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1. Full Text EBV‐encoded miRNAs target ATM‐mediated response in nasopharyngeal carcinoma
by Lung, Raymond W‐M and Hau, Pok‐Man and Yu, Ken H‐O and Yip, Kevin Y and Tong, Joanna H‐M and Chak, Wing‐Po and Chan, Anthony W‐H and Lam, Ka‐Hei and Lo, Angela Kwok‐Fung and Tin, Edith K‐Y and Chau, Shuk‐Ling and Pang, Jesse C‐S and Kwan, Johnny S‐H and Busson, Pierre and Young, Lawrence S and Yap, Lee‐Fah and Tsao, Sai‐Wah and To, Ka‐Fai and Lo, Kwok‐Wai
The Journal of pathology, ISSN 0022-3417, 04/2018, Volume 244, Issue 4, pp. 394 - 407
nasopharyngeal carcinoma | ATM serine/threonine kinase (ATM) | transcriptome sequencing | Epstein–Barr virus | EBV‐miRNAs | EBV-miRNAs | Pathology | Oncology | Life Sciences & Biomedicine | Science & Technology | Nasopharyngeal Neoplasms - genetics | Herpesvirus 4, Human - genetics | Virus Latency | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Nasopharyngeal Neoplasms - virology | Transcriptome | Male | Nasopharyngeal Neoplasms - pathology | Nasopharyngeal Carcinoma - enzymology | Nasopharyngeal Carcinoma - virology | Heterografts | RNA, Viral - genetics | Ataxia Telangiectasia Mutated Proteins - biosynthesis | Female | 3' Untranslated Regions | Binding Sites | Epstein-Barr Virus Infections - virology | Nasopharyngeal Neoplasms - enzymology | Host-Pathogen Interactions | Animals | Nasopharyngeal Carcinoma - genetics | Mice, Nude | Nasopharyngeal Carcinoma - pathology | Cell Line, Tumor | Epstein-Barr Virus Infections - diagnosis | MicroRNAs - genetics | DNA Damage | Ataxia Telangiectasia Mutated Proteins - genetics | Enzyme Repression | Carcinoma | MicroRNA | Analysis | Cancer | Transcription | Xenotransplantation | DNA damage | Viruses | Activation | Malignancy | Tissues | Gene sequencing | Nasopharyngeal carcinoma | Signal transduction | Transfection | Xenografts | Ataxia | miRNA | Tumorigenesis | Deoxyribonucleic acid--DNA | Tumor cells | Invasiveness | Double-strand break repair | Gene expression | Ribonucleic acid--RNA | Latency | Signaling | 3' Untranslated regions | Ataxia telangiectasia mutated protein | Tumors | Index Medicus | threonine kinase (ATM) | Original Papers | Original Paper | ATM serine
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2. Full Text Guideline-Based Critical Care Pathway Improves Long-Term Clinical Outcomes in Patients with Acute Coronary Syndrome
by Hai, Jo-Jo and Wong, Chun-Ka and Un, Ka-Chun and Wong, Ka-Lam and Zhang, Zhe-Yu and Chan, Pak-Hei and Lam, Yui-Ming and Chan, Wing-Sze and Lam, Cheung-Chi and Tam, Chor-Cheung and Wong, Yiu-Tung and Yung, See-Yue and Chan, Ki-Wan and Siu, Chung-Wah and Lau, Chu-Pak and Tse, Hung-Fat
Scientific reports, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 16814 - 9
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Compliance | Mortality | Critical care | Acute coronary syndromes | Survival | Patients | Clinical outcomes | Index Medicus
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3. Full Text Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians
by Yang, Wanling and Tang, Huayang and Zhang, Yan and Tang, Xianfa and Zhang, Jing and Sun, Liangdan and Yang, Jing and Cui, Yong and Zhang, Lu and Hirankarn, Nattiya and Cheng, Hui and Pan, Hai-Feng and Gao, Jinping and Lee, Tsz Leung and Sheng, Yujun and Lau, Chak Sing and Li, Yang and Chan, Tak Mao and Yin, Xianyong and Ying, Dingge and Lu, Qianjin and Leung, Alexander Moon Ho and Zuo, Xianbo and Chen, Xiang and Tong, Kwok Lung and Zhou, Fusheng and Diao, Qingchun and Tse, Niko Kei Chiu and Xie, Hongfu and Mok, Chi Chiu and Hao, Fei and Wong, Sik Nin and Shi, Bingjun and Lee, Ka Wing and Hui, Yan and Ho, Marco Hok Kung and Liang, Bo and Lee, Pamela Pui Wah and Cui, Hongzhou and Guo, Qing and Chung, Brian Hon-Yin and Pu, Xiongming and Liu, Qiji and Zhang, Xiaoguang and Zhang, Change and Chong, Chun Yin and Fang, Hong and Wong, Raymond Woon Sing and Sun, Yonghu and Mok, Mo Yin and Li, Xiang-Pei and Avihingsanon, Yingyos and Zhai, Zhifang and Rianthavorn, Pornpimol and Deekajorndej, Thavatchai and Suphapeetiporn, Kanya and Gao, Fei and Shotelersuk, Vorasuk and Kang, Xiaojing and Ying, Shirley King Yee and Zhang, Lijuan and Wong, Wilfred Hing Sang and Zhu, Dingxian and Fung, Samuel Ka Shun and Zeng, Fanqin and Lai, Wai Ming and Wong, Chun-Ming and Ng, Irene Oi Lin and Garcia-Barceló, Maria-Mercè and Cherny, Stacey S and Shen, Nan and Tam, Paul Kwong-Hang and Sham, Pak Chung and Ye, Dong-Qing and Yang, Sen and Zhang, Xuejun and Lau, Yu Lung
American journal of human genetics, ISSN 0002-9297, 01/2013, Volume 92, Issue 1, pp. 41 - 51
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | B7-1 Antigen - genetics | Humans | Asian Continental Ancestry Group - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Membrane Proteins | Proteins - genetics | Dioxygenases - genetics | Lupus Erythematosus, Systemic - ethnology | Lupus Erythematosus, Systemic - genetics | Polymorphism, Single Nucleotide | Cyclin-Dependent Kinase Inhibitor p27 - genetics | DNA replication | Systemic lupus erythematosus | Genetic susceptibility | Causes of | Genetic aspects | Heritability | Research | Human population genetics | Asians | Diseases | Lupus | Analysis | Pathogenesis | Genetics | Gene loci | Cultural differences | Meta-analysis | Index Medicus
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4. Full Text Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009
by Pai, Sung-Yun and Logan, Brent R and Griffith, Linda M and Buckley, Rebecca H and Parrott, Roberta E and Dvorak, Christopher C and Kapoor, Neena and Hanson, Imelda C and Filipovich, Alexandra H and Jyonouchi, Soma and Sullivan, Kathleen E and Small, Trudy N and Burroughs, Lauri and Skoda-Smith, Suzanne and Haight, Ann E and Grizzle, Audrey and Pulsipher, Michael A and Chan, Ka Wah and Fuleihan, Ramsay L and Haddad, Elie and Loechelt, Brett and Aquino, Victor M and Gillio, Alfred and Davis, Jeffrey and Knutsen, Alan and Smith, Angela R and Moore, Theodore B and Schroeder, Marlis L and Goldman, Frederick D and Connelly, James A and Porteus, Matthew H and Xiang, Qun and Shearer, William T and Fleisher, Thomas A and Kohn, Donald B and Puck, Jennifer M and Notarangelo, Luigi D and Cowan, Morton J and O'Reilly, Richard J
The New England journal of medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 5, pp. 434 - 446
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Graft vs Host Disease - epidemiology | Humans | Severe Combined Immunodeficiency - mortality | Severe Combined Immunodeficiency - therapy | Infant | Male | Survival Rate | Treatment Outcome | Severe Combined Immunodeficiency - immunology | Hematopoietic Stem Cell Transplantation - mortality | Incidence | Retreatment | CD3 Complex - blood | Hematopoietic Stem Cell Transplantation - adverse effects | Immunoglobulin A - blood | Lymphocyte Count | Female | T-Lymphocytes - immunology | Retrospective Studies | Transplantation Conditioning | Siblings | Transplantation of organs, tissues, etc | Research | Health aspects | Patient outcomes | Reorganization and restructuring | Immunodeficiency | Cell proliferation | Cell survival | Severe combined immunodeficiency | Transplants & implants | Hypersensitivity | Infections | Infants | Lymphocytes T | Transplantation | CD3 antigen | Immunoglobulin A | Hemopoiesis | CD4 antigen | Infectious diseases | Donors | Stem cells | Bone marrow | Children | Immune system | Index Medicus | Abridged Index Medicus
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5. Full Text Exome and genome sequencing of nasopharynx cancer identifies NF-? B pathway activating mutations
by Li, Yvonne Y and Chung, Grace T.Y and Lui, Vivian W.Y and To, Ka-Fai and Ma, Brigette B.Y and Chow, Chit and Woo, John K.S and Yip, Kevin Y and Seo, Jeongsun and Hui, Edwin P and Mak, Michael K.F and Rusan, Maria and Chau, Nicole G and Or, Yvonne Y.Y and Law, Marcus H.N and Law, Peggy P.Y and Liu, Zoey W.Y and Ngan, Hoi-Lam and Hau, Pok-Man and Verhoeft, Krista R and Poon, Peony H.Y and Yoo, Seong-Keun and Shin, Jong-Yeon and Lee, Sau-Dan and Lun, Samantha W.M and Jia, Lin and Chan, Anthony W.H and Chan, Jason Y.K and Lai, Paul B.S and Fung, Choi-Yi and Hung, Suet-Ting and Wang, Lin and Chang, Ann Margaret V and Chiosea, Simion I and Hedberg, Matthew L and Tsao, Sai-Wah and Van Hasselt, Andrew C and Chan, Anthony T.C and Grandis, Jennifer R and Hammerman, Peter S and Lo, Kwok-Wai
Nature communications, 01/2017, Volume 8, p. 14121
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6. Full Text Specific targeting of point mutations in EGFR L858R-positive lung cancer by CRISPR/Cas9
by Cheung, Alvin Ho-Kwan and Chow, Chit and Zhang, Jinglin and Zhou, Yuhang and Huang, Tingting and Ng, Kayla Ching-Kei and Or, Terry Cho-Tsun and Yao, Yoyo Yao and Dong, Yujuan and Fung, Jackie Mei-Wah and Xiong, Lei and Chan, Aden Ka-Yin and Lung, Wai-Ming Raymond and Kang, Wei and To, Ka-Fai
Laboratory investigation, ISSN 0023-6837, 07/2018, Volume 98, Issue 7, pp. 968 - 976
Pathology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Lung Neoplasms - genetics | Point Mutation - genetics | DNA Mutational Analysis | Humans | ErbB Receptors - genetics | Cell Line, Tumor | Lung Neoplasms - therapy | CRISPR-Cas Systems - genetics | DNA Cleavage | Genetic Therapy - methods | Cell proliferation | CRISPR | Epidermal growth factor receptors | Nucleotide sequence | Lung cancer | Genomes | Gene sequencing | Proteins | Point mutation | Strategy | Cleavage | Mutation | Endonuclease | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
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7. Full Text Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures
by Hui, Kenrie P Y and Cheung, Man-Chun and Perera, Ranawaka A P M and Ng, Ka-Chun and Bui, Christine H T and Ho, John C W and Ng, Mandy M T and Kuok, Denise I T and Shih, Kendrick C and Tsao, Sai-Wah and Poon, Leo L M and Peiris, Malik and Nicholls, John M and Chan, Michael C W
The lancet respiratory medicine, ISSN 2213-2600, 07/2020, Volume 8, Issue 7, pp. 687 - 695
Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Pandemics | Humans | Middle Aged | Coronavirus Infections - physiopathology | Male | Respiratory Mucosa - virology | Betacoronavirus - immunology | COVID-19 | Respiratory System - virology | SARS-CoV-2 | Betacoronavirus - physiology | Respiratory Mucosa - immunology | Aged, 80 and over | Adult | Female | Respiratory Mucosa - physiopathology | Respiratory System - immunology | Viral Tropism - physiology | Conjunctiva - immunology | Conjunctiva - physiopathology | Conjunctiva - virology | Coronavirus Infections - immunology | Pneumonia, Viral - immunology | Pneumonia, Viral - physiopathology | Immunity, Innate - immunology | Respiratory System - physiopathology | Aged | Virus Replication - physiology | Index Medicus
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8. Full Text Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial
by Hung, Ivan Fan-Ngai and Lung, Kwok-Cheung and Tso, Eugene Yuk-Keung and Liu, Raymond and Chung, Tom Wai-Hin and Chu, Man-Yee and Ng, Yuk-Yung and Lo, Jenny and Chan, Jacky and Tam, Anthony Raymond and Shum, Hoi-Ping and Chan, Veronica and Wu, Alan Ka-Lun and Sin, Kit-Man and Leung, Wai-Shing and Law, Wai-Lam and Lung, David Christopher and Sin, Simon and Yeung, Pauline and Yip, Cyril Chik-Yan and Zhang, Ricky Ruiqi and Fung, Agnes Yim-Fong and Yan, Erica Yuen-Wing and Leung, Kit-Hang and Ip, Jonathan Daniel and Chu, Allen Wing-Ho and Chan, Wan-Mui and Ng, Anthony Chin-Ki and Lee, Rodney and Fung, Kitty and Yeung, Alwin and Wu, Tak-Chiu and Chan, Johnny Wai-Man and Yan, Wing-Wah and Chan, Wai-Ming and Chan, Jasper Fuk-Woo and Lie, Albert Kwok-Wai and Tsang, Owen Tak-Yin and Cheng, Vincent Chi-Chung and Que, Tak-Lun and Lau, Chak-Sing and Chan, Kwok-Hung and To, Kelvin Kai-Wang and Yuen, Kwok-Yung
The Lancet (British edition), ISSN 0140-6736, 05/2020, Volume 395, Issue 10238, pp. 1695 - 1704
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antiviral agents | Product development | Biological response modifiers | Lopinavir | Viral antigens | Interferon beta | Therapy | Pandemics | Laboratories | Ritonavir | Health services | Viral diseases | Population studies | Infections | Middle East respiratory syndrome | Ribavirin | COVID-19 | Hepatitis | Randomization | Drug dosages | Signs and symptoms | Bacterial infections | Cytokines | Severe acute respiratory syndrome | Diarrhea | Nausea | Coronaviruses | Patients | Severe acute respiratory syndrome coronavirus 2 | Polymerase chain reaction | Influenza | Respiratory diseases | Interferon | Mutation | Index Medicus | Abridged Index Medicus
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