X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
oncology (16) 16
index medicus (15) 15
colorectal cancer (12) 12
humans (12) 12
colorectal neoplasms - drug therapy (11) 11
colorectal neoplasms - genetics (10) 10
female (7) 7
metastasis (7) 7
aged (6) 6
article (6) 6
cancer (6) 6
egfr (6) 6
male (6) 6
middle aged (6) 6
mutation (6) 6
acquired-resistance (5) 5
adult (5) 5
colorectal neoplasms - pathology (5) 5
tumors (5) 5
aged, 80 and over (4) 4
animals (4) 4
chemotherapy (4) 4
clinical trials (4) 4
dna methylation (4) 4
drug resistance, neoplasm (4) 4
drug resistance, neoplasm - genetics (4) 4
gene copy number (4) 4
medicine & public health (4) 4
therapy (4) 4
analysis (3) 3
antibodies, monoclonal - therapeutic use (3) 3
antineoplastic agents - pharmacology (3) 3
antineoplastic combined chemotherapy protocols - therapeutic use (3) 3
biomarkers (3) 3
care and treatment (3) 3
cell biology (3) 3
cetuximab (3) 3
colorectal neoplasms - metabolism (3) 3
deoxyribonucleic acid--dna (3) 3
digestive system diseases (3) 3
drug resistance (3) 3
epidermal growth factor (3) 3
genetic aspects (3) 3
hematology, oncology and palliative medicine (3) 3
kras (3) 3
methylation (3) 3
monoclonal antibodies (3) 3
mutation - genetics (3) 3
mutations (3) 3
neoplasm metastasis (3) 3
panitumumab (3) 3
patients (3) 3
phase-ii (3) 3
pik3ca mutations (3) 3
prognosis (3) 3
proto-oncogene proteins p21 (3) 3
proto-oncogene proteins p21 - genetics (3) 3
receptor, epidermal growth factor - antagonists & inhibitors (3) 3
receptor, epidermal growth factor - genetics (3) 3
research (3) 3
resistance (3) 3
xenograft model antitumor assays (3) 3
amplification (2) 2
antibodies, monoclonal - pharmacology (2) 2
antineoplastic agents - therapeutic use (2) 2
antineoplastic agents, alkylating - therapeutic use (2) 2
biochemistry & molecular biology (2) 2
biomedicine general (2) 2
breast (2) 2
breast-cancer (2) 2
cancer patients (2) 2
cancer therapies (2) 2
clonal evolution (2) 2
colon (2) 2
colon-cancer (2) 2
colorectal carcinoma (2) 2
colorectal neoplasms - diagnosis (2) 2
càncer colorectal (2) 2
dacarbazine - therapeutic use (2) 2
digital pcr (2) 2
disease-free survival (2) 2
dna modification methylases - genetics (2) 2
drug resistance, neoplasm - drug effects (2) 2
epigenesis (2) 2
epigenetics (2) 2
epigènesi (2) 2
expression (2) 2
gene (2) 2
gene dosage - genetics (2) 2
gene expression (2) 2
genetic research (2) 2
genètica mèdica (2) 2
glioblastoma (2) 2
health aspects (2) 2
heterogeneity (2) 2
hypermethylation (2) 2
immunohistochemistry (2) 2
inactivation (2) 2
inhibitor cetuximab (2) 2
irinotecan (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 6, pp. 738 - 746
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 263 - 267
Colorectal cancer is the third most common cancer worldwide, with 1.2 million patients diagnosed annually. In late-stage colorectal cancer, the most commonly... 
PANITUMUMAB | THERAPY | MULTIDISCIPLINARY SCIENCES | SEQUENCE | ACQUIRED-RESISTANCE | SOMATIC MUTATION | IDENTIFICATION | GENE COPY NUMBER | ACTIVATING MUTATIONS | BREAST | INSIGHTS | Receptor, Epidermal Growth Factor - genetics | Receptor, ErbB-2 - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Genomics | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Cetuximab - therapeutic use | Molecular Targeted Therapy | Receptor, Fibroblast Growth Factor, Type 1 - genetics | MAP Kinase Kinase 1 - genetics | Colorectal Neoplasms - drug therapy | Female | Antineoplastic Agents - pharmacology | Insulin Receptor Substrate Proteins - genetics | Colorectal Neoplasms - metabolism | Antibodies, Monoclonal - pharmacology | Cetuximab - pharmacology | DNA Copy Number Variations - genetics | Mutation - genetics | Genome, Human - genetics | Receptor, Epidermal Growth Factor - chemistry | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Exome - genetics | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Colorectal cancer | Drug metabolism | Genetic aspects | Identification and classification | Health aspects | Proteins | Epidermal growth factor | Genes | Clinical trials | Mutation | Kinases | Cancer therapies | Tumors | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2015, Volume 21, Issue 7, pp. 795 - 801
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 2013, Volume 3, Issue 6, pp. 658 - 673
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 2014, Volume 106, Issue 1, pp. djt322 - djt322
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2017, Volume 23, Issue 14, pp. 3657 - 3666
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2016, Volume 71, pp. 43 - 50
Abstract Background O(6)-methylguanine-DNA-methyltransferase (MGMT) is a repair protein, and its deficiency makes tumours more susceptible to the cytotoxic... 
Hematology, Oncology and Palliative Medicine | Immunohistochemistry | DNA methylation | Alkylating agent | Digital PCR | MGMT | Metastatic colorectal cancer | HYPERMETHYLATION | CPG ISLAND | PHASE-II | TEMOZOLOMIDE | INACTIVATION | GLIOBLASTOMA | BENEFIT | ONCOLOGY | MUTATIONS | CLINICAL-RESPONSE | O-6-METHYLGUANINE DNA METHYLTRANSFERASE | Multivariate Analysis | Predictive Value of Tests | Dacarbazine - therapeutic use | Colorectal Neoplasms - genetics | Humans | Middle Aged | O-Methylguanine-DNA Methyltransferase - metabolism | Male | DNA Methylation - genetics | Promoter Regions, Genetic - genetics | Polymerase Chain Reaction - methods | Antineoplastic Agents, Alkylating - therapeutic use | O-Methylguanine-DNA Methyltransferase - genetics | DNA Modification Methylases - genetics | Colorectal Neoplasms - drug therapy | Dacarbazine - analogs & derivatives | Survival Analysis | Aged, 80 and over | Adult | Colorectal Neoplasms - secondary | Female | Aged | Retrospective Studies | Care and treatment | Cancer patients | Analysis | Transferases | Colorectal cancer | Metastasis | Methylation | Colorectal carcinoma | Clinical trials | Cytotoxicity | Paraffin | Alkylation | Metastases | O6-methylguanine-DNA methyltransferase | Dacarbazine | Deoxyribonucleic acid--DNA | Medical research | Test procedures | Methylguanine | Alkylating agents | Data processing | Protein deficiency | Patients | Survival | Polymerase chain reaction | DNA methyltransferase | Temozolomide | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2013, Volume 19, Issue 8, pp. 2265 - 2272
Journal Article