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Advances in Pharmacology, ISSN 1054-3589, 01/2017, Volume 79, pp. 1 - 34
GABA receptors (GABA Rs) are a class of ligand-gated ion channels with high physiological and therapeutic significance. In the brain, these pentameric... 
receptor | Subunit stoichiometry | GABA | Pharmacology | Anesthetics | Cys-loop receptors | Ion channel | Arrangement | Benzodiazepines
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2018, Volume 24, Issue 17, pp. 1839 - 1844
GABAA receptors (GABAARs) are members of the Cys-loop ligand-gated ion channel (LGIC) superfamily, which includes nicotinic acetylcholine, glycine, and... 
Zolpidem | Stoichiometry | GABAa receptors | Subunit | Subtype | Benzodiazepines
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 03/2015, Volume 112, Issue 10, pp. 3104 - 3109
Even moderate doses of alcohol cause considerable impairment of motor coordination, an effect that substantially involves potentiation of GABAergic activity at... 
Electrophysiology | GABA | Alcohol | Motor impairment | Oxytocin | Injections, Spinal | Oxytocin - administration & dosage | Ethanol - pharmacology | Animals | Oxytocin - pharmacology | Rats, Wistar | Receptors, GABA-A - drug effects | Motor Activity - drug effects | Rats | Male | alcohol | Biological Sciences | oxytocin | electrophysiology | motor impairment
Journal Article
The Journal of general physiology, ISSN 0022-1295, 06/2019, Volume 151, Issue 6, pp. 798 - 819
γ-aminobutyric acid type A receptors (GABA Rs), the major inhibitory neurotransmitter receptors in the mammalian central nervous system, are arguably the most... 
Stoichiometry | γ-Aminobutyric acid | γ-Aminobutyric acid A receptors | Neurotransmitter receptors | Central nervous system | 514
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 05/2011, Volume 163, Issue 2, pp. 234 - 245
Journal Article
Molecules, ISSN 1420-3049, 01/2019, Volume 24, Issue 3, p. 446
Neurodegenerative disorders, including Alzheimer’s disease, belong to the group of the most difficult and challenging conditions with very limited treatment... 
AChE | docking | multi modal | dual mode of action | lead identification | virtual screening | nAChR | acetylcholinesterase | neurodegenerative disorders | nicotinic acetylcholine receptor
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0161154
The α4β2 nicotinic acetylcholine receptor (nAChR) is the most abundant subtype in the brain and exists in two functional stoichiometries: (α4)3(β2)2 and... 
Brain | Stoichiometry | Neurosciences | Electrophysiology | Activation | Benzodiazepines | Receptors | Properties (attributes) | Pharmacy | Ligands | Acetylcholine receptors (nicotinic) | Receptor mechanisms | Binding sites
Journal Article
Tetrahedron, ISSN 0040-4020, 03/2018, Volume 74, Issue 12, pp. 1245 - 1252
Four histrionicotoxin analogues were prepared in an efficient manner utilizing a nitrone dipolar cycloaddition reaction as the key step in forming tricyclic... 
1,3-Dipolar cycloaddition | Antagonist | Histrionicotoxin | Poison arrow frog toxin | Nicotinic acetylcholine receptor
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 08/2017, Volume 23, Issue 45, pp. 10848 - 10852
Halogenated analogues of the neurotoxic alkaloid muscimol were prepared with fluorine, iodine or trifluoromethyl at the 4 position of the isoxazole ring... 
trifluoromethyl | iodination | muscimol | gaba receptors fluorination | gaba agonists | REAGENT | METHYL FLUOROSULFONYLDIFLUOROACETATE | CHEMISTRY, MULTIDISCIPLINARY | F-18 | IODIDES | POSITRON-EMISSION-TOMOGRAPHY | OOCYTES | ARYL | RECEPTORS | GABA | Analysis | Fluorides | Receptors | Neurotoxicity | γ-Aminobutyric acid | γ-Aminobutyric acid A receptors | Fluorine | Analogue | Halogenated | Muscimol | Iodine | Index Medicus
Journal Article
Evidence-based Complementary and Alternative Medicine, ISSN 1741-427X, 2016, Volume 2016, p. 1215393
Artemisia indica, also known as "Mugwort," has been widely used in traditional medicines. However, few studies have investigated the effects of nonvolatile... 
MECHANISMS | STREPTOZOTOCIN | PHYTOCHEMICAL ANALYSIS | INTEGRATIVE & COMPLEMENTARY MEDICINE | Flumazenil | Anticonvulsants | Antidepressants | Depression, Mental | GABA | Seizures (Medicine) | Antianxiety agents | Studies | Flavonoids | Nuclear magnetic resonance--NMR | Pharmacy | Chemicals | Chromatography
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 03/2016, Volume 103, pp. 98 - 108
Journal Article