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1. CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: A systematic review and meta-analysis
by Holmes, Michael V and Perel, Pablo and Shah, Tina and Hingorani, Aroon D and Casas, Juan P
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 12/2011, Volume 306, Issue 24, pp. 2704 - 2714
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hemorrhage - epidemiology | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Genotype | Risk | Ticlopidine - analogs & derivatives | Angioplasty, Balloon, Coronary | Randomized Controlled Trials as Topic | Cytochrome P-450 CYP2C19 | Platelet Function Tests | Ticlopidine - adverse effects | Ticlopidine - metabolism | Cardiovascular Diseases - epidemiology | Platelet Aggregation Inhibitors - pharmacology | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - metabolism | Thrombosis - prevention & control | Platelet Aggregation Inhibitors - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Genotype & phenotype | Systematic review | Cardiovascular disease | Genetic testing | Meta-analysis
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2. Full Text Statins for all by the age of 50 years?
by Ebrahim, Shah and Casas, Juan P
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 380, Issue 9841, pp. 545 - 547
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cholesterol, LDL - blood | Vascular Diseases - prevention & control | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Multinational corporations | Mens health | Costs | Womens health | Cardiovascular disease | Acute coronary syndromes | Statins | Cholesterol | Index Medicus | Abridged Index Medicus
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3. Full Text Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis
by Casas, Juan P and Chua, Weiliang and Loukogeorgakis, Stavros and Vallance, Patrick and Smeeth, Liam and Hingorani, Aroon D and MacAllister, Raymond J
The Lancet (British edition), ISSN 0140-6736, 2005, Volume 366, Issue 9502, pp. 2026 - 2033
Biological and medical sciences | General aspects | Medical sciences | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Humans | Kidney Failure, Chronic - drug therapy | Diabetic Nephropathies - drug therapy | Renin-Angiotensin System - drug effects | Blood Pressure - drug effects | Antihypertensive Agents - therapeutic use | Randomized Controlled Trials as Topic | Research | Comparative analysis | Statistics | Angiotensin converting enzyme | Angiotensin II receptor blockers | Hypertension | Kidney diseases | Drug therapy | Health aspects | ACE inhibitors | Clinical trials | Diabetes | Index Medicus | Abridged Index Medicus
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4. Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: Population based cohort study using linked health records
by Bell, Steven and Daskalopoulou, Marina and Rapsomaniki, Eleni and George, Julie and Britton, Annie and Bobak, Martin and Casas, Juan P and Dale, Caroline E and Denaxas, Spiros and Shah, Anoop D and Hemingway, Harry
BMJ (Online), ISSN 0959-8146, 2017, Volume 356, p. j909
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Multivariate Analysis | Follow-Up Studies | Humans | Middle Aged | Proportional Hazards Models | Male | Alcohol Drinking - epidemiology | England - epidemiology | Sex Factors | Cardiovascular Diseases - epidemiology | Female | Primary Health Care | Electronic Health Records | Cohort Studies
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5. Full Text Unintended effects of statins from observational studies in the general population: Systematic review and meta-analysis
by Macedo, Ana F and Taylor, Fiona C and Casas, Juan P and Adler, Alma and Prieto-Merino, David and Ebrahim, Shah
BMC medicine, ISSN 1741-7015, 03/2014, Volume 12, Issue 1, pp. 51 - 51
Systematic review | Observational studies | Unintended effects | Statins | Meta-analysis | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Diabetes Mellitus - epidemiology | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Diabetes Mellitus - chemically induced | Treatment Outcome | Observational Studies as Topic - trends | Dementia - epidemiology | Dementia - prevention & control | Randomized Controlled Trials as Topic - trends | Population Surveillance - methods | Type 2 diabetes | Medical research | Medicine, Experimental | Eye diseases | Research | Comparative analysis | Dementia | Studies | Drug therapy | Cholesterol | Index Medicus
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6. Full Text Variants in the fetal genome near FLT1 are associated with risk of preeclampsia
by McGinnis, Ralph and Steinthorsdottir, Valgerdur and Williams, Nicholas O and Thorleifsson, Gudmar and Shooter, Scott and Hjartardottir, Sigrun and Bumpstead, Suzannah and Stefansdottir, Lilja and Hildyard, Lucy and Sigurdsson, Jon K and Kemp, John P and Silva, Gabriela B and Thomsen, Liv Cecilie V and Jääskeläinen, Tiina and Kajantie, Eero and Chappell, Sally and Kalsheker, Noor and Moffett, Ashley and Hiby, Susan and Lee, Wai Kwong and Padmanabhan, Sandosh and Simpson, Nigel A.B and Dolby, Vivien A and Staines-Urias, Eleonora and Engel, Stephanie M and Haugan, Anita and Trogstad, Lill and Svyatova, Gulnara and Zakhidova, Nodira and Najmutdinova, Dilbar and Dominiczak, Anna F and Gjessing, Håkon K and Casas, Juan P and Dudbridge, Frank and Walker, James J and Pipkin, Fiona Broughton and Thorsteinsdottir, Unnur and Geirsson, Reynir T and Lawlor, Debbie A and Iversen, Ann-Charlotte and Magnus, Per and Laivuori, Hannele and Stefansson, Kari and Morgan, Linda and FINNPEC Consortium and GOPEC Consortium and The FINNPEC Consortium and The GOPEC Consortium
Nature genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1255 - 1260
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Pre-Eclampsia - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Follow-Up Studies | Humans | Pregnancy Proteins - genetics | Genotype | Pregnancy | Female | Fetus | Polymorphism, Single Nucleotide | Genome, Human | Vascular Endothelial Growth Factor Receptor-1 - blood | Cohort Studies | Vascular Endothelial Growth Factor Receptor-1 - genetics | Genetic variation | Preeclampsia | Physiological aspects | Genetic aspects | Disease susceptibility | Research | Risk factors | Tyrosine | Hypertension | Nucleotide sequence | Susceptibility | Fetuses | Genomes | Pre-eclampsia | Gestation | Flt1 protein | Meta-analysis | Datasets | Studies | Consortia | Progeny | Parents & parenting | Offspring | Placenta | Birth weight | Protein-tyrosine kinase | Index Medicus
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7. Full Text Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection
by Pietzner, Maik and Wheeler, Eleanor and Carrasco-Zanini, Julia and Raffler, Johannes and Kerrison, Nicola D and Oerton, Erin and Auyeung, Victoria P W and Luan, Jian'an and Finan, Chris and Casas, Juan P and Ostroff, Rachel and Williams, Steve A and Kastenmüller, Gabi and Ralser, Markus and Gamazon, Eric R and Wareham, Nicholas J and Hingorani, Aroon D and Langenberg, Claudia
Nature communications, ISSN 2041-1723, 02/2021, Volume 12, Issue 1, pp. 845 - 845
Severe acute respiratory syndrome coronavirus 2 | Index Medicus
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8. Full Text Cochrane corner: text messaging to improve adherence to drugs for secondary prevention of cardiovascular disease
by Adler, Alma J and Casas, Juan P and Martin, Nicole and Free, Caroline and Perel, Pablo
Heart (British Cardiac Society), ISSN 1355-6037, 11/2018, Volume 104, Issue 22, pp. 1814 - 1816
coronary artery disease | global health | medication adherence | systemic review | ehealth/telemedicine/mobile health | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Text Messaging | Cardiovascular Diseases | Medication Adherence | Secondary Prevention | Cell Phone | Humans | Low income groups | Cardiovascular disease | Systematic review | Patient compliance | Text messaging | Index Medicus | Abridged Index Medicus
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9. Full Text Genetic architecture of host proteins involved in SARS-CoV-2 infection
by Pietzner, Maik and Wheeler, Eleanor and Carrasco-Zanini, Julia and Raffler, Johannes and Kerrison, Nicola D and Oerton, Erin and Auyeung, Victoria P. W and Luan, Jian'an and Finan, Chris and Casas, Juan P and Ostroff, Rachel and Williams, Steve A and Kastenmueller, Gabi and Ralser, Markus and Gamazon, Eric R and Wareham, Nicholas J and Hingorani, Aroon D and Langenberg, Claudia
Nature communications, ISSN 2041-1723, 12/2020, Volume 11, Issue 1, pp. 6397 - 6397
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | COVID-19 - virology | Host-Derived Cellular Factors - metabolism | Humans | Middle Aged | Gene Expression Regulation | ABO Blood-Group System - metabolism | Male | SARS-CoV-2 - physiology | Drug Delivery Systems | Proteins - genetics | Host-Pathogen Interactions - genetics | Aptamers, Peptide - blood | Blood Coagulation | Female | Internet | Aptamers, Peptide - metabolism | COVID-19 - genetics | Quantitative Trait Loci - genetics | Immune response | Nucleotide sequence | Severe acute respiratory syndrome | Viral diseases | Infections | Drug delivery | Coronaviruses | Drug development | Immunosuppressive agents | Proteins | Quantitative trait loci | Severe acute respiratory syndrome coronavirus 2 | COVID-19 | Genetic variance | Interrogation | Aptamers | Gene mapping | Deoxyribonucleic acid--DNA | Index Medicus
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10. Full Text Data-driven identification of ageing-related diseases from electronic health records
by Kuan, Valerie and Fraser, Helen C and Hingorani, Melanie and Denaxas, Spiros and Gonzalez-Izquierdo, Arturo and Direk, Kenan and Nitsch, Dorothea and Mathur, Rohini and Parisinos, Constantinos A and Lumbers, R Thomas and Sofat, Reecha and Wong, Ian C K and Casas, Juan P and Thornton, Janet M and Hemingway, Harry and Partridge, Linda and Hingorani, Aroon D
Scientific reports, ISSN 2045-2322, 02/2021, Volume 11, Issue 1, pp. 2938 - 2938
Learning algorithms | Aging | Cardiovascular diseases | Electronic health records | Electronic medical records | Morbidity | Age | Index Medicus
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11. Full Text Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis
by Holmes, Michael V and Lange, Leslie A and Palmer, Tom and Lanktree, Matthew B and North, Kari E and Almoguera, Berta and Buxbaum, Sarah and Chandrupatla, Hareesh R and Elbers, Clara C and Guo, Yiran and Hoogeveen, Ron C and Li, Jin and Li, Yun R and Swerdlow, Daniel I and Cushman, Mary and Price, Tom S and Curtis, Sean P and Fornage, Myriam and Hakonarson, Hakon and Patel, Sanjay R and Redline, Susan and Siscovick, David S and Tsai, Michael Y and Wilson, James G and van der Schouw, Yvonne T and FitzGerald, Garret A and Hingorani, Aroon D and Casas, Juan P and de Bakker, Paul I.W and Rich, Stephen S and Schadt, Eric E and Asselbergs, Folkert W and Reiner, Alex P and Keating, Brendan J
American journal of human genetics, ISSN 0002-9297, 02/2014, Volume 94, Issue 2, pp. 198 - 208
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Quantitative trait loci | Genetic research | Body mass index | Genetic aspects | Research | Metabolism | Cardiovascular disease | Lipoproteins | Diabetes | Cytokines | Risk assessment | Index Medicus
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