteins - blood | Anorexia Nervosa - immunology | Brain - metabolism | Young Adult | Binge-Eating Disorder - psychology | Time Factors | Adult | Female | Anorexia Nervosa - psychology | Binge-Eating Disorder - immunology | Weight Gain | Cytokines - blood | Cytokines - immunology | Body Mass Index | Binge-Eating Disorder - physiopathology | Brain - physiopathology | Anorexia Nervosa - physiopathology | Feeding Behavior | Feeding and Eating Disorders - physiopathology | Biomarkers - blood | Night Eating Syndrome - physiopathology | Anorexia Nervosa - blood | Weight Loss | Adolescent | Brain - immunology | Brain | Central nervous system | Disorders | Hypothalamus | Neuroendocrine system | Proteins | Body mass index | Immunology | Epidermal growth factor | Autonomic nervous system | Tumor necrosis factor-TNF | Behavior | Psychopathology | Malnutrition | Growth factors | Obesity | Cytokines | Salivary glands | Comorbidity | Immunoregulation | Eating disorders | Hypothalamic-pituitary-adrenal axis | Salivary gland | Inflammation | Secretions | Serum levels | Nutrition research | Hypotheses | Weight control | Mood | Body mass | Pituitary | Body size | Gastric juice
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 06/2016, Volume 16, Issue 9, pp. 738 - 742
Journal Article
by Ostuzzi, Giovanni and Mazzi, Maria Angela and Terlizzi, Samira and Bertolini, Federico and Aguglia, Andrea and Bartoli, Francesco and Bortolaso, Paola and Callegari, Camilla and Caroleo, Mariarita and Carrà, Giuseppe and Corbo, Mariangela and D'Agostino, Armando and Gastaldon, Chiara and Lucii, Claudio and Magliocco, Fabio and Martinotti, Giovanni and Nosé, Michela and Ostinelli, Edoardo Giuseppe and Papola, Davide and Piccinelli, Marco Piero and Piccoli, Alberto and Purgato, Marianna and Tabacchi, Tommaso and Turrini, Giulia and Ruggeri, Mirella and Barbui, Corrado and De Fazio, Pasquale and Raffaele, Gaetano and Chirico, Margherita and Cavallotti, Simone and Bolognesi, Simone and Debolini, Sara and Pierantozzi, Elisa and Fargnoli, Francesco and Del Zanna, Maria and Giannini, Alessandra and Luccarelli, Livia and De Capua, Alberto and Annese, Pasqua Maria and Cerretini, Massimiliano and Tozzi, Fior-Ella and Magnani, Nadia and Cardamone, Giuseppe and Bardicchia, Francesco and Facchi, Edvige and Soscia, Federica and Zotos, Spyridon and Biancosino, Bruno and Zonta, Filippo and Pompei, Francesco and Zizolfi, Daniele and Poloni, Nicola and Ielmini, Marta and Caselli, Ivano and Giana, Edoardo and Buzzi, Aldo and Diurni, Marcello and Milano, Anna and Sani, Emanuele and Calzolari, Roberta and Piccinelli, Marco and Cazzamalli, Sara and Alberini, Gabrio and Piantanida, Silvia and Costantini, Chiara and Paronelli, Chiara and Di Caro, Angela and Moretti, Valentina and Gozzi, Mauro and D'Ippolito, Chiara and Barbanti, Silva Veronica and Alessandro, Papalini and Campese, Ornella and Fiori, Federica and Lorusso, Marco and Di Capro, Lucia and Viceconte, Daniela and Mancini, Valerio and Suraniti, Francesco and Signorelli, Maria Salvina and Rossi, Eugenio and Lupoli, Pasqualino and Menchetti, Marco and Terzi, Laura and Boso, Marianna and Risaro, Paolo and De Paoli, Giuseppe and Catania, Cristina and Tarricone, Ilaria and Caretto, Valentina and Storbini, Viviana and Emiliani, Roberta and Balzarro, Beatrice and Nava, Roberto and Bono, Adele and Provenzi, Milena and Brambilla, Giulia and Aspesi, Flora and Tremolada, Martina and Castagna, Gloria and ... and STAR Network Investigators and the STAR Network Investigators
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0201371
Journal Article