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Cell Stem Cell, ISSN 1934-5909, 06/2016, Volume 18, Issue 6, pp. 769 - 781
Leber congenital amaurosis (LCA) is an inherited retinal dystrophy that causes childhood blindness. Photoreceptors are especially sensitive to an intronic... 
RETINAL DEGENERATION | JOUBERT-SYNDROME | CELLS | LEBER CONGENITAL AMAUROSIS | TRANSITION ZONE | MUTATION | GENES | LINKED RETINITIS-PIGMENTOSA | CEP290 | CENTROSOMAL PROTEIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Leber Congenital Amaurosis - pathology | Optic Disk - cytology | Retinal Pigment Epithelium - metabolism | Humans | Blindness - pathology | Male | Organogenesis - drug effects | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Retinal Pigment Epithelium - pathology | Retinal Pigment Epithelium - ultrastructure | RNA Splicing - genetics | Antigens, Neoplasm - metabolism | Cilia - drug effects | Inheritance Patterns - genetics | Blindness - therapy | Induced Pluripotent Stem Cells - cytology | Neoplasm Proteins - genetics | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Retinal Pigment Epithelium - drug effects | rab GTP-Binding Proteins - metabolism | Antigens, Neoplasm - genetics | RNA Splicing - drug effects | Photoreceptor Cells, Vertebrate - ultrastructure | Induced Pluripotent Stem Cells - drug effects | RNA, Messenger - genetics | Exons - genetics | Fibroblasts - pathology | Cilia - metabolism | Eye Proteins - metabolism | Cell Differentiation - drug effects | Fibroblasts - drug effects | Morpholinos - pharmacology | Opsins - metabolism | Photoreceptor Cells, Vertebrate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Index Medicus
Journal Article
Nature Biotechnology, ISSN 1087-0156, 04/2018, Volume 36, Issue 4, pp. 1 - 10
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2005, Volume 7, Issue 3, pp. 319 - 321
Journal Article
Experimental Neurology, ISSN 0014-4886, 2008, Volume 214, Issue 2, pp. 347 - 361
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8152 - e8152
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs).... 
PROGENITOR CELLS | MACULAR TRANSLOCATION | RCS RAT | SUBRETINAL TRANSPLANTATION | VISUAL FUNCTION | RPE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | AUTOLOGOUS TRANSPLANTATION | HUMAN FIBROBLASTS | PHOTORECEPTOR DEGENERATION | Biomarkers - metabolism | Epithelial Cells - transplantation | Immunohistochemistry | Cell Polarity | Photoreceptor Cells, Vertebrate - ultrastructure | Retinal Pigment Epithelium - transplantation | Cell Survival | Humans | Proto-Oncogene Proteins c-fos - metabolism | Retinal Diseases - therapy | Rats | Photoreceptor Cells, Vertebrate - cytology | Macrophages - cytology | Vision, Ocular - physiology | Animals | Retinal Pigment Epithelium - ultrastructure | Cell Shape | Retinal Diseases - pathology | Cell Differentiation | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Retinal Diseases - physiopathology | Phagocytosis | Retinal Pigment Epithelium - cytology | Macular degeneration | Epithelium | Embryonic stem cells | Health aspects | Monomolecular films | Transformation | Transcription factors | Pathogenesis | Embryo cells | Stem cell transplantation | Retina | Transplantation | Retinal pigment epithelium | Visual perception | Engineering | Allografts | Fibroblasts | Degeneration | Age | Medical personnel | Cell survival | Developmental biology | Medical treatment | Gene expression | Somatic cells | Stem cells | Photoreceptors | Pluripotency | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 02/2015, Volume 24, Issue 4, pp. 972 - 986
Journal Article
Journal Article
Journal Article
Journal Article
NEUROREPORT, ISSN 0959-4965, 02/2014, Volume 25, Issue 3, pp. 147 - 148
Several clinical trials of cell based therapy for retinal degeneration are currently recruiting worldwide. This clinical translation is based on over a decade... 
NEUROSCIENCES
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