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NATURE MATERIALS, ISSN 1476-1122, 05/2019, Volume 18, Issue 5, pp. 414 - 418
Highly quantitative, robust, single-cell analyses can help to unravel disease heterogeneity and lead to clinical insights, particularly for complex and chronic... 
CHEMISTRY, PHYSICAL | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | Machine vision | Computer vision | Machine learning
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 05/2019, Volume 10, Issue 1, pp. 2082 - 6
Single-cell resolution technologies warrant computational methods that capture cell heterogeneity while allowing efficient comparisons of populations. Here, we... 
RESPONSES | STATES | MULTIDISCIPLINARY SCIENCES | Heterogeneity | Populations | Profiling | Multisensor fusion | Data integration | Computer applications | Performance prediction | Cell fusion
Journal Article
PLOS BIOLOGY, ISSN 1544-9173, 06/2019, Volume 17, Issue 6, p. e3000340
Journal Article
NATURE METHODS, ISSN 1548-7091, 12/2019, Volume 16, Issue 12, pp. 1247 - 1247
Segmenting the nuclei of cells in microscopy images is often the first step in the quantitative analysis of imaging data for biological and biomedical... 
ALGORITHMS | IMAGES | BIOCHEMICAL RESEARCH METHODS | CELL-NUCLEI
Journal Article
Nature communications, 09/2017, Volume 8, Issue 1, p. 463
We show that deep convolutional neural networks combined with nonlinear dimension reduction enable reconstructing biological processes based on raw image data.... 
Journal Article
Cytometry Part A, ISSN 1552-4922, 09/2019, Volume 95, Issue 9, pp. 952 - 965
Identifying nuclei is often a critical first step in analyzing microscopy images of cells and classical image processing algorithms are most commonly used for... 
nuclear segmentation | deep learning | image analysis | chemical screen | fluorescence imaging | Algorithms | Image processing | Neural networks | Learning strategies | Machine learning | Fluorescence | Equipment and supplies | Data mining | Evaluation | Segmentation | Source code | Nuclei | Deep learning | Learning | Image segmentation | Cytometry | Accuracy | Microscopy | Computer applications | Original
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1683, pp. 89 - 112
Journal Article
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 07/2019
Identifying nuclei is often a critical first step in analyzing microscopy images of cells and classical image processing algorithms are most commonly used for... 
Journal Article
Nature Methods, ISSN 1548-7091, 05/2013, Volume 10, Issue 5, p. 445
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, p. 1987
Patients with a germline mutation in von Hippel-Lindau (VHL) develop renal cell cancers and hypervascular tumors of the brain, adrenal glands, and pancreas as... 
Physiological aspects | Transcription factors | Genetic aspects | Research | Gene expression | Von Hippel-Lindau disease | Awards & honors | Medical research | Mortality | Zebrafish | Kinases | Metabolism | Experiments | Embryos | Proteins | Angiogenesis | Hospitals | Brain research | Plasmids | Medical prognosis | Hypoxia | Mutation | Tumors | Cancer
Journal Article
Nature Methods, ISSN 1548-7091, 05/2013, Volume 10, Issue 5, p. 445
Journal Article