Angewandte Chemie (International Ed. in English), ISSN 1433-7851, 8/2011, Volume 50, Issue 33, pp. 7641 - 7644
Journal Article
Angewandte Chemie, ISSN 1433-7851, 08/2011, Volume 50, Issue 33, p. 7641
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2011, Volume 50, Issue 33, pp. 7641 - 7644
A common approach: Overall brevity in the synthesis of the title compounds (see scheme) is achieved by a sequential electrophilic aromatic substitution of...
Ritter reaction | indole alkaloids | natural products | cycloaddition | total synthesis | (+/-)-WELWITINDOLINONE-A ISONITRILE | NATURAL-PRODUCTS | HAPALOSIPHON-FONTINALIS | CHEMISTRY, MULTIDISCIPLINARY | VON BETA-CHLORVINYLALDEHYDEN | INDOLES | MARINE ALKALOIDS HAPALINDOLES | DIELS-ALDER REACTION | (+)-HAPALINDOLE-Q | SELECTIVITY | Indole Alkaloids - chemical synthesis | Indole Alkaloids - chemistry | Hydrocarbons, Chlorinated - chemistry | Stereoisomerism | Molecular Conformation
Ritter reaction | indole alkaloids | natural products | cycloaddition | total synthesis | (+/-)-WELWITINDOLINONE-A ISONITRILE | NATURAL-PRODUCTS | HAPALOSIPHON-FONTINALIS | CHEMISTRY, MULTIDISCIPLINARY | VON BETA-CHLORVINYLALDEHYDEN | INDOLES | MARINE ALKALOIDS HAPALINDOLES | DIELS-ALDER REACTION | (+)-HAPALINDOLE-Q | SELECTIVITY | Indole Alkaloids - chemical synthesis | Indole Alkaloids - chemistry | Hydrocarbons, Chlorinated - chemistry | Stereoisomerism | Molecular Conformation
Journal Article
Organic Letters, ISSN 1523-7060, 11/2007, Volume 9, Issue 24, pp. 5027 - 5029
A glycine Schiff base Michael addition is used in sequence with free radical-mediated aryl amination to ultimately arrive at the ambiguine G ABC-tricycle...
HAPALINDOLES | MILD | BUCHNER REACTION | MEDIATED VINYL AMINATION | DIELS-ALDER REACTION | ISONITRILE | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACID | ARYL AMINATION | DERIVATIVES | MARINE NATURAL-PRODUCTS | Indole Alkaloids - chemical synthesis | Indole Alkaloids - chemistry | Stereoisomerism | Molecular Conformation
HAPALINDOLES | MILD | BUCHNER REACTION | MEDIATED VINYL AMINATION | DIELS-ALDER REACTION | ISONITRILE | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACID | ARYL AMINATION | DERIVATIVES | MARINE NATURAL-PRODUCTS | Indole Alkaloids - chemical synthesis | Indole Alkaloids - chemistry | Stereoisomerism | Molecular Conformation
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2009, Volume 131, Issue 10, pp. 3470 - 3471
The first total synthesis of (+)-serratezomine A is described. Key aspects of the synthesis include (a) the first deployment of free-radical-mediated vinyl...
ASYMMETRIC TOTAL SYNTHESES | MEDIATED VINYL AMINATION | SOLVENT-DEPENDENT CHEMOSELECTIVITIES | MOSHER METHOD | STRATEGY | ENANTIOSELECTIVE TOTAL SYNTHESES | 1ST TOTAL-SYNTHESIS | ALPHA-AMINO-ACID | ARYL AMINATION | ALLYLTRIMETHYLSILANE | CHEMISTRY, MULTIDISCIPLINARY
ASYMMETRIC TOTAL SYNTHESES | MEDIATED VINYL AMINATION | SOLVENT-DEPENDENT CHEMOSELECTIVITIES | MOSHER METHOD | STRATEGY | ENANTIOSELECTIVE TOTAL SYNTHESES | 1ST TOTAL-SYNTHESIS | ALPHA-AMINO-ACID | ARYL AMINATION | ALLYLTRIMETHYLSILANE | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 02/2013, Volume 78, Issue 3, pp. 822 - 843
Serratezomine A is a member of the structurally diverse class of compounds known as the Lycopodium alkaloids. The key supporting studies and successful total...
ORGANIC-SYNTHESIS | FORMAL SYNTHESIS | CONVENIENT METHOD | ADDITION-REACTIONS | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACID | REDUCTIVE ALKYLATION | UNSATURATED AMINES | ARYL AMINATION | DIRECTED HYDROBORATION | UNIFIED TOTAL SYNTHESES | Amination | Oxidation-Reduction | Free Radicals - chemistry | Indolizines - chemistry | Stereoisomerism | Alkaloids - chemical synthesis | Indolizines - chemical synthesis | Molecular Structure | Lycopodium - chemistry | Alkaloids - chemistry | Measurement | Alkaloids | Analysis | Oxidation-reduction reaction | Chemical properties | Structure | Surface energy
ORGANIC-SYNTHESIS | FORMAL SYNTHESIS | CONVENIENT METHOD | ADDITION-REACTIONS | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACID | REDUCTIVE ALKYLATION | UNSATURATED AMINES | ARYL AMINATION | DIRECTED HYDROBORATION | UNIFIED TOTAL SYNTHESES | Amination | Oxidation-Reduction | Free Radicals - chemistry | Indolizines - chemistry | Stereoisomerism | Alkaloids - chemical synthesis | Indolizines - chemical synthesis | Molecular Structure | Lycopodium - chemistry | Alkaloids - chemistry | Measurement | Alkaloids | Analysis | Oxidation-reduction reaction | Chemical properties | Structure | Surface energy
Journal Article
Angewandte Chemie, ISSN 0044-8249, 08/2011, Volume 123, Issue 33, pp. 7783 - 7786
Gemeinsamer Ansatz: Durch die Synthese eines Neopentylchlorids als gemeinsamer Stammverbindung wird die Herstellung der Titelverbindungen über kurze Routen...
Indolalkaloide | Totalsynthesen | Ritter‐Reaktion | Cycloadditionen | Naturstoffe
Indolalkaloide | Totalsynthesen | Ritter‐Reaktion | Cycloadditionen | Naturstoffe
Journal Article
Angewandte Chemie, ISSN 0044-8249, 08/2011, Volume 123, Issue 33, pp. 7783 - 7786
Journal Article
Angewandte Chemie, ISSN 0044-8249, 08/2011, Volume 123, Issue 33, p. 7783
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2009, Volume 131, Issue 10, pp. 3470 - 3471
Journal Article
01/2011, ISBN 1303564319
Dissertation
Journal of the American Chemical Society, ISSN 0002-7863, 03/2009, Volume 131, Issue 10, p. 3470
The first total synthesis of (+)-serratezomine A is described. Key aspects of the synthesis include (a) the first deployment of free-radical-mediated vinyl...
Indolizines - chemical synthesis | Molecular Structure | Magnetic Resonance Spectroscopy | Lycopodium - chemistry | Indolizines - chemistry | Cerium | Substitution reactions | Alkaloids | Chemical properties | Aldehydes | Analysis
Indolizines - chemical synthesis | Molecular Structure | Magnetic Resonance Spectroscopy | Lycopodium - chemistry | Indolizines - chemistry | Cerium | Substitution reactions | Alkaloids | Chemical properties | Aldehydes | Analysis
Journal Article
The development of new chemical methods to tackle synthetic challenges is presented in this dissertation. Application of these methods has led to the...
Chemistry
Chemistry
Dissertation
ChemInform, ISSN 0931-7597, 04/2008, Volume 39, Issue 17, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform of an...
alkaloids
alkaloids
Journal Article
06/2019
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of...
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
03/2019
La presente invención provee un compuesto de fórmula (I) o una sal farmacéuticamente aceptable de este, composiciones farmacéuticas que comprenden un compuesto...
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HETEROCYCLIC COMPOUNDS | HUMAN NECESSITIES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HETEROCYCLIC COMPOUNDS | HUMAN NECESSITIES
Patent
03/2019
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of...
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent
03/2019
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of...
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | HYGIENE | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
ChemInform, ISSN 0931-7597, 07/2009, Volume 40, Issue 30, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform of an...
fused pyridine derivatives | alkaloids
fused pyridine derivatives | alkaloids
Journal Article
09/2003, 7
Patent
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