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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2017, Volume 114, Issue 5, pp. E761 - E770
Although immunotherapy by PD-1 blockade has dramatically improved the survival rate of cancer patients, further improvement in efficacy is required to reduce... 
Mitochondria | PGC-1α | Immune metabolism | Cancer immunotherapy | PD-1 | PGC-1 alpha | mitochondria | MULTIDISCIPLINARY SCIENCES | CANCER-IMMUNOTHERAPY | DILATED CARDIOMYOPATHY | PROTEIN-SYNTHESIS | EFFECTOR | RESPONSES | MEMORY | IMMUNE CHECKPOINT BLOCKADE | ENERGY HOMEOSTASIS | cancer immunotherapy | immune metabolism | TUMOR MICROENVIRONMENT | PD-1-DEFICIENT MICE | Neoplasms - metabolism | Thiophenes - therapeutic use | AMP-Activated Protein Kinases - metabolism | Reactive Oxygen Species - metabolism | TOR Serine-Threonine Kinases - metabolism | Triazines - therapeutic use | Antibodies, Monoclonal - therapeutic use | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Pyrones - pharmacology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Morpholines - therapeutic use | Cytokines - immunology | T-Lymphocytes, Cytotoxic - immunology | Triazines - pharmacology | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Oxygen Consumption | Morpholines - pharmacology | Programmed Cell Death 1 Receptor - metabolism | Thiophenes - pharmacology | Mitochondria - metabolism | Lymph Nodes - immunology | Mitochondria - drug effects | Mice, Knockout | Neoplasms - drug therapy | Animals | T-Lymphocytes, Cytotoxic - metabolism | Neoplasms - immunology | Cell Line, Tumor | Pyrones - therapeutic use | Mice, Inbred BALB C | Programmed Cell Death 1 Receptor - immunology | Programmed Cell Death 1 Receptor - genetics | Care and treatment | T cells | Health aspects | Immunotherapy | Methods | Cancer | Oxygen | Adipocytes | Kinases | Chemicals | Tumors | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
[Rinsho ketsueki] The Japanese journal of clinical hematology, ISSN 0485-1439, 01/2016, Volume 57, Issue 10, pp. 2224 - 2231
Journal Article
Current topics in microbiology and immunology, ISSN 0070-217X, 01/2017, Volume 410, p. E1
Journal Article
European Journal of Immunology, ISSN 0014-2980, 07/2010, Volume 40, Issue 7, pp. 1927 - 1937
Journal Article
[Rinsho ketsueki] The Japanese journal of clinical hematology, ISSN 0485-1439, 2016, Volume 57, Issue 10, p. 2224
Immune checkpoint inhibitors, especially anti-programmed cell death-1 (PD-1) antibodies, have revolutionized cancer therapy. A PD-1 antibody, nivolumab, was... 
Biomarkers, Tumor - blood | Neoplasms - therapy | Animals | Prognosis | Neoplasms - immunology | Humans | Immunotherapy | Clinical Trials as Topic | Neoplasms - diagnosis | Programmed Cell Death 1 Receptor - immunology | Molecular Targeted Therapy
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2017, Volume 18, Issue 12, pp. 1342 - 1352
Journal Article
Current Topics in Microbiology and Immunology, ISSN 0070-217X, 2017, Volume 410, pp. 75 - 97
Immunity developed to defend our bodies from foreign particles, including bacteria and viruses. Although effector cells responsible for acquired immunity,... 
PDCD1 GENE | POSITIVE SELECTION | ONCOLOGY | T-CELL-ACTIVATION | PROGRAMMED DEATH-1 PD-1 | INHIBITORY RECEPTOR PD-1 | B7 FAMILY | REGULATORY POLYMORPHISM | IMMUNOLOGY | UP-REGULATION | CLINICAL-SIGNIFICANCE | CHECKPOINT BLOCKADE | Programmed Cell Death 1 Receptor | B7-H1 Antigen | Immunity | Humans | Immunotherapy
Journal Article
Nature Communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, pp. 15244 - 15244
Classical antigen processing leads to the presentation of antigenic peptides derived from endogenous and exogenous sources for MHC class I and class II... 
MHC CLASS-I | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | CHRONIC BERYLLIUM DISEASE | ENDOPLASMIC-RETICULUM | BINDING | EXPRESSION | T-CELLS | GREEN FLUORESCENT PROTEINS | INVARIANT CHAIN COMPLEXES | MOLECULES | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, pp. e0156114 - e0156114
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 9
Current clinically approved biomarkers for the PD-1 blockade cancer immunotherapy are based entirely on the properties of tumour cells. With increasing... 
FORM | MULTIDISCIPLINARY SCIENCES | CD28 | COSTIMULATION | ANTITUMOR IMMUNITY | CELL | MOLECULES | ELISA | Automation | CTLA-4 protein | Immune checkpoint | PD-1 protein | Immunotherapy | PD-L1 protein | Biomarkers | Immune status | Tumors
Journal Article
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 05/2017, Volume 198, Issue 9, pp. 3757 - 3757
Journal Article
EUROPEAN JOURNAL OF IMMUNOLOGY, ISSN 0014-2980, 07/2010, Volume 40, Issue 7, pp. 1927 - 1937
Based on the evidence that IL-17 is a key cytokine involved in various inflammatory diseases, we explored the critical role of IL-17-producing gamma delta T... 
CUTANEOUS CARCINOGENESIS | Tumor microenvironment | IFN-GAMMA | OVARIAN-CANCER | IMMUNOLOGY | gamma delta T cell | IMMUNE-SYSTEM | INTERFERON-GAMMA | MICROENVIRONMENT | SIGNALING PATHWAY | INFLAMMATION | IL-17 | IN-VIVO | GROWTH
Journal Article
Journal Article