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1. Full Text Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence
by Lamas, Bruno and Michel, Marie-Laure and Waldschmitt, Nadine and Pham, Hang-Phuong and Zacharioudaki, Vassiliki and Dupraz, Louise and Delacre, Myriam and Natividad, Jane M and Costa, Gregory Da and Planchais, Julien and Sovran, Bruno and Bridonneau, Chantal and Six, Adrien and Langella, Philippe and Richard, Mathias L and Chamaillard, Mathias and Sokol, Harry
Gut, ISSN 0017-5749, 10/2018, Volume 67, Issue 10, pp. 1836 - 1844
germfree mice | microbiota | citrobacter rodentium | IBD | mono- and polysaccharides | pathogen-specific antibody | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Adaptive Immunity - physiology | Genetic Predisposition to Disease | Polysaccharides - adverse effects | Citrobacter rodentium - drug effects | Gastrointestinal Microbiome - physiology | Citrobacter rodentium - pathogenicity | Gene-Environment Interaction | CARD Signaling Adaptor Proteins - genetics | Host-Pathogen Interactions - immunology | Polysaccharides - metabolism | CARD Signaling Adaptor Proteins - metabolism | Animals | Colitis - microbiology | Immunity, Innate - physiology | Virulence - physiology | Diet Therapy - methods | Mice | Colitis - immunology | Competition | rRNA 16S | Virulence | Homeostasis | Hydrocarbons | Innate immunity | Infections | Genomes | Antibody response | Monosaccharides | Microbiota | Polysaccharides | E coli | Intestine | Rodents | Bacteria | Intestinal microflora | Food | Immune system | Pathogens | Immunoglobulins | Gnotobiotics | Bacterial infections | Cytokines | Lipocalin | Caspase | Inflammation | Adaptive immunity | Gene expression | Immune response (humoral) | Border patrol | Inflammatory bowel disease | Diet | Colitis | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Hépatology and Gastroenterology | Infectious diseases | Immunology
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2. Full Text The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure
by Waldschmitt, Nadine and Kitamoto, Sho and Secher, Thomas and Zacharioudaki, Vassiliki and Boulard, Olivier and Floquet, Emilie and Delacre, Myriam and Lamas, Bruno and Pham, Hang-Phuong and Six, Adrien and Richard, Mathias L and Dagorn, Jean-Charles and Eberl, Gérard and Langella, Philippe and Chatel, Jean-Marc and Ryffel, Bernhard and Iovanna, Juan Lucio and Poulin, Lionel F and Sokol, Harry and Kamada, Nobuhiko and Chamaillard, Mathias
Gut, ISSN 0017-5749, 07/2019, Volume 68, Issue 7, pp. 1190 - 1199
Colonic Microflora | Antibacterial Peptide | Interleukins | Macrophages | Barrier Function | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Phosphorylation | Transcription factors | rRNA 16S | Mucosa | Virulence | Infections | Kinases | Antibody response | Recruitment | Proteins | Microbiota | Cell activation | E coli | Intestine | Transcription activation | Bacteria | Feces | Nod1 protein | NOD2 protein | Community structure | Pathogens | NF-κB protein | Carbohydrates | Gnotobiotics | Cytokines | Threonine | Nucleotide sequence | Neutrophils | Pancreatitis | Inflammatory bowel disease | Lectins | Protein-serine/threonine kinase | Life Sciences | Immunology
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3. Full Text Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
by Pitt, Jonathan M and Vétizou, Marie and Daillère, Romain and Roberti, María Paula and Yamazaki, Takahiro and Routy, Bertrand and Lepage, Patricia and Boneca, Ivo Gomperts and Chamaillard, Mathias and Kroemer, Guido and Zitvogel, Laurence
Immunity (Cambridge, Mass.), ISSN 1074-7613, 06/2016, Volume 44, Issue 6, pp. 1255 - 1269
microbiota | immune-checkpoint blockade | immunotherapy | ipilimumab | PD-L1 | immunotherapy resistance | cancer | CTLA-4 | PD-1 | microbiome | Microbiota | Immunotherapy | Ipilimumab | Cancer | Immune-checkpoint blockade | Immunotherapy resistance | Microbiome | Life Sciences & Biomedicine | Immunology | Science & Technology | Immunotherapy - methods | Neoplasms - therapy | Tumor Escape | Animals | Neoplasms - immunology | Humans | Tumor Microenvironment | Antibodies, Monoclonal - therapeutic use | Drug Resistance, Neoplasm | Costimulatory and Inhibitory T-Cell Receptors - antagonists & inhibitors | Costimulatory and Inhibitory T-Cell Receptors - immunology | Molecular Targeted Therapy | Microbiota (Symbiotic organisms) | Antigens | Medical research | Melanoma | Cytotoxicity | T cell receptors | Metastasis | Cancer therapies | Success | Regulatory approval | Chemotherapy | Lymphocytes | Ligands | Regulation | Immune system | Tumors | Apoptosis | Index Medicus | Life Sciences
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4. Full Text NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
by Inohara, Naohiro and Chamaillard, Mathias and McDonald, Christine and Nuñez, Gabriel
Annual review of biochemistry, ISSN 0066-4154, 2005, Volume 74, Issue 1, pp. 355 - 383
Innate immunity | CARD15 | Crohn's disease | Nod2 | Nod proteins | Protein Structure, Tertiary | Inflammation - microbiology | Signal Transduction | Infection - immunology | Humans | Models, Molecular | Intracellular Signaling Peptides and Proteins - immunology | Infection - microbiology | Inflammation - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Nod2 Signaling Adaptor Protein | Infection - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Adaptor Proteins, Signal Transducing - immunology | Inflammation - genetics | Ligands | Nod1 Signaling Adaptor Protein | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Plants - immunology | Protein research | Genetic aspects | Research | Cytosol | Proteins | Genetics | Crohns disease | Immune system | Index Medicus
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5. Full Text The battlefield in the war against attaching-and-effacing bacterial pathogens: Monocytes, macrophages and dendritic cells in action
by Poulin, Lionel F and Chamaillard, Mathias
Veterinary microbiology, ISSN 0378-1135, 04/2017, Volume 202, pp. 47 - 51
Dendritic cell | Monocyte | Enteric bacterial infection | Macrophage | Veterinary Sciences | Life Sciences & Biomedicine | Microbiology | Science & Technology | Adaptive Immunity | Macrophages - physiology | Animals | Bacterial Adhesion - physiology | Humans | Dendritic Cells - physiology | Mononuclear Phagocyte System - physiology | Monocytes - physiology | Bacterial infections | Interleukins | Dendritic cells | Macrophages | Analysis | Nomenclature | Adjuvants | War | Vaccines | Veterinary medicine | Phagocytes | Monocytes | Bacteria | Mononuclear phagocyte system | Index Medicus
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6. Full Text Defining dysbiosis threatens Koch's postulates and current dogma on the role of Paneth cells in Crohn's disease
by Chamaillard, Mathias and Radulovic, Katarina
Gut, ISSN 0017-5749, 02/2016, Volume 65, Issue 2, pp. 190 - 191
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Intestines - microbiology | Dysbiosis - complications | Crohn Disease - etiology | Ileitis - etiology | Cell proliferation | Anti-infective agents | Care and treatment | Dosage and administration | Research | Dysbiosis | Studies | Researchers | Metabolism | Small intestine | Experiments | Crohns disease | Index Medicus | Abridged Index Medicus
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7. Full Text Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
by Marie Vétizou and Jonathan M. Pitt and Romain Daillère and Patricia Lepage and Nadine Waldschmitt and Caroline Flament and Sylvie Rusakiewicz and Bertrand Routy and Maria P. Roberti and Connie P. M. Duong and Vichnou Poirier-Colame and Antoine Roux and Sonia Becharef and Silvia Formenti and Encouse Golden and Sascha Cording and Gerard Eberl and Andreas Schlitzer and Florent Ginhoux and Sridhar Mani and Takahiro Yamazaki and Nicolas Jacquelot and David P. Enot and Marion Bérard and Jérôme Nigou and Paule Opolon and Alexander Eggermont and Paul-Louis Woerther and Elisabeth Chachaty and Nathalie Chaput and Caroline Robert and Christina Mateus and Guido Kroemer and Didier Raoult and Ivo Gomperts Boneca and Franck Carbonnel and Mathias Chamaillard and Laurence Zitvogel
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2015, Volume 350, Issue 6264, pp. 1079 - 1084
REPORTS | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Germ-Free Life - immunology | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Intestines - immunology | Dysbiosis - immunology | Immunotherapy | Aged, 80 and over | Adult | Female | Skin Neoplasms - therapy | Bacteroides - immunology | Mice, Inbred C57BL | CTLA-4 Antigen - immunology | Fecal Microbiota Transplantation | Animals | Gastrointestinal Microbiome - drug effects | Intestines - microbiology | Immunologic Memory | T-Lymphocytes - immunology | Aged | Anti-Bacterial Agents - pharmacology | Mice | Gastrointestinal Microbiome - immunology | CTLA-4 Antigen - antagonists & inhibitors | Melanoma - therapy | Usage | Cell receptors | Care and treatment | Microbiota (Symbiotic organisms) | Health aspects | Methods | Cancer | Stomach | Microbiology | Cells | Index Medicus | Microorganisms | Effectiveness | Antibodies | Patients | Tumors | Anticancer properties | Life Sciences
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8. Full Text NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer
by Couturier-Maillard, Aurélie and Secher, Thomas and Rehman, Ateequr and Normand, Sylvain and De Arcangelis, Adèle and Haesler, Robert and Huot, Ludovic and Grandjean, Teddy and Bressenot, Aude and Delanoye-Crespin, Anne and Gaillot, Olivier and Schreiber, Stefan and Lemoine, Yves and Ryffel, Bernhard and Hot, David and Nùñez, Gabriel and Chen, Grace and Rosenstiel, Philip and Chamaillard, Mathias
The Journal of clinical investigation, ISSN 0021-9738, 02/2013, Volume 123, Issue 2, pp. 700 - 711
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Nod2 Signaling Adaptor Protein - deficiency | Humans | Colitis - pathology | Male | Nod2 Signaling Adaptor Protein - genetics | Colorectal Neoplasms - etiology | Female | Colorectal Neoplasms - metabolism | Disease Models, Animal | Digestive System - metabolism | Risk Factors | Colorectal Neoplasms - microbiology | Mice, Knockout | Digestive System - pathology | Pregnancy | Colitis - etiology | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Colitis - microbiology | Colitis - metabolism | Mice | Receptor-Interacting Protein Serine-Threonine Kinases - deficiency | Colorectal Neoplasms - pathology | Metagenome | Digestive System - microbiology | Care and treatment | Microbiota (Symbiotic organisms) | Colorectal cancer | Physiological aspects | Genetic aspects | Research | Colitis | Risk factors | Index Medicus | Abridged Index Medicus | Receptor-Interacting Protein Serine-Threonine Kinases | Nod2 Signaling Adaptor Protein | Life Sciences | Immunology | Digestive System | Colorectal Neoplasms
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