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Nature medicine, ISSN 1078-8956, 11/2014, Volume 20, Issue 11, pp. 1301 - 1309
Some of the anti-neoplastic effects of anthracyclines in mice originate from the induction of innate and T cell-mediated anticancer immune responses. Here we... 
MEDICINE, RESEARCH & EXPERIMENTAL | DOUBLE-STRANDED-RNA | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE | RIG-I | TUMORS | CELL BIOLOGY | TOLL-LIKE RECEPTOR-3 | BREAST-CANCER | ANTICANCER CHEMOTHERAPY | GENE | IMMUNE-RESPONSES | Doxorubicin - therapeutic use | Breast Neoplasms - immunology | Humans | RNA, Messenger - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Interferon Type I - biosynthesis | Receptors, Pattern Recognition - metabolism | Neoplasm Metastasis | Anthracyclines - pharmacology | Interferon Type I - metabolism | Female | Neoadjuvant Therapy | Gene Expression Regulation, Neoplastic - drug effects | RNA - metabolism | Receptor, Interferon alpha-beta - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Treatment Outcome | Toll-Like Receptor 3 - metabolism | Breast Neoplasms - drug therapy | Animals | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Immunocompetence - drug effects | Anthracyclines - therapeutic use | Chemokine CXCL10 - metabolism | Myxovirus Resistance Proteins - metabolism | Doxorubicin - pharmacology | Anthracyclines | Care and treatment | Analysis | Physiological aspects | Interferon | Research | Cancer | Signal transduction | Chemotherapy | Breast cancer | Chemokines | Life Sciences | Immunology | Immunotherapy
Journal Article
Science, ISSN 0036-8075, 11/2015, Volume 350, Issue 6263, pp. 972 - 978
Journal Article
Nature Medicine, ISSN 1078-8956, 2011, Volume 17, Issue 6, pp. 700 - 707
The natural killer (NK) cell receptor NKp30 is involved in the recognition of tumor and dendritic cells (DCs). Here we describe the influence of three NKp30... 
MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL-KILLER-CELLS | HUMAN DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IL-10 PRODUCTION | C-KIT | TRIGGERING RECEPTOR | CELL BIOLOGY | NK CELLS | CLASS-III | CYTOTOXICITY RECEPTORS | HUMAN MHC | EXPRESSION | Prognosis | Alternative Splicing - genetics | Humans | Interleukin-12 - physiology | Lysosomal-Associated Membrane Protein 1 - physiology | Interferon-gamma - physiology | Alternative Splicing - physiology | Gastrointestinal Stromal Tumors - physiopathology | Natural Cytotoxicity Triggering Receptor 3 - genetics | Natural Cytotoxicity Triggering Receptor 3 - physiology | Killer Cells, Natural - physiology | Proto-Oncogene Proteins c-kit - physiology | Gastrointestinal Stromal Tumors - diagnosis | Protein Isoforms | Tumor Necrosis Factor-alpha - physiology | Cell Line, Tumor | Polymorphism, Single Nucleotide - genetics | Proto-Oncogene Proteins c-kit - genetics | Gastrointestinal Stromal Tumors - genetics | Dendritic cells | Gastrointestinal tumors | Physiological aspects | Genetic aspects | Research | Gene expression | Interferon | Medical prognosis | Gastrointestinal diseases | Tumors | Cancer | Interferon-gamma | Killer Cells, Natural | Alternative Splicing | Natural Cytotoxicity Triggering Receptor 3 | Interleukin-12 | Proto-Oncogene Proteins c-kit | Tumor Necrosis Factor-alpha | Life Sciences | Lysosomal-Associated Membrane Protein 1 | Immunology | Polymorphism, Single Nucleotide | Gastrointestinal Stromal Tumors
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2015, Volume 34, Issue 8, pp. 1025 - 1041
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 06/2013, Volume 73, Issue 12, pp. 3499 - 3510
Cancer immunosurveillance relies on effector/memory tumor-infiltrating CD8(+) T cells with a T-helper cell 1 (T(H)1) profile. Evidence for a natural killer... 
NATURAL-KILLER-CELLS | INHIBITION | EFFICACY | ONCOLOGY | C-KIT | MUTATIONS | CYTOTOXIC ACTIVITY | CANCER | EXPRESSION | IMATINIB MESYLATE | PREDICTION | Forkhead Transcription Factors - immunology | Immunohistochemistry | Multivariate Analysis | Pyrimidines - immunology | Prognosis | Humans | Middle Aged | Male | Benzamides - therapeutic use | Flow Cytometry | T-Lymphocytes - metabolism | Forkhead Transcription Factors - metabolism | Protein Kinase Inhibitors - immunology | T-Lymphocytes - drug effects | Aged, 80 and over | Killer Cells, Natural - immunology | Adult | Female | Lymphocytes, Tumor-Infiltrating - metabolism | CD56 Antigen - immunology | Natural Cytotoxicity Triggering Receptor 1 - immunology | Gastrointestinal Stromal Tumors - immunology | CD56 Antigen - metabolism | Kaplan-Meier Estimate | Treatment Outcome | Piperazines - therapeutic use | Lymphocytes, Tumor-Infiltrating - drug effects | Benzamides - immunology | CD3 Complex - metabolism | Imatinib Mesylate | Gastrointestinal Stromal Tumors - drug therapy | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | CD3 Complex - immunology | Piperazines - immunology | Gastrointestinal Stromal Tumors - metabolism | Natural Cytotoxicity Triggering Receptor 1 - metabolism | T-Lymphocytes - immunology | Aged | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Cohort Studies | Lymphocytes, Tumor-Infiltrating - immunology
Journal Article
by Galluzzi, Lorenzo and Vitale, Ilio and Senovilla, Laura and Olaussen, Ken André and Pinna, Guillaume and Eisenberg, Tobias and Goubar, Aïcha and Martins, Isabelle and Michels, Judith and Kratassiouk, Gueorgui and Carmona-Gutierrez, Didac and Scoazec, Marie and Vacchelli, Erika and Schlemmer, Frederic and Kepp, Oliver and Shen, Shensi and Tailler, Maximilien and Niso-Santano, Mireia and Morselli, Eugenia and Criollo, Alfredo and Adjemian, Sandy and Jemaà, Mohamed and Chaba, Kariman and Pailleret, Claire and Michaud, Mickaël and Pietrocola, Federico and Tajeddine, Nicolas and de La Motte Rouge, Thibault and Araujo, Natalia and Morozova, Nadya and Robert, Thomas and Ripoche, Hugues and Commo, Frederic and Besse, Benjamin and Validire, Pierre and Fouret, Pierre and Robin, Angélique and Dorvault, Nicolas and Girard, Philippe and Gouy, Sébastien and Pautier, Patricia and Jägemann, Nora and Nickel, Ann-Christin and Marsili, Sabrina and Paccard, Caroline and Servant, Nicolas and Hupé, Philippe and Behrens, Carmen and Behnam-Motlagh, Parviz and Kohno, Kimitoshi and Cremer, Isabelle and Damotte, Diane and Alifano, Marco and Midttun, Øivind and Ueland, Per Magne and Lazar, Vladimir and Dessen, Philippe and Zischka, Hans and Chatelut, Etienne and Castedo, Maria and Madeo, Frank and Barillot, Emmanuel and Thomale, Juergen and Wistuba, Ignacio Ivan and Sautès-Fridman, Catherine and Zitvogel, Laurence and Soria, Jean-Charles and Harel-Bellan, Annick and Kroemer, Guido and Medicinska fakulteten and Klinisk kemi and Institutionen för medicinsk biovetenskap and Umeå universitet
Cell Reports, ISSN 2211-1247, 08/2012, Volume 2, Issue 2, pp. 257 - 269
Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we... 
ALK | MITOCHONDRIAL-MEMBRANE PERMEABILIZATION | APOPTOSIS | CELLS | INHIBITION | INFLAMMATION | KINASE | DEATH | GROWTH-FACTOR | P53 | CELL BIOLOGY | Gene Expression Regulation, Enzymologic - drug effects | Lung Neoplasms - drug therapy | Pyridoxal Kinase - genetics | Apoptosis - drug effects | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Middle Aged | Apoptosis - genetics | Lung Neoplasms - pathology | Male | Antineoplastic Agents - administration & dosage | Pyridoxal Kinase - biosynthesis | Vitamin B 6 - genetics | Cisplatin - administration & dosage | Aged, 80 and over | Adult | Female | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Genome-Wide Association Study | Vitamin B 6 - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Neoplasm Proteins - biosynthesis | Carcinoma, Non-Small-Cell Lung - metabolism | Survival Rate | Carcinoma, Non-Small-Cell Lung - mortality | Disease-Free Survival | Animals | Gene Expression Regulation, Enzymologic - genetics | Aged | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Cohort Studies | Biological Sciences | Naturvetenskap | Natural Sciences | Cellbiologi | Biologiska vetenskaper | Cell Biology
Journal Article
Journal Article