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American Journal of Medical Genetics Part A, ISSN 1552-4825, 02/2017, Volume 173, Issue 2, pp. 537 - 540
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 07/2011, Volume 9, Issue 1, pp. 103 - 103
Journal Article
BioFactors, ISSN 0951-6433, 01/2016, Volume 42, Issue 1, pp. 60 - 79
Insulin‐like growth factor 1 (IGF‐1) induces multiple cytoprotective effects on every tissue, including the brain. Since the mechanisms by which IGF‐1 produces... 
IGF‐1 | magnetic resonance imaging | autophagy | learning and memory | neuroprotection | neurodegeneration | oxidative damage | apoptosis | heat shock proteins | gene expression | Learning and memory | Neuroprotection | Magnetic resonance imaging | Neurodegeneration | Oxidative damage | Heat shock proteins | IGF-1 | Gene expression | Autophagy | Apoptosis | STEM-CELLS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER | HIPPOCAMPUS | CIRRHOSIS | MITOCHONDRIAL PROTECTION | ENDOCRINOLOGY & METABOLISM | MICE | DYSFUNCTION | GROWTH-FACTOR-I | AGING RATS | Inflammation - pathology | Apoptosis - drug effects | Learning - drug effects | Antioxidants - metabolism | Humans | Heat-Shock Proteins - biosynthesis | Insulin-Like Growth Factor I - genetics | Brain Injuries - metabolism | Brain - metabolism | Inflammation - metabolism | Lipid Peroxidation - drug effects | Insulin-Like Growth Factor I - therapeutic use | Edema - therapy | Insulin-Like Growth Factor I - deficiency | Mitochondria - metabolism | Brain Injuries - therapy | Mitochondria - drug effects | Neuroprotection - genetics | Gene Expression Regulation - drug effects | Edema - metabolism | Inflammation - therapy | Animals | Brain - pathology | Mice | Oxidative Stress - drug effects | Brain Injuries - pathology | Edema - pathology | Antioxidants | Enzymes | Dropsy | Edema | Brain damage
Journal Article
Liver International, ISSN 1478-3223, 01/2009, Volume 29, Issue 1, pp. 37 - 46
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0181760
Circulating levels of IGF-1 may decrease under several circumstances like ageing, metabolic syndrome, and advanced cirrhosis. This reduction is associated with... 
G(BETA-GAMMA) SUBUNITS | MYOCARDIAL-INFARCTION | HSP47 | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | RECEPTOR | MICE | ISCHEMIA-REPERFUSION | INSULIN SENSITIVITY | GROWTH-FACTOR-I | DIASTOLIC DYSFUNCTION | Angiotensin II - pharmacology | Extracellular Matrix - drug effects | Body Weight - drug effects | Extracellular Matrix - metabolism | Insulin-Like Growth Factor I - deficiency | Myocardial Contraction - drug effects | Mice, Transgenic | Myocardium - pathology | Vasoconstriction - drug effects | Gene Expression Regulation - drug effects | Myocardial Contraction - genetics | Organ Size - drug effects | Animals | Perfusion | Myocardium - metabolism | Hemodynamics - drug effects | Vasodilation - drug effects | Real-Time Polymerase Chain Reaction | Bradykinin - pharmacology | Insulin-Like Growth Factor I - metabolism | Type 2 diabetes | Dyslipidemias | Angiotensin | Insulin resistance | Development and progression | Research | Gene expression | Cardiovascular diseases | Risk factors | Heart | Calcium | Peptides | Insulin-like growth factor I | Dyslipidemia | Insulin-like growth factors | Kinases | Proteins | Calcium signalling | Reduction | Reperfusion | Ischemia | Vasoactive agents | Rodents | Extracellular matrix | Angiotensin II | Heart diseases | Diabetes mellitus | Health risks | Contractility | Coronary circulation | Histology | Insulin | Muscle contraction | Coronary artery disease | Cirrhosis | DNA microarrays | Fibrosis | Metabolic disorders | Circulation | Calcium (extracellular) | Structure-function relationships
Journal Article
Urology, ISSN 0090-4295, 2015, Volume 86, Issue 6, pp. 1241.e1 - 1241.e9
Objective To determine whether insulin-like growth factor (IGF-1) deficiency can cause testicular damage and to examine changes of the testicular morphology... 
Urology | SYSTEM | LIVER-CIRRHOSIS | HORMONE | LEYDIG-CELLS | HUMAN SKIN | ALCOHOL | HUMAN TESTIS | ATROPHY | UROLOGY & NEPHROLOGY | EXPRESSION | GROWTH-FACTOR-I | Insulin-Like Growth Factor I - pharmacology | Gene Expression - drug effects | Gene Expression - genetics | beta Catenin - analysis | Zonula Occludens-1 Protein - analysis | Male | Insulin-Like Growth Factor I - genetics | Vascular Endothelial Growth Factor A - genetics | Tight Junctions - chemistry | Blood-Testis Barrier - chemistry | Cytochrome P-450 CYP3A - genetics | Fertilins | Disease Models, Animal | Receptors, FSH - analysis | Insulin-Like Growth Factor Binding Proteins - genetics | CD18 Antigens - genetics | Extracellular Matrix Proteins - genetics | Insulin-Like Growth Factor I - deficiency | Metalloproteases - genetics | Organ Size | Cadherins - analysis | Genotype | Signal Transduction - genetics | Receptor, IGF Type 1 - genetics | Receptors, Somatotropin - genetics | Testis - chemistry | Transforming Growth Factor alpha - genetics | Membrane Glycoproteins - genetics | Receptors, Somatotropin - analysis | Tissue Inhibitor of Metalloproteinase-1 - genetics | Animals | Testis - pathology | Transforming Growth Factor beta - genetics | Signal Transduction - drug effects | Connective Tissue Growth Factor - genetics | Inhibins - genetics | Mice | Testis - physiopathology | ADAM Proteins - genetics | Proteoglycans - genetics | Gene expression | Physiological aspects | Somatotropin | Analysis | Genes
Journal Article
Clinical Case Reports, ISSN 2050-0904, 02/2018, Volume 6, Issue 2, pp. 426 - 431
Key Clinical Message We report a case of short stature irresponsive to growth hormone (GH) replacement therapy. Low GH response to provocative tests and... 
IGF‐1 | GH insensitivity | GH resistance | Laron Syndrome | GH/IGF‐1 axis | IGF-1 | GH/IGF-1 axis
Journal Article