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Cellular and Molecular Life Sciences, ISSN 1420-682X, 2019, Volume 76, Issue 10, pp. 1947 - 1966
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 9223 - 15
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 03/2015, Volume 104, Issue 3, pp. 1187 - 1196
The objective of this study is to develop and compare several Sorafenib-loaded biocompatible nanoparticle models in order to optimize drug delivery and tumor... 
nanotechnology | drug transport | chitosan | liposomes | cancer chemotherapy | poly (lactic/glycolic) acid (PLGA) | Drug transport | Cancer chemotherapy | Chitosan | Liposomes | Poly (lactic/glycolic) acid (PLGA) | Nanotechnology | CHEMISTRY, MEDICINAL | DRUG-DELIVERY | GLYCOL | CHEMISTRY, MULTIDISCIPLINARY | poly (lactic | glycolic) acid (PLGA | PHARMACOLOGY & PHARMACY | CYTOTOXICITY | EFFICIENCY | Niacinamide - analogs & derivatives | Humans | Drug Carriers | Dose-Response Relationship, Drug | Nanoparticles | Niacinamide - chemistry | Phenylurea Compounds - chemistry | 1,2-Dipalmitoylphosphatidylcholine - analogs & derivatives | 1,2-Dipalmitoylphosphatidylcholine - chemistry | Antineoplastic Agents - pharmacology | Carcinoma, Renal Cell - drug therapy | Lactic Acid - chemistry | Carcinoma, Renal Cell - pathology | Solubility | Technology, Pharmaceutical - methods | Chemistry, Pharmaceutical | Chitosan - chemistry | Polyglycolic Acid - chemistry | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Kidney Neoplasms - pathology | Phenylurea Compounds - pharmacology | Kinetics | Niacinamide - pharmacology | Kidney Neoplasms - drug therapy | Antimitotic agents | Drugs | Drug delivery systems | Chemotherapy | Carcinoma, Renal cell | Drug therapy | Comparative analysis | Antineoplastic agents | Vehicles | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0141655 - e0141655
HCV replication in persistently infected cell culture remains resistant to IFN-α/RBV combination treatment, whereas IFN-λ1 induces viral clearance. The... 
Interferon-alpha - pharmacology | Phosphorylation | MicroRNAs - antagonists & inhibitors | Humans | Hepacivirus - genetics | MicroRNAs - metabolism | Hepatocytes - metabolism | Hepacivirus - metabolism | Janus Kinase 1 - metabolism | RNA, Viral - antagonists & inhibitors | Janus Kinase 1 - genetics | Interleukins - pharmacology | Hepatocytes - drug effects | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Hepacivirus - drug effects | Hepatocyte Nuclear Factor 4 - metabolism | Virus Replication - drug effects | Antiviral Agents - pharmacology | Signal Transduction | RNA, Viral - biosynthesis | Gene Expression Regulation | Hepatocyte Nuclear Factor 4 - genetics | Host-Pathogen Interactions | Feedback, Physiological | STAT2 Transcription Factor - genetics | Cell Line, Tumor | Hepatocytes - virology | MicroRNAs - genetics | STAT2 Transcription Factor - metabolism | Ribavirin - pharmacology | Cell culture | Flow cytometry | Transcription | Laboratories | Hepatocellular carcinoma | Defense mechanisms | Infections | Activation | Feedback loops | Kinases | Proteins | Liver cancer | Genotype & phenotype | Signal transduction | Hepatitis | Feedback circuits | Feedback | Rodents | Hepatology | Gastroenterology | Antiviral activity | Hepatocyte nuclear factor 4 | Liver diseases | Cytokines | Stat3 protein | MiRNA | Inflammation | Gene expression | Ribonucleic acid--RNA | Medicine | Polymerase chain reaction | Pathology | Cytometry | Signaling | MicroRNAs | Cell lines | Replication | Interferon | Liver cirrhosis | Viral infections | Index Medicus | RNA | Ribonucleic acid
Journal Article
Seminars in Cancer Biology, ISSN 1044-579X, 06/2019, Volume 56, p. 12
The inhibitory kappa B kinases (IKKs) and IKK related kinases are crucial regulators of the pro-inflammatory transcription factor, nuclear factor kappa B... 
Antimitotic agents | Chemotherapy | Oncology, Experimental | Colorectal cancer | Research | Lung cancer, Non-small cell | Antineoplastic agents | Mitogens | Health aspects | Protein kinases | Protein-protein interactions | Cancer
Journal Article
Seminars in Cancer Biology, ISSN 1044-579X, 06/2019, Volume 56, pp. 12 - 24
The inhibitory kappa B kinases (IKKs) and IKK related kinases are crucial regulators of the pro-inflammatory transcription factor, nuclear factor kappa B... 
IKK related kinase | Cancer therapy | Inhibitory kappa B kinase | IKK inhibitor | Nuclear factor kappa B | PROTEASOME INHIBITION | ANTITUMOR-ACTIVITY | SALIVARY-GLAND TUMORS | EPITHELIAL-MESENCHYMAL TRANSITION | CELL LUNG-CANCER | BREAST-CANCER | B-ALPHA KINASE | IKK-RELATED KINASES | ONCOLOGY | GENE-EXPRESSION | TRANSCRIPTION FACTOR
Journal Article
Seminars in Cancer Biology, ISSN 1044-579X, 10/2018, Volume 52, Issue Pt 2, pp. 53 - 65
Neuroblastoma is the most common pediatric solid tumor of neural crest origin. The current treatment options for neuroblastoma produce severe side effects.... 
PD-L1 | Non-coding RNAs | Immuno-therapy | Inflammation | Neuroblastoma | SOLID TUMORS | CANCER-RELATED INFLAMMATION | MESENCHYMAL STEM-CELLS | STANDARDIZED METHOD | TUMOR-INFILTRATING LYMPHOCYTES | INDUCED EXPRESSION | ONCOLOGY | SIGNALING PATHWAY | POOR-PROGNOSIS | N-MYC | ULTRACONSERVED REGIONS | Immuno-Therapy | non-coding RNAs
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 10/2018, Volume 188, Issue 10, pp. 2339 - 2355
Liver cirrhosis is an independent risk factor for hepatocellular carcinoma (HCC). The mechanisms that contribute to HCC development in the cirrhotic... 
OXIDATIVE STRESS | IN-VITRO | UNFOLDED PROTEIN RESPONSE | CARCINOGENESIS | PATHWAY | ER STRESS | ACTIVATES STAT-3 | PERK | PATHOLOGY | HUMAN HEPATOCELLULAR-CARCINOMA | CANCER
Journal Article