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Circulation, ISSN 0009-7322, 12/2019, Volume 140, Issue 25, pp. 2108 - 2118
Following regulatory guidance set forth in 2008 by the US Food and Drug Administration for new drugs for type 2 diabetes mellitus, many large randomized,... 
Journal Article
by Whelan, Timothy J and Julian, Jim A and Berrang, Tanya S and Kim, Do-Hoon and Kim, Christina and Germain, Francois and Germain, Isabelle and Nichol, Alan M and Akra, Mohamed and Lavertu, Sophie and Fyles, Anthony and Trotter, Theresa and Perera, Francisco E and Balkwill, Susan and Chafe, Susan and McGowan, Thomas and Muanza, Thierry and Beckham, Wayne A and Chua, Boon H and Gu, Chu Shu and Levine, Mark N and Olivotto, Ivo A and Leong, Carson and Lester, Beverly Helen and Kwan, Winkle Bingchung and Abd-El-Malek, Medhat Zikry and Cheung, Arthur and Almahmudi, Maha and Broomfield, Joel and Sia, Michael and Reed, Melanie Jean and Wilson, Jane and Mohamed, Islam Gharib and Holloway, Caroline and Mills, Kenneth and Petrik, David W and Crook, Juanita Mary and Wong, Frances Lai-Wah and Mills Carolan, Hannah and Voduc, David and Ingledew, Paris-Ann and Nguyen, Sonia and Nguyen, David and Keyes, Mira and Weir, Lorna M and Tyldesley, Scott and Lim, Peter and Aquino Parsons, Christina and Olson, Robert and Blood, Paul and Wai, Elaine Sze-Sze and Truong, Pauline and Kader, Hosam (Sam) and Alexander, Abraham and Mohd Mydin, Aminudin Rahman and Smith, Sally and Vlachaki, Maria and Panet-Raymond, Valerie and Lupe, Krystine and Goulart, Jennifer and Chu, Karen and Canavan, Joycelin and Caon, Julianna and Tyler, Susan and Shahid, Negin and Lam, Jacqueline and Amanie, John and Severin, Diane Marie and Abdul Karim, Bassam and Tankel, Keith and Pervez, Nadeem and Joseph, Kurian and Gabos, Zsolt and Krause, Barbara and Huang, Roger and Huang, Fleur and Phan, Tien and Craighead, Peter and Yan, Elizabeth and MacKinnon, J.A. (Jack) and Nordal, Robert and Husain, Siraj and Voroney, Jon-Paul and Sinha, Richie and Pinilla, James and Cooke, Andrew and Vijayraghavan, Kalyani and Latosinsky, Steven and Saettler, Elizabeth and Lau, Yiu-Keung (James) and Krahn, Marianne and MacIntosh, Ethel and Nashed, Maged and Bashir, Bashir and Torri, Vamsee and Goldenberg, Benjamin and Basrur, Vasanth and Rachakonda, Ramana and Gopaul, Darin and Shahi, Sundeep and ... and RAPID Trial Investigators
The Lancet, ISSN 0140-6736, 12/2019, Volume 394, Issue 10215, pp. 2165 - 2172
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 16
Numerous studies have proposed biomarkers based on magnetic resonance imaging (MRI) to detect and predict the risk of evolution toward Alzheimer’s disease... 
Biomarkers | Nuclear magnetic resonance--NMR | Magnetic resonance imaging | Alzheimer's disease | Hippocampus | Classification | Computer Science | Medical Imaging
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 1 - 12
Adult neurogenesis occurs in the dentate gyrus of the hippocampus during adulthood and contributes to sustaining the hippocampal formation. To investigate... 
SURFACE-BASED ANALYSIS | BIOMARKERS | SET | GENE | MEMORY | VARIANTS | ADULT NEUROGENESIS | MULTIDISCIPLINARY SCIENCES | PROGRESS | PHENOTYPES | IMPAIRMENT | Neuroimaging | Dentate gyrus | Phenotypes | Statistical analysis | Leukocyte migration | Facilitated communication | Association analysis | Genomes | Gene expression | Neurogenesis | Hippocampus | Cell migration
Journal Article
by Lee, Garam and Nho, Kwangsik and Kang, Byungkon and Sohn, Kyung-Ah and Kim, Dokyoon and Weiner, Michael W and Aisen, Paul and Petersen, Ronald and Jack, Clifford R and Jagust, William and Trojanowki, John Q and Toga, Arthur W and Beckett, Laurel and Green, Robert C and Saykin, Andrew J and Morris, John and Shaw, Leslie M and Khachaturian, Zaven and Sorensen, Greg and Carrillo, Maria and Kuller, Lew and Raichle, Marc and Paul, Steven and Davies, Peter and Fillit, Howard and Hefti, Franz and Holtzman, Davie and Mesulam, M. Marcel and Potter, William and Snyder, Peter and Montine, Tom and Thomas, Ronald G and Donohue, Michael and Walter, Sarah and Sather, Tamie and Jiminez, Gus and Balasubramanian, Archana B and Mason, Jennifer and Sim, Iris and Harvey, Danielle and Bernstein, Matthew and Fox, Nick and Thompson, Paul and Schuff, Norbert and DeCArli, Charles and Borowski, Bret and Gunter, Jeff and Senjem, Matt and Vemuri, Prashanthi and Jones, David and Kantarci, Kejal and Ward, Chad and Koeppe, Robert A and Foster, Norm and Reiman, Eric M and Chen, Kewei and Mathis, Chet and Landau, Susan and Cairns, Nigel J and Householder, Erin and Taylor-Reinwald, Lisa and Lee, Virginia and Korecka, Magdalena and Figurski, Michal and Crawford, Karen and Neu, Scott and Foroud, Tatiana M and Potkin, Steven and Shen, Li and Faber, Kelley and Kim, Sungeun and Tha, Lean and Frank, Richard and Hsiao, John and Kaye, Jeffrey and Quinn, Joseph and Silbert, Lisa and Lind, Betty and Carter, Raina and Dolen, Sara and Ances, Beau and Carroll, Maria and Creech, Mary L and Franklin, Erin and Mintun, Mark A and Schneider, Stacy and Oliver, Angela and Schneider, Lon S and Pawluczyk, Sonia and Beccera, Mauricio and Teodoro, Liberty and Spann, Bryan M and Brewer, James and Vanderswag, Helen and Fleisher, Adam and Marson, Daniel and Griffith, Randall and Clark, David and Geldmacher, David and Brockington, John and ... and for Alzheimer’s Disease Neuroimaging Initiative
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 12
Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by a decline in cognitive functions with no validated disease modifying treatment.... 
Learning | Neuroimaging | Medical imaging | Prediction models | Neural networks | Cognitive ability | Clinical trials | Biomarkers | Cerebrospinal fluid | Alzheimer's disease
Journal Article
Journal of Advanced Nursing, ISSN 0309-2402, 11/2019, Volume 75, Issue 11, pp. 2910 - 2922
Aims To explore stakeholder perspectives of compassion in nursing. Background Studies show that nurses’ compassion can be characterized by 11 characteristics.... 
qualitative | strengths | model | nurse education | teaching | compassion | stakeholders | Professional practices | Competence | Sympathy | Attitudes | Empathy | Teaching | Nurse tutors | Nursing education | Interpersonal skills | Nurse-Patient communication | Nursing | Students | Motivation | Analysis | Nurses | Stakeholders | Content analysis
Journal Article
The Lancet, ISSN 0140-6736, 11/2019, Volume 394, pp. S86 - S86
Abstract Background Clinical research generates evidence for improving clinical management and control of emerging epidemics. However, experiences from... 
Virus diseases | Epidemics | Medical research | World health | Health care reform | Clinical trials | Medicine, Experimental | United Kingdom | Medical screening
Journal Article
by Anker, Stefan D and Butler, Javed and Filippatos, Gerasimos S and Jamal, Waheed and Salsali, Afshin and Schnee, Janet and Kimura, Karen and Zeller, Cordula and George, Jyothis and Brueckmann, Martina and Zannad, Faiez and Packer, Milton and Packer, Milton and Anker, Stefan D and Butler, Javed and Filippatos, Gerasimos S and Zannad, Faiez and George, Jyothis and Brueckmann, Martina and Perrone, Sergio and Nicholls, Stephen and Janssens, Stefan and Bocchi, Edmar and Giannetti, Nadia and Verma, Subodh and Jian, Zhang and Gomez Mesa, Juan Esteban and Spinar, Jindrich and Böhm, Michael and Merkely, Bela and Chopra, Vijay and Senni, Michele and Taddi, Stefano and Tsutsui, Hiroyuki and Chuquiure, Eduardo and La Rocca, Hans Pieter Brunner and Ponikowski, Piotr and Vinereanu, Dragos and Sim, David and Choi, Dong‐Ju and Juanatey, Jose Ramon Gonzalez and Squire, Iain and Butler, Javed and Januzzi, James and Pina, Ileana and Pocock, Stuart J and Carson, Peter and Doehner, Wolfram and Miller, Alan and Haas, Markus and Pehrson, Steen and Komajda, Michel and Anand, Inder and Teerlink, John and Rabinstein, Alejandro and Steiner, Thorsten and Kamel, Hooman and Tsivgoulis, Georgios and Lewis, James and Freston, James and Kaplowitz, Neil and Mann, Johannes and Petrie, Mark and Bernstein, Richard and Cheung, Alfred and Green, Jennifer and Januzzi, James and Kaul, Sanjay and Ping, Carolyn Lam Su and Lip, Gregory and Marx, Nikolaus and McCullough, Peter and Mehta, Cyrus and Ponikowski, Piotr and Rosenstock, Julio and Sattar, Naveed and Scirica, Benjamin and Tsutsui, Hiroyuki and Verma, Subodh and Wanner, Christoph and Welty, Francine K and Parhofer, Klaus G and Clayton, Tim and Pedersen, Terje R and Lees, Kennedy R and Konstam, Marvin A and Greenberg, Barry and Palmer, Mike and EMPEROR-Preserved Trial Committees and Investigators and on behalf of the EMPEROR‐Preserved Trial Committees and Investigators
European Journal of Heart Failure, ISSN 1388-9842, 10/2019, Volume 21, Issue 10, pp. 1279 - 1287
Background The principal biological processes that characterize heart failure with a preserved ejection fraction (HFpEF) are systemic inflammation, epicardial... 
Heart failure | Diabetes | Trial design | SGLT2 inhibitors
Journal Article