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American Journal of Hypertension, ISSN 0895-7061, 2019, Volume 32, Issue 6, pp. 597 - 604
Previously, we demonstrated that obese mice have marked elevations in systemic concentrations of angiotensin II (AngII). Drugs that inhibit the... 
Hypertension | Obesity | Angiotensin | AT1R | Blood pressure | Islets | Diabetes | Insulin
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 03/2012, Volume 302, Issue 6, pp. H1219 - H1230
Putnam K, Shoemaker R, Yiannikouris F, Cassis LA. The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and... 
Angiotensinogen | Obesity | Hypercholesterolemia | Glucose | Insulin | glucose | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | insulin | ABDOMINAL AORTIC-ANEURYSMS | II TYPE-1 RECEPTOR | PROXIMAL TUBULAR CELLS | CONVERTING ENZYME-INHIBITORS | DIET-INDUCED OBESITY | angiotensinogen | hypercholesterolemia | END-POINT REDUCTION | INSULIN-RESISTANCE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | E-DEFICIENT MICE | NF-KAPPA-B | obesity | Blood Pressure | Dyslipidemias - drug therapy | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Insulin Resistance | Glucose Metabolism Disorders - drug therapy | Homeostasis | Hypertension - drug therapy | Lipid Metabolism | Metabolic Syndrome - metabolism | Glucose Metabolism Disorders - physiopathology | Metabolic Syndrome - drug therapy | Hypertension - physiopathology | Hypertension - metabolism | Animals | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Glucose Metabolism Disorders - metabolism | Metabolic Syndrome - physiopathology | Dyslipidemias - metabolism | Renin-Angiotensin System - drug effects | Blood Glucose - metabolism | Dyslipidemias - physiopathology | Glucose metabolism | Dyslipidemias | Physiological aspects | Development and progression | Research | Metabolic syndrome X | Renin-angiotensin system | Health aspects | Reviews
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, ISSN 1079-5642, 03/2004, Volume 24, Issue 3, pp. 429 - 434
ABSTRACT—Many mouse models of abdominal aortic aneurysms have been developed that use a diverse array of methods for producing the disease, including genetic... 
Aneurysms | Mice | ACCELERATED ATHEROSCLEROSIS | VASCULAR-LESIONS | ANGIOTENSIN-II | HYPERCHOLESTEROLEMIA | mice | PERIARTERIAL APPLICATION | ARTERIOSCLEROSIS | TISSUE INHIBITOR | PERIPHERAL VASCULAR DISEASE | LDL RECEPTOR-DEFICIENT | HEMATOLOGY | EXPRESSION | aneurysms | TRANSGENIC MICE | Mice, Knockout - genetics | Aortic Aneurysm, Abdominal - chemically induced | Hyperlipidemias - genetics | Matrix Metalloproteinases - genetics | Angiotensin II - genetics | Aortic Aneurysm, Abdominal - prevention & control | Apolipoproteins E - deficiency | Species Specificity | Humans | Matrix Metalloproteinases - deficiency | Nitric Oxide Synthase - genetics | Aortic Aneurysm, Abdominal - blood | Mice, Mutant Strains - genetics | Nitric Oxide Synthase Type II | Renin - genetics | Pancreatic Elastase - toxicity | Receptors, LDL - deficiency | Female | Models, Animal | Angiotensin II - toxicity | Protease Inhibitors - therapeutic use | Extracellular Matrix Proteins - metabolism | Hyperlipidemias - complications | Disease Models, Animal | Calcium Chloride - toxicity | Receptors, LDL - genetics | Genetic Predisposition to Disease | Extracellular Matrix Proteins - genetics | Nitric Oxide Synthase Type III | Aortic Aneurysm, Abdominal - genetics | Cholesterol - metabolism | Animals | Genetic Engineering | Nitric Oxide Synthase - deficiency | Aortic Aneurysm, Abdominal - physiopathology | Apolipoproteins E - genetics | Matrix Metalloproteinase Inhibitors | Matrix Metalloproteinases - physiology
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2018, Volume 38, Issue 2, pp. 292 - 303
There are many differences in arterial diseases between men and women, including prevalence, clinical manifestations, treatments, and prognosis. The new policy... 
atherosclerosis | animal models | peripheral arterial disease | aortic aneurysms | INTIMA-MEDIA THICKNESS | ATHEROSCLEROTIC LESIONS | BRACHIOCEPHALIC ARTERY | RISK-FACTORS | MYOCARDIAL-INFARCTION | CAROTID-ARTERY | INTERNATIONAL REGISTRY | ABDOMINAL AORTIC-ANEURYSM | PERIPHERAL VASCULAR DISEASE | LDL RECEPTOR-DEFICIENT | HEMATOLOGY | GENDER-DIFFERENCES
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1614, pp. 69 - 73
Journal Article
Circulation, ISSN 0009-7322, 12/2004, Volume 110, Issue 25, pp. 3849 - 3857
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 6/2008, Volume 116, Issue 6, pp. 761 - 768
Background: Obesity, an inflammatory condition linked to cardiovascular disease, is associated with expansion of adipose tissue. Highly prevalent coplanar... 
Adipose tissues | Obesity | Serum cholesterol | Messenger RNA | Body weight | Liver | Atherosclerosis | Adipocytes | Research | Dosage | Vehicles | Adipocyte differentiation | Atyl hydrocarbon receptor | Ectopic lipid deposition | Polychlorinated bipheyl | METABOLIC SYNDROME | adipocyte differentiation | PERSISTENT ORGANIC POLLUTANTS | polychlorinated biphenyl | ADIPOSE DIFFERENTIATION | NONDIABETIC ADULTS | aryl hydrocarbon receptor | DIABETES-MELLITUS | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | ectopic lipid deposition | SERUM CONCENTRATIONS | INDUCED OXIDATIVE STRESS | INSULIN-RESISTANCE | 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN TCDD | TOXICOLOGY | VASCULAR ENDOTHELIAL-CELLS | obesity | Gene Expression - drug effects | Body Weight - drug effects | Adipocytes - cytology | Male | Weight Gain - physiology | Adipocytes - drug effects | PPAR gamma - metabolism | Inflammation Mediators - metabolism | Weight Gain - drug effects | Atherosclerosis - pathology | Obesity - chemically induced | Cytokines - metabolism | Atherosclerosis - chemically induced | Mice, Inbred C57BL | Receptors, Aryl Hydrocarbon - genetics | Adipokines - metabolism | 3T3-L1 Cells | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Aryl Hydrocarbon - physiology | Mice, Knockout | Obesity - pathology | Glycerolphosphate Dehydrogenase - metabolism | Animals | Polychlorinated Biphenyls - toxicity | Cell Differentiation - drug effects | Mice | Body Weight - physiology | Index Medicus
Journal Article
Journal of Vascular Surgery, ISSN 0741-5214, 2019
Clinical Relevance: Results from this study suggest a novel mode of intervening in the renin-angiotensin system to treat vascular diseases, namely, by... 
Mas receptor | Angiotensin-(1-7) | Aneurysm | Atherosclerosis | Rupture
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 03/2017, Volume 312, Issue 3, pp. H459 - H468
Journal Article
Hypertension research : official journal of the Japanese Society of Hypertension, ISSN 0916-9636, 11/2016, Volume 39, Issue 11, p. 827
This corrects the article DOI: 10.1038/hr.2016.17 
Journal Article
Hypertension, ISSN 0194-911X, 11/2014, Volume 64, Issue Suppl_1 Suppl 1, pp. A037 - A037
ObjectiveDiet-induced obesity promotes type 2 diabetes (T2D). Drugs that inhibit the renin-angiotensin system (RAS) have been demonstrated in clinical trials... 
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology: Journal of the American Heart Association, ISSN 1079-5642, 09/2003, Volume 23, Issue 9, pp. 1621 - 1626
Journal Article