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SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10383 - 16
Whole genome bisulfite sequencing (WGBS), with its ability to interrogate methylation status at single CpG site resolution epigenome-wide, is a powerful... 
DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | EPIGENOME-WIDE ASSOCIATION | DNA methylation | Bisulfite | Genomes | Methylation | Epidemiology | CpG islands
Journal Article
Molecular Metabolism, ISSN 2212-8778, 09/2019, Volume 27, pp. S33 - S41
Obesity and type 2 diabetes (T2D) are major public health issues worldwide, and put a significant burden on the healthcare system. Genetic variants, along with... 
Type 2 diabetes | Epigenetics | DNA methylation | Obesity | CIRCULATING MICRORNAS | CARBOHYDRATE RESPONSE ELEMENT | ADIPOSE-TISSUE HYPOXIA | PANCREATIC-ISLETS | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | BODY-MASS INDEX | EXPRESSION | EPIGENOME-WIDE ASSOCIATION | REVEALS
Journal Article
by Pereyra, Florencia and Jia, Xiaoming and McLaren, Paul J and Telenti, Amalio and de Bakker, Paul I. W and Walker, Bruce D and Ripke, Stephan and Brumme, Chanson J and Pulit, Sara L and Carrington, Mary and Kadie, Carl M and Carlson, Jonathan M and Heckerman, David and Graham, Robert R and Plenge, Robert M and Deeks, Steven G and Gianniny, Lauren and Crawford, Gabriel and Sullivan, Jordan and Gonzalez, Elena and Davies, Leela and Camargo, Amy and Moore, Jamie M and Beattie, Nicole and Gupta, Supriya and Crenshaw, Anew and Burtt, Noël P and Guiducci, Candace and Gupta, Namrata and Gao, Xiaojiang and Qi, Ying and Yuki, Yuko and Piechocka-Trocha, Alicja and Cutrell, Emily and Rosenberg, Rachel and Moss, Kristin L and Lemay, Paul and O'Leary, Jessica and Schaefer, Todd and Verma, Pranshu and Toth, Ildiko and Block, Brian and Baker, Brett and Rothchild, Alissa and Lian, Jeffrey and Proudfoot, Jacqueline and Alvino, Donna Marie L and Vine, Seanna and Addo, Marylyn M and Allen, Todd M and Altfeld, Marcus and Henn, Matthew R and Le Gall, Sylvie and Streeck, Henik and Haas, David W and Kuritzkes, Daniel R and Robbins, Gregory K and Shafer, Robert W and Gulick, Roy M and Shikuma, Cecilia M and Haubrich, Richard and Riddler, Sharon and Sax, Paul E and Daar, Eric S and Ribaudo, Heather J and Agan, Brian and Agarwal, Shanu and Ahern, Richard L and Allen, Brady L and Altidor, Sherly and Altschuler, Eric L and Ambardar, Sujata and Anastos, Kathryn and Anderson, Ben and Anderson, Val and Anady, Ushan and Antoniskis, Diana and Bangsberg, David and Barbaro, Daniel and Barrie, William and Bartczak, J and Barton, Simon and Basden, Patricia and Basgoz, Nesli and Bazner, Suzane and Bellos, Nicholaos C and Benson, Anne M and Berger, Judith and Bernard, Nicole F and Bernard, Annette M and Birch, Christopher and Bodner, Stanley J and Bolan, Robert K and Boueaux, Emilie T and Bradley, Meg and Braun, James F and Brndjar, Jon E and Brown, Stephen J and Brown, Katherine and Brown, Sheldon T and ... and Int HIV Controllers Study and International HIV Controllers Study and The International HIV Controllers Study
Science, ISSN 0036-8075, 12/2010, Volume 330, Issue 6010, pp. 1551 - 1557
Journal Article
by Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R and Torres, Jason M and Rayner, N. William and Payne, Anthony J and Steinthorsdottir, Valgerdur and Scott, Robert A and Grarup, Niels and Cook, James P and Schmidt, Ellen M and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael H and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F and Below, Jennifer E and Bowden, Donald W and Chambers, John Campbell and Kim, Young Jin and Ng, Maggie C. Y and Petty, Lauren E and Sim, Xueling and Zhang, Weihua and Bennett, Amanda J and Bork-Jensen, Jette and Brummett, Chad M and Canouil, Mickaël and Ec kardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon L. R and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E and Luan, Jian’an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C and Ford, Ian and Franco, Oscar H and Frayling, Timothy M and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T and Herder, Christian and Ikram, M. Arfan and Ingelsson, Martin and Jørgensen, Marit E and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L and Morris, Andrew D and Nadkarni, Girish and Pankow, James S and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R and Dupuis, Josée and Peyser, Patricia A and Zeggini, Eleftheria and Loos, Ruth J. F and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S and Jukema, J. Wouter and Palmer, Colin N. A and Grallert, Harald and Metspalu, Andres and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Geriatrik and Klinisk epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 11/2018, Volume 50, Issue 11, pp. 1505 - 1513
Journal Article
by Mahajan, Anubha and Wessel, Jennifer and Willems, Sara M and Zhao, Wei and Robertson, Neil R and Chu, Audrey Y and Gan, Wei and Kitajima, Hidetoshi and Taliun, Daniel and Rayner, N. William and Guo, Xiuqing and Lu, Yingchang and Li, Man and Jensen, Richard A and Hu, Yao and Huo, Shaofeng and Lohman, Kurt K and Zhang, Weihua and Cook, James P and Prins, Bram Peter and Flannick, Jason and Grarup, Niels and Trubetskoy, Vassily Vladimirovich and Kravic, Jasmina and Kim, Young Jin and Rybin, Denis V and Yaghootkar, Hanieh and Müller-Nurasyid, Martina and Meidtner, Karina and Li-Gao, Ruifang and Varga, Tibor V and Marten, Jonathan and Li, Jin and Smith, Albert Vernon and An, Ping and Ligthart, Symen and Gustafsson, Stefan and Malerba, Giovanni and Demirkan, Ayse and Tajes, Juan Fernandez and Steinthorsdottir, Valgerdur and Wuttke, Matthias and Lecoeur, Cécile and Preuss, Michael and Bielak, Lawrence F and Graff, Marielisa and Highland, Heather M and Justice, Anne E and Liu, Dajiang J and Marouli, Eirini and Peloso, Gina Marie and Warren, Helen R and Afaq, Saima and Afzal, Shoaib and Ahlqvist, Emma and Bang, Lia B and Bertoni, Alain G and Bombieri, Cristina and Bork-Jensen, Jette and Brandslund, Ivan and Brody, Jennifer A and Burtt, Noël P and Canouil, Mickaël and Chen, Yii-Der Ida and Cho, Yoon Shin and Christensen, Cramer and Eastwood, Sophie V and Eckardt, Kai-Uwe and Fischer, Krista and Gambaro, Giovanni and Giedraitis, Vilmantas and Grove, Megan L and De Haan, Hugoline G and Hackinger, Sophie and Hai, Yang and Han, Sohee and Tybjærg-Hansen, Anne and Hivert, Marie-France and Isomaa, Bo and Jäger, Susanne and Jørgensen, Marit E and Jørgensen, Torben and Käräjämäki, Annemari and Kim, Bong-Jo and Kim, Sung Soo and Koistinen, Heikki A and Kovacs, Peter and Kriebel, Jennifer and Kronenberg, Florian and Läll, Kristi and Lange, Leslie A and Lee, Jung-Jin and Lehne, Benjamin and Li, Huaixing and Lin, Keng-Hung and Linneberg, Allan and Liu, Ching-Ti and Liu, Jun and Loh, Marie and Mägi, Reedik and ... and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Genomics, Diabetes and Endocrinology and Diabetes - Islet Patophysiology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Genetisk och molekylär epidemiologi and Lunds universitet and Diabetes - Cardiovascular Disease and Lund University and Diabetes - öpatofysiologi and Genetic and Molecular Epidemiology
Nature Genetics, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 559 - 571
Journal Article
by Mahajan, A and Wessel, J and Willems, SM and Zhao, W and Robertson, NR and Chu, AY and Gan, W and Kitajima, H and Taliun, D and Rayner, NW and Guo, XQ and Lu, YC and Li, M and Jensen, RA and Hu, Y and Huo, SF and Lohman, KK and Zhang, WH and Cook, JP and Prins, BP and Flannick, J and Grarup, N and Trubetskoy, VV and Kravic, J and Kim, YJ and Rybin, DV and Yaghootkar, H and Muuller-Nurasyid, M and Meidtner, K and Li-Gao, RF and Varga, TV and Marten, J and Li, J and Smith, AV and An, P and Ligthart, S and Gustafsson, S and Malerba, G and Demirkan, A and Tajes, JF and Steinthorsdottir, V and Wuttke, M and Lecoeur, C and Preuss, M and Bielak, LF and Graff, M and Highland, HM and Justice, AE and Liu, DJ and Marouli, E and Peloso, GM and Warren, HR and Afaq, S and Afzal, S and Ahlqvist, E and Almgren, P and Amin, N and Bang, LB and Bertoni, AG and Bombieri, C and Bork-Jensen, J and Brandslund, I and Brody, JA and Burtt, NP and Canouil, M and Chen, YDI and Cho, YS and Christensen, C and Eastwood, SV and Eckardt, KU and Fischer, K and Gambaro, G and Giedraitis, V and Grove, ML and de Haan, HG and Hackinger, S and Hai, Y and Han, S and Tybjaerg-Hansen, A and Hivert, MF and Isomaa, B and Jager, S and Jorgensen, ME and Jorgensen, T and Karajamaki, A and Kim, BJ and Kim, SS and Koistinen, HA and Kovacs, P and Kriebel, J and Kronenberg, F and Lall, K and Lange, LA and Lee, JJ and Lehne, B and Li, HX and Lin, KH and Linneberg, A and Liu, CT and Liu, J and ... and MAGIC Consortium and ExomeBP Consortium and GIANT Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet
NATURE GENETICS, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 559 - 559
Journal Article
Theory & Psychology, ISSN 0959-3543, 10/2008, Volume 18, Issue 5, p. 675
  Drawing on Bickhard's interactivism along with philosophical hermeneutics, we outline a plausible ontology of human action and development that might serve... 
Exegesis & hermeneutics | Happiness | Theory | Psychology | Behavior | Philosophy
Journal Article
by Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R and Torres, Jason M and Rayner, N William and Payne, Anthony J and Steinthorsdottir, Valgerdur and Scott, Robert A and Grarup, Niels and Cook, James P and Schmidt, Ellen M and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael H and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F and Below, Jennifer E and Bowden, Donald W and Chambers, John Campbell and Kim, Young Jin and Ng, Maggie CY and Petty, Lauren E and Sim, Xueling and Zhang, Weihua and Bennett, Amanda J and Bork-Jensen, Jette and Brummett, Chad M and Canouil, Mickaël and Ec Kardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon LR and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E and Luan, Jian'an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C and Ford, Ian and Franco, Oscar H and Frayling, Timothy M and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T and Herder, Christian and Ikram, M Arfan and Ingelsson, Martin and Jørgensen, Marit E and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L and Morris, Andrew D and Nadkarni, Girish and Pankow, James S and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R and Dupuis, Josée and Peyser, Patricia A and Zeggini, Eleftheria and Loos, Ruth JF and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S and Jukema, J Wouter and Palmer, Colin NA and Grallert, Harald and Metspalu, Andres and ...
ISSN 1061-4036, 2018
We aggregated genome-wide genotyping data from 32 European-descent GWAS (74,124 T2D cases, 824,006 controls) imputed to high-density reference panels of... 
Journal Article
by Mahajan, Anubha and Wessel, Jennifer and Willems, Sara M and Zhao, Wei and Robertson, Neil R and Chu, Audrey Y and Gan, Wei and Kitajima, Hidetoshi and Taliun, Daniel and Rayner, N William and Guo, Xiuqing and Lu, Yingchang and Li, Man and Jensen, Richard A and Hu, Yao and Huo, Shaofeng and Lohman, Kurt K and Zhang, Weihua and Cook, James P and Prins, Bram Peter and Flannick, Jason and Grarup, Niels and Trubetskoy, Vassily Vladimirovich and Kravic, Jasmina and Kim, Young Jin and Rybin, Denis V and Yaghootkar, Hanieh and Müller-Nurasyid, Martina and Meidtner, Karina and Li-Gao, Ruifang and Varga, Tibor V and Marten, Jonathan and Li, Jin and Smith, Albert Vernon and An, Ping and Ligthart, Symen and Gustafsson, Stefan and Malerba, Giovanni and Demirkan, Ayse and Tajes, Juan Fernandez and Steinthorsdottir, Valgerdur and Wuttke, Matthias and Lecoeur, Cécile and Preuss, Michael and Bielak, Lawrence F and Graff, Marielisa and Highland, Heather M and Justice, Anne E and Liu, Dajiang J and Marouli, Eirini and Peloso, Gina Marie and Warren, Helen R and ExomeBP Consortium and MAGIC Consortium and GIANT Consortium and Afaq, Saima and Afzal, Shoaib and Ahlqvist, Emma and Almgren, Peter and Amin, Najaf and Bang, Lia B and Bertoni, Alain G and Bombieri, Cristina and Bork-Jensen, Jette and Brandslund, Ivan and Brody, Jennifer A and Burtt, Noël P and Canouil, Mickaël and Chen, Yii-Der Ida and Cho, Yoon Shin and Christensen, Cramer and Eastwood, Sophie V and Eckardt, Kai-Uwe and Fischer, Krista and Gambaro, Giovanni and Giedraitis, Vilmantas and Grove, Megan L and de Haan, Hugoline G and Hackinger, Sophie and Hai, Yang and Han, Sohee and Tybjærg-Hansen, Anne and Hivert, Marie-France and Isomaa, Bo and Jäger, Susanne and Jørgensen, Marit E and Jørgensen, Torben and Käräjämäki, Annemari and Kim, Bong-Jo and Kim, Sung Soo and Koistinen, Heikki A and Kovacs, Peter and Kriebel, Jennifer and Kronenberg, Florian and Läll, Kristi and Lange, Leslie A and Lee, Jung-Jin and Lehne, Benjamin and Li, Huaixing and Lin, Keng-Hung and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Geriatrik and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 2018, Volume 50, Issue 4, p. 559
Identification of coding variant associations for complex diseases offers a direct route to biological insight, but is dependent on appropriate inference... 
ExomeBP Consortium | MAGIC Consortium | GIANT Consortium | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
by Anubha Mahajan and Jennifer Wessel and Sara M Willems and Wei Zhao and Neil R Robertson and Audrey Y Chu and Wei Gan and Hidetoshi Kitajima and Daniel Taliun and N William Rayner and Xiuqing Guo and Yingchang Lu and Man Li and Richard A Jensen and Yao Hu and Shaofeng Huo and Kurt K Lohman and Weihua Zhang and James P Cook and Bram Peter Prins and Jason Flannick and Niels Grarup and Vassily Vladimirovich Trubetskoy and Jasmina Kravic and Young Jin Kim and Denis V Rybin and Hanieh Yaghootkar and Martina Müller-Nurasyid and Karina Meidtner and Ruifang Li-Gao and Tibor V Varga and Jonathan Marten and Jin Li and Albert Vernon Smith and Ping An and Symen Ligthart and Stefan Gustafsson and Giovanni Malerba and Ayse Demirkan and Juan Fernandez Tajes and Valgerdur Steinthorsdottir and Matthias Wuttke and Cécile Lecoeur and Michael Preuss and Lawrence F Bielak and Marielisa Graff and Heather M Highland and Anne E Justice and Dajiang J Liu and Eirini Marouli and Gina Marie Peloso and Helen R Warren and Saima Afaq and Shoaib Afzal and Emma Ahlqvist and Peter Almgren and Najaf Amin and Lia B Bang and Alain G Bertoni and Cristina Bombieri and Jette Bork-Jensen and Ivan Brandslund and Jennifer A Brody and Noël P Burtt and Mickaël Canouil and Yii-Der Ida Chen and Yoon Shin Cho and Cramer Christensen and Sophie V Eastwood and Kai-Uwe Eckardt and Krista Fischer and Giovanni Gambaro and Vilmantas Giedraitis and Megan L Grove and Hugoline G de Haan and Sophie Hackinger and Yang Hai and Sohee Han and Anne Tybjæ rg-Hansen and Marie-France Hivert and Bo Isomaa and Susanne Jäger and Marit E Jørgensen and Torben Jørgensen and Annemari Käräjämäki and Bong-Jo Kim and Sung Soo Kim and Heikki A Koistinen and Peter Kovacs and Jennifer Kriebel and Florian Kronenberg and Kristi Läll and Leslie A Lange and Jung-Jin Lee and Benjamin Lehne and Huaixing Li and Keng-Hung Lin and Allan Linneberg and Ching-Ti Liu and Jun Liu and ...
Nature Genetics, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 559 - 3
We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls of diverse ancestry, identifying 40 coding variant association signals... 
Haplotypes | Target recognition | Therapeutic applications | Diabetes mellitus | Genomics | Inference | Identification | Genomes | Epidemiology | Studies | Body mass index | Genotype & phenotype | Quality control | Diabetes | Diabetes mellitus (non-insulin dependent)
Journal Article