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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2018, Volume 115, Issue 35, p. E8286
Unrestrained 53BP1 activity at DNA double-strand breaks (DSBs) hampers DNA end resection and upsets DSB repair pathway choice. RNF169 acts as a molecular... 
Annealing | Cloning | DNA damage | Genetics | Homology | Genetic engineering | Double-strand break repair | Repair | Deoxyribonucleic acid--DNA | Deposition
Journal Article
Current Pharmacology Reports, ISSN 2198-641X, 8/2018, Volume 4, Issue 4, pp. 292 - 300
Histone modifications are one form of epigenetic information that relate closely to gene regulation. Aberrant histone methylation caused by alteration in... 
Biomedicine, general | Biomedicine | H3K36M | H3K27M | Cancer Research | Molecular Medicine | Pharmacology/Toxicology | Histone mutations | Cancer | Epigenetics (ATY Lau, Section Editor)
Journal Article
ISSN 0027-8424, 2018
Unrestrained 53BP1 activity at DNA double-strand breaks (DSBs) hampers DNA end resection and upsets DSB repair pathway choice. RNF169 acts as a molecular... 
DNA--Research | Molecular biology | DNA--Synthesis | Mobile genetic elements
Journal Article
by Stunnenberg, Hendrik G and Abrignani, Sergio and Adams, David and de Almeida, Melanie and Altucci, Lucia and Amin, Viren and Amit, Ido and Antonarakis, Stylianos E and Aparicio, Samuel and Arima, Takahiro and Arrigoni, Laura and Arts, Rob and Asnafi, Vahid and Esteller, Manel and Bae, Jae-Bum and Bassler, Kevin and Beck, Stephan and Berkman, Benjamin and Bernstein, Bradley E and Bilenky, Mikhail and Bird, Adrian and Bock, Christoph and Boehm, Bernhard and Bourque, Guillaume and Breeze, Charles E and Brors, Benedikt and Bujold, David and Burren, Oliver and Bussemakers, Marion J and Butterworth, Adam and Campo, Elias and Carrillo-de-Santa-Pau, Enrique and Chadwick, Lisa and Chan, Kui Ming and Chen, Wei and Cheung, Tom H and Chiapperino, Luca and Choi, Nak Hyen and Chung, Ho-Ryun and Clarke, Laura and Connors, Joseph M and Cronet, Philippe and Danesh, John and Dermitzakis, Manolis and Drewes, Gerard and Durek, Pawel and Dyke, Stephanie and Dylag, Tomasz and Eaves, Connie J and Ebert, Peter and Eils, Roland and Eils, Jürgen and Ennis, Catherine A and Enver, Tariq and Feingold, Elise A and Felder, Bärbel and Ferguson-Smith, Anne and Fitzgibbon, Jude and Flicek, Paul and Foo, Roger S.-Y and Fraser, Peter and Frontini, Mattia and Furlong, Eileen and Gakkhar, Sitanshu and Gasparoni, Gilles and Gasparoni, Nina and Geschwind, Daniel H and Glažar, Petar and Graf, Thomas and Grosveld, Frank and Guan, Xin-Yuan and Guigo, Roderic and Gut, Ivo G and Hamann, Alf and Han, Bok-Ghee and Harris, R. Alan and Heath, Simon and Helin, Kristian and Hengstler, Jan G and Heravi-Moussavi, Alireza and Herrup, Karl and Hill, Steven and Hilton, Jason A and Hitz, Benjamin C and Horsthemke, Bernhard and Hu, Ming and Hwang, Joo-Yeon and Ip, Nancy Y and Ito, Takashi and Javierre, Biola-Maria and Jenko, Sasa and Jenuwein, Thomas and Joly, Yann and Jones, Steven J.M and Kanai, Yae and Kang, Hee Gyung and Karsan, Aly and Kiemer, Alexandra K and Kim, Song Cheol and Kim, Hyeon-Hoe and ... and Int Human Epigenome Consortium and International Human Epigenome Consortium
Cell, ISSN 0092-8674, 11/2016, Volume 167, Issue 5, pp. 1145 - 1149
The International Human Epigenome Consortium (IHEC) coordinates the generation of a catalog of high-resolution reference epigenomes of major primary human cell... 
LINKS | VARIANTS | REVEAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | EPIGENETIC STATE | CELL BIOLOGY | DNA Methylation | Epigenomics | Disease - genetics | Epigenesis, Genetic | Humans | Databases, Genetic | Histone Code | Genome, Human | Epigenetic inheritance | Cells | Web portals | Epigenetics | ADN | Human genome | DNA | Genoma humà | Epigenètica
Journal Article
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2005, Volume 11, Issue 7, pp. 780 - 785
Premature aging syndromes often result from mutations in nuclear proteins involved in the maintenance of genomic integrity. Lamin A is a major component of the... 
MEDICINE, RESEARCH & EXPERIMENTAL | RECOMBINATION | LAMIN-A | METALLOPROTEINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | DOUBLE-STRAND BREAKS | HUTCHINSON-GILFORD PROGERIA | MICE | CELLULAR SENESCENCE | ZMPSTE24 | CELL BIOLOGY | Metalloendopeptidases - genetics | Gamma Rays | Genomic Instability | Humans | DNA Repair - physiology | Bone Marrow Cells - physiology | Metalloendopeptidases - metabolism | Aging, Premature - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Histones - radiation effects | Mice, Mutant Strains | DNA Damage - genetics | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Cellular Senescence - genetics | Protein Precursors - genetics | Rad51 Recombinase | Membrane Proteins - genetics | Chromosomal Proteins, Non-Histone | Nuclear Proteins - metabolism | Bone Marrow Cells - radiation effects | Lamin Type A - metabolism | Phosphoproteins - genetics | DNA-Binding Proteins - genetics | Fibroblasts - pathology | Protein Precursors - metabolism | DNA - genetics | Animals | Histones - genetics | Fibroblasts - radiation effects | Chromosome Aberrations | Lamin Type A - genetics | Mice | Histones - metabolism | Tumor Suppressor p53-Binding Protein 1
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 10/2011, Volume 108, Issue 40, pp. 16699 - 16704
X chromosome inactivation (XCI) is the most dramatic example of epigenetic silencing in eukaryotes. Once established, the inactivated X chromosome (Xi) remains... 
Gene silencing | RNA-mediated interference | X chromosome | Cell division | Heterochromatin protein 1 | Immunofluorescence | Promoters | X-chromosome inactivation | epigenetics
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 40, p. 16699
X chromosome inactivation (XCI) is the most dramatic example of epigenetic silencing in eukaryotes. Once established, the inactivated X chromosome (Xi) remains... 
Genomics | Fluorescence | Epigenetics | Chromosomes | Cells
Journal Article
Journal of Genetics and Genomics, ISSN 1673-8527, 05/2018, Volume 45, Issue 5, pp. 227 - 236
Oncohistones are histones with high-frequency point mutations that are associated with tumorigenesis. Although each histone variant is encoded by multiple... 
Histone modification | Oncohistone | Pediatric cancer | Tumorigenesis | K27M MUTATIONS | HISTONE H3.3 MUTATIONS | CHROMATIN-STRUCTURE | DNA METHYLATION | GIANT-CELL TUMOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | REMODELING GENE ARID1A | SOMATIC MUTATIONS | GENETICS & HEREDITY | INTRINSIC PONTINE GLIOMAS | DRIVER MUTATIONS | PEDIATRIC GLIOMA
Journal Article
Journal Article