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PLoS Computational Biology, ISSN 1553-734X, 04/2016, Volume 12, Issue 4, p. e1004827
Understanding the molecular pathways by which oncogenes drive cancerous cell growth, and how dependence on such pathways varies between tumors could be highly... 
BREAST-CANCER | DRUG-SENSITIVITY | COMBINATIONS | GENOMICS | MEK INHIBITION | PATHWAY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | RESISTANCE | KINASE INHIBITORS | NETWORKS | DISCOVERY | Neoplasms - metabolism | Receptor, ErbB-3 - metabolism | Humans | ErbB Receptors - genetics | Receptor, ErbB-2 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | RNA, Messenger - metabolism | RNA, Neoplasm - metabolism | Breast Neoplasms - metabolism | Gene Knockdown Techniques | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | MAP Kinase Signaling System - genetics | Neoplasms - genetics | Biomarkers, Tumor - metabolism | Female | ErbB Receptors - metabolism | RNA, Messenger - genetics | Computational Biology | Receptor, ErbB-3 - genetics | Phosphatidylinositol 3-Kinases - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Genes, erbB-2 | Cell Line, Tumor | RNA, Neoplasm - genetics | Biomarkers, Tumor - genetics | Mutation | Neoplasms - pathology | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Care and treatment | Genetic markers | Oncology, Experimental | Genetic aspects | Research | Drug resistance | Cancer | Cellular signal transduction | Gene expression | Health aspects | Cancer cells | Mitogen-activated protein kinases | Drugs | Funding | Bias | Mortality | Breast cancer | Kinases | Cancer therapies | Patients | Growth models | Data bases | Proteins | Cell growth | Dependence | Biomarkers | Ligands | Protein expression | Tumors | Logistics
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3324 - 3324
Abstract Introduction Targeted antibody drug conjugates (ADCs) to mouse CD45 or mouse CD117 have recently been shown to effectively prepare immunocompetent... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3314 - 3314
Abstract Background: Genotoxic conditioning prior to allogeneic and autologous bone marrow transplantation (BMT) limits the use of these potentially curative... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3316 - 3316
Abstract Background. Allogeneic bone marrow transplant (BMT) is a potentially curative approach in patients with refractory or high risk hematologic... 
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 09/2008, Volume 7, Issue 9, pp. 2913 - 2923
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S188 - S189
Bone Marrow Transplant (BMT) is a potentially curative treatment for malignant and non-malignant blood disorders. Current regimens for patient preparation, or... 
Medical research | Mortality | Antibodies | Transplantation | Antineoplastic agents | T cells | Biopharmaceutics | Antimitotic agents | Viral antibodies | Analysis | Stem cells | Medicine, Experimental | Bone marrow
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S32 - S32
Bone Marrow Transplant (BMT) is a potentially curative treatment for malignant and non-malignant blood disorders. Current regimens for patient preparation, or... 
Usage | Mortality | Leukemia | Antibodies | Transplantation | Permeability | Biopharmaceutics | Hematopoietic stem cells | Viral antibodies | Enzyme inhibitors | Bone marrow | Primates | Lymphomas
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S100 - S101
In the Kasumi model, a single dose of 0.3 mg/kg anti-CD117-AM on day 7 or 42 after inoculation markedly increased survival (median >240 days) compared to... 
Viral antibodies | Analysis | Mortality | Leukemia | Patient outcomes | Antibodies | Bone marrow | Transplantation | Hematopoietic stem cells | Biopharmaceutics | Analog to digital converters
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S29 - S30
Current regimens for patient preparation, or conditioning, prior to bone marrow transplantation (BMT) limit the use of this curative procedure due to... 
Viral antibodies | Analysis | Leukemia | Stem cells | Primates | Antibodies | Bone marrow | Transplantation | Health aspects | Biopharmaceutics
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 03/2019, Volume 25, Issue 3, pp. S100 - S100
In the Kasumi model, a single dose of 0.3 mg/kg anti-CD117-AM on day 7 or 42 after inoculation markedly increased survival (median >240 days) compared to... 
Viral antibodies | Analysis | Leukemia | Patient outcomes | Mortality | Antibodies | Bone marrow | Transplantation | Hematopoietic stem cells | Biopharmaceutics | Analog to digital converters
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 03/2012, Volume 11, Issue 3, pp. 582 - 593
Journal Article
Journal Article
Protein Engineering, Design & Selection, ISSN 1741-0126, 07/2006, Volume 19, Issue 7, p. 299
  The chimeric anti-CD30 IgG1, cAC10, conjugated to eight equivalents of monomethyl auristatin E (MMAE) was previously shown to have potent antitumor activity... 
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 18, pp. 4352 - 4361
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4526 - 4526
Abstract Introduction Bone Marrow Transplant (BMT) is a potentially curative treatment for malignant and non-malignant blood disorders and has demonstrated... 
Journal Article
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