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index medicus (17) 17
immunology (14) 14
autoimmunity (13) 13
humans (12) 12
wiskott-aldrich syndrome (11) 11
abridged index medicus (10) 10
gene therapy (9) 9
wiskott-aldrich syndrome protein - genetics (9) 9
animals (8) 8
male (8) 8
wiskott-aldrich syndrome - immunology (8) 8
allergy (7) 7
bone marrow (7) 7
immunodeficiency (7) 7
mice (7) 7
transplantation (7) 7
b-lymphocytes - immunology (6) 6
patients (6) 6
wiskott-aldrich syndrome - genetics (6) 6
wiskott-aldrich syndrome - therapy (6) 6
allergy and immunology (5) 5
analysis (5) 5
care and treatment (5) 5
child (5) 5
genetic therapy (5) 5
genetic vectors (5) 5
health aspects (5) 5
hematopoietic stem cell transplantation (5) 5
hematopoietic stem cells (5) 5
lentivirus - genetics (5) 5
lymphocytes (5) 5
primary immunodeficiency (5) 5
signal transduction (5) 5
wiskott-aldrich syndrome - pathology (5) 5
wiskott-aldrich syndrome protein - deficiency (5) 5
wiskott-aldrich syndrome protein - metabolism (5) 5
child, preschool (4) 4
cloning (4) 4
disease models, animal (4) 4
expression (4) 4
gene expression (4) 4
immune system (4) 4
medicine, research & experimental (4) 4
mice, inbred c57bl (4) 4
mice, knockout (4) 4
proteins (4) 4
regulatory t-cells (4) 4
stem cells (4) 4
syndrome protein (4) 4
t-cells (4) 4
activation (3) 3
adult (3) 3
autoantibodies (3) 3
b cells (3) 3
b-cells (3) 3
base sequence (3) 3
bone marrow - pathology (3) 3
bone-marrow (3) 3
defects (3) 3
dendritic cells (3) 3
dendritic cells - immunology (3) 3
dendritic cells - metabolism (3) 3
efficacy (3) 3
female (3) 3
flow cytometry (3) 3
gene-therapy (3) 3
genes (3) 3
genetic aspects (3) 3
genetic therapy - methods (3) 3
homeostasis (3) 3
immune reconstitution (3) 3
immunoglobulins (3) 3
in-vivo (3) 3
infant (3) 3
laboratories (3) 3
mutation (3) 3
rna, messenger - metabolism (3) 3
syndrome protein-deficiency (3) 3
thrombocytopenia (3) 3
transduction, genetic (3) 3
transplants & implants (3) 3
wasp (3) 3
wiskott–aldrich syndrome (3) 3
x-linked thrombocytopenia (3) 3
actin polymerization (2) 2
actins - antagonists & inhibitors (2) 2
actins - metabolism (2) 2
activated platelets (2) 2
adolescent (2) 2
age (2) 2
amino acid sequence (2) 2
animal models (2) 2
antibodies (2) 2
antigens (2) 2
b-cell activating factor (2) 2
b-cell activating factor - genetics (2) 2
baff, b cell–activating factor (2) 2
blood platelets (2) 2
bone marrow - immunology (2) 2
bone marrow transplantation (2) 2
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Science (American Association for the Advancement of Science), ISSN 0036-8075, 8/2013, Volume 341, Issue 6148, pp. 865 - 865
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 692 - 702.e2
Background Wiskott-Aldrich syndrome (WAS) is a severe X-linked immunodeficiency characterized by microthrombocytopenia, eczema, recurrent infections, and... 
Allergy and Immunology | Wiskott-Aldrich syndrome | primary immunodeficiency | B cell | gene therapy | lentiviral vector | RHEUMATOID-ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | COMPLEMENT | ADHERENCE TEST | ACTIN POLYMERIZATION | SYNDROME PROTEIN | IMMUNOLOGY | TRANSPLANTATION | PRIMARY IMMUNODEFICIENCY DISEASES | ALLERGY | ACTIVATING FACTOR | LYMPHOCYTES | Wiskott-Aldrich Syndrome Protein - genetics | Bone Marrow - immunology | Humans | Recombinant Fusion Proteins - therapeutic use | Child, Preschool | Infant | Male | Transplantation, Autologous | Gene Expression Profiling | Autoantibodies - biosynthesis | Wiskott-Aldrich Syndrome - genetics | Wiskott-Aldrich Syndrome - therapy | Hematopoietic Stem Cells - immunology | Bone Marrow - metabolism | B-Lymphocyte Subsets - immunology | Lentivirus - genetics | Wiskott-Aldrich Syndrome - pathology | Child | Immunoglobulins - biosynthesis | Gene Expression | Wiskott-Aldrich Syndrome - immunology | Transduction, Genetic | B-Lymphocyte Subsets - pathology | Hematopoietic Stem Cell Transplantation | Immunophenotyping | Hematopoietic Stem Cells - metabolism | B-Cell Activating Factor - metabolism | B-Lymphocyte Subsets - metabolism | Wiskott-Aldrich Syndrome Protein - immunology | B-Cell Activating Factor - genetics | Bone Marrow - pathology | Transplantation Conditioning | Genetic Vectors | Genetic Therapy - methods | Autoimmunity | Care and treatment | Genetic vectors | Genes | Immunodeficiency | Genetic research | Lymphomas | Transplantation | Gene therapy | Health aspects | Hematopoietic stem cells | Bone marrow | Immunoglobulins | Patients | Immune Deficiencies, Infection, and Systemic Immune Disorders | WASp, Wiskott-Aldrich syndrome protein | WAS, Wiskott-Aldrich syndrome | GT, Gene therapy | PB, Peripheral blood | IVIg, Intravenous immunoglobulin | VCN, Vector copy number | HSC, Hematopoietic stem cell | HD, Healthy donor | BAFF, B cell–activating factor | BM, Bone marrow | SDF-1α, Stromal cell–derived factor 1α
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 3, pp. 799 - 806.e10
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 09/2019, Volume 144, Issue 3, pp. 825 - 838
Thrombocytopenia is a serious issue for all patients with classical Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT) because it causes severe... 
Wiskott-Aldrich syndrome | X-linked thrombocytopenia | gene therapy | platelets | CLEARANCE | CD40 LIGAND | CELL TRANSPLANTATION | SYNDROME PROTEIN | NEUTROPHILS | SPLENECTOMY | IMMUNOLOGY | ACTIVATED PLATELETS | ALLERGY | MUTATIONS | EXPRESSION | Genetic Therapy | Microscopy, Electron, Transmission | Humans | Child, Preschool | Hematopoietic Stem Cell Transplantation | Infant | Male | Blood Platelets - physiology | Wiskott-Aldrich Syndrome - therapy | Phenotype | Platelet Count | Platelet Activation | Blood Platelets - ultrastructure | Adolescent | Wiskott-Aldrich Syndrome Protein - metabolism | Adult | Female | Lentivirus - genetics | Wiskott-Aldrich Syndrome - blood | Child | Genetic research | Care and treatment | Genetic aspects | Gene therapy | Analysis | Flow cytometry | Pediatrics | Transplants & implants | Clinical trials | Agglomeration | Coexistence | Bleeding | Defects | Proteins | Genotype & phenotype | Signal transduction | Protein composition | Restoration | Blood platelets | Ultrastructure | Thrombocytopenia | Phenotypes | Immune reconstitution | Electron microscopy | Patients | Microscopy | Protein expression | Software | Mutation | Platelets | FERMT3, Fermitin family homolog 3 | TEM, Transmission electron microscopy | WAS, Wiskott-Aldrich syndrome | HMGB1, High-mobility group box 1 | δ-g, Electron-dense granule | GPX1, Glutathione peroxidase 1 | FU, Follow-up | sCD62P, Soluble P-selectin | sCD40L, Soluble CD40 ligand | BAFF, B cell–activating factor | CD62P, P-selectin | HSCT, Hematopoietic stem cell transplantation | WASp, Wiskott-Aldrich syndrome protein | MFI, Mean fluorescence intensity | LV, Lentivirus | CT, Closure time | GT, Gene therapy | OCS, Open canalicular system | PRP, Platelet-rich plasma | vWF, von Willebrand factor | STAT3, Signal transducer and activator of transcription 3 | HD, Healthy donor | ADP, Adenosine diphosphate | ROS, Reactive oxygen species | XLT, X-linked thrombocytopenia
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 127, Issue 6, pp. 1376 - 1384.e5
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2012, Volume 3, p. 209
Wiskott-Aldrich Syndrome (WAS) is a severe X-linked Primary Immunodeficiency that affects 1-10 out of 1 million male individuals. WAS is caused by mutations in... 
Autoimmunity | T lymphocytes | Wiskott-Aldrich syndrome | B lymphocytes | Primary immunodeficiency | primary immunodeficiency | IMMUNOLOGY | autoimmunity | Wiskott-Aldrich Syndrome
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2015, Volume 125, Issue 10, pp. 3941 - 3951
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 2, pp. 439 - 448.e8
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 09/2018, Volume 142, Issue 3, pp. 928 - 941.e8
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2016, Volume 213, Issue 3, pp. 355 - 375
Journal Article