X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry (27) 27
metallurgy (27) 27
beer (21) 21
biochemistry (21) 21
enzymology (21) 21
index medicus (21) 21
microbiology (21) 21
mutation or genetic engineering (21) 21
spirits (21) 21
vinegar (21) 21
wine (21) 21
human necessities (19) 19
hygiene (19) 19
medical or veterinary science (19) 19
preparations for medical, dental, or toilet purposes (19) 19
investigating or analysing materials by determining theirchemical or physical properties (16) 16
measuring (16) 16
physics (16) 16
testing (16) 16
animals (14) 14
compositions or test papers therefor (12) 12
condition-responsive control in microbiological orenzymological processes (12) 12
measuring or testing processes involving enzymes, nucleicacids or microorganisms (12) 12
neurons (12) 12
processes of preparing such compositions (12) 12
article (11) 11
humans (11) 11
organic chemistry (11) 11
parkinson's disease (11) 11
compositions thereof (10) 10
culture media (10) 10
microorganisms or enzymes (10) 10
propagating, preserving or maintaining microorganisms (10) 10
rats (10) 10
agriculture (9) 9
animal husbandry (9) 9
care of birds, fishes, insects (9) 9
fishing (9) 9
forestry (9) 9
hunting (9) 9
nervous system (9) 9
new breeds of animals (9) 9
parkinsons-disease (9) 9
rearing or breeding animals, not otherwise provided for (9) 9
trapping (9) 9
physiological aspects (8) 8
specific therapeutic activity of chemical compounds ormedicinal preparations (8) 8
toxicity (8) 8
cell biology (7) 7
mice (7) 7
peptides (7) 7
alpha-synuclein - metabolism (6) 6
female (6) 6
multidisciplinary sciences (6) 6
neurons - metabolism (6) 6
parkinson’s disease (6) 6
yeast (6) 6
alpha-synuclein (5) 5
alpha-synuclein - genetics (5) 5
biochemistry & molecular biology (5) 5
health aspects (5) 5
heterocyclic compounds (5) 5
neurodegeneration (5) 5
neurosciences (5) 5
parkinson disease - metabolism (5) 5
protein (5) 5
alzheimers-disease (4) 4
cells (4) 4
cells, cultured (4) 4
neurons - drug effects (4) 4
parkinson disease - genetics (4) 4
rats, sprague-dawley (4) 4
research (4) 4
stem cells (4) 4
biological sciences (3) 3
cell line (3) 3
degeneration (3) 3
disease models, animal (3) 3
dopamine - physiology (3) 3
gene expression profiling (3) 3
gene-expression (3) 3
genetic aspects (3) 3
genetics (3) 3
mice, transgenic (3) 3
model (3) 3
models, neurological (3) 3
mutation (3) 3
nervous system diseases (3) 3
neurons - pathology (3) 3
parkinsons disease (3) 3
pharmacology (3) 3
phosphorylation (3) 3
proteins (3) 3
risk (3) 3
risk factors (3) 3
saccharomyces cerevisiae - genetics (3) 3
saccharomyces cerevisiae proteins - genetics (3) 3
saccharomyces-cerevisiae (3) 3
vesicle trafficking (3) 3
yeasts (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Reports, ISSN 2211-1247, 12/2018, Volume 25, Issue 10, pp. 2742 - 2754.e31
The lack of disease-modifying treatments for neurodegenerative disease stems in part from our rudimentary understanding of disease mechanisms and the paucity... 
stearoyl-CoA desaturase | fatty acid desaturation | chemical genetics | target identification | α-synuclein | Parkinson’s disease | phenotypic drug screen | vesicle trafficking | Parkinson's disease | PARKINSON | MUTATION | GENE-EXPRESSION | TRAFFICKING | TARGETS | FATTY-ACIDS | TOXICITY | MODEL | IDENTIFICATION | OLIGOMERS | CELL BIOLOGY
Journal Article
Journal Article
Movement Disorders, ISSN 0885-3185, 09/2014, Volume 29, Issue 10, pp. 1231 - 1240
Journal Article
Science, ISSN 0036-8075, 11/2013, Volume 342, Issue 6161, pp. 979 - 983
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1241 - 1245
Aβ (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory... 
Oligomers | Yeasts | Endocytosis | Receptors | Neurons | Secretion | RESEARCH ARTICLES | Predisposing factors | Cell membranes | Alzheimers disease | Genetic screening | COMMON VARIANTS | CELLS | IDENTIFIES VARIANTS | MEMBRANE | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM | ALPHA-SYNUCLEIN | SACCHAROMYCES-CEREVISIAE | PEPTIDE | OLIGOMERS | GENOME-WIDE ASSOCIATION | Genetic Testing | Saccharomyces cerevisiae - genetics | Humans | Protein Multimerization | Secretory Pathway | Glutamates - metabolism | Saccharomyces cerevisiae - metabolism | Monomeric Clathrin Assembly Proteins - genetics | Amyloid beta-Peptides - genetics | Monomeric Clathrin Assembly Proteins - metabolism | Amyloid beta-Peptides - metabolism | Neurons - physiology | Cell Membrane - metabolism | Peptide Fragments - genetics | Peptide Fragments - metabolism | Caenorhabditis elegans - metabolism | Disease Susceptibility | Genetic Association Studies | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Risk Factors | Cells, Cultured | Rats | Saccharomyces cerevisiae Proteins - genetics | Clathrin - metabolism | Protein Transport | Saccharomyces cerevisiae - cytology | Peptide Fragments - chemistry | Animals | Caenorhabditis elegans - cytology | Alzheimer Disease - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Cytoskeleton - metabolism | Amyloid beta-Peptides - chemistry | Alzheimer Disease - genetics | Saccharomyces cerevisiae - growth & development | Index Medicus | Basic Medicine | Other Basic Medicine | peptide | membrane | Medical and Health Sciences | Medicin och hälsovetenskap | oligomers | alpha-synuclein | saccharomyces cerevisiae | cells | identifies variants | Medicinska och farmaceutiska grundvetenskaper | Annan medicinsk grundvetenskap | genome-wide association | endoplasmic reticulum | common variants
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 34, pp. 12281 - 12281
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 12/2017, Volume 114, Issue 52, p. E11313
Journal Article
Movement Disorders, ISSN 0885-3185, 09/2014, Volume 29, Issue 10, pp. 1231 - 1240
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2009, Volume 106, Issue 52, pp. 22474 - 22479
In Parkinson's disease (PD), dopaminergic (DA) neurons in the substantia nigra (SN, A9) are particularly vulnerable, compared to adjacent DA neurons within the... 
Protein isoforms | Neurotransmitters | Nervous system diseases | Disease models | Neurons | Parkinson disease | Rats | Lesions | Synapses | PC12 cells | Differential vulnerability | Synaptic vesicles | RAB | Parkinson's disease | OXIDATIVE STRESS | PROTEIN | EXOCYTOSIS | differential vulnerability | MULTIDISCIPLINARY SCIENCES | VULNERABILITY | NEURODEGENERATION | SYNAPSES | GENE-EXPRESSION | NEURONS | synaptic vesicles | RABPHILIN | PARKINSONS-DISEASE | Synaptic Vesicles - metabolism | Humans | Gene Expression Profiling | Presynaptic Terminals - ultrastructure | Substantia Nigra - metabolism | RNA, Messenger - metabolism | Corpus Striatum - metabolism | Parkinsonian Disorders - metabolism | rab3 GTP-Binding Proteins - metabolism | Female | Parkinsonian Disorders - genetics | Parkinson Disease - metabolism | Dopamine - metabolism | Cell Line | Levodopa - pharmacology | Gene Expression | Parkinson Disease - pathology | 3,4-Dihydroxyphenylacetic Acid - metabolism | Presynaptic Terminals - drug effects | RNA, Messenger - genetics | Parkinson Disease - genetics | Rats, Sprague-Dawley | rab3 GTP-Binding Proteins - genetics | Oxidopamine - toxicity | Animals | Parkinsonian Disorders - pathology | Ventral Tegmental Area - metabolism | Corpus Striatum - drug effects | Presynaptic Terminals - metabolism | Models, Neurological | In Vitro Techniques | Leupeptins - toxicity | Dopamine | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression | Risk factors | Proteins | Proteases | Rodents | Parkinsons disease | Comparative analysis | Cells | Index Medicus | Biological Sciences
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2014, Volume 111, Issue 34, pp. E3544 - E3552
  Calcineurin (CN) is a highly conserved Ca^sup 2+^ -calmodulin (CaM)-dependent phosphatase that senses Ca^sup 2+^ concentrations and transduces that... 
Homeostasis | Phosphatase | Toxicity
Journal Article
Science, ISSN 0036-8075, 11/2013, Volume 342, Issue 6161, pp. 979 - 983
[alpha]-Synuclein ([alpha]-syn) is a small lipid-binding protein implicated in several neurodegenerative diseases, including Parkinson's disease, whose... 
Physiological aspects | Research | Binding proteins | Health aspects | Neurophysiology | Toxicity | Neurons | Yeast
Journal Article
Science, ISSN 0036-8075, 11/2013, Volume 342, Issue 6161, pp. 983 - 987
The induced pluripotent stern (iPS) cell field holds promise for in vitro disease modeling. However, identifying innate cellular pathologies, particularly for... 
Physiological aspects | Parkinson's disease | Research | Health aspects | Stem cells | Neurophysiology | Toxicity | Neurons | Patients | Parkinsons disease
Journal Article