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Chemical communications (Cambridge, England), ISSN 1359-7345, 05/2019, Volume 55, Issue 44, pp. 6217 - 6220
Transient binding events are a challenging issue in enzymology. Here we demostrate a time-based ITC approach to human flavin-containing monooxygenase 3, an... 
Journal Article
ISSN 1359-7345, 5/2019, Volume 55, Issue 44, pp. 6217 - 622
Transient binding events are a challenging issue in enzymology. Here we demostrate a time-based ITC approach to human flavin-containing monooxygenase 3, an... 
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2019, Volume 55, Issue 44, pp. 6217 - 6220
Transient binding events are a challenging issue in enzymology. Here we demostrate a time-based ITC approach to human flavin-containing monooxygenase 3, an... 
Trimethylamine | Enzymology | Substrates
Journal Article
Journal Article
New BIOTECHNOLOGY, ISSN 1871-6784, 01/2020, Volume 54, pp. 71 - 79
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 09/2016, Volume 1864, Issue 9, pp. 1177 - 1187
Ar-BVMO is a recently discovered Baeyer-Villiger monooxygenase from the genome of Acinetobacter radioresistens S13 closely related to medically relevant... 
Drug metabolites | BVMO | Ethionamide | Flavoprotein | Isothermal calorimetry | Stopped-flow | MYCOBACTERIUM-TUBERCULOSIS | BIOCATALYSTS | HALF-REACTION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRODRUG ACTIVATOR ETAA | CYCLOHEXANONE MONOOXYGENASE | CONTAINING MONO-OXYGENASE | ACINETOBACTER-RADIORESISTENS | BIOPHYSICS | HYDROGEN-PEROXIDE | FLAVIN-CONTAINING MONOOXYGENASE | Glycine - metabolism | Bacterial Proteins - chemistry | Substrate Specificity | Alanine - chemistry | Mixed Function Oxygenases - metabolism | Mixed Function Oxygenases - chemistry | Ethionamide - metabolism | Acinetobacter - enzymology | Glycine - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Catalytic Domain | Gene Expression | Biocatalysis | Mutagenesis, Site-Directed | Oxidation-Reduction | Soil Microbiology | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Acinetobacter - genetics | Alanine - metabolism | Recombinant Proteins - genetics | Arginine - chemistry | Sequence Homology, Amino Acid | Ethionamide - chemistry | Sequence Alignment | Escherichia coli - genetics | Ketones - chemistry | Bacterial Proteins - metabolism | Flavins - chemistry | Kinetics | Mutation | Mixed Function Oxygenases - genetics | Ketones - metabolism | Arginine - metabolism | Flavins - metabolism | Enzymes | Genetic aspects | Liquid chromatography | Metabolites | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2019, Volume 145, pp. 250 - 255
Human flavin-containing monooxygenase 3 (hFMO3) is a drug-metabolizing enzyme capable of performing N- or S-oxidation using the C4a-hydroperoxy intermediate.... 
Uncoupling | Flavin-containing monooxygenase | Hydrogen peroxide | Superoxide radical | N61S | Polymorphic variant | OXIDATION | ACTIVATION | HALF-REACTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FMO3 | GENE | AMINES | ENZYMES | ENDOCRINOLOGY & METABOLISM | DRUG-METABOLISM
Journal Article
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 11/2019, Volume 140, pp. 577 - 587
Class VII cytochromes P450 are self-sufficient enzymes carrying a phthalate family oxygenase-like reductase domain and a P450 domain fused in a single... 
X-ray crystallography | Peroxide shunt | Cytochrome P450 | REDOX POTENTIALS | COMPLEX | POLYMER SCIENCE | ENVIRONMENTS | STRUCTURE REFINEMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-SUFFICIENT CYTOCHROME-P450 | MODEL | MONOOXYGENASES | SUBSTRATE | CHEMISTRY, APPLIED | PEROXIDE-DRIVEN HYDROXYLATION | BINDING
Journal Article
Electrochimica Acta, ISSN 0013-4686, 02/2017, Volume 228, p. 611
Genetic variation of phase I drug metabolising enzymes has been shown to greatly influence inter-individual reaction to pharmacological treatments. Among these... 
Enzymes | Pharmacology | Metabolism | Tamoxifen | Glassy carbon | Substrates | Electrodes | Electrocatalysis | Metabolites | Graphene | Electrochemistry | Oxygenation | Polymorphism
Journal Article