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Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1559 - 1559
Abstract Acute myeloid leukemia (AML) develops by the acquisition of genomic alterations which initiate different pathways leading to full-blown malignancy.... 
Journal Article
Leukemia, ISSN 0887-6924, 4/2011, Volume 25, Issue 4, pp. 655 - 662
Cytokine signaling pathways are frequent targets of oncogenic mutations in acute myeloid leukemia, promoting proliferation and survival. We have previously... 
MPL | PlagL2 | acute myeloid leukemia | Cbfb-MYH11 | gene regulation | transcription factors
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2008, Volume 13, Issue 4, p. 289
Leukemia-initiating cells can originate from hematopoietic progenitor cells that have acquired self-renewal capacity upon transformation with leukemic fusion... 
Journal Article
Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6223, pp. 779 - 784
Acute myeloid leukemia (AML) is the most common form of adult leukemia. The transcription factor fusion CBF beta-SMMHC (core binding factor beta and the... 
RELAPSE SAMPLES | CBFB-MYH11 | FUSION | GENE | RAS | MULTIDISCIPLINARY SCIENCES | LEUKEMOGENESIS | ACUTE MYELOID-LEUKEMIA | PROTEINS | BINDING | RUNX1 | Drugs | Binding | Deregulation | Mice | Aberration | Leukemias | Delay | Cancer
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2008, Volume 13, Issue 4, pp. 289 - 291
Leukemia-initiating cells can originate from hematopoietic progenitor cells that have acquired self-renewal capacity upon transformation with leukemic fusion... 
STEM-CELLS | ABSENCE | PROGENITOR | LEUKEMIAS | MUTATIONS | ONCOLOGY
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 390 - 390
Abstract The leukemia fusion protein CBFβ-SMMHC, associated with acute myeloid leukemia (AML) with chromosome inversion inv(16)(p13q22), is a driver mutation... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 46 - 46
The core binding factor (CBF) is a transcription factor that regulates key modulators of growth, survival and differentiation pathways. The CBF consists of a... 
Journal Article
Blood, ISSN 0006-4971, 04/2009, Volume 113, Issue 14, pp. 3323 - 3332
Journal Article
BLOOD, ISSN 0006-4971, 04/2009, Volume 113, Issue 14, pp. 3323 - 3332
The core-binding factor (CBF) is a master regulator of developmental and differentiation programs, and CBF alterations are frequently associated with acute... 
YES-ASSOCIATED PROTEIN | AML1 GENE | DNA-BINDING | STEM-CELLS | ACUTE LYMPHOBLASTIC-LEUKEMIA | MULTIPLE CHROMOSOMAL TRANSLOCATIONS | T-CELL DEVELOPMENT | INSERTION LOCUS | HEMATOLOGY | INCREASED DOSAGE | BINDING-FACTOR | Myeloid Neoplasia
Journal Article
Science, ISSN 0036-8075, 02/2015, Volume 347, Issue 6223, pp. 779 - 784
Acute myeloid leukemia (AML) is the most common form of adult leukemia. The transcription factor fusion CBF[beta]-SMMHC (core binding factor [beta] and the... 
Transcription factors | Gene expression | Health aspects | Identification and classification | Studies | Proteins | Molecules | Chromosomes | Rodents | Leukemia
Journal Article
Journal of Virology, ISSN 0022-538X, 11/2006, Volume 80, Issue 22, pp. 11409 - 11415
Mice harboring three mouse mammary tumor virus (MMTV) variants develop pregnancy-dependent (PD) tumors that progress to pregnancy-independent (PI) behavior... 
Journal Article
EBioMedicine, ISSN 2352-3964, 06/2016, Volume 8, Issue C, pp. 117 - 131
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 286 - 286
Abstract Abstract 286 Emerging literature suggests that inability to cure cancers with current therapies may be attributed to a population of so-called cancer... 
Journal Article
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