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by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and Rayner, N. William and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Anew T and van Dam, Rob M and Doney, Alex S. F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and DIAbet Genetics Replication Meta-A and the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten and Stockholms universitet and Science for Life Laboratory (SciLifeLab)
Nature genetics, ISSN 1061-4036, 2015, Volume 47, Issue 12, pp. 1415 - +
Journal Article
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9813, pp. 384 - 384
Journal Article
Atherosclerosis, ISSN 0021-9150, 2016, Volume 250, pp. 95 - 105
Abstract Background and aims Coronary artery disease (CAD) risk is associated with non-coding genetic variants at the phosphatase and actin regulating protein... 
Cardiovascular | Myocardial infarction | Expression quantitative trait locus (eQTL) | Oxidized low density lipoprotein (oxLDL) | Low-density lipoprotein (LDL) | Genomics | Atherosclerosis | Genetic polymorphism | PHACTR1 | Functional genomics | Genetic disease | CELLS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | VARIANTS | MACROPHAGES | IDENTIFICATION | PATHOGENESIS | PERIPHERAL VASCULAR DISEASE | PROTEINS | EXPRESSION | CORONARY-ARTERY-DISEASE | GENOME-WIDE ASSOCIATION | Coronary Vessels - pathology | Atherosclerosis - genetics | Humans | Middle Aged | Gene Expression Regulation | Genotype | Inflammation | Gene-Environment Interaction | Young Adult | Tumor Necrosis Factor-alpha - pharmacology | Macrophages - metabolism | Muscle, Smooth, Vascular - pathology | Coronary Artery Disease - diagnosis | Endothelial Cells - cytology | Alleles | Coronary Artery Disease - genetics | Lipopolysaccharides - pharmacology | Atherosclerosis - diagnosis | Adult | Aged | Microfilament Proteins - metabolism | Polymorphism, Single Nucleotide | Microfilament Proteins - genetics | Phosphatases | Actin | Genes | Genetic aspects | Genetic transcription | Muscle proteins | Binding proteins | Coronary heart disease | Risk factors | Cells | Protein binding | Index Medicus | DAB, diaminobenzidine | PBMC, peripheral blood mononuclear cells | NLS, nuclear localization signal | CAD, coronary artery disease | HAEC, human aortic endothelial cells | oxLDL, oxidized low density lipoprotein | PP1, protein phosphatase 1 | SNP, single nucleotide polymorphism | RACE, rapid amplification of cDNA ends | LPS, lipopolysaccharide | GWAS, genome wide association studies | PHACTR1, phosphatase and actin regulator 1 | TSS, transcription start site
Journal Article
by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and Rayner, N William and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Andrew T and van Dam, Rob M and Doney, Alex S F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nature genetics, 12/2015, Volume 47, Issue 12, p. 1415
Journal Article
by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and William Rayner, N and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Anew T and van Dam, Rob M and Doney, Alex S F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 12, p. 1415
We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct... 
Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Gaulton, Kyle and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and Rayner, Nigel William and Robertson, Neil and Scott, Robert and Prokopenko, Inga and Scott, Laura and Green, Todd and Sparsø, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart and Leeuwen, Elisa and Willems, Sara and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin and Abecasis, Gonçalo and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori and Bottinger, Erwin P and Burtt, Noël and Carey, Jason and Charpentier, Guillaume and Chines, Peter and Cornelis, Marilyn and Couper, David J and Crenshaw, Anew and Dam, Rob and Doney, Alex and Dorkhan, Mozhgan and Edkins, Ted and Eriksson, Johan G and Esko, Tõnu and Eury, Elodie and Fadista, João and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul W and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Rebecca and Grant, George and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir and Hreidarsson, Astradur and Humphries, Steve E and Hunter, David J and Jackson, Anne and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 12/2015, Volume 47, Issue 12, pp. 1415 - 1425
Journal Article
by Gaulton, Kyle J and Ferreira, Teresa and Lee, Yeji and Raimondo, Anne and Mägi, Reedik and Reschen, Michael E and Mahajan, Anubha and Locke, Adam and William Rayner, N and Robertson, Neil and Scott, Robert A and Prokopenko, Inga and Scott, Laura J and Green, Todd and Sparso, Thomas and Thuillier, Dorothee and Yengo, Loic and Grallert, Harald and Wahl, Simone and Frånberg, Mattias and Strawbridge, Rona J and Kestler, Hans and Chheda, Himanshu and Eisele, Lewin and Gustafsson, Stefan and Steinthorsdottir, Valgerdur and Thorleifsson, Gudmar and Qi, Lu and Karssen, Lennart C and van Leeuwen, Elisabeth M and Willems, Sara M and Li, Man and Chen, Han and Fuchsberger, Christian and Kwan, Phoenix and Ma, Clement and Linderman, Michael and Lu, Yingchang and Thomsen, Soren K and Rundle, Jana K and Beer, Nicola L and van de Bunt, Martijn and Chalisey, Anil and Kang, Hyun Min and Voight, Benjamin F and Abecasis, Gonçalo R and Almgren, Peter and Baldassarre, Damiano and Balkau, Beverley and Benediktsson, Rafn and Blüher, Matthias and Boeing, Heiner and Bonnycastle, Lori L and Bottinger, Erwin P and Burtt, Noël P and Carey, Jason and Charpentier, Guillaume and Chines, Peter S and Cornelis, Marilyn C and Couper, David J and Crenshaw, Andrew T and van Dam, Rob M and Doney, Alex S F and Dorkhan, Mozhgan and Edkins, Sarah and Eriksson, Johan G and Esko, Tonu and Eury, Elodie and Fadista, Joao and Flannick, Jason and Fontanillas, Pierre and Fox, Caroline and Franks, Paul and Gertow, Karl and Gieger, Christian and Gigante, Bruna and Gottesman, Omri and Grant, George B and Grarup, Niels and Groves, Christopher J and Hassinen, Maija and Have, Christian T and Herder, Christian and Holmen, Oddgeir L and Hreidarsson, Astradur B and Humphries, Steve E and Hunter, David J and Jackson, Anne U and Jonsson, Anna and Jørgensen, Marit E and Jørgensen, Torben and Kao, Wen-Hong L and Kerrison, Nicola D and Kinnunen, Leena and Klopp, Norman and Kong, Augustine and Kovacs, Peter and Kraft, Peter and Kravic, Jasmina and Langford, Cordelia and ... and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Internal Medicine - Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and Department of History of Medicine and Lund University and Internmedicin - epidemiologi and Genetic and Molecular Epidemiology and Enheten för medicinens historia and EXODIAB: Excellence in Diabetes Research in Sweden
Nature Genetics, ISSN 1546-1718, 2015, Volume 47, Issue 12, p. 1415
We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
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