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by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature (London), ISSN 1476-4687, 2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article
by Vos, Theo and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulkader, Rizwan Suliankatchi and Abdulle, Abdishakur M and Abera, Semaw Ferede and Abu-Raddad, Laith J and Adetokunboh, Olatunji and Afshin, Ashkan and Agarwal, Sanjay Kumar and Aggarwal, Rakesh and Agrawal, Anurag and Agrawal, Sutapa and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Amani Nidhal and Aichour, Ibtihel and Aiyar, Sneha and Akseer, Nadia and Al Lami, Faris Hasan and Alahdab, Fares and Al-Aly, Ziyad and Alam, Khurshid and Alam, Tahiya and Alasfoor, Deena and Ali, Raghib and Alizadeh-Navaei, Reza and Alla, François and Allebeck, Peter and Allen, Christine and Al-Maskari, Fatma and Alsowaidi, Shirina and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Antonio, Carl Abelardo T and Artaman, Al and Assadi, Reza and Atnafu, Niguse Tadele and Atre, Sachin R and Avila-Burgos, Leticia and Bacha, Umar and Banerjee, Amitava and Barac, Aleksandra and Barker-Collo, Suzanne L and Bärnighausen, Till and Barrero, Lope H and Basu, Sanjay and Battista, Bob and Battle, Katherine E and Baune, Bernhard T and Bazargan-Hejazi, Shahrzad and Beardsley, Justin and Bedi, Neeraj and Beghi, Ettore and Bell, Michelle L and Bensenor, Isabela M and Benson, Jennifer and Berhane, Adugnaw and Berhe, Derbew Fikadu and Bernabé, Eduardo and Betsu, Balem Demtsu and Beuran, Mircea and Beyene, Addisu Shunu and Bhala, Neeraj and Bhansali, Anil and Bhatt, Samir and Bhutta, Zulfiqar A and Biadgilign, Sibhatu and Bikbov, Boris and Bisanzio, Donal and Bizuayehu, Habtamu Mellie and Boneya, Dube Jara and Boufous, Soufiane and Bourne, Rupert R A and Brazinova, Alexandra and Bumgarner, Blair R and Cahuana-Hurtado, Lucero and Cameron, Ewan and Car, Mate and Carabin, Hélène and Cárdenas, Rosario and Carrero, Juan Jesus and Carvalho, Felix and Casey, Daniel C and Caso, Valeria and Castle, Chris D and Chang, Hsing-Yi and Charlson, Fiona J and Chen, Honglei and Chisumpa, Vesper Hichilombwe and Chitheer, Abdulaal A and Christopher, Devasahayam Jesudas and Ciobanu, Liliana G and Cirillo, Massimo and Colombara, Danny and Cortesi, Paolo Angelo and Criqui, Michael H and ... and GBD 2016 Disease and Injury Incidence and Prevalence Collaborators and GBD 2016 Dis Injury Incidence Prev and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri and Göteborgs universitet and Gothenburg University and Institute of Medicine, School of Public Health and Community Medicine and Sahlgrenska Academy and Sahlgrenska akademin and Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics
The Lancet (British edition), ISSN 0140-6736, 09/2017, Volume 390, Issue 10100, pp. 1211 - 1259
As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the... 
MORTALITY | DEPRESSION | CHRONIC PAIN | CLIMATE-CHANGE | DISORDERS | FUTURE | PERSONAL HEALTH-CARE | TRENDS | MEDICINE, GENERAL & INTERNAL | Medicine, Experimental | Medical research | Mental disorders | Disease | Personal health | Mortality | Mental health | Disease control | Risk factors | Studies | Disability | Aging | Age | Public health | Injury analysis | Injuries | Chronic illnesses | Guillain-Barre syndrome | Low back pain | Gout | Disorders | Mental depression | Tropical diseases | Incidence | Ratios | Fertility | Anxiety | Alzheimer's disease | Life expectancy | Population growth | Nutrient deficiency | Neurodegenerative diseases | Violence | Anemia | Regression analysis | Firearms | Self destructive behavior | Hearing loss | Diseases | Charities | Substance use | Hospitals | Tuberculosis | Adults | Cardiovascular diseases | Bayesian analysis | Headache | Iron | Sexual assault | Demographics | Pain | Remission | Children | Heart diseases | Complications | Aggression | Migraine | Diabetes mellitus | Health risks | Estimates | Life span | Community medicine, Social medicine: 801 | Samfunnsmedisin, sosialmedisin: 801 | Epidemiology medical and dental statistics: 803 | Epidemiologi medisinsk og odontologisk statistikk: 803 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Global Health Metrics | disorders | chronic pain | future | Hälsovetenskaper | personal health-care | mortality | depression | General & Internal Medicine | climate-change | trends | Health Sciences
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2014, Volume 371, Issue 3, pp. 234 - 247
Journal Article
by Zeggini, E and Weedon, M. N and Lindgren, C. M and Frayling, T. M and Elliott, K. S and Lango, H and Timpson, N. J and Perry, J. R. B and Rayner, N. W and Freathy, R. M and Barrett, J. C and Shields, B and Morris, A. P and Ellard, S and Groves, C. J and Harries, L. W and Marchini, J. L and Owen, K. R and Knight, B and Cardon, L. R and Walker, M and Hitman, G. A and Morris, A. D and Doney, A. S. F and Burton, P. R and Clayton, D. G and Craddock, N and Deloukas, P and Duncanson, A and Kwiatkowski, D. P and Ouwehand, W. H and Samani, N. J and Todd, J. A and Donnelly, P and Davison, D and Easton, D and Evans, D and Leung, H.-T and Spencer, C. C. A and Tobin, M. D and Attwood, A. P and Boorman, J. P and Cant, B and Everson, U and Hussey, J. M and Jolley, J. D and Knight, A. S and Koch, K and Meech, E and Nutland, S and Prowse, C. V and Stevens, H. E and Taylor, N. C and Walters, G. R and Walker, N. M and Watkins, N. A and Winzer, T and Jones, R. W and McArdle, W. L and Ring, S. M and Strachan, D. P and Pembrey, M and Breen, G and St. Clair, D and Caesar, S and Gordon-Smith, K and Jones, L and Fraser, C and Green, E. K and Grozeva, D and Hamshere, M. L and Holmans, P. A and Jones, I. R and Kirov, G and Moskvina, V and Nikolov, I and O'Donovan, M. C and Owen, M. J and Collier, D. A and Elkin, A and Farmer, A and Williamson, R and McGuffin, P and Young, A. H and Ferrier, I. N and Ball, S. G and Balmforth, A. J and Barrett, J. H and Bishop, D. T and Iles, M. M and Maqbool, A and Yuldasheva, N and Hall, A. S and Braund, P. S and Dixon, R. J and Mangino, M and Stevens, S and Thompson, J. R and Bredin, F and Tremelling, M and ... and The Wellcome Trust Case Control Consortium (WTCCC) and WTCCC and Wellcome Trust Case Control Consortium (WTCCC)
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2007, Volume 316, Issue 5829, pp. 1336 - 1341
Journal Article
by Abajobir, Amanuel Alemu and Abate, Kalkidan Hassen and Abbafati, Cristiana and Abbas, Kaja M and Abd-Allah, Foad and Abdulle, Abdishakur M and Abera, Semaw Ferede and Aboyans, Victor and Abu-Raddad, Laith J and Ackerman, Ilana N and Adedeji, Isaac A and Adetokunboh, Olatunji and Afshin, Ashkan and Aggarwal, Rakesh and Agrawal, Sutapa and Agrawal, Anurag and Ahmed, Muktar Beshir and Aichour, Miloud Taki Eddine and Al-Aly, Ziyad and Alam, Khurshid and Alam, Noore and Alasfoor, Deena and Alene, Kefyalew Addis and Ali, Raghib and Alizadeh-Navaei, Reza and Alkaabi, Juma M and Alkerwi, Ala'a and Alla, François and Allebeck, Peter and Al-Maskari, Fatma and Al-Raddadi, Rajaa and Alsharif, Ubai and Alsowaidi, Shirina and Altirkawi, Khalid A and Amare, Azmeraw T and Amini, Erfan and Ammar, Walid and Amoako, Yaw Ampem and Ansha, Mustafa Geleto and Antonio, Carl Abelardo T and Ärnlöv, Johan and Arora, Megha and Asgedom, Solomon W and Atey, Tesfay Mehari and Avila-Burgos, Leticia and Awasthi, Ashish and Awasthi, Shally and Azarpazhooh, Mahmoud Reza and Azzopardi, Peter and Babalola, Tesleem Kayode and Balakrishnan, Kalpana and Bannick, Marlena S and Barac, Aleksandra and Barker-Collo, Suzanne L and Barquera, Simon and Basu, Sanjay and Battista, Robert and Battle, Katherine E and Baune, Bernhard T and Beardsley, Justin and Béjot, Yannick and Bekele, Bayu Begashaw and Bensenor, Isabela M and Benson, Jennifer and Berhane, Adugnaw and Berhe, Derbew Fikadu and Beuran, Mircea and Beyene, Addisu Shunu and Bhatt, Samir and Bhutta, Zulfiqar A and Biadgilign, Sibhatu and Bicer, Burcu Kucuk and Bikbov, Boris and Bisanzio, Donal and Blyth, Fiona M and Bou-Orm, Ibrahim R and Bourne, Rupert R A and Brainin, Michael and Brayne, Carol and Breitborde, Nicholas J K and Briant, Paul S and Britton, Gabrielle and Bulto, Lemma Negesa Bulto and Cahuana-Hurtado, Lucero and Cameron, Ewan and Campos-Nonato, Ismael Ricardo and Carpenter, David O and Carrero, Juan Jesus and Carter, Austin and Casey, Daniel and Castañeda-Orjuela, Carlos A and Catalá-López, Ferrán and Chang, Jung-Chen and Charlson, Fiona J and Chaturvedi, Pankaj and Chen, Honglei and Chisumpa, Vesper Hichilombwe and Chowdhury, Rajiv and Ciobanu, Liliana G and Colombara, Danny and ... and GBD 2016 DALYs and HALE Collaborators and GBD 2016 DALYs HALE Collaborators and Sahlgrenska akademin and Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa, enheten för hälsometri and Institute of Medicine, Department of Public Health and Community Medicine, Health Metrics and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The Lancet (British edition), ISSN 0140-6736, 09/2017, Volume 390, Issue 10100, pp. 1260 - 1344
Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and... 
MORTALITY | AFRICA | AUSTRALIA | THERAPY | EPIDEMIOLOGIC TRANSITION | HIV | PLASMODIUM-FALCIPARUM | WEIGHTS | PREVALENCE | ASSOCIATION | TRANSITION | MEDICINE, GENERAL & INTERNAL | EPIDEMIOLOGY | Quality-Adjusted Life Years | Age Distribution | Global Burden of Disease - statistics & numerical data | Humans | Middle Aged | Male | Noncommunicable Diseases - mortality | Wounds and Injuries - mortality | Life Expectancy | Residence Characteristics - statistics & numerical data | Global Health - statistics & numerical data | Aged, 80 and over | Sex Distribution | Adult | Cause of Death - trends | Disabled Persons - statistics & numerical data | Female | Aged | Communicable Diseases - mortality | Medicine, Experimental | Medical research | Life expectancy | Health aspects | Epidemiology | Analysis | Health care | Life span | Disease | Mortality | Mental health | Population | Age | Risk factors | Injuries | Public health | Sociodemographics | Neonates | Compression | Resource allocation | Sex | Males | Demographics | Mathematical analysis | Fertility | Trends | Heart diseases | Family planning | Decision making | Health risks | Benchmarks | Risk analysis | Coronary artery disease | Morbidity | Diseases | Studies | Charities | Females | Helse- og sykehusadministrasjon / Health Services Administration | VDP | Midical sciences: 700 | Medisinske fag: 700 | Helsefag: 800 | Health sciences: 800 | Health service and health administration research: 806 | Helsetjeneste- og helseadministrasjonsforskning: 806 | Global Helse / Global Health | Helsepolitikk / Health policy | Global Health Metrics | plasmodium-falciparum | africa | therapy | Hälsovetenskaper | association | australia | weights | prevalence | hiv | mortality | epidemiologic transition | General & Internal Medicine | Health Sciences
Journal Article