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PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e87309
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a naphthoquinone derivative from the roots of plant Plumbago zeylanica and belongs to one of the largest... 
IN-VITRO | PROTEIN | CANCER CELLS | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | STAT3 | CELL-CYCLE ARREST | SCORING FUNCTIONS | NF-KAPPA-B | BCL-2 FAMILY | PAN-ACTIVE INHIBITORS | Proto-Oncogene Proteins c-akt - chemistry | Humans | Molecular Conformation | Models, Molecular | Antineoplastic Agents, Phytogenic - chemistry | NF-kappa B - metabolism | Naphthoquinones - pharmacology | NF-kappa B - chemistry | STAT3 Transcription Factor - chemistry | Databases, Pharmaceutical | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Class Ib Phosphatidylinositol 3-Kinase - chemistry | Class Ib Phosphatidylinositol 3-Kinase - metabolism | Protein Binding | Ligands | Naphthoquinones - chemistry | Proto-Oncogene Proteins c-bcl-2 - chemistry | Antineoplastic Agents, Phytogenic - metabolism | Mice | Antineoplastic Agents, Phytogenic - pharmacology | Naphthoquinones - metabolism | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - metabolism | Proteins | Prevention | Care and treatment | Analysis | Plant metabolites | Protein binding | Cancer | Residues | Animal models | Bcl-2 protein | Pathogenesis | Leukemia | Kinases | Molecular docking | Anticancer properties | Plumbagin | Metabolites | Inhibition | Deoxyribonucleic acid--DNA | Binding | NF-κB protein | Medical research | AKT1 protein | Computer simulation | Molecular interactions | Stat3 protein | Simulation analysis | Cultures | Breast cancer | Signaling | Computer applications | Lymphomas | Mutation | Prostate cancer | Apoptosis | Tumors | Deoxyribonucleic acid | DNA
Journal Article
Emergency Medicine Journal, ISSN 1472-0205, 01/2013, Volume 30, Issue 1, pp. 81 - 83
A short-cut review was carried out to establish whether patients who had been successfully cardioverted after presenting to the emergency department with acute... 
Care and treatment | Research | Atrial fibrillation | Patient outcomes
Journal Article
Journal Article
Annals of Saudi Medicine, ISSN 0256-4947, 03/2017, Volume 37, Issue 2, pp. 148 - 153
BACKGROUND: Primary microcephaly (MCPH) is a rare developmental defect characterized by impaired cognitive functions, retarded neurodevelopment and reduced... 
MEDICINE, GENERAL & INTERNAL | CENTROSOMAL PROTEIN | KINASE | Microcephaly - genetics | Cross-Sectional Studies | Humans | Male | Mutation, Missense | Nerve Tissue Proteins - genetics | Intellectual Disability - genetics | Saudi Arabia | Young Adult | Exome - genetics | Female | Consanguinity | Child | Amino Acid Substitution | Microcephaly | Genes | Mutation | Original
Journal Article
世界胃肠病学杂志:英文版(电子版), ISSN 1007-9327, 2014, Volume 20, Issue 35, pp. 12462 - 12472
Chronic active hepatitis(CAH) is acknowledged as an imperative risk factor for the development of liver injury and hepatocellular carcinoma.The histological... 
Hepatitis | B | Hepa | virus | geno-type | Interferon regulatory factor 7 | Interleukin-1 receptor-associated kinase 4 | Hepatitis B virus genotype | TNF receptorassociated factor 3 | Peripheral blood mononuclear cells | Hepatocellular carcinoma | Hepatitis B virus | Ground squirrel hepatitis virus | Woodchuck hepatitis virus | X PROTEIN HBX | IMMUNE-RESPONSE | OXIDATIVE STRESS | ENDOPLASMIC-RETICULUM STRESS | NATURAL-HISTORY | TRANSACTIVATOR PROTEIN | HEPATOCELLULAR-CARCINOMA DEVELOPMENT | SURFACE-ANTIGEN | GASTROENTEROLOGY & HEPATOLOGY | TNF receptor-associated factor 3 | NF-KAPPA-B | UP-REGULATION | Liver - virology | Liver - pathology | Hepatitis B virus - pathogenicity | Humans | Hepatitis B, Chronic - diagnosis | Viral Proteins - metabolism | Inflammation Mediators - metabolism | Liver Cirrhosis - metabolism | Biomarkers, Tumor - metabolism | Liver Neoplasms - virology | Liver Cirrhosis - diagnosis | Signal Transduction | Carcinoma, Hepatocellular - diagnosis | Viral Proteins - genetics | Genotype | Carcinoma, Hepatocellular - virology | Hepatitis B, Chronic - virology | Host-Pathogen Interactions | Animals | Hepatitis B, Chronic - complications | Liver Cirrhosis - virology | Liver Neoplasms - diagnosis | Hepatitis B virus - genetics | Liver Neoplasms - metabolism | Hepatitis B virus - metabolism | Carcinoma, Hepatocellular - metabolism | Topic Highlight
Journal Article
BMC genomics, ISSN 1471-2164, 04/2017, Volume 18, Issue 1, pp. 281 - 1
This article [1] unfortunately published with an author deleted in the author list. The correct author list is presented above. The author list was previously... 
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0119765
The S100A8 and epidermal growth factor receptor (EGFR) proteins are proto-oncogenes that are strongly expressed in a number of cancer types. EGFR promotes... 
GROWTH-FACTOR RECEPTOR | OVEREXPRESSION | THERAPY | MULTIDISCIPLINARY SCIENCES | CARCINOMAS | AKT PATHWAY | PROTEINS | EXPRESSION | IN-SITU | DISCOVERY | PROGRESSION | Receptor, Epidermal Growth Factor - genetics | Kidney Neoplasms - genetics | Receptor, Epidermal Growth Factor - biosynthesis | Humans | Middle Aged | Protein Conformation - drug effects | Male | Staurosporine - analogs & derivatives | Calgranulin A - genetics | Molecular Targeted Therapy | Drug Discovery | Receptor, Epidermal Growth Factor - chemistry | Calgranulin A - chemistry | Protein Kinase Inhibitors - administration & dosage | Calgranulin A - biosynthesis | Signal Transduction - drug effects | Female | Kidney Neoplasms - pathology | Cell Proliferation - drug effects | Molecular Docking Simulation | Gene Expression Regulation, Neoplastic - drug effects | Kidney Neoplasms - drug therapy | Drug Resistance, Neoplasm - drug effects | Staurosporine - administration & dosage | Oncology, Experimental | Development and progression | Genetic transcription | Research | Antineoplastic agents | Cell differentiation | Proteins | Antimitotic agents | Ionizing radiation | Analysis | Kidney cancer | Health aspects | Cancer | Drugs | Profiling | Transcription | Leukocyte migration | Genes | Lung cancer | Differentiation (biology) | Cytology | Metastasis | Kinases | DNA repair | Cancer therapies | Molecular docking | Signal transduction | Cell growth | Epidermal growth factor | Antitumor agents | Pathways | Extravasation | Atherosclerosis | Cell cycle | Deoxyribonucleic acid--DNA | Medical research | Cell survival | Epidermal growth factor receptors | Research & development--R&D | Interleukin 12 | Inflammation | Gene expression | Survival | Medicine | White blood cells | Pathology | Signaling | Hospitals | Molecular modelling | Inhibitors | Arteriosclerosis | Biomarkers | Notch protein | Mutation | Cell migration | Tumors | Proto-oncogenes | Research & development | R&D | Deoxyribonucleic acid | DNA
Journal Article
BMC Medical Genomics, ISSN 1755-8794, 01/2015, Volume 8, Issue S1, pp. 1 - 11
Autosomal recessive primary microcephaly (MCPH) is a neurodevelopmental disorder that is characterised by microcephaly present at birth and non-progressive... 
ASPM MUTATIONS | PAKISTANI FAMILY | ABNORMAL SPINDLE PROTEIN | DNA-DAMAGE RESPONSE | GENETICS & HEREDITY | MITOTIC SPINDLE | CHROMOSOME CONDENSATION | BRAIN SIZE | SECKEL SYNDROME | PROTEIN-TRUNCATING MUTATIONS | CENTROSOMAL PROTEIN | Animals | Microcephaly - genetics | Mutation | Microcephaly - epidemiology | Saudi Arabia - epidemiology | Humans
Journal Article
Journal Article