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Angewandte Chemie - International Edition, ISSN 1433-7851, 11/2010, Volume 49, Issue 46, pp. 8649 - 8652
Journal Article
Nature Materials, ISSN 1476-1122, 11/2013, Volume 12, Issue 11, pp. 958 - 962
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2019, Volume 116, Issue 22, pp. 10674 - 10680
Cancer-associated fibroblasts (CAFs) can either suppress or support T lymphocyte activity, suggesting that CAFs may be reprogrammable to an immunosupportive... 
Pressure effects | Breast cancer | Lymphocytes T | Immunity | Hypotension | Metastases | Anticancer properties | Organic chemistry | Immunosuppression | Immune checkpoint | Lymphocytes | Breaking down | Immunotherapy | Angiotensin | pH | Fibroblasts | Antitumor activity | Blood pressure | Polymers | Cancer | Tumors | Biological Sciences | Physical Sciences | drug delivery | tumor microenvironment | PNAS Plus | cancer immunotherapy
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 7, pp. 2909 - 2914
The dense collagen network in tumors significantly reduces the penetration and efficacy of nanotherapeutics. We tested whether losartan—a clinically approved... 
Nanoparticles | Receptors | Medical treatment | Collagens | Antineoplastics | Viruses | Dosage | Pancreatic neoplasms | Tumors | Cancer | Thrombospondin-1 | Drug delivery | Transport | Transforming growth factor β | Matrix modifier | INTERSTITIAL FLUID PRESSURE | SOLID TUMORS | transforming growth factor beta | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | drug delivery | transport | BLOOD-FLOW | ANGIOTENSIN | CONVERTING-ENZYME-INHIBITORS | GROWTH-FACTOR-BETA | MOUSE MODEL | TYPE-1 RECEPTOR BLOCKADE | thrombospondin-1 | RENAL INJURY | matrix modifier | Immunohistochemistry | Skin Neoplasms - drug therapy | Fluorescence Recovery After Photobleaching | Humans | DNA Primers - genetics | Dose-Response Relationship, Drug | Pancreatic Neoplasms - drug therapy | Doxorubicin - analogs & derivatives | Polymerase Chain Reaction | Female | Collagen - biosynthesis | Losartan - pharmacokinetics | Doxorubicin - administration & dosage | Carcinoma - drug therapy | Nanotechnology - methods | Losartan - pharmacology | Mice, SCID | Breast Neoplasms - drug therapy | Polyethylene Glycols - administration & dosage | Oncolytic Virotherapy - methods | Simplexvirus | Animals | Analysis of Variance | Mice | Drug Delivery Systems - methods | Drugs | Care and treatment | Drug delivery systems | Medical technology | Research | Properties | Vehicles | Medical laboratory technology | Collagen | Losartan | Nanotechnology | Biological Sciences | Physical Sciences | transforming growth factor β
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2011, Volume 50, Issue 48, pp. 11417 - 11420
Shape dependent: Fluorescent quantum‐dot‐based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios... 
cancer | microscopy | luminescence | nanoparticles | imaging agents | PARTICLES | SEEDED GROWTH | XENOGRAFT | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | TRANSPORT | MICROENVIRONMENT | IMPROVES | EXTRACELLULAR-MATRIX | DIFFUSION | LIPOSOMES | Neoplasms - metabolism | Animals | Nanoparticles - chemistry | Metal Nanoparticles - chemistry | Nanomedicine - methods | Nanospheres - chemistry | Mice | Luminescent Measurements
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 6, pp. 2426 - 2431
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 2516
Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial... 
INTERSTITIAL FLUID PRESSURE | BREAST-CANCER | GROWTH-FACTOR-BETA | PANCREATIC STELLATE CELLS | TGF-BETA | AORTIC-ANEURYSM | SOLID STRESS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | GENE-EXPRESSION | II TYPE-2 RECEPTOR
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2012, Volume 109, Issue 38, pp. 15101 - 15108
Journal Article