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Advances in pharmacology (San Diego, Calif.), 2019, Volume 86, p. 97
Abnormalities of glutamatergic transmission are implicated in neuropsychiatric disorders. Among the glutamate receptors, metabotropic (mGlu) 2/3 receptors have... 
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 6/2014, Volume 231, Issue 11, pp. 2291 - 2298
α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor stimulation has been proposed to be a common neural mechanism of metabotropic glutamate... 
Neurosciences | AMPA receptor | Biomedicine | Ketamine | Serotonin | Metabotropic glutamate 2/3 receptor antagonist | Depression | Pharmacology/Toxicology | Psychiatry | 5-HT1A receptor | Novelty-suppressed feeding test | 5-HT1Areceptor | ANTIDEPRESSANT | Novelty-suppressedfeedingtest | RESISTANT MAJOR DEPRESSION | 5-HT1A RECEPTORS | PSYCHIATRY | INVOLVEMENT | RELEASE | NEUROSCIENCES | PREFRONTAL CORTEX | MGS0039 | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | MICE | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Serotonin 5-HT1 Receptor Antagonists - pharmacology | Receptors, N-Methyl-D-Aspartate - metabolism | Male | Receptors, Metabotropic Glutamate - metabolism | Amino Acids - pharmacology | Quinoxalines - pharmacology | Piperidines - pharmacology | Dioxoles - pharmacology | Antidepressive Agents - pharmacology | Ritanserin - pharmacology | Fenclonine - pharmacology | Receptors, AMPA - metabolism | Tryptophan Hydroxylase - metabolism | Xanthenes - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Serotonin 5-HT2 Receptor Antagonists - pharmacology | Piperazines - pharmacology | Feeding Behavior - physiology | Feeding Behavior - drug effects | Neuropsychological Tests | Animals | Pyridines - pharmacology | Ketamine - pharmacology | Tryptophan Hydroxylase - antagonists & inhibitors | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Receptors, AMPA - antagonists & inhibitors | Neurons | Amino acids
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 09/2014, Volume 271, pp. 111 - 115
Ketamine, a non-competitive -methyl- -aspartate receptor antagonist, and group II metabotropic glutamate (mGlu2/3) receptor antagonists produce antidepressant... 
AMPA receptor | Forced swim test | Ketamine | LY341495 | mGlu2/3 receptor | MGlu2/3 receptor | MAMMALIAN TARGET | RAPAMYCIN | INVOLVEMENT | ADD-ON TRIAL | MECHANISMS | D-ASPARTATE ANTAGONIST | NEUROSCIENCES | GLUTAMATERGIC TRANSMISSION | BIPOLAR DEPRESSION | ANIMAL-MODELS | BEHAVIORAL SCIENCES | WORKING-MEMORY | Antidepressants
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 10/2011, Volume 224, Issue 1, pp. 107 - 111
► Ketamine exerts the rapid antidepressant effect in the learned helplessness test. ► Ketamine exerts the sustained antidepressant effect in the tail... 
Antidepressant | AMPA receptor | Learned helplessness paradigm | Ketamine | Tail suspension test | NMDA RECEPTOR | ANTERIOR CINGULATE CORTEX | ACID | BEHAVIORAL DESPAIR | METABOTROPIC GLUTAMATE RECEPTORS | MECHANISMS | D-ASPARTATE ANTAGONIST | MAJOR DEPRESSION | NEUROSCIENCES | MOOD DISORDERS | BEHAVIORAL SCIENCES | MICE | Models | Antidepressants | Analysis | Depression, Mental
Journal Article
Pharmaceuticals, ISSN 1424-8247, 09/2015, Volume 8, Issue 3, pp. 590 - 606
Recently, ketamine has been demonstrated to exert rapid-acting antidepressant effects in patients with depression, including those with treatment-resistant... 
GLYX-13 | Ketamine | mGlu2/3 antagonist | mGlu5 antagonist | GluN2B antagonist | Studies | Mental depression | Antidepressants | Patients | ketamine
Journal Article
Journal Article