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Annual Review of Physiology, ISSN 0066-4278, 01/2011, Volume 73, p. 135
Synthetic chemicals currently used in a variety of industrial and agricultural applications are leading to widespread contamination of the environment. Even... 
Human exposure | Synthetic products | Physiology | Hormones | Epidemiology | Chemicals | Metabolic disorders
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2019, Volume 14, Issue 8, p. e0220894
Transcriptional regulations exert a critical control of metabolic homeostasis. In particular, the nuclear receptors (NRs) are involved in regulating numerous... 
ACTIVATION | ALPHA GENE | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | MOUSE-LIVER | X-RECEPTOR | PROLIFERATION | BINDING | EXPRESSION | BILE-ACIDS | INHIBIT | Homeostasis | Research | Gene expression | Liver cells | Cell cycle | Transcription | Liver | Genes | Genomics | Crosstalk | Lipids | Systems analysis | Metabolism | Cell differentiation | Kinases | Nuclear receptors | Glucose metabolism | Receptors | Cell growth | Hepatocytes | Agonists | Lipid metabolism | Bile
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 02/2010, Volume 118, Issue 2, p. 234
  The modulation of energetic homeostasis by pollutants has recently emerged as a potential contributor to the onset of metabolic disorders. Diethylhexyl... 
Physiological aspects | Energy metabolism | Cell receptors | Research | Bioenergetics
Journal Article
by Bultet, Lisandra Aguilar and Aguilar-Rodríguez, José and Ahrens, Christian H and Ahrné, Erik Lennart and Ai, Ni and Aimo, Lucila and Akalin, Altuna and Aleksiev, Tyanko and Alocci, Davide and Altenhoff, Adrian and Alves, Isabel and Ambrosini, Giovanna and Pedone, Pascale Anderle and Angelino, Paolo and Anisimova, Maria and Appel, Ron and Argoud-Puy, Ghislaine and Arnold, Konstantin and Arpat, Bulak and Artimo, Panu and Ascencao, Kelly and Auchincloss, Andrea and Axelsen, Kristian and Gerritsen, Vivienne Baillie and Bairoch, Amos and Bansal, Parit and Baratin, Delphine and Barbato, Alessandro and Barbié, Valérie and Barras, David and Barreiro, Maria and Barret, Sophie and Bastian, Frederic and Neto, Teresamanuela Batista and Baudis, Michael and Beaudoing, Emmanuel and Beckmann, Jacques S and Bekkar, Amel Kawter and Ben Hamida Cammoun, Leila and Benmohammed, Sara and Bernard, Madeleine and Bertelli, Claire and Bertoni, Martino and Bienert, Stefan and Bignucolo, Olivier and Bilbao, Aivett and Bilican, Adem and Blank, Diana and Blatter, Marie-Claude and Blum, Lorenz and Bocquet, Jocelyne and Boeckmann, Brigitte and Bolleman, Jerven Tjalling and Bordoli, Lorenza and Bosshard, Lars and Bouchet, Gerard and Bougueleret, Lydie and Boutet, Emmanuel and Bovigny, Christophe and Bratulic, Sinisa and Breuza, Lionel and Bridge, Alan James and Britan, Aurore and Brito, Francisco and Frazão, Josias Brito and Bruggmann, Rémy and Bucher, Philipp and Burdet, Frédéric and Burger, Lukas and Cabello, Elena Maria and Gomez, Ruben Martin Cabezon and Calderon, Sandra and Cannarozzi, Gina and Carl, Sarah and Casas, Cristina Casals and Catherinet, Sebastien and Périer, Rouayda Cavin and Charpilloz, Christophe and Chaskar, Prasad Datatray and Chen, Weihua and Pepe, Anush Chiappino and Chopard, Bastien and Chu, Hoi Yee and Civic, Natacha and Claassen, Manfred and Clottu, Sylvie and Colombo, Martino and Cosandier, Isabelle and Coudert, Elisabeth and Crespo, Isaac and Creus, Marc and Cuche, Béatrice and Cuendet, Michel A and Cusin, Isabelle and Daga, Neha and Daina, Antoine and Dauvillier, Jér Ôme and David, Fabrice and Davydov, Iakov and De Sa Ricca Manadelo Ferreira, Mariana and ... and SIB Swiss Inst Bioinformatics
Nucleic Acids Research, ISSN 0305-1048, 2016, Volume 44, Issue 1, pp. D27 - D37
The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the... 
PROTEIN MODELS | QUALITY | REGULATORY SITES | LANDSCAPE | KNOWLEDGEBASE | ARCHIVE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPOSITORY | EXPRESSION DATA | TOOLS | PREDICTION | Database Issue
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2009, Volume 39, Issue 7, pp. 1902 - 1913
MAPK phosphatase‐1 (MKP‐1) is a protein phosphatase that plays a crucial role in innate immunity. This phosphatase inactivates ERK1/2, which are involved in... 
Activation | Phosphatases | Proliferation | Kinases | Macrophage | MAP KINASE | ELEMENT-BINDING PROTEIN | IMMUNOLOGY | LIPOPOLYSACCHARIDE-STIMULATED MACROPHAGES | SIGNAL-TRANSDUCTION | INNATE IMMUNE-RESPONSES | PROTEIN-KINASE PHOSPHATASE-1 | NEUROENDOCRINE CELLS | NF-KAPPA-B | DEPENDENT ACTIVATION | MOLECULAR-MECHANISMS | RNA, Small Interfering - genetics | Gene Expression - drug effects | JNK Mitogen-Activated Protein Kinases - metabolism | Transcription Factor AP-1 - metabolism | Transfection | Chromatin Immunoprecipitation | Macrophage Colony-Stimulating Factor - pharmacology | Bone Marrow Cells - drug effects | Electrophoretic Mobility Shift Assay | JNK Mitogen-Activated Protein Kinases - genetics | Binding Sites | Dual Specificity Phosphatase 1 - genetics | Proto-Oncogene Proteins c-raf - genetics | Bone Marrow Cells - cytology | Proto-Oncogene Proteins c-jun - genetics | Macrophages - cytology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Proto-Oncogene Proteins c-raf - metabolism | Macrophages - metabolism | Animals | Proto-Oncogene Proteins c-jun - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Lipopolysaccharides - pharmacology | Protein Binding | Dual Specificity Phosphatase 1 - metabolism | Macrophages - drug effects | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Kinetics | Macrophage Activation - drug effects | Bone Marrow Cells - metabolism | Index Medicus
Journal Article
Scientific Data, ISSN 2052-4463, 12/2019, Volume 6, Issue 1, pp. 1 - 4
UniProt continues to support the ongoing process of making scientific data FAIR. Here we contribute to this process with a FAIRness assessment of our UniProtKB... 
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 9/2018, Volume 55, Issue 9, pp. 7216 - 7228
Lipid metabolism, specifically fatty acid oxidation (FAO) mediated by carnitine palmitoyltransferase (CPT) 1A, has been described to be an important actor of... 
Fatty acid oxidation | Neurology | Neurosciences | CPT1A | Biomedicine | Ghrelin | Cortical neurons | Neurobiology | GABA | Cell Biology | MOUSE-BRAIN | GERBIL HIPPOCAMPUS | INCREASES FOOD-INTAKE | ALZHEIMERS-DISEASE | NEUROSCIENCES | ENERGY-BALANCE | BODY-WEIGHT | MESSENGER-RNA | THERAPEUTIC TARGET | SHUNT ENZYMES | HORMONE SECRETAGOGUE RECEPTOR | Oxidation-Reduction | gamma-Aminobutyric Acid - metabolism | Mice, Inbred C57BL | Cells, Cultured | Citric Acid Cycle - drug effects | Ghrelin - pharmacology | Cerebral Cortex - metabolism | Animals | Hypothalamus - metabolism | Metabolome - drug effects | Carnitine O-Palmitoyltransferase - metabolism | Citrates - metabolism | Gene Deletion | Neurons - metabolism | Cerebral Cortex - drug effects | Hypothalamus - drug effects | Ketoglutaric Acids - metabolism | Neurons - drug effects | Fatty Acids - metabolism | Physiological aspects | Enzymes | Oxidation-reduction reaction | Fatty acids | Carnitine | Brain | 4-Aminobutyrate transaminase | Transaminase | Cortex | Central nervous system | Oxygen consumption | Hypothalamus | Metabolism | Palmitoyltransferase | Ablation | Carnitine palmitoyltransferase | Citric acid | γ-Aminobutyric acid | Mitochondria | Enzymatic activity | Mice | Oxidation | Lipid metabolism | Hipotàlem | Cerebral cortex | Hormones peptídiques | Metabolisme dels lípids | Peptide hormones | Escorça cerebral | Àcids grassos
Journal Article