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Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 2926 - 2926
Abstract Background Severe cytopenias in CLL are typically associated with bone marrow failure due to massive infiltration of the bone marrow by leukemic cells... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 5585 - 5585
Abstract INTRODUCTION: The prevalence of liver dysfunction in patients with previously untreated chronic lymphocytic leukemia (CLL) is unknown; knowledge of... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3228 - 3228
Abstract Background: Individuals with clinically ascertained monoclonal B-cell lymphocytosis (c-MBL) having the phenotype of the chronic lymphocytic leukemia... 
Journal Article
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 06/2018, Volume 319, Issue 23, pp. 2401 - 2409
Journal Article
by Berndt, Sonja I and Camp, Nicola J and Skibola, Christine F and Vijai, Joseph and Wang, Zhaoming and Gu, Jian and Nieters, Alexana and Kelly, Rachel S and Smedby, Karin E and Monnereau, Alain and Cozen, Wendy and Cox, Angela and Wang, Sophia S and Lan, Qing and Teras, Lauren R and Machado, Moara and Yeager, Meredith and Brooks-Wilson, Angela R and Hartge, Patricia and Purdue, Mark P and Birmann, Brenda M and Vajdic, Claire M and Cocco, Pierluigi and Zhang, Yawei and Giles, Graham G and Zeleniuch-Jacquotte, Anne and Lawrence, Charles and Montalvan, Rebecca and Burdett, Laurie and Hutchinson, Amy and Ye, Yuanqing and Call, Timothy G and Shanafelt, Tait D and Novak, Anne J and Kay, Neil E and Liebow, Mark and Cunningham, Julie M and Allmer, Cristine and Hjalgrim, Henrik and Adami, Hans-Olov and Melbye, Mads and Glimelius, Bengt and Chang, Ellen T and Glenn, Martha and Curtin, Karen and Cannon-Albright, Lisa A and Diver, W Ryan and Link, Brian K and Weiner, George J and Conde, Lucia and Bracci, Paige M and Riby, Jacques and Arnett, Donna K and Zhi, Degui and Leach, Justin M and Holly, Elizabeth A and Jackson, Rebecca D and Tinker, Lesley F and Benavente, Yolanda and Sala, Núria and Casabonne, Delphine and Becker, Nikolaus and Boffetta, Paolo and Brennan, Paul and Foretova, Lenka and Maynadie, Marc and McKay, James and Staines, Anthony and Chaffee, Kari G and Achenbach, Sara J and Vachon, Celine M and Goldin, Lynn R and Strom, Sara S and Leis, Jose F and Weinberg, J Brice and Caporaso, Neil E and Norman, Aaron D and De Roos, Anneclaire J and Morton, Lindsay M and Severson, Richard K and Riboli, Elio and Vineis, Paolo and Kaaks, Rudolph and Masala, Giovanna and Weiderpass, Elisabete and Chirlaque, María-Dolores and Vermeulen, Roel C H and Travis, Ruth C and Southey, Melissa C and Milne, Roger L and Albanes, Demetrius and Virtamo, Jarmo and Weinstein, Stephanie and Clavel, Jacqueline and Zheng, Tongzhang and Holford, Theodore R and Villano, Danylo J and Maria, Ann and Spinelli, John J and Gascoyne, Randy D and ... and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Experimentell och klinisk onkologi
Nature Communications [E], ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 10933
Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and... 
Membrane Proteins | Adaptor Proteins, Signal Transducing | Genetic Predisposition to Disease | Genome-Wide Association Study | Apoptosis Regulatory Proteins | Humans | Serpins | European Continental Ancestry Group | Polymorphism, Single Nucleotide | Proto-Oncogene Proteins | T-Box Domain Proteins | Leukemia, Lymphocytic, Chronic, B-Cell | VARIANTS | BANK1 | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | RISK | CLASSIFICATION | FAS GENE-MUTATIONS | FOLLICULAR LYMPHOMA | PRIORITIZATION | COMMON VARIATION | IDENTIFICATION | European Continental Ancestry Group - genetics | Serpins - genetics | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | T-Box Domain Proteins - genetics | Bcl-2-Like Protein 11 | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - genetics | Chronic lymphatic leukemia | Leukemia | Agent orange | Genomes | Single-nucleotide polymorphism | Malignancy | Lymphatic leukemia | Chromosome 4 | Chromosome 3 | Loci | Chromosome 2 | Heritability | Apoptosis | Samfunnsmedisin, sosialmedisin: 801 | Community medicine, Social medicine: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Life Sciences | Hematology | Human health and pathology | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 8, pp. 911 - 916
Journal Article
by Klein, Alison P and Wolpin, Brian M and Risch, Harvey A and Stolzenberg-Solomon, Rachael Z and Mocci, Evelina and Zhang, Mingfeng and Canzian, Federico and Childs, Erica J and Hoskins, Jason W and Jermusyk, Ashley and Zhong, Jun and Chen, Fei and Albanes, Demetrius and Aneotti, Gabriella and Arslan, Alan A and Babic, Ana and Bamlet, William R and Beane-Freeman, Laura and Berndt, Sonja I and Blackford, Amanda and Borges, Michael and Borgida, Ayelet and Bracci, Paige M and Brais, Lauren and Brennan, Paul and Brenner, Hermann and Bueno-de-Mesquita, Bas and Buring, Julie and Campa, Daniele and Capurso, Gabriele and Cavestro, Giulia Martina and Chaffee, Kari G and Chung, Charles C and Cleary, Sean and Cotterchio, Michelle and Dijk, Frederike and Duell, Eric J and Foretova, Lenka and Fuchs, Charles and Funel, Niccola and Gallinger, Steven and M Gaziano, J. Michael and Gazouli, Maria and Giles, Graham G and Giovannucci, Edward and Goggins, Michael and Goodman, Gary E and Goodman, Phyllis J and Hackert, Thilo and Haiman, Christopher and Hartge, Patricia and Hasan, Manal and Hegyi, Peter and Helzlsouer, Kathy J and Herman, Joseph and Holcatova, Ivana and Holly, Elizabeth A and Hoover, Robert and Hung, Rayjean J and Jacobs, Eric J and Jamroziak, Krzysztof and Janout, Vladimir and Kaaks, Rudolf and Khaw, Kay-Tee and Klein, Eric A and Kogevinas, Manolis and Kooperberg, Charles and Kulke, Matthew H and Kupcinskas, Juozas and Kurtz, Robert J and Laheru, Daniel and Landi, Stefano and Lawlor, Rita T and Lee, I.-Min and Lemarchand, Loic and Lu, Lingeng and Malats, Núria and Mambrini, Anea and Mannisto, Satu and Milne, Roger L and Mohelníková-Duchoňová, Beatrice and Neale, Rachel E and Neoptolemos, John P and Oberg, Ann L and Olson, Sara H and Orlow, Irene and Pasquali, Claudio and Patel, Alpa V and Peters, Ulrike and Pezzilli, Raffaele and Porta, Miquel and Real, Francisco X and Rothman, Nathaniel and Scelo, Ghislaine and Sesso, Howard D and Severi, Gianluca and Shu, Xiao-Ou and Silverman, Debra and Smith, Jill P and Soucek, Pavel and ... and Medicinska fakulteten and Kirurgi and Institutionen för kirurgisk och perioperativ vetenskap and Umeå universitet
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 556 - 11
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 3022 - 3022
Monoclonal B cell lymphocytosis (MBL) has been shown to be the precursor condition that precedes overt diagnosis of chronic lymphocytic leukemia (CLL). Whereas... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2016, Volume 34, Issue 16, pp. 1898 - 1904
Purpose The inclusion of metformin in the treatment arms of cancer clinical trials is based on improved survival that has been demonstrated in retrospective... 
ONCOLOGY | RISK | IMMORTAL TIME BIAS | Metformin - therapeutic use | Humans | Middle Aged | Proportional Hazards Models | Male | Aged, 80 and over | Adult | Carcinoma, Pancreatic Ductal - mortality | Female | Aged | Pancreatic Neoplasms - mortality | Retrospective Studies | Adenocarcinoma - mortality | Gic22 | Bios4 | Stat | ORIGINAL REPORTS
Journal Article
Cancer, ISSN 0008-543X, 09/2015, Volume 121, Issue 17, pp. 2883 - 2891
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1833 - 1833
Abstract The characteristic clinical heterogeneity observed in chronic lymphocytic leukemia (CLL) reflects its biological diversity and as a consequence,... 
Journal Article