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1. Full Text Synthesis and derivatization of the Bis(amido)-γ3- cyclodiphosphazanes cis-[R′(H)NP(μ-NR)]2, including a rare example, trans-[tBu(H)N(Se)P(μ-NCy)]2, showing intermolecular Se⋯H-O hydrogen bonding
by Chandrasekaran, P and Mague, Joel T and Balakrishna, Maravanji S
European Journal of Inorganic Chemistry, ISSN 1434-1948, 05/2011, Issue 14, pp. 2264 - 2272
Heterocycles | Hydrogen bonds | Phosphorus | Chalcogens | Selenium
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2. Full Text Prediction of Detonation Velocity and N−O Composition of High Energy C−H−N−O Explosives by Means of Artificial Neural Networks
by Chandrasekaran, Nichith and Oommen, Charlie and Kumar, V. R. Sanal and Lukin, Alexander N and Abrukov, Victor S and Anufrieva, Darya A
Propellants, Explosives, Pyrotechnics, ISSN 0721-3115, 05/2019, Volume 44, Issue 5, pp. 579 - 587
The possibilities of the application of Data Science Methods in predicting certain macroscopic properties have been examined in energetic compounds. Artificial... 
Data science | High energetic materials | Detonation velocity | Multifactor computational models | Knowledge Base Formatting | Artificial neural networks | ENGINEERING, CHEMICAL | IMPACT SENSITIVITY | CHNOFCL | CHEMISTRY, APPLIED | Explosives | Scientists | Neural networks | Analysis | Organic chemistry | Data points | Detonation | Predictions | Chemical composition
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3. Full Text Synthesis and Derivatization of the Bis(amido)-lambda(3)-cyclodiphosphazanes cis-[R '(H)NP(mu-NR)](2), Including a Rare Example, trans-[tBu(H)N(Se)P(mu-NCy)](2), Showing Intermolecular Se center dot center dot center dot H-O Hydrogen Bonding
by Chandrasekaran, P and Mague, JT and Balakrishna, MS
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, ISSN 1434-1948, 05/2011, Issue 14, pp. 2264 - 2272
The reaction of PCl3 with CyNH2 in a 1: 3 ratio afforded the dichloro-lambda(3)-cyclodiphosphazane, cis-[ClP(mu-NCy)](2) (2), whereas the corresponding 1: 5... 
Heterocycles | Phosphorus | CRYSTAL-STRUCTURES | Chalcogens | PHOSPHAZANE OLIGOMERS | CHEMISTRY, INORGANIC & NUCLEAR | HETEROMETALLIC COMPLEXES | REVERSIBLE CONVERSION | Hydrogen bonds | TRANS ISOMERS | CYCLODIPHOSPHAZANE | MOLECULAR-STRUCTURES | Selenium | ETHENE POLYMERIZATION | 1ST STRUCTURAL-CHARACTERIZATION | SOLID-STATE STRUCTURES
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4. Full Text Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
by Cannon, Christopher P and Blazing, Michael A and Giugliano, Robert P and McCagg, Amy and White, Jennifer A and Theroux, Pierre and Darius, Harald and Lewis, Basil S and Ophuis, Ton Oude and Jukema, J. Wouter and De Ferrari, Gaetano M and Ruzyllo, Witold and De Lucca, Paul and Im, KyungAh and Bohula, Erin A and Reist, Craig and Wiviott, Stephen D and Tershakovec, Andrew M and Musliner, Thomas A and Braunwald, Eugene and Califf, Robert M and IMPROVW-IT Investigators and IMPROVE-IT Investigators
The New England Journal of Medicine, ISSN 0028-4793, 06/2015, Volume 372, Issue 25, pp. 2387 - 2397
In this trial, patients with an acute coronary syndrome within the previous 10 days were randomly assigned to simvastatin plus either ezetimibe or placebo. At... 
CHOLESTEROL ABSORPTION | CARDIAC OUTCOMES | MEDICINE, GENERAL & INTERNAL | MYOCARDIAL-INFARCTION | EFFICACY | CARDIOVASCULAR OUTCOMES | CLINICAL-TRIALS | SIMVASTATIN | PRIMARY PREVENTION | IMPROVE-IT | ATORVASTATIN | Simvastatin - therapeutic use | Double-Blind Method | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Azetidines - adverse effects | Ezetimibe | Kaplan-Meier Estimate | Male | Anticholesteremic Agents - adverse effects | Acute Coronary Syndrome - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Azetidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Cholesterol, LDL - blood | Female | Aged | Drug Therapy, Combination | Usage | Simvastatin | Analysis | Practice guidelines (Medicine) | Dosage and administration | Drug therapy, Combination | Acute coronary syndrome | Drug therapy | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Angina | Cholesterol | Intestine | Gallbladder | Acute coronary syndromes | Cardiovascular diseases | Statins | Pharmaceuticals | Cancer | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
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5. Full Text Identification of novel NAD(P)H dehydrogenase [quinone] 1 antagonist using computational approaches
by Selvakumar, Rajendran and Anantha Krishnan, Dhanabalan and Ramakrishnan, Chandrasekaran and Velmurugan, Devadasan and Gunasekaran, Krishnasamy
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 2019, pp. 1 - 15
NAD(P)H: quinone oxidoreductase 1 (NQO1) inhibitors are proved as promising therapeutic agents against cancer. This study is to determine potent... 
NQO1 | virtual screening | 3D-QSAR | pharmacophore modeling | induced fit docking (IFD) | MDS | cancer and MM/GBSA
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6. Full Text Use of 2–4 H magnetic resonance spectroscopy (MRS) biomarkers to predict 48 H MRS and histology outcome biomarkers in a piglet model of perinatal asphyxia
by Raivich, G and Chandrasekaran, M and Faulkner, S and Bainbridge, A and Liu, M and Cady, E and Hristova, M and Robertson, N
Archives of Disease in Childhood - Fetal and Neonatal Edition, ISSN 1359-2998, 06/2011, Volume 96, Issue Suppl 1, pp. Fa29 - Fa29
Research into treatment of stroke and neonatal hypoxic-ischaemic (HI) insult has been beset by high variability in clinical and histopathology outcome despite... 
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7. Full Text H 2 O 2 and mTOR control the senescence-associated secretory phenotype by coordinating Ca 2+ transients through TRPC6 expression and activation
by Chandrasekaran, Akshaya and Zhang, Xuexin and Lee, May Y and Shapiro, Russell and Trebak, Mohamed and Melendez, Juan Andres
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 55 - 56
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8. Full Text The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
by Olldashi, Fatos and Kerçi, Mihal and Zhurda, Tefik and Ruçi, Klotilda and Banushi, Arben and Traverso, Mario Sardón and Jiménez, Juan and Balbi, Jorge and Dellera, Christian and Svampa, Silvana and Quintana, Gustavo and Piñero, Gustavo and Teves, Jorge and Seppelt, Ian and Mountain, David and Balogh, Zsolt and Zaman, Maniruz and Druwé, Patrick and Rutsaert, Robert and Mazairac, Guy and Pascal, Fogang and Yvette, Zognou and Chancellin, Djeuchon and Okwen, Patrick and Djokam-Liapoe, Jules and Jangwa, Ernest and Mbuagbaw, Lawrence and Fointama, Ninying and Baillie, Frank and Jiang, Ji-Yao and Gao, Guo-Yi and Bao, Yin-Hui and Morales, Carlos and Sierra, Juan and Naranjo, Santiago and Correa, Camilo and Gómez, Carolina and Herrera, Jorge and Caicedo, Liliana and Rojas, Alexei and Pastas, Henry and Miranda, Hugo and Constaín, Alfredo and Perdomo, Mayla and Muñoz, Diego and Duarte, Álvaro and Vásquez, Edwin and Ortiz, Camilo and Ayala, Bernardo and Delgado, Hernán and Benavides, Gloria and Rosero, Lorena and Mejía-Mantilla, Jorge and Varela, Ana and Calle, Maríaisabel and Castillo, José and García, Alberto and Ciro, Juan and Villa, Clara and Panesso, Roberto and Flórez, Luz and Gallego, Argemiro and Puentes-Manosalva, Fabián and Medina, Leonor and Márquez, Kelly and Romero, Adalgiza Reyes and Hernández, Ricardo and Martínez, Julio and Gualteros, Wilson and Urbina, Zulma and Velandia, Julio and Benítez, Federico and Trochez, Adolfo and Villarreal, Andrés and Pabón, Pamela and López, Héctor and Quintero, Laureano and Rubiano, Andrés and Tamayo, Juan and Piñera, Marjoris and Martínez, Daimi and Martínez, Heriberto and Casola, Eugenio and Domínguez, Mario and Herrera, Carlos and Iraola, Marcos and Rojas, Omar and Pastrana, Irene and Rodríguez, Daniel and De La Campa, Sergio Álvarez and Fortún, Thorvald and Larrea, Martha and Aragón, Lensky and Madrazo, Aida and Svoboda, Petr and Izurieta, Mario and Daccach, Alberto and Altamirano, Mónica and Ortega, Antonio and Cárdenas, Bolívar and ... and CRASH-2 Collaborators and CRASH-2 collaborators
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9771, pp. 1096 - 1101.e2
Summary Background The aim of the CRASH-2 trial was to assess the effects of early administration of tranexamic acid on death, vascular occlusive events, and... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | COAGULOPATHY | Antifibrinolytic Agents - therapeutic use | Hemorrhage - drug therapy | Time Factors | Humans | Wounds and Injuries - complications | Hemorrhage - mortality | Adult | Logistic Models | Tranexamic Acid - therapeutic use | Clinical trials | Data collection | Blood pressure | Statistical analysis | Acids | Charitable foundations
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