Nature Methods, ISSN 1548-7091, 02/2017, Volume 14, Issue 3, pp. 279 - 282
The ability to selectively interfere with post-translationally modified proteins would have many biological and therapeutic applications. However,...
ANTIBODIES | BETA OLIGOMERS | CELLS | 2-HYBRID SYSTEM | IN-VITRO | HISTONE DEACETYLASES | BIOCHEMICAL RESEARCH METHODS | FRAGMENT | EXPRESSION | CANCER | Histones - immunology | Humans | Antibodies - immunology | HIV Integrase - immunology | Acetylation | Histones - metabolism | HIV Integrase - metabolism | Protein Processing, Post-Translational - immunology | Proteins | Viral antibodies | Post-translational modification | Analysis | Physiological aspects | Antibodies | Research | Cellular biology | Immunoglobulins
ANTIBODIES | BETA OLIGOMERS | CELLS | 2-HYBRID SYSTEM | IN-VITRO | HISTONE DEACETYLASES | BIOCHEMICAL RESEARCH METHODS | FRAGMENT | EXPRESSION | CANCER | Histones - immunology | Humans | Antibodies - immunology | HIV Integrase - immunology | Acetylation | Histones - metabolism | HIV Integrase - metabolism | Protein Processing, Post-Translational - immunology | Proteins | Viral antibodies | Post-translational modification | Analysis | Physiological aspects | Antibodies | Research | Cellular biology | Immunoglobulins
Journal Article
Glia, ISSN 0894-1491, 07/2018, Volume 66, Issue 7, pp. 1395 - 1416
Microglia are the sentinels of the brain but a clear understanding of the factors that modulate their activation in physiological and pathological conditions...
amyloid | macropinocytosis | neuroimmune communication | nerve growth factor | neuroinflammation | neuroprotection | neurotrophin | microglia | FOREBRAIN CHOLINERGIC NEURONS | ALZHEIMERS-DISEASE | SYNAPTIC PLASTICITY | NEUROSCIENCES | NERVE GROWTH-FACTOR | AMYLOID-BETA | IN-VIVO | MOUSE MODEL | BASAL FOREBRAIN | FACTOR GENE-THERAPY | TRANSGENIC MICE | Physiological aspects | Nerve growth factor | Genetic aspects | Neurons | Analysis | Potentiation | Neuroprotection | Brain | Physiological effects | Phenotypes | Brain slice preparation | Long-term potentiation | Activation | Inflammation | Microglia | Degradation | Dendritic spines | Receptors | Nerve growth factor receptors | Microglial cells | TrkA protein | TrkA receptors | Glutamatergic transmission | Neurotransmission | Phagocytosis
amyloid | macropinocytosis | neuroimmune communication | nerve growth factor | neuroinflammation | neuroprotection | neurotrophin | microglia | FOREBRAIN CHOLINERGIC NEURONS | ALZHEIMERS-DISEASE | SYNAPTIC PLASTICITY | NEUROSCIENCES | NERVE GROWTH-FACTOR | AMYLOID-BETA | IN-VIVO | MOUSE MODEL | BASAL FOREBRAIN | FACTOR GENE-THERAPY | TRANSGENIC MICE | Physiological aspects | Nerve growth factor | Genetic aspects | Neurons | Analysis | Potentiation | Neuroprotection | Brain | Physiological effects | Phenotypes | Brain slice preparation | Long-term potentiation | Activation | Inflammation | Microglia | Degradation | Dendritic spines | Receptors | Nerve growth factor receptors | Microglial cells | TrkA protein | TrkA receptors | Glutamatergic transmission | Neurotransmission | Phagocytosis
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e61496
The primary motor cortex (M1) supports motor skill learning, yet little is known about the genes that contribute to motor cortical plasticity. Such knowledge...
SYNAPTOGENESIS | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | REPRESENTATION | REORGANIZATION | DIFFERENTIATION | PROTEINS | TRANSCRIPTIONAL REPRESSOR | MORPHOLOGY | PLASTICITY | MOLECULES | Motor Cortex - physiology | Reproducibility of Results | Molecular Sequence Annotation | Gene Expression Regulation | Fibroblast Growth Factors - genetics | Rats | Male | Gene Expression Profiling | Synapses - genetics | Learning - physiology | Animals | Time Factors | Motor Skills | Cluster Analysis | Motor cortex | Physiological aspects | Genetic aspects | Models | Research | Gene expression | Motor learning | Fibroblast growth factor | Neurosciences | Synaptogenesis | Circuits | Genes | Intracellular signalling | Genomes | Cortex (motor) | Motor task performance | Training | Ischemia | Skills | Rodents | Plasticity (cortical) | Plasticity | Reinforcement | Fibroblasts | Behavior | Growth factors | Stroke | Motor ability | Medical treatment | Motor skill | Clustering | Brain research | Plasticity (synaptic) | Motor skill learning | Morphology | Cytoskeleton | Laboratory animals | Animal cognition
SYNAPTOGENESIS | PERFORMANCE | MULTIDISCIPLINARY SCIENCES | REPRESENTATION | REORGANIZATION | DIFFERENTIATION | PROTEINS | TRANSCRIPTIONAL REPRESSOR | MORPHOLOGY | PLASTICITY | MOLECULES | Motor Cortex - physiology | Reproducibility of Results | Molecular Sequence Annotation | Gene Expression Regulation | Fibroblast Growth Factors - genetics | Rats | Male | Gene Expression Profiling | Synapses - genetics | Learning - physiology | Animals | Time Factors | Motor Skills | Cluster Analysis | Motor cortex | Physiological aspects | Genetic aspects | Models | Research | Gene expression | Motor learning | Fibroblast growth factor | Neurosciences | Synaptogenesis | Circuits | Genes | Intracellular signalling | Genomes | Cortex (motor) | Motor task performance | Training | Ischemia | Skills | Rodents | Plasticity (cortical) | Plasticity | Reinforcement | Fibroblasts | Behavior | Growth factors | Stroke | Motor ability | Medical treatment | Motor skill | Clustering | Brain research | Plasticity (synaptic) | Motor skill learning | Morphology | Cytoskeleton | Laboratory animals | Animal cognition
Journal Article
Frontiers in Molecular Neuroscience, ISSN 1662-5099, 02/2017, Volume 10, p. 20
ProNGF, the precursor of mature Nerve Growth Factor (NGF), is the most abundant NGF form in the brain and increases markedly in the cortex in Alzheimer's...
Dentate gyrus | Expression profile | Interneurons | Transgenic mice | Extracellular matrix | E/I imbalance | Parvalbumin | ProNGF | ALZHEIMERS-DISEASE | NEUROTROPHIC FACTOR | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | PREFRONTAL CORTEX | NERVE GROWTH-FACTOR | INDUCED NEURONAL DYSFUNCTION | dentate gyrus | transgenic mice | RNA SPLICE VARIANTS | VISUAL-CORTEX | parvalbumin | IN-VIVO | proNGF | EXTRACELLULAR-MATRIX | extracellular matrix | expression profile | interneurons | Genetically modified mice | Nerve growth factor | Research | Health aspects | Alternative splicing | Amygdala | Transcription | Gene regulation | Brain slice preparation | Epilepsy | Cognitive ability | Homeostasis | Experiments | Genotype & phenotype | Neurodegeneration | Synaptic transmission | Transgenic animals | Down-regulation | Furin | Growth factors | Alzheimer's disease | Phenotypes | Firing pattern | Gene families | Gene expression | Cortex (entorhinal) | Brain-derived neurotrophic factor | Immunoreactivity | Laboratory animals | Alzheimers disease | Hippocampus
Dentate gyrus | Expression profile | Interneurons | Transgenic mice | Extracellular matrix | E/I imbalance | Parvalbumin | ProNGF | ALZHEIMERS-DISEASE | NEUROTROPHIC FACTOR | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | PREFRONTAL CORTEX | NERVE GROWTH-FACTOR | INDUCED NEURONAL DYSFUNCTION | dentate gyrus | transgenic mice | RNA SPLICE VARIANTS | VISUAL-CORTEX | parvalbumin | IN-VIVO | proNGF | EXTRACELLULAR-MATRIX | extracellular matrix | expression profile | interneurons | Genetically modified mice | Nerve growth factor | Research | Health aspects | Alternative splicing | Amygdala | Transcription | Gene regulation | Brain slice preparation | Epilepsy | Cognitive ability | Homeostasis | Experiments | Genotype & phenotype | Neurodegeneration | Synaptic transmission | Transgenic animals | Down-regulation | Furin | Growth factors | Alzheimer's disease | Phenotypes | Firing pattern | Gene families | Gene expression | Cortex (entorhinal) | Brain-derived neurotrophic factor | Immunoreactivity | Laboratory animals | Alzheimers disease | Hippocampus
Journal Article
BMC BIOINFORMATICS, ISSN 1471-2105, 04/2019, Volume 20, Issue Suppl 4, pp. 138 - 14
BackgroundDistributed approaches based on the MapReduce programming paradigm have started to be proposed in the Bioinformatics domain, due to the large amount...
Performance evaluation | k-mer counting | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | MAPREDUCE | Distributed computing | Apache Spark | Library collections | Statistical analysis | Big Data | Data processing | Statistics | Exploitation | Workload | Case studies | Datasets | Next-generation sequencing | Algorithms | Data management | Data sets | Linguistics | Collection | Software | Bioinformatics | Software engineering
Performance evaluation | k-mer counting | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | MAPREDUCE | Distributed computing | Apache Spark | Library collections | Statistical analysis | Big Data | Data processing | Statistics | Exploitation | Workload | Case studies | Datasets | Next-generation sequencing | Algorithms | Data management | Data sets | Linguistics | Collection | Software | Bioinformatics | Software engineering
Journal Article
BRITISH JOURNAL OF CANCER, ISSN 0007-0920, 10/2019, Volume 121, Issue 9, pp. 768 - 775
BACKGROUND: Current approaches aimed at inducing immunogenic cell death (ICD) to incite an immune response against cancer neoantigens are based on the use of...
CALRETICULIN EXPOSURE | GALACTOSIDE-BINDING PROTEIN | BETA-GBP | PI3K | ONCOLOGY | PATHWAY | ER STRESS | AUTOPHAGY | Coupling agents | Toxicity | p53 Protein | Xenotransplantation | Colorectal carcinoma | Colorectal cancer | Cytotoxicity | Activation | Lymphocytes T | Autophagy | Cell surface | Western blotting | Cell activation | Lymphocytes | Xenografts | Immune system | Immune response | Priming | Immunosurveillance | Electron microscopy | Polymerase chain reaction | Immunogenicity | Cell death | Immunofluorescence | Combinatorial analysis | Phagocytosis | Tumors | Apoptosis | Cancer | Cytofluorometry
CALRETICULIN EXPOSURE | GALACTOSIDE-BINDING PROTEIN | BETA-GBP | PI3K | ONCOLOGY | PATHWAY | ER STRESS | AUTOPHAGY | Coupling agents | Toxicity | p53 Protein | Xenotransplantation | Colorectal carcinoma | Colorectal cancer | Cytotoxicity | Activation | Lymphocytes T | Autophagy | Cell surface | Western blotting | Cell activation | Lymphocytes | Xenografts | Immune system | Immune response | Priming | Immunosurveillance | Electron microscopy | Polymerase chain reaction | Immunogenicity | Cell death | Immunofluorescence | Combinatorial analysis | Phagocytosis | Tumors | Apoptosis | Cancer | Cytofluorometry
Journal Article
PLOS NEGLECTED TROPICAL DISEASES, ISSN 1935-2735, 08/2014, Volume 8, Issue 8, p. e3057
Human cystic echinococcosis is a chronic, complex and neglected infection. Its clinical management has evolved over decades without adequate evaluation of...
DIAGNOSIS | CLASSIFICATION | HYDATID-DISEASE | ULTRASOUND | PARASITOLOGY | TROPICAL MEDICINE | Follow-Up Studies | Echinococcosis, Hepatic - diagnosis | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Echinococcosis, Hepatic - diagnostic imaging | Animals | Adolescent | Ultrasonography | Aged, 80 and over | Abdomen - diagnostic imaging | Adult | Female | Aged | Cysts - diagnosis | Serologic Tests | Care and treatment | Usage | Ultrasound imaging | Analysis | Causes of | Serology | Diagnosis | Biological markers | Echinococcosis | Cysts | Liver | Classification | Infections | Patients | Biological activity | Abdomen
DIAGNOSIS | CLASSIFICATION | HYDATID-DISEASE | ULTRASOUND | PARASITOLOGY | TROPICAL MEDICINE | Follow-Up Studies | Echinococcosis, Hepatic - diagnosis | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Echinococcosis, Hepatic - diagnostic imaging | Animals | Adolescent | Ultrasonography | Aged, 80 and over | Abdomen - diagnostic imaging | Adult | Female | Aged | Cysts - diagnosis | Serologic Tests | Care and treatment | Usage | Ultrasound imaging | Analysis | Causes of | Serology | Diagnosis | Biological markers | Echinococcosis | Cysts | Liver | Classification | Infections | Patients | Biological activity | Abdomen
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20839
The biological activities of NGF and of its precursor proNGF are quite distinct, due to different receptor binding profiles, but little is known about how...
PHEOCHROMOCYTOMA CELLS | NEURITE OUTGROWTH | PRIMARY RESPONSE GENES | ALZHEIMERS-DISEASE | BIOLOGY | FACTOR RECEPTORS | MOLECULAR-CLONING | DEATH | LOW-AFFINITY | CHOLESTEROL-BIOSYNTHESIS | NERVE GROWTH-FACTOR | Protein Precursors - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation | Rats | Gene Expression Profiling | Nerve Growth Factors - metabolism | RNA, Messenger - metabolism | PC12 Cells | Protein Precursors - metabolism | Animals | Microarray Analysis | Nerve Growth Factors - genetics | Proteins | Messenger RNA | Analysis | Genetic research | Nerve growth factor | Gene expression | Apoptosis | Transcription | Genes | Genomes | Biosynthesis | Kinases | Neurodegeneration | Rodents | Furin | Tumor necrosis factor-TNF | Bioinformatics | Growth factors | Recombinant | Neurons | Gene families | Cholesterol | Signaling | Brain research | DNA microarrays | Pheochromocytoma cells | Spinal cord injuries | Alzheimers disease
PHEOCHROMOCYTOMA CELLS | NEURITE OUTGROWTH | PRIMARY RESPONSE GENES | ALZHEIMERS-DISEASE | BIOLOGY | FACTOR RECEPTORS | MOLECULAR-CLONING | DEATH | LOW-AFFINITY | CHOLESTEROL-BIOSYNTHESIS | NERVE GROWTH-FACTOR | Protein Precursors - genetics | Humans | RNA, Messenger - genetics | Gene Expression Regulation | Rats | Gene Expression Profiling | Nerve Growth Factors - metabolism | RNA, Messenger - metabolism | PC12 Cells | Protein Precursors - metabolism | Animals | Microarray Analysis | Nerve Growth Factors - genetics | Proteins | Messenger RNA | Analysis | Genetic research | Nerve growth factor | Gene expression | Apoptosis | Transcription | Genes | Genomes | Biosynthesis | Kinases | Neurodegeneration | Rodents | Furin | Tumor necrosis factor-TNF | Bioinformatics | Growth factors | Recombinant | Neurons | Gene families | Cholesterol | Signaling | Brain research | DNA microarrays | Pheochromocytoma cells | Spinal cord injuries | Alzheimers disease
Journal Article
BMC Neuroscience, ISSN 1471-2202, 04/2014, Volume 15, Issue 1, pp. 48 - 48
Background: Growing evidence shows that, in vivo, the precursor of Nerve Growth Factor (NGF), proNGF, displays biological activities different from those of...
Neurotrophin | PC12 | Transcription | NGF/proNGF ratio | proNGF | Early genes | Gene expression | NGF | ALZHEIMERS-DISEASE | INJURY | DEATH | NEUROSCIENCES | NERVE GROWTH-FACTOR | TRANSCRIPTS | PRIMARY RESPONSE GENES | FACTOR PRECURSOR | SORTILIN | PROTEINS | Animals | Nerve Growth Factor - metabolism | Gene Expression Regulation, Neoplastic | Rats | Neoplasm Proteins - metabolism | PC12 Cells | Protein Precursors - metabolism | Genetic transcription | Proteins | Data analysis | Brain research | Neurodegeneration | Rodents | Data bases
Neurotrophin | PC12 | Transcription | NGF/proNGF ratio | proNGF | Early genes | Gene expression | NGF | ALZHEIMERS-DISEASE | INJURY | DEATH | NEUROSCIENCES | NERVE GROWTH-FACTOR | TRANSCRIPTS | PRIMARY RESPONSE GENES | FACTOR PRECURSOR | SORTILIN | PROTEINS | Animals | Nerve Growth Factor - metabolism | Gene Expression Regulation, Neoplastic | Rats | Neoplasm Proteins - metabolism | PC12 Cells | Protein Precursors - metabolism | Genetic transcription | Proteins | Data analysis | Brain research | Neurodegeneration | Rodents | Data bases
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 2014, Volume 8, Issue 8, p. e3057
Journal Article
BMC BIOINFORMATICS, ISSN 1471-2105, 04/2019, Volume 20
Background: Distributed approaches based on the MapReduce programming paradigm have started to be proposed in the Bioinformatics domain, due to the large...
Performance evaluation | k-mer counting | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | MAPREDUCE | Distributed computing | COMPUTATIONAL BIOLOGY | Apache Spark
Performance evaluation | k-mer counting | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | MAPREDUCE | Distributed computing | COMPUTATIONAL BIOLOGY | Apache Spark
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2009, Volume 32, Issue 6, pp. 1007 - 1022
Abstract We characterized the gene expression profile of brain regions at an early stage of the Alzheimer's like neurodegeneration in the anti-NGF AD11 model....
Neurology | Internal Medicine | Early inflammation | Immune response | NGF | Alzheimer's disease | AD11 mice | NERVE-GROWTH-FACTOR | ALZHEIMERS-DISEASE | MODEL | SYNAPTIC PLASTICITY | NEUROSCIENCES | CELL-DEATH | GERIATRICS & GERONTOLOGY | A-BETA | NEURONS | BASAL FOREBRAIN | LONG-TERM POTENTIATION | EXPRESSION | RNA, Messenger - immunology | Alzheimer Disease - complications | Age Factors | Antibodies - metabolism | Neurodegenerative Diseases - etiology | Gene Expression Profiling | Nerve Growth Factors - metabolism | RNA, Messenger - metabolism | Wnt Proteins - metabolism | Choline O-Acetyltransferase - metabolism | Alzheimer Disease - pathology | Brain - metabolism | Inflammation - metabolism | Wnt Proteins - genetics | Nerve Growth Factor - immunology | Statistics, Nonparametric | Alzheimer Disease - immunology | Choline O-Acetyltransferase - genetics | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Neurodegenerative Diseases - pathology | Receptors, Cholinergic - metabolism | Oligonucleotide Array Sequence Analysis - methods | Mice, Transgenic | Neurodegenerative Diseases - genetics | Signal Transduction - genetics | Inflammation - etiology | Animals | Analysis of Variance | Nerve Growth Factors - genetics | Inflammation - genetics | Antibodies - genetics | Mice | Alzheimer Disease - genetics | Brain - immunology | Receptors, Cholinergic - genetics | Nervous system diseases | DNA microarrays | Messenger RNA | Analysis | Genes | Amyloid beta-protein | Nerve growth factor | Inflammation | Gene expression
Neurology | Internal Medicine | Early inflammation | Immune response | NGF | Alzheimer's disease | AD11 mice | NERVE-GROWTH-FACTOR | ALZHEIMERS-DISEASE | MODEL | SYNAPTIC PLASTICITY | NEUROSCIENCES | CELL-DEATH | GERIATRICS & GERONTOLOGY | A-BETA | NEURONS | BASAL FOREBRAIN | LONG-TERM POTENTIATION | EXPRESSION | RNA, Messenger - immunology | Alzheimer Disease - complications | Age Factors | Antibodies - metabolism | Neurodegenerative Diseases - etiology | Gene Expression Profiling | Nerve Growth Factors - metabolism | RNA, Messenger - metabolism | Wnt Proteins - metabolism | Choline O-Acetyltransferase - metabolism | Alzheimer Disease - pathology | Brain - metabolism | Inflammation - metabolism | Wnt Proteins - genetics | Nerve Growth Factor - immunology | Statistics, Nonparametric | Alzheimer Disease - immunology | Choline O-Acetyltransferase - genetics | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Neurodegenerative Diseases - pathology | Receptors, Cholinergic - metabolism | Oligonucleotide Array Sequence Analysis - methods | Mice, Transgenic | Neurodegenerative Diseases - genetics | Signal Transduction - genetics | Inflammation - etiology | Animals | Analysis of Variance | Nerve Growth Factors - genetics | Inflammation - genetics | Antibodies - genetics | Mice | Alzheimer Disease - genetics | Brain - immunology | Receptors, Cholinergic - genetics | Nervous system diseases | DNA microarrays | Messenger RNA | Analysis | Genes | Amyloid beta-protein | Nerve growth factor | Inflammation | Gene expression
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 3, pp. 885 - 893
GABA, the main inhibitory transmitter in adulthood, early in postnatal development exerts a depolarizing and excitatory action. This effect, which results from...
FOREBRAIN CHOLINERGIC NEURONS | TEMPORAL-LOBE EPILEPSY | RAT BASAL FOREBRAIN | ALZHEIMERS-DISEASE | CHLORIDE HOMEOSTASIS | NGF TRANSGENIC MICE | CL-COTRANSPORTER KCC2 | EXCITATORY ACTIONS | SYNAPTIC EFFICACY | MONOCLONAL-ANTIBODIES | NEUROSCIENCES | Sodium Potassium Chloride Symporter Inhibitors - pharmacology | gamma-Aminobutyric Acid - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Pyridazines - pharmacology | RNA, Messenger - metabolism | Excitatory Postsynaptic Potentials - drug effects | Isonicotinic Acids - pharmacology | Excitatory Postsynaptic Potentials - physiology | Quinoxalines - pharmacology | Nerve Growth Factor - antagonists & inhibitors | Nerve Growth Factor - immunology | Neurons - physiology | Neurons - drug effects | Electric Stimulation - methods | Excitatory Postsynaptic Potentials - genetics | Receptors, Nicotinic - metabolism | Gene Expression Regulation - genetics | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Antibodies, Neutralizing - genetics | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Hippocampus - cytology | Bumetanide - pharmacology | Symporters - metabolism | GABA Antagonists - pharmacology | Gene Expression Regulation - drug effects | Patch-Clamp Techniques | Animals | Ion Channel Gating - genetics | GABA Agonists - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Mice | Hippocampus - physiology | In Vitro Techniques | Receptors, Nicotinic - genetics | Ion Channel Gating - drug effects
FOREBRAIN CHOLINERGIC NEURONS | TEMPORAL-LOBE EPILEPSY | RAT BASAL FOREBRAIN | ALZHEIMERS-DISEASE | CHLORIDE HOMEOSTASIS | NGF TRANSGENIC MICE | CL-COTRANSPORTER KCC2 | EXCITATORY ACTIONS | SYNAPTIC EFFICACY | MONOCLONAL-ANTIBODIES | NEUROSCIENCES | Sodium Potassium Chloride Symporter Inhibitors - pharmacology | gamma-Aminobutyric Acid - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Pyridazines - pharmacology | RNA, Messenger - metabolism | Excitatory Postsynaptic Potentials - drug effects | Isonicotinic Acids - pharmacology | Excitatory Postsynaptic Potentials - physiology | Quinoxalines - pharmacology | Nerve Growth Factor - antagonists & inhibitors | Nerve Growth Factor - immunology | Neurons - physiology | Neurons - drug effects | Electric Stimulation - methods | Excitatory Postsynaptic Potentials - genetics | Receptors, Nicotinic - metabolism | Gene Expression Regulation - genetics | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Antibodies, Neutralizing - genetics | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Hippocampus - cytology | Bumetanide - pharmacology | Symporters - metabolism | GABA Antagonists - pharmacology | Gene Expression Regulation - drug effects | Patch-Clamp Techniques | Animals | Ion Channel Gating - genetics | GABA Agonists - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Mice | Hippocampus - physiology | In Vitro Techniques | Receptors, Nicotinic - genetics | Ion Channel Gating - drug effects
Journal Article