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Journal of Pathology, ISSN 0022-3417, 07/2016, Volume 239, Issue 3, p. 344
Persistent or dysregulated IL-13 responses are key drivers of fibrosis in multiple organ systems, and this identifies this cytokine as an important therapeutic... 
Interleukins | RNA | Analysis | Collagen | Liver | Fibrosis | Monoclonal antibodies | Development and progression | Interferon | Inflammation | Biological response modifiers | Cytokines | Rodents | Genes
Journal Article
Experimental Models of Schistosoma mansoni   Infection, 12/2002
Experimental models of Schistosoma mansoni   infections in mammals have contributed greatly to our understanding of the pathology and pathogenesis of... 
Schistosoma mansoni   - experimental models - schistosomiasis
Journal
Role of cytokines in the formation and downregulation of hepatic circumoval granulomas and hepatic fibrosis in Schistosoma mansoni-infected mice, 12/1998
Schistosoma mansoni infections are associated with a strong Th2 cytokine response. Treatment of mice with IL-12 or anti-IL-2 or anti-IL-4 before i.v. injection... 
schistosomiasis - granulomas - cytokines - immunoregulation - hepatic fibrosis - type 2 delayed hypersensitivity
Journal
Role of cytokines in the formation and downregulation of hepatic circumoval granulomas and hepatic fibrosis in Schistosoma mansoni-infected mice, 12/1998
Schistosoma mansoni infections are associated with a strong Th2 cytokine response. Treatment of mice with IL-12 or anti-IL-2 or anti-IL-4 before i.v. injection... 
schistosomiasis - granulomas - cytokines - immunoregulation - hepatic fibrosis - type 2 delayed hypersensitivity
Journal
PLoS Pathogens, ISSN 1553-7366, 04/2009, Volume 5, Issue 4, pp. e1000371 - e1000371
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 03/2010, Volume 207, Issue 3, pp. 535 - 552
Idiopathic pulmonary fibrosis (IPF) is a destructive inflammatory disease with limited therapeutic options. To better understand the inflammatory responses... 
MEDICINE, RESEARCH & EXPERIMENTAL | INTRATRACHEAL BLEOMYCIN | CELL-MEDIATED PATHOLOGY | TGF-BETA | INTERFERON-GAMMA | AUTOIMMUNE INFLAMMATION | IN-VIVO | IL-17-PRODUCING T-CELLS | INDUCED LUNG INJURY | IMMUNOLOGY | NF-KAPPA-B | NEUTROPHIL RECRUITMENT
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2016, Volume 17, Issue 5, pp. 538 - 544
Acidic mammalian chitinase (AMCase) is known to be induced by allergens and helminths, yet its role in immunity is unclear. Using AMCase-deficient mice, we... 
Strongylida Infections - metabolism | Hypersensitivity - immunology | Interleukin-13 - immunology | Hormones, Ectopic - metabolism | Chitinases - metabolism | Chloride Channels - genetics | Nippostrongylus - immunology | Nematospiroides dubius - immunology | Chitinases - genetics | Gastrointestinal Tract - immunology | Lectins - metabolism | Interleukin-13 - genetics | Flow Cytometry | Hypersensitivity - metabolism | Strongylida Infections - parasitology | Strongylida Infections - immunology | Gene Expression - immunology | Hypersensitivity - genetics | Lung - metabolism | beta-N-Acetylhexosaminidases - genetics | Nematospiroides dubius - physiology | Lung - pathology | Lectins - immunology | beta-N-Acetylhexosaminidases - metabolism | Mice, Inbred C57BL | Immunity - immunology | Host-Parasite Interactions - immunology | beta-N-Acetylhexosaminidases - immunology | Chloride Channels - immunology | Interleukin-13 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Gastrointestinal Tract - metabolism | Mice, Knockout | Chloride Channels - metabolism | Animals | Nippostrongylus - physiology | Hormones, Ectopic - immunology | Hormones, Ectopic - genetics | Chitinases - immunology | Lectins - genetics | Immunity - genetics | Gastrointestinal Tract - parasitology | Lung - immunology | Microscopy, Fluorescence | Roundworm infections | Enzymes | Immune response | Gastrointestinal diseases | Development and progression | Hydrolases | Genetic aspects | Properties | Index Medicus
Journal Article
PLoS pathogens, ISSN 1553-7366, 09/2014, Volume 10, Issue 9, pp. e1004372 - e1004372
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2009, Volume 5, Issue 4, pp. e1000393 - e1000393
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2011, Volume 7, Issue 8, pp. e1002171 - e1002171
Despite effective chemotherapy to treat schistosome infections, re-infection rates are extremely high. Resistance to reinfection can develop, however it... 
LEISHMANIA-MAJOR | T-HELPER-2 CYTOKINE RESPONSES | ANTISCHISTOSOMAL DRUGS | HAEMATOBIUM INFECTION | MICROBIOLOGY | MURINE SCHISTOSOMIASIS | OCCUPATIONALLY EXPOSED ADULTS | GRANULOMA-FORMATION | VIROLOGY | IMMUNE-RESPONSES | IN-VIVO | REGULATORY T-CELLS | PARASITOLOGY | Schistosomiasis mansoni - genetics | Eosinophils - metabolism | Immunoglobulin G - blood | Schistosomiasis mansoni - immunology | Interleukin-10 - blood | Antibodies, Helminth - immunology | Th2 Cells - immunology | Schistosoma mansoni - metabolism | Schistosomiasis mansoni - drug therapy | Th1 Cells - immunology | Eosinophils - immunology | Immunoglobulin E - blood | Th1 Cells - metabolism | Signal Transduction - immunology | Immunoglobulin E - immunology | Th17 Cells - metabolism | Immunoglobulin G - immunology | Female | Antibodies, Helminth - blood | Praziquantel - pharmacology | Schistosomiasis mansoni - blood | Mice, Transgenic | Schistosoma mansoni - immunology | Signal Transduction - genetics | Th2 Cells - metabolism | Animals | Anthelmintics - pharmacology | Interleukin-10 - genetics | Th17 Cells - immunology | Mice | Interleukin-10 - immunology | Schistosomiasis | Interleukins | Physiological aspects | Antiparasitic agents | Diagnosis | Research | Health aspects | Risk factors | Infections | Immunology | Parasites | Rodents | Immune system | Index Medicus
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2016, Volume 8, Issue 337, pp. 337ra65 - 337ra65
Journal Article