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PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e31458
Hepatitis B virus X protein (HBx) plays an important role in the development of hepatocellular carcinoma (HCC). However, the mechanism remains unclear.... 
CALPAIN SMALL-SUBUNIT | HEPATOCELLULAR-CARCINOMA CELLS | IN-VITRO | OSTEOPONTIN | TUMOR PROGRESSION | INCREASES MIGRATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | ARACHIDONIC-ACID METABOLISM | HBX PROTEIN | UP-REGULATION | Osteopontin - genetics | RNA, Small Interfering - genetics | Calpain - metabolism | Luciferases - metabolism | Arachidonate 5-Lipoxygenase - genetics | Osteopontin - antagonists & inhibitors | Humans | Osteopontin - metabolism | Calpain - genetics | Cell Movement - physiology | Carcinoma, Hepatocellular - genetics | Arachidonate 5-Lipoxygenase - chemistry | Trans-Activators - genetics | Liver Neoplasms - pathology | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Arachidonate 5-Lipoxygenase - metabolism | Enzyme-Linked Immunosorbent Assay | Liver Neoplasms - genetics | Signal Transduction | RNA, Messenger - genetics | Blotting, Western | Feedback, Physiological | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Trans-Activators - metabolism | Calpain - antagonists & inhibitors | Carcinoma, Hepatocellular - metabolism | Transcription factors | Leukocyte migration | Laboratories | Viruses | Amino acids | Smooth muscle | Hepatocellular carcinoma | Biochemistry | Metastasis | Hepatoma | Promotion | Positive feedback | Cell adhesion & migration | Proteins | Hepatitis | Liver cancer | Angiogenesis | Biomedical materials | Cell growth | Education | Arachidonate 5-lipoxygenase | Fibroblasts | Biocompatibility | Life sciences | Hepatitis B virus | Medical research | NF-κB protein | Antigens | Osteopontin | Calpain | Breast cancer | Gene expression | Studies | Polymerase chain reaction | Lymphocytes B | Liquid oxygen | X protein | Lipoxygenase | Molecular biology | Cell migration | Hepatitis B | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, p. e19518
Hepatitis B virus X protein (HBx) plays important roles in the development of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) contribute to cancer... 
HEPATOCELLULAR-CARCINOMA CELLS | MIR-29 | OVEREXPRESSION | GENE | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | CHRONIC LYMPHOCYTIC-LEUKEMIA | HUMAN CANCERS | KAPPA-B | HBX PROTEIN | EXPRESSION | Phosphorylation | Humans | 3' Untranslated Regions - genetics | MicroRNAs - metabolism | Cell Movement - genetics | Cell Movement - physiology | Proto-Oncogene Proteins c-akt - genetics | RNA Interference | Carcinoma, Hepatocellular - genetics | Trans-Activators - genetics | Proto-Oncogene Proteins c-akt - metabolism | PTEN Phosphohydrolase - genetics | Liver Neoplasms - genetics | PTEN Phosphohydrolase - metabolism | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Hep G2 Cells | Animals | Liver Neoplasms - metabolism | Cell Line, Tumor | Trans-Activators - metabolism | Mice | MicroRNAs - genetics | In Vitro Techniques | Carcinoma, Hepatocellular - metabolism | MicroRNA | Analysis | Genes | Luciferase | Genetic engineering | B cells | Hepatitis B virus | Hepatoma | Hepatitis B | Cell culture | Transcription factors | Leukocyte migration | Laboratories | Leukemia | AKT protein | Viruses | Hepatocellular carcinoma | Kinases | Phosphatase | Proteins | Hepatitis | Liver cancer | Clonal deletion | Transgenic animals | Education | Rodents | Deletion | Life sciences | Tumorigenesis | Medical research | Transgenic mice | MiRNA | Breast cancer | X cells | Gene expression | Ribonucleic acid--RNA | Suppressors | Lymphocytes B | 3' Untranslated regions | MicroRNAs | X protein | Molecular biology | Cell migration | Binding sites | PTEN protein | Tumors | Cancer | RNA | Ribonucleic acid
Journal Article
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 08/2010, Volume 10, Issue 3, pp. 232 - 241
MicroRNAs (miRNAs), non-coding RNAs that function as post-transcriptional gene regulators, play a pivotal role in cancer development. In the present study, we... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | microRNA | Breast cancer | Complement attack | Complement-dependent cytotoxicity | Complement-regulatory protein | complement attack | ONCOLOGY | GENES | breast cancer | CHRONIC LYMPHOCYTIC-LEUKEMIA | CD59 | PROLIFERATION | complement-regulatory protein | MICRORNA EXPRESSION PROFILES | complement-dependent cytotoxicity | LINES
Journal Article
Analytical Chemistry, ISSN 0003-2700, 04/2016, Volume 88, Issue 7, pp. 4048 - 4054
Journal Article
FEBS Letters, ISSN 0014-5793, 09/2012, Volume 586, Issue 19, pp. 3215 - 3221
► A cell model of HBx-integration is established using human normal liver cells. ► The recombination of HBx/ core sequence/subtelomeric DNA is required for... 
Integration | Recombination | Hepatocarcinogenesis | HBx | Subtelomeric | hematoxylin and eosin | hepatitis B virus X gene | hepatitis B virus | H&E | activator protein-1 | HCC | nuclear factor-kappa B | AFP | AP-1 | α-fetal protein | NF-κB | RT-PCR | FCS | fetal calf serum | hTERT | human telomerase reverse transcriptase | HBV | hepatocellular carcinoma | reverse-transcription polymerase chain reaction | MUTANT | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEPATOMA-CELLS | CELL-PROLIFERATION | IDENTIFICATION | CELL BIOLOGY | BIOPHYSICS | LIVER | HUMAN HEPATOCELLULAR-CARCINOMA | EXPRESSION | Liver Neoplasms - virology | Virus Integration - genetics | Liver Neoplasms - genetics | Hepatitis B virus - pathogenicity | Humans | Molecular Sequence Data | Carcinoma, Hepatocellular - virology | Hepatitis B virus - physiology | Hep G2 Cells | Liver Neoplasms - etiology | Models, Biological | Recombination, Genetic | Base Sequence | Carcinoma, Hepatocellular - genetics | Genes, Viral | Hepatitis B virus - genetics | Trans-Activators - genetics | Carcinoma, Hepatocellular - etiology | DNA, Neoplasm - genetics | DNA, Viral - genetics | Alu Elements | Cell Line, Transformed | Telomere - genetics | Proteins | Liver cancer | Analysis | Oncology, Experimental | Genes | DNA | Genetic research | Hepatitis B virus | Research | Telomerase | Hepatitis B | Cancer
Journal Article
Journal Article
Plant Biotechnology Journal, ISSN 1467-7644, 10/2014, Volume 12, Issue 8, pp. 1132 - 1142
Journal Article
Journal Article
Journal Article