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Nature Medicine, ISSN 1078-8956, 04/2012, Volume 18, Issue 4, pp. 521 - 528
Tyrosine kinase inhibitors (TKIs) elicit high response rates among individuals with kinase-driven malignancies, including chronic myeloid leukemia (CML) and... 
CHRONIC MYELOGENOUS LEUKEMIA | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | GEFITINIB | BIOCHEMISTRY & MOLECULAR BIOLOGY | EYE DISEASES | CHRONIC MYELOID-LEUKEMIA | CELL BIOLOGY | CELL LUNG-CANCER | FACTOR RECEPTOR EGFR | GROWTH | ACTIVATING MUTATIONS | MUTANT EGFR | Enzyme-Linked Immunosorbent Assay - methods | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Follow-Up Studies | Apoptosis - drug effects | Humans | Middle Aged | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Male | BH3 Interacting Domain Death Agonist Protein - genetics | Dose-Response Relationship, Drug | Protein Isoforms - metabolism | Transfection | Bcl-2-Like Protein 11 | Statistics, Nonparametric | Aged, 80 and over | Apoptosis Regulatory Proteins - genetics | Adult | Female | Gene Expression Regulation, Neoplastic - drug effects | Lung Neoplasms - genetics | Annexins - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Gene Frequency | Exons - genetics | Genotype | Proto-Oncogene Proteins - genetics | International Cooperation | Drug Resistance, Neoplasm - genetics | Cell Line, Tumor | Polymorphism, Genetic - genetics | Aged | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Cohort Studies | Drug Resistance, Neoplasm - drug effects | Protein Isoforms - genetics | RNA, Small Interfering - metabolism | Sequence Deletion - genetics | Antimitotic agents | Physiological aspects | Protein tyrosine kinase | Dosage and administration | Genetic aspects | Research | Antineoplastic agents | Tumor proteins | Genetic polymorphisms | Inhibitor drugs | Mutation | Kinases | Gene expression | Apoptosis | Polymorphism | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 06/2005, Volume 65, Issue 11, pp. 4918 - 4928
Hypoxia-inducible factor-1 (HIF-1) is a transcriptional complex that is activated in response to hypoxia and growth factors. HIF-1 plays a central role in... 
TARGET | FACTOR-1-ALPHA | ANGIOGENESIS | ONCOLOGY | PATHWAY | TOPOISOMERASE-I | TUMOR-GROWTH | HIF-ALPHA | CANCER | EXPRESSION | PAS DOMAIN PROTEIN
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0134102 - e0134102
Sunitinib is a tyrosine kinase inhibitor used as first-line treatment for metastatic renal cell carcinoma (mRCC). Asian ethnicity has been previously... 
INTERFERON-ALPHA | 1ST-LINE SUNITINIB | VEGF | MULTIDISCIPLINARY SCIENCES | TYROSINE KINASE INHIBITOR | MDR1 GENE | ANTITUMOR-ACTIVITY | CANCER | SINGLE-NUCLEOTIDE POLYMORPHISMS | PREDICTIVE FACTORS | ENDOTHELIAL GROWTH-FACTOR | Haplotypes | Kidney Neoplasms - genetics | Singapore | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Carcinoma, Renal Cell - genetics | Male | Antineoplastic Agents - therapeutic use | Young Adult | fms-Like Tyrosine Kinase 3 - genetics | Neoplasm Metastasis | Antineoplastic Agents - adverse effects | Drug-Related Side Effects and Adverse Reactions - genetics | Pyrroles - adverse effects | Adult | Female | Carcinoma, Renal Cell - drug therapy | Pyrroles - therapeutic use | Carcinoma, Renal Cell - ethnology | Kidney Neoplasms - ethnology | Genetic Predisposition to Disease - genetics | Gene Frequency | Genotype | Treatment Outcome | Disease-Free Survival | Indoles - adverse effects | Adolescent | Genetic Predisposition to Disease - ethnology | Indoles - therapeutic use | Aged | Polymorphism, Single Nucleotide | Kidney Neoplasms - drug therapy | ATP Binding Cassette Transporter, Sub-Family B - genetics | Care and treatment | Platelet-derived growth factor | Research | Carcinoma, Renal cell | Vascular endothelial growth factor | Risk factors | Bioengineering | Populations | Toxicity | Leukemia | Genes | Oncology | Metastasis | Cancer therapies | Metastases | Population | Bioindicators | Drug dosages | Protein-tyrosine kinase | Genotypes | Neutropenia | Tyrosine | Medical research | Cell survival | Pharmacology | FDA approval | Minority & ethnic groups | Patients | Survival | Studies | Biomarkers | Nanotechnology | Clear cell-type renal cell carcinoma | Index Medicus
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 04/2004, Volume 24, Issue 7, pp. 2905 - 2914
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
CANCER-CELLS | FACTOR 1-ALPHA | TRANSCRIPTIONAL ACTIVATION | OXYGEN-TENSION | PROLYL HYDROXYLATION | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MDM2 | TUMOR-SUPPRESSOR PROTEIN | HIF-ALPHA | P53 | CELL BIOLOGY | Cell Growth and Development
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 2/2014, Volume 73, Issue 2, pp. 381 - 388
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 02/2014, Volume 32, Issue 4, pp. 439 - 439
Conference Proceeding
Clinical Genitourinary Cancer, ISSN 1558-7673, 2015, Volume 13, Issue 4, pp. e285 - e295
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 02/2014, Volume 32, Issue 4, pp. 200 - 200
Conference Proceeding
Journal Article
Proceedings of Singapore Healthcare, ISSN 2010-1058, 3/2011, Volume 20, Issue 1, pp. 1 - 2
Journal Article
Proceedings of Singapore Healthcare, ISSN 2010-1058, 2011, Volume 20, Issue 1, pp. 1 - 2
Journal Article
Journal Article
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