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1. Full Text Exosomes: immune properties and potential clinical implementations
by Chaput, Nathalie and Chaput, Nathalie and Théry, Clotilde and Théry, Clotilde
Seminars in immunopathology, ISSN 1863-2297, 9/2011, Volume 33, Issue 5, pp. 419 - 440
Antigen presentation | Biomedicine | Immunology | Immunomodulation | Internal Medicine | Exosomes | Intercellular communication | Pathology | Life Sciences & Biomedicine | Science & Technology | Exosomes - metabolism | Neoplasms - metabolism | Antigen-Presenting Cells - metabolism | Communicable Diseases - therapy | Humans | Cell Communication | Antigen Presentation - immunology | Neoplasms - therapy | Animals | Biological Transport | Neoplasms - immunology | Immunotherapy | Communicable Diseases - immunology | Exosomes - immunology | Exosomes - chemistry | Antigens | RNA | Membrane proteins | Protein binding | Index Medicus
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2. Full Text Hyperprogressive disease is a new pattern of progression in cancer patients treated by anti-PD-1/PD-L1
by Champiat, Stéphane and Dercle, Laurent and Ammari, Samy and Massard, Christophe and Hollebecque, Antoine and Postel-Vinay, Sophie and Chaput, Nathalie and Eggermont, Alexander and Marabelle, Aurélien and Soria, Jean-Charles and Ferté, Charles
Clinical cancer research, ISSN 1078-0432, 04/2017, Volume 23, Issue 8, pp. 1920 - 1928
Life Sciences & Biomedicine | Oncology | Science & Technology | Humans | Middle Aged | Kaplan-Meier Estimate | Proportional Hazards Models | Neoplasms - mortality | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Disease Progression | Neoplasms - drug therapy | Young Adult | Disease-Free Survival | B7-H1 Antigen - antagonists & inhibitors | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Aged | Neoplasms - pathology | Clinical Trials, Phase I as Topic | Drugs | Medical research | Therapy | Growth rate | PD-1 protein | Clinical trials | Medical records | Survival | Patients | Immunosuppressive agents | Immune checkpoint | Experimental design | Older people | PD-L1 protein | Lesions | Cancer | Geriatrics | Index Medicus
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3. Full Text Predictive biomarkers of response for immune checkpoint inhibitors in non–small-cell lung cancer
by Prelaj, Arsela and Tay, Rebecca and Ferrara, Roberto and Chaput, Nathalie and Besse, Benjamin and Califano, Raffaele
European journal of cancer (1990), ISSN 0959-8049, 01/2019, Volume 106, pp. 144 - 159
NSCLC | Immunotherapy | Predictive biomarkers | Lung cancer | PD-L1 | Tumour mutational burden | Microsatellite instability | Tumour microenvironment | Life Sciences & Biomedicine | Oncology | Science & Technology | Lung Neoplasms - drug therapy | Predictive Value of Tests | Lung Neoplasms - mortality | Humans | Transcriptome | Tumor Microenvironment | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Biomarkers, Tumor - antagonists & inhibitors | Lung Neoplasms - genetics | Risk Assessment | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Risk Factors | Treatment Outcome | B7-H1 Antigen - immunology | Carcinoma, Non-Small-Cell Lung - mortality | Carcinoma, Non-Small-Cell Lung - immunology | Antineoplastic Agents, Immunological - adverse effects | Lung Neoplasms - immunology | B7-H1 Antigen - antagonists & inhibitors | Antineoplastic Agents, Immunological - therapeutic use | Biomarkers, Tumor - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Programmed Cell Death 1 Receptor - immunology | Biomarkers, Tumor - immunology | Immune response | Lung cancer, Non-small cell | Biological markers | Tumors | Cell survival | Toxicity | Non-small cell lung carcinoma | Anticancer properties | Immune checkpoint | Peripheral blood | Biomarkers | Immune system | Apoptosis | Cancer | Index Medicus
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4. Foxp3+ cells are running the show in patients with surgically resected nonsmall cell lung cancer
by Chaput, Nathalie and Marabelle, Aurelien
The European respiratory journal, ISSN 0903-1936, 12/2015, Volume 46, Issue 6, pp. 1541 - 1543
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Running | Prognosis | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Humans
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5. Full Text Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
by Marie Vétizou and Jonathan M. Pitt and Romain Daillère and Patricia Lepage and Nadine Waldschmitt and Caroline Flament and Sylvie Rusakiewicz and Bertrand Routy and Maria P. Roberti and Connie P. M. Duong and Vichnou Poirier-Colame and Antoine Roux and Sonia Becharef and Silvia Formenti and Encouse Golden and Sascha Cording and Gerard Eberl and Andreas Schlitzer and Florent Ginhoux and Sridhar Mani and Takahiro Yamazaki and Nicolas Jacquelot and David P. Enot and Marion Bérard and Jérôme Nigou and Paule Opolon and Alexander Eggermont and Paul-Louis Woerther and Elisabeth Chachaty and Nathalie Chaput and Caroline Robert and Christina Mateus and Guido Kroemer and Didier Raoult and Ivo Gomperts Boneca and Franck Carbonnel and Mathias Chamaillard and Laurence Zitvogel
Science (American Association for the Advancement of Science), ISSN 0036-8075, 11/2015, Volume 350, Issue 6264, pp. 1079 - 1084
REPORTS | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Germ-Free Life - immunology | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Intestines - immunology | Dysbiosis - immunology | Immunotherapy | Aged, 80 and over | Adult | Female | Skin Neoplasms - therapy | Bacteroides - immunology | Mice, Inbred C57BL | CTLA-4 Antigen - immunology | Fecal Microbiota Transplantation | Animals | Gastrointestinal Microbiome - drug effects | Intestines - microbiology | Immunologic Memory | T-Lymphocytes - immunology | Aged | Anti-Bacterial Agents - pharmacology | Mice | Gastrointestinal Microbiome - immunology | CTLA-4 Antigen - antagonists & inhibitors | Melanoma - therapy | Usage | Cell receptors | Care and treatment | Microbiota (Symbiotic organisms) | Health aspects | Methods | Cancer | Stomach | Microbiology | Cells | Index Medicus | Microorganisms | Effectiveness | Antibodies | Patients | Tumors | Anticancer properties | Life Sciences
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6. Full Text Immunosenescence and immunecheckpoint inhibitors in non-small cell lung cancer patients: Does age really matter?
by Ferrara, Roberto and Mezquita, Laura and Auclin, Edouard and Chaput, Nathalie and Besse, Benjamin
Cancer treatment reviews, ISSN 0305-7372, 11/2017, Volume 60, pp. 60 - 68
Immunosenescence | Anti-PD1/PD-L1 mAb | Immune checkpoint inhibitors | Elderly | Age | Non-small cell lung cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - drug therapy | Cell Cycle Checkpoints | Immunotherapy - methods | Lung Neoplasms - immunology | Humans | Antineoplastic Agents - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Immunity, Cellular | Molecular Targeted Therapy - methods | Lung cancer, Small cell | Care and treatment | T cells | Lung cancer, Non-small cell | Analysis | Immunotherapy | Index Medicus
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7. Full Text Anticancer immunotherapy by CTLA-4 blockade： obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25
by Dalil Hannani Marie Vetizou David Enot Sylvie Rusakiewicz Nathalie Chaput David Klatzmann Melanie Desbois Nicolas Jacquelot Nadege Vimond Salem Chouaib Christine Mateus James P Allison Antoni Ribas Jedd D Wolchok Jianda Yuan Philip Wong Michael Postow Andrzej Mackiewicz Jacek Mackiewicz Dirk Schadendorff Dirk Jaeger Alan J Korman Keith Bahjat Michele Maio Luana Calabro Michele WL Teng Mark J Smyth Alexander Eggennont Caroline Robert Guido Kroemer Laurence Zitvogel
Cell research, ISSN 1001-0602, 2015, Volume 25, Issue 2, pp. 208 - 224
免疫治疗 | 抗癌作用 | 可溶性 | 生物标志物 | CTLA-4 | IL-2 | 细胞毒性T淋巴细胞 | sCD25 | tumor immunotherapy | ipilimumab | cancer | CTLA-4 blockade | CD122 | Index Medicus | Life Sciences | Immunotherapy | Immunology
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