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European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, pp. 438 - 457
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2017, Volume 138, p. 438
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.ejmech.2017.06.017 
Proteins | Antioxidants | Nervous system diseases | Synthesis | Adenosine kinase | Glycogen | Analysis | Drug discovery
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 11/2019, Volume 24, Issue 23, p. 4373
Tuberculosis (TB) is one of the top 10 causes of death worldwide. This scenario is further complicated by the insurgence of multidrug-resistant (MDR) and... 
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2017, Volume 127, pp. 859 - 873
Prion diseases are serious, not curable neurodegenerative disorders caused by the accumulation of the misfolded protein PrP that represents the pathological... 
Pharmacophore modeling | 3D-QSAR | Anti-Prion agents | Theranostic tools | Prion
Journal Article
Medicinal chemistry (Shariqah (United Arab Emirates)), ISSN 1573-4064, 2019, Volume 15, Issue 7, p. 755
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 859 - 873
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, p. 859
Prion diseases are serious, not curable neurodegenerative disorders caused by the accumulation of the misfolded protein PrP.sup.Sc that represents the... 
Prevention | Cellular proteins | Nervous system diseases | Analysis | Prion diseases | Chemical properties | Drug discovery | Permeability | Investigations | Protein binding | Fluorescence
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 859 - 873
Prion diseases are serious, not curable neurodegenerative disorders caused by the accumulation of the misfolded protein PrP that represents the pathological... 
3D-QSAR | Anti-Prion agents | Pharmacophore modeling | Theranostic tools | Prion | CHEMISTRY, MEDICINAL | PROTEIN | MECHANISM | IN-SILICO | 2-AMINOTHIAZOLES | DISCOVERY | POTENT | ACCURATE DOCKING | BIOLOGY | CREUTZFELDT-JAKOB-DISEASE | INHIBITORS | Index Medicus
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 07/2017, Volume 135, pp. 479 - 490
Journal Article
FRONTIERS IN CHEMISTRY, ISSN 2296-2646, 08/2019, Volume 7, p. 574
We describe herein the development and experimental validation of a computational protocol for optimizing a series of 3-hydroxy-pyran-4-one derivatives as HIV... 
3-hydroxy-pyran-4-one | in silico combinatorial library design | ASSAY | side chain hopping | DOCKING | HIV-1 integrase inhibitors (HIV-1 INIs) | hit compounds optimization | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | ZINC | REDUCTION | DYNAMICS | FORCE-FIELD | BINDING | Molecular dynamics | Usage | Care and treatment | Integrase inhibitors | HIV infection | HIV (Viruses) | Methods | Raltegravir
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 12/2018, Volume 59, Issue 51, pp. 4466 - 4470
We developed a Jocic-type protocol for the construction of the pyrrolonaphthoxazepine (PNOX) core. After an initial investigation based on the isolation of a... 
Jocic reaction | Antitumor agents | Pyrrolonaphthoxazepines | Aryl-alkyl ethers | SUBSTITUTION | ALPHA-AMINO | ENANTIOSELECTIVE SYNTHESIS | CHEMISTRY, ORGANIC | PYRROLOBENZOXAZEPINE | PYRROLO-1,5-BENZOXAZEPINE | TRICHLOROMETHYL KETONES | PRIMER GRIP REGION | BIOLOGICAL-ACTIVITY | INHIBITORS | DERIVATIVES | Organic acids | Apoptosis
Journal Article