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Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 1337 - 1337
Journal Article
Cancer Letters, ISSN 0304-3835, 04/2017, Volume 392, pp. 51 - 59
Mitogen-activated protein kinases (MAPKs) regulate diverse cellular processes including proliferation, cell survival, differentiation, and apoptosis. While... 
Targeted therapies | Mitogen-activated protein kinase | Cellular signaling | Kinase inhibitors | MEK5-ERK5 | PROTEIN-KINASE KINASE | DIFFERENTIAL REGULATION | REGULATED KINASE-5 | NUCLEAR TRANSLOCATION | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER CELLS | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | PROSTATE-CANCER | GENE-EXPRESSION | NF-KAPPA-B | Neoplasms - metabolism | Proto-Oncogene Proteins - metabolism | Cell Proliferation | Humans | Drug Resistance, Neoplasm | MAP Kinase Kinase 5 - antagonists & inhibitors | Proto-Oncogene Proteins - genetics | Antineoplastic Agents - therapeutic use | MAP Kinase Kinase 5 - genetics | Mitogen-Activated Protein Kinase 7 - metabolism | Molecular Targeted Therapy | Neoplasms - drug therapy | Animals | Neoplasms - genetics | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | MAP Kinase Kinase 5 - metabolism | Cell Differentiation | Mutation | Neoplasms - pathology | Apoptosis | Metastasis | Drug resistance | Cell differentiation | Mitogens | Protein kinases | Pharmacy | Medical research | Phosphorylation | Leukemia | Multiple myeloma | Breast cancer | Kinases | Cell adhesion & migration | Esophagus | Proteins | Signal transduction | Liver cancer | Cell growth | Epidermal growth factor | Cell cycle | Tumor necrosis factor-TNF | Tumorigenesis | Drug dosages | Prostate
Journal Article
Blood, ISSN 0006-4971, 10/2018, Volume 132, Issue 17, pp. 1737 - 1749
The Primary Immune Deficiency Treatment Consortium (PIDTC) performed a retrospective analysis of 662 patients with severe combined immunodeficiency (SCID) who... 
CRITERIA | SEVERE COMBINED IMMUNODEFICIENCY | BONE-MARROW-TRANSPLANTATION | DISEASE | HCT | EXPERIENCE | COHORT | STEM-CELL TRANSPLANTATION | HEMATOLOGY | RECONSTITUTION | Plenary Paper | 100
Journal Article
Journal of cellular biochemistry, ISSN 0730-2312, 08/2019
Triple-negative breast cancers (TNBCs) represent 15% to 20% of all breast cancers and are often associated with poor prognosis. The lack of targeted therapies... 
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 2392 - 2392
Journal Article
Cancer Letters, ISSN 0304-3835, 2017, Volume 392, pp. 51 - 59
Abstract Mitogen-activated protein kinases (MAPKs) regulate diverse cellular processes including proliferation, cell survival, differentiation, and apoptosis.... 
Hematology, Oncology and Palliative Medicine | mitogen-activated protein kinase | cellular signaling | kinase inhibitors | targeted therapies | MEK5-ERK5
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 967 - 967
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2018, Volume 28, Issue 13, pp. 2294 - 2301
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.bmcl.2018.05.029 
MEDICINAL CHEMISTRY | CELLS | CROSS-COUPLING REACTIONS | CHEMISTRY, MEDICINAL | HALOGEN BONDS | ERK5 | CHEMISTRY, ORGANIC | COPPER | INHIBITORS | MICROWAVE-ASSISTED SYNTHESIS | MEK5/ERK5 PATHWAY | ALKYNE CYCLOADDITION | Drugstores | Surface active agents | Protein kinases | Mitogens | Pharmacy
Journal Article
FRONTIERS IN ONCOLOGY, ISSN 2234-943X, 07/2019, Volume 9, p. 672
Epithelial to mesenchymal transition (EMT) is a cellular program that converts nonmotile epithelial cells into invasive mesenchymal cells. EMT is implicated in... 
CELLS | ONCOLOGY | mesenchymal | RESISTANCE | FLUORINE | TNBC | MAPK | MET | EMT | EXPRESSION | phenotypic switch | INSIGHTS | Molecular targeted therapy | Care and treatment | Usage | Epithelial cells | Development and progression | Breast cancer | Genetic aspects | Research | Tamoxifen | Stem cells
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 260 - 260
Abstract The X-linked disorder Wiskott-Aldrich Syndrome (WAS), characterized by thrombocytopenia, eczema, recurrent infections, autoimmunity and cancer, is... 
Journal Article
02/2019
Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
04/2016
Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
05/2015
Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
03/2015
Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES | ACYCLIC OR CARBOCYCLIC COMPOUNDS
Patent
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