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1. Full Text Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial
by Petrylak, Daniel P and de Wit, Ronald and Chi, Kim N and Drakaki, Alexandra and Sternberg, Cora N and Nishiyama, Hiroyuki and Castellano, Daniel and Hussain, Syed and Fléchon, Aude and Bamias, Aristotelis and Yu, Evan Y and van der Heijden, Michiel S and Matsubara, Nobuaki and Alekseev, Boris and Necchi, Andrea and Géczi, Lajos and Ou, Yen-Chuan and Coskun, Hasan Senol and Su, Wen-Pin and Hegemann, Miriam and Percent, Ivor J and Lee, Jae-Lyun and Tucci, Marcello and Semenov, Andrey and Laestadius, Fredrik and Peer, Avivit and Tortora, Giampaolo and Safina, Sufia and del Muro, Xavier Garcia and Rodriguez-Vida, Alejo and Cicin, Irfan and Harputluoglu, Hakan and Widau, Ryan C and Liepa, Astra M and Walgren, Richard A and Hamid, Oday and Zimmermann, Annamaria H and Bell-McGuinn, Katherine M and Powles, Thomas and Wong, Suet-Lai Shirley and Tan, Thean Hsiang and Hovey, Elizabeth Jane and Clay, Timothy Dudley and Ng, Siobhan Su Wan and Rutten, Annemie and Machiels, Jean-Pascal and Dumez, Herlinde and Cheng, Susanna Yee-Shan and Chi, Kim Nguyen and Ferrario, Cristiano and Sengeloev, Lisa and Jensen, Niels Viggo and Thibault, Constance and Laguerre, Brigitte and Laestadius, Fredrik and Joly, Florence and Flechon, Aude and Culine, Stéphane and Becht, Catherine and Niegisch, Günter and Stöckle, Michael and Grimm, Marc-Oliver and Gakis, Georgios and Schultze-Seemann, Wolfgang and Kalofonos, Haralambos and Mavroudis, Dimitrios and Papandreou, Christos and Karavasilis, Vasilis and Bamias, Aristotelis and Révész, Janos and Geczi, Lajos and Rosenbaum, Eli and Leibowitz-Amit, Raya and Kejzman, Daniel and Peer, Avivit and Sarid, David and Scagliotti, Giorgio Vittorio and Sternberg, Cora N and Tortora, Giampaolo and Bracarda, Sergio and Necchi, Andrea and Massari, Francesco and Osawa, Takahiro and Miyajima, Naoto and Shinohara, Nobuo and Fukuta, Fumimasa and Ohyama, Chikara and Obara, Wataru and Yamashita, Shinichi and Tomita, Yoshihiko and Kawai, Koji and Fukasawa, Satoshi and Matsubara, Nobuaki and Oyama, Masafumi and Yonese, Junji and Nagata, Masayoshi and Uemura, Motohide and Nishimura, Kazuo and Kawakita, Mutsushi and Tsunemori, Hiroyuki and ... and RANGE study investigators and RANGE Study Investigators
The Lancet (British edition), ISSN 0140-6736, 11/2017, Volume 390, Issue 10109, pp. 2266 - 2277
BREAST-CANCER | BLADDER-CANCER | LUNG-CANCER | 2ND-LINE THERAPY | TRANSITIONAL-CELL-CARCINOMA | FOLLOW-UP | OPEN-LABEL | FACTOR RECEPTOR-2 | II TRIAL | ENDOTHELIAL GROWTH-FACTOR | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Carcinoma, Transitional Cell - mortality | Prognosis | Humans | Middle Aged | Male | Neoplasm Invasiveness - pathology | Urinary Bladder Neoplasms - pathology | Adult | Female | Urinary Bladder Neoplasms - mortality | Double-Blind Method | Risk Assessment | Docetaxel | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Urinary Bladder Neoplasms - drug therapy | Disease-Free Survival | Taxoids - administration & dosage | Carcinoma, Transitional Cell - pathology | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Internationality | Neoadjuvant Therapy - methods | Carcinoma, Transitional Cell - drug therapy | Survival Analysis | Aged | Neoplasm Staging | Antimitotic agents | Care and treatment | Carcinoma | Analysis | Clinical trials | Product development | Metastasis | Antineoplastic agents | Cancer | Cytotoxicity | Oncology | Patients | Cancer therapies | Evidence-based medicine | Metastases | Angiogenesis | Chemotherapy | Platinum | Medical prognosis | Ligands | Clinical medicine | Urothelial carcinoma | Vascular endothelial growth factor | Apoptosis | Index Medicus | Abridged Index Medicus
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2. Full Text Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
by Rosenberg, Jonathan E, Dr and Hoffman-Censits, Jean, MD and Powles, Tom, Prof and van der Heijden, Michiel S, Prof and Balar, Arjun V, MD and Necchi, Andrea, MD and Dawson, Nancy, Prof and O'Donnell, Peter H, MD and Balmanoukian, Ani, MD and Loriot, Yohann, MD and Srinivas, Sandy, MD and Retz, Margitta M, Prof and Grivas, Petros, MD and Joseph, Richard W, MD and Galsky, Matthew D, MD and Fleming, Mark T, MD and Petrylak, Daniel P, Prof and Perez-Gracia, Jose Luis, MD and Burris, Howard A, MD and Castellano, Daniel, MD and Canil, Christina, MD and Bellmunt, Joaquim, MD and Bajorin, Dean, Prof and Nickles, Dorothee, PhD and Bourgon, Richard, PhD and Frampton, Garrett M, PhD and Cui, Na, PhD and Mariathasan, Sanjeev, PhD and Abidoye, Oyewale, MD and Fine, Gregg D, MD and Dreicer, Robert, Prof
The Lancet (British edition), ISSN 0140-6736, 2016, Volume 387, Issue 10031, pp. 1909 - 1920
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Humans | Middle Aged | Immunoglobulins, Intravenous - administration & dosage | Male | Response Evaluation Criteria in Solid Tumors | Antineoplastic Agents - administration & dosage | Cisplatin - administration & dosage | Neoplasm Metastasis | Antibodies, Monoclonal, Humanized - administration & dosage | Urologic Neoplasms - drug therapy | Urologic Neoplasms - genetics | Aged, 80 and over | Adult | Female | Drug Administration Schedule | Carboplatin - administration & dosage | Treatment Outcome | Mutation - genetics | B7-H1 Antigen - immunology | Disease Progression | B7-H1 Antigen - antagonists & inhibitors | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Infusions, Intravenous | Medical colleges | Care and treatment | Chemotherapy | Carcinoma | Clinical trials | Monoclonal antibodies | Metastasis | Research institutes | Cancer | Analysis | Immunotherapy | Medical prognosis | Ligands | Genomes | Mutation | Gene expression | Cancer therapies | Bladder cancer | Tumors | Index Medicus | Abridged Index Medicus
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3. Full Text Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity
by Mamessier, Emilie and Sylvain, Aude and Thibult, Marie-Laure and Houvenaeghel, Gilles and Jacquemier, Jocelyne and Castellano, Rémy and Gonçalves, Anthony and André, Pascale and Romagné, François and Thibault, Gilles and Viens, Patrice and Birnbaum, Daniel and Bertucci, François and Moretta, Alessandro and Olive, Daniel
The Journal of clinical investigation, ISSN 0021-9738, 09/2011, Volume 121, Issue 9, pp. 3609 - 3622
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Mammary Glands, Human - cytology | Self Tolerance - immunology | Breast Neoplasms - immunology | Neoplasm Invasiveness | Humans | Middle Aged | Tumor Microenvironment | Receptors, Natural Killer Cell - immunology | Disease Progression | Killer Cells, Natural - cytology | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Interferon-gamma - immunology | K562 Cells | Killer Cells, Natural - immunology | Female | Mammary Glands, Human - physiology | Tumor Cells, Cultured | Cytotoxicity, Immunologic - immunology | Receptors, Natural Killer Cell - genetics | Development and progression | Killer cells | Genetic aspects | Breast cancer | Cellular immunity | Cancer cells | Index Medicus | Abridged Index Medicus | Life Sciences | Immunology | Immunotherapy | Cancer
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4. Full Text Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex
by Castellano, Brian M and Thelen, Ashley M and Moldavski, Ofer and Feltes, McKenna and Van Der Welle, Reini E.N and Mydock-McGrane, Laurel and Jiang, Xuntian and Van Eijkeren, Robert J and Davis, Oliver B and Louie, Sharon M and Perera, Rushika M and Covey, Douglas F and Nomura, Daniel K and Ory, Daniel S and Zoncu, Roberto
Science (American Association for the Advancement of Science), ISSN 0036-8075, 03/2017, Volume 355, Issue 6331, pp. 1306 - 1311
Cricetulus | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Cholesterol, HDL - metabolism | Humans | Nuclear Proteins - metabolism | Cholesterol - metabolism | Amino Acid Transport Systems - metabolism | Amino Acid Motifs | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | Animals | Carrier Proteins - metabolism | Lysosomes - metabolism | Biological Transport | HEK293 Cells | Amino Acid Transport Systems - genetics | Fibroblasts | Mice | Enzyme Activation | Mutation | CHO Cells | TOR protein | Niemann-Pick disease | Diabetes mellitus | Lipids | Amino acids | Rapamycin | Metabolism | Kinases | Cholesterol | Proteins | Diet | Sterols | Arginine | Protein kinase | Nutrients | Npc1 protein | Protein transport | Cancer | Index Medicus | Lysosomes | Activation | Transporter
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5. Full Text Current knowledge on diagnosis and staging of neuroendocrine tumors
by Öberg, Kjell and Castellano, Daniel
Cancer and metastasis reviews, ISSN 0167-7659, 3/2011, Volume 30, Issue S1, pp. 3 - 7
Molecular imaging | GEP-NETs | TNM staging | Biomedicine | Biomarkers | Oncology | Cancer Research | Neuroendocrine tumor | WHO classification | Biomedicine general | Life Sciences & Biomedicine | Science & Technology | Neuroendocrine Tumors - pathology | Neuroendocrine Tumors - classification | Humans | Molecular Imaging | Neuroendocrine Tumors - diagnosis | Neoplasm Staging | Biomarkers, Tumor | Diagnosis | PET imaging | Histochemistry | Public health | Cancer | Index Medicus
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6. Full Text Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study
by Kuderer, Nicole M and Choueiri, Toni K and Shah, Dimpy P and Shyr, Yu and Rubinstein, Samuel M and Rivera, Donna R and Shete, Sanjay and Hsu, Chih-Yuan and Desai, Aakash and de Lima Lopes, Gilberto and Grivas, Petros and Painter, Corrie A and Peters, Solange and Thompson, Michael A and Bakouny, Ziad and Batist, Gerald and Bekaii-Saab, Tanios and Bilen, Mehmet A and Bouganim, Nathaniel and Larroya, Mateo Bover and Castellano, Daniel and Del Prete, Salvatore A and Doroshow, Deborah B and Egan, Pamela C and Elkrief, Arielle and Farmakiotis, Dimitrios and Flora, Daniel and Galsky, Matthew D and Glover, Michael J and Griffiths, Elizabeth A and Gulati, Anthony P and Gupta, Shilpa and Hafez, Navid and Halfdanarson, Thorvardur R and Hawley, Jessica E and Hsu, Emily and Kasi, Anup and Khaki, Ali R and Lemmon, Christopher A and Lewis, Colleen and Logan, Barbara and Masters, Tyler and McKay, Rana R and Mesa, Ruben A and Morgans, Alicia K and Mulcahy, Mary F and Panagiotou, Orestis A and Peddi, Prakash and Pennell, Nathan A and Reynolds, Kerry and Rosen, Lane R and Rosovsky, Rachel and Salazar, Mary and Schmidt, Andrew and Shah, Sumit A and Shaya, Justin A and Steinharter, John and Stockerl-Goldstein, Keith E and Subbiah, Suki and Vinh, Donald C and Wehbe, Firas H and Weissmann, Lisa B and Wu, Julie Tsu-Yu and Wulff-Burchfield, Elizabeth and Xie, Zhuoer and Yeh, Albert and Yu, Peter P and Zhou, Alice Y and Zubiri, Leyre and Mishra, Sanjay and Lyman, Gary H and Rini, Brian I and Warner, Jeremy L and Abidi, Maheen and Acoba, Jared D and Agarwal, Neeraj and Ahmad, Syed and Ajmera, Archana and Altman, Jessica and Angevine, Anne H and Azad, Nilo and Bar, Michael H and Bardia, Aditya and Barnholtz-Sloan, Jill and Barrow, Briana and Bashir, Babar and Belenkaya, Rimma and Berg, Stephanie and Bernicker, Eric H and Bestvina, Christine and Bishnoi, Rohit and Boland, Genevieve and Bonnen, Mark and Bouchard, Gabrielle and Bowles, Daniel W and Busser, Fiona and Cabal, Angelo and Caimi, Paolo and Carducci, Theresa and Casulo, Carla and ... and COVID-19 and Cancer Consortium and COVID-19 Canc Consortium
The Lancet (British edition), ISSN 0140-6736, 06/2020, Volume 395, Issue 10241, pp. 1907 - 1918
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Cancer patients | Research | Oncology, Experimental | Cancer | Pandemics | Laboratories | Identification methods | Health services | Viral diseases | Sex | Azithromycin | Oncology | Infections | Malignancy | Cancer therapies | Risk factors | Consortia | COVID-19 | Variables | Databases | Surgery | Remission | Population | Diagnosis | Age | Obesity | Ventilators | Data analysis | Statistical analysis | Hematology | Mortality | Medical treatment | Severe acute respiratory syndrome | Regression analysis | Coronaviruses | Risk analysis | Minority & ethnic groups | Patients | Cancer surgery | Severe acute respiratory syndrome coronavirus 2 | Ethnicity | Hydroxychloroquine | Data collection | Breast | Prostate | Smoking | Apoptosis | Index Medicus | Abridged Index Medicus
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7. Full Text Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial
by Sternberg, Cora N, Dr and Castellano, Daniel, MD and Daugaard, Gedske, Prof and Géczi, Lajos, MD and Hotte, Sebastien J, MD and Mainwaring, Paul N, MD and Saad, Fred, Prof and Souza, Ciro, MD and Tay, Miah H, MD and Garrido, José M Tello, MD and Galli, Luca, MD and Londhe, Anil, PhD and De Porre, Peter, MD and Goon, Betty, BS and Lee, Emma, PhD and McGowan, Tracy, MD and Naini, Vahid, PharmD and Todd, Mary B, DO and Molina, Arturo, MD and George, Daniel J, MD and for the Abiraterone Global EAP Investigators and Abiraterone Global EAP Investigat and Abiraterone Global EAP Investigators
The lancet oncology, ISSN 1470-2045, 2014, Volume 15, Issue 11, pp. 1263 - 1268
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Prednisolone - administration & dosage | Prognosis | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Neoplasm Recurrence, Local - mortality | Prostatic Neoplasms, Castration-Resistant - pathology | Dose-Response Relationship, Drug | Neoplasm Recurrence, Local - pathology | Neoplasm Invasiveness - pathology | Aged, 80 and over | Adult | Drug Therapy, Combination | Drug Administration Schedule | Administration, Oral | Kaplan-Meier Estimate | Androstenes | Treatment Outcome | Prostatic Neoplasms, Castration-Resistant - drug therapy | Disease Progression | Prostate-Specific Antigen - blood | Disease-Free Survival | Survival Analysis | Aged | Androstenols - administration & dosage | Prostatic Neoplasms, Castration-Resistant - mortality | Androgen Antagonists - administration & dosage | Neoplasm Staging | Care and treatment | Chemotherapy | Corticosteroids | Hospitals | Analysis | Prednisone | Metastasis | Prostate cancer | Cancer | Index Medicus
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