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by Kappos, Ludwig and Bar-Or, Amit and Cree, Bruce A C and Fox, Robert J and Giovannoni, Gavin and Gold, Ralf and Vermersch, Patrick and Arnold, Douglas L and Arnould, Sophie and Scherz, Tatiana and Wolf, Christian and Wallström, Erik and Dahlke, Frank and Achiron, Anat and Achtnichts, Lutz and Agan, Kadriye and Akman-Demir, Gulsen and Allen, Alison B and Antel, Jack P and Antiguedad, Alfredo Rodriguez and Apperson, Michelle and Applebee, Angela M and Ayuso, Guillermo Izquierdo and Baba, Masayuki and Bajenaru, Ovidiu and Balasa, Rodica and Balci, Belgin Petek and Barnett, Michael and Bass, Ann and Becker, Veit U and Bejinariu, Mihaela and Bergh, Florian Then and Bergmann, Arnfin and Bernitsas, Evanthia and Berthele, Achim and Bhan, Virender and Bischof, Felix and Bjork, Randall John and Blevins, Gregg and Boehringer, Matthias and Boerner, Thomas and Bonek, Robert and Bowen, James D and Bowling, Allen and Boyko, Alexey N and Boz, Cavit and Bracknies, Vera and Braune, Stefan and Brescia Morra, Vincenzo and Brochet, Bruno and Brola, Waldemar and Brownstone, Paul Kenneth and Brozman, Miroslav and Brunet, Donald and Buraga, Ioan and Burnett, Margaret and Buttmann, Mathias and Butzkueven, Helmut and Cahill, Jonathan and Calkwood, Jonathan C and Camu, William and Cascione, Mark and Castelnovo, Giovani and Centonze, Diego and Cerqueira, Joao and Chan, Andrew and Cimprichova, Andrea and Cohan, Stanley and Comi, Giancarlo and Conway, Jill and Cooper, Joanna A and Corboy, John and Correale, Jorge and Costell, Brian and Cottrell, David A and Coyle, Patricia K and Craner, Matthew and Cui, Liying and Cunha, Luis and Czlonkowska, Anna and da Silva, Ana Martins and de Sa, Joao and de Seze, Jérôme and Debouverie, Marc and Debruyne, Jan and Decoo, Danny and Defer, Gilles and Derfuss, Tobias and Deri, Norma H and Dihenia, Bhupesh and Dioszeghy, Peter and Donath, Vladimir and Dubois, Benedicte and Duddy, Martin and Duquette, Pierre and Edan, Gilles and Efendi, Husnu and Elias, Stanton and Emrich, Peter J and Estruch, Bonaventura Casanova and ... and EXPAND Clinical Investigators and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
The Lancet, ISSN 0140-6736, 03/2018, Volume 391, Issue 10127, pp. 1263 - 1273
Journal Article
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 05/2017, Volume 88, Issue 5, pp. e1 - e1
Objectives To preliminarily assess annualised relapse rate (ARR) at 144 weeks among patients with relapsing multiple sclerosis (RMS) who received ocrelizumab... 
SURGERY | PSYCHIATRY | CLINICAL NEUROLOGY
Journal Article
Gastroenterology, ISSN 0016-5085, 03/2018, Volume 154, Issue 4, pp. 1066 - 1079.e5
Cholangiocarcinomas (CCA) are resistant to chemotherapy, so new therapeutic agents are needed. We performed a screen to identify small-molecule compounds that... 
Organoid | Bile Duct Cancer | DNAJB5 | AUY922 | BILIARY-TRACT CANCER | INTRAHEPATIC CHOLANGIOCARCINOMA | ADVANCED SOLID TUMORS | PANCREATIC-CANCER | ACQUIRED-RESISTANCE | I DOSE-ESCALATION | TYROSINE KINASE INHIBITORS | HSP90 INHIBITORS | PROSTATE-CANCER | GASTROENTEROLOGY & HEPATOLOGY | MICRORNA EXPRESSION | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Cholangiocarcinoma - metabolism | Dose-Response Relationship, Drug | Transfection | Organoids | Time Factors | Antineoplastic Agents - pharmacology | HSP90 Heat-Shock Proteins - genetics | Bile Duct Neoplasms - genetics | Tumor Cells, Cultured | Nuclear Proteins - genetics | Bile Duct Neoplasms - drug therapy | Cell Survival - drug effects | HSP40 Heat-Shock Proteins - metabolism | Bile Duct Neoplasms - metabolism | HSP40 Heat-Shock Proteins - genetics | Isocitrate Dehydrogenase - genetics | Transcription Factors - genetics | Mice, SCID | Xenograft Model Antitumor Assays | Cholangiocarcinoma - pathology | Drug Resistance, Neoplasm - genetics | Animals | Cholangiocarcinoma - drug therapy | Signal Transduction - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Cell Line, Tumor | Cholangiocarcinoma - genetics | HSP90 Heat-Shock Proteins - metabolism | Mice, Inbred NOD | MicroRNAs - genetics | Bile Duct Neoplasms - pathology | Mutation | Index Medicus | Abridged Index Medicus | FFPE, formalin-fixed paraffin-embedded | FGFR, fibroblast growth factor receptor | WT, wild type | PDO, patient-derived organoid | GI, growth inhibition | miRNA, microRNA | HTS, high-throughput screen | DMSO, dimethyl sulfoxide | HSP, heat shock protein | iCCA, intrahepatic cholantiocarcinoma | CCA, cholangiocarcinoma
Journal Article
BMC Neurology, ISSN 1471-2377, 01/2012, Volume 12, Issue 1, pp. 154 - 154
A total of 129 patients were included in the intent-to-treat analysis. Mean (standard deviation) change in VAS diary pain score was not significantly different... 
Multiple sclerosis | Care and treatment | Interferon beta-1b | Pain | Interferon beta-1a | Interferon beta | Albumin | Biological response modifiers | Comparative analysis | Pharmaceutical industry | Viral antigens | Neurology | Neurosciences | Cytokines | Reforms | Drug dosages | Patients
Journal Article
by Bultet, Lisandra Aguilar and Aguilar-Rodríguez, José and Ahrens, Christian H and Ahrné, Erik Lennart and Ai, Ni and Aimo, Lucila and Akalin, Altuna and Aleksiev, Tyanko and Alocci, Davide and Altenhoff, Adrian and Alves, Isabel and Ambrosini, Giovanna and Pedone, Pascale Anderle and Angelino, Paolo and Anisimova, Maria and Appel, Ron and Argoud-Puy, Ghislaine and Arnold, Konstantin and Arpat, Bulak and Artimo, Panu and Ascencao, Kelly and Auchincloss, Andrea and Axelsen, Kristian and Gerritsen, Vivienne Baillie and Bairoch, Amos and Bansal, Parit and Baratin, Delphine and Barbato, Alessandro and Barbié, Valérie and Barras, David and Barreiro, Maria and Barret, Sophie and Bastian, Frederic and Neto, Teresamanuela Batista and Baudis, Michael and Beaudoing, Emmanuel and Beckmann, Jacques S and Bekkar, Amel Kawter and Ben Hamida Cammoun, Leila and Benmohammed, Sara and Bernard, Madeleine and Bertelli, Claire and Bertoni, Martino and Bienert, Stefan and Bignucolo, Olivier and Bilbao, Aivett and Bilican, Adem and Blank, Diana and Blatter, Marie-Claude and Blum, Lorenz and Bocquet, Jocelyne and Boeckmann, Brigitte and Bolleman, Jerven Tjalling and Bordoli, Lorenza and Bosshard, Lars and Bouchet, Gerard and Bougueleret, Lydie and Boutet, Emmanuel and Bovigny, Christophe and Bratulic, Sinisa and Breuza, Lionel and Bridge, Alan James and Britan, Aurore and Brito, Francisco and Frazão, Josias Brito and Bruggmann, Rémy and Bucher, Philipp and Burdet, Frédéric and Burger, Lukas and Cabello, Elena Maria and Gomez, Ruben Martin Cabezon and Calderon, Sandra and Cannarozzi, Gina and Carl, Sarah and Casas, Cristina Casals and Catherinet, Sebastien and Périer, Rouayda Cavin and Charpilloz, Christophe and Chaskar, Prasad Datatray and Chen, Weihua and Pepe, Anush Chiappino and Chopard, Bastien and Chu, Hoi Yee and Civic, Natacha and Claassen, Manfred and Clottu, Sylvie and Colombo, Martino and Cosandier, Isabelle and Coudert, Elisabeth and Crespo, Isaac and Creus, Marc and Cuche, Béatrice and Cuendet, Michel A and Cusin, Isabelle and Daga, Neha and Daina, Antoine and Dauvillier, Jér Ôme and David, Fabrice and Davydov, Iakov and De Sa Ricca Manadelo Ferreira, Mariana and ... and SIB Swiss Inst Bioinformatics
Nucleic Acids Research, ISSN 0305-1048, 2016, Volume 44, Issue 1, pp. D27 - D37
The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the... 
PROTEIN MODELS | QUALITY | REGULATORY SITES | LANDSCAPE | KNOWLEDGEBASE | ARCHIVE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPOSITORY | EXPRESSION DATA | TOOLS | PREDICTION | Index Medicus | Database Issue
Journal Article
Therapeutic Advances in Neurological Disorders, ISSN 1756-2856, 5/2018, Volume 11, pp. 1756286418774338 - 1756286418774338
Objective: In relapsing–remitting multiple sclerosis (RRMS), suboptimal adherence to injectable disease-modifying therapies (iDMTs; interferon β-1a/b,... 
adherence | fingolimod | multiple sclerosis | disease-modifying therapy | glatiramer acetate | interferon | retention | randomized controlled trial | MEDICATION | MULTICENTER | ORAL FINGOLIMOD | PERSISTENCE | GREY-MATTER ATROPHY | CLINICAL NEUROLOGY | PSYCHOMETRIC EVALUATION | DISEASE-MODIFYING THERAPIES | INTERFERON BETA-1A | SATISFACTION QUESTIONNAIRE MSQ
Journal Article
Therapeutic Advances in Neurological Disorders, 05/2018, Volume 11
Objective: In relapsing–remitting multiple sclerosis (RRMS), suboptimal adherence to injectable disease-modifying therapies (iDMTs; interferon β-1a/b,... 
Journal Article