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Human Pathology, ISSN 0046-8177, 09/2019, Volume 91, pp. 114 - 122
Mutations of the succinate dehydrogenase ( ) enzyme subunits commonly lead to a loss of function of the holoenzyme complex, and germline mutations lead to a... 
Fumarate hydratase | Succinate dehydrogenase | FH | 2SC | SDHA | SDHB | S-(2-succino)-cysteine | SUBTYPE | HEREDITARY LEIOMYOMATOSIS | PARAGANGLIOMA | PATHOLOGY | CANCER | GENE | MUTATION | PHEOCHROMOCYTOMAS | KIDNEY TUMORS | Dehydrogenases | Kidney cancer | Histology | Mutation | Patients | Cytoplasm | Age | Tumors
Journal Article
Genes and Development, ISSN 0890-9369, 06/2012, Volume 26, Issue 12, pp. 1326 - 1338
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2018, Volume 115, Issue 34, pp. E8027 - E8036
Activated T cells undergo metabolic reprogramming and effector-cell differentiation but the factors involved are unclear. Utilizing mice lacking DUSP6... 
Glycolysis | Follicular helper T cells | DUSP6 | IL-21 | T cell metabolism | ACTIVATION | follicular helper T cells | PROTEIN-KINASE PHOSPHATASE | MULTIDISCIPLINARY SCIENCES | glycolysis | IMMUNOGLOBULIN PRODUCTION | CXC CHEMOKINE RECEPTOR-5 | FOLLICULAR-HELPER-CELLS | GLUCOSE-METABOLISM | SIGNALING PATHWAY | GENERATION | DUAL-SPECIFICITY PHOSPHATASE | EXPRESSION | Dual Specificity Phosphatase 6 - genetics | MAP Kinase Kinase 4 - immunology | Mitochondria - immunology | Oxygen Consumption - physiology | Interleukins - metabolism | CD28 Antigens - metabolism | Glycolysis - physiology | Interleukins - genetics | MAP Kinase Kinase 4 - metabolism | CD28 Antigens - genetics | Mitochondria - genetics | Immunoglobulin G - immunology | T-Lymphocytes, Helper-Inducer - immunology | Interleukins - immunology | T-Lymphocytes, Helper-Inducer - cytology | Receptors, Antigen, T-Cell - immunology | p38 Mitogen-Activated Protein Kinases - metabolism | Cell Differentiation - physiology | T-Lymphocytes, Helper-Inducer - metabolism | Dual Specificity Phosphatase 6 - immunology | Receptors, Antigen, T-Cell - metabolism | p38 Mitogen-Activated Protein Kinases - genetics | CD28 Antigens - immunology | Mitochondria - metabolism | p38 Mitogen-Activated Protein Kinases - immunology | Antibody Formation - physiology | Mice, Knockout | Dual Specificity Phosphatase 6 - metabolism | Animals | MAP Kinase Kinase 4 - genetics | Signal Transduction - physiology | Mice | Receptors, Antigen, T-Cell - genetics | Immunoglobulin G - metabolism
Journal Article
by Zhang, WQ and Zhang, HH and Liu, SJ and Xia, FC and Kang, ZJ and Zhang, Y and Liu, YY and Xiao, H and Chen, L and Huang, CX and Shen, N and Xu, HJ and Li, FB
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 09/2019, Volume 116, Issue 37, pp. 18550 - 18560
Excessive self-reactive and inadequate affinity-matured antigen-specific antibody responses have been reported to coexist in lupus, with elusive cellular and... 
CYTIDINE DEAMINASE AID | autoantibody | CLASS SWITCH RECOMBINATION | SOMATIC HYPERMUTATION | MULTIDISCIPLINARY SCIENCES | ANTIGEN PRESENTATION | lupus | MyD88 | CD11c(+)T-bet(+) B cells | ECTOPIC LYMPHOID-TISSUE | germinal center selection | CLONAL SELECTION | ERYTHEMATOSUS PATIENTS | ANTIBODY-RESPONSES | AUTOIMMUNE-DISEASE | FOLLICULAR HELPER-CELLS
Journal Article
ACM Transactions on Design Automation of Electronic Systems (TODAES), ISSN 1084-4309, 07/2016, Volume 21, Issue 3, pp. 1 - 31
With the sharp increase of very large-scale integrated (VLSI) circuit density, we are faced with many knotty issues. Particularly in the routing phase of VLSI... 
router | VLSI design | Steiner tree | obstacle | Octilinear architecture | Router | Obstacle | COMPUTER SCIENCE, SOFTWARE ENGINEERING | COMPUTER SCIENCE, HARDWARE & ARCHITECTURE | ALGORITHM | FLUTE | Trees | Integrated circuits | Design engineering | Algorithms | Architecture | Very large scale integration | Strategy | Information centers
Journal Article
Nature Immunology, ISSN 1529-2908, 2014, Volume 15, Issue 7, pp. 597 - 599
The transcription factors Foxp1 and Foxo1 inhibit the differentiation of follicular helper T cells. On the other hand, the E3 ligase Itch targets Foxo1 for... 
CELLS | IMMUNOLOGY | FOXO TRANSCRIPTION FACTORS | ANTIBODY-RESPONSES
Journal Article
Human mutation, ISSN 1059-7794, 08/2019
Fumarate hydratase (FH) mutations underpin the autosomal recessive syndrome. FH deficiency and the autosomal dominant syndrome hereditary leiomyomatosis and... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2018, Volume 115, Issue 34, p. E8027
Few mechanisms are known that explain how transcription factors can adjust phenotypic outputs to accommodate differing environments. In Saccharomyces... 
Binding | Transcription factors | Yeast | Biological evolution | Differentiation (biology) | Amino acid sequence | Saccharomyces | Metabolism | Cell differentiation | Mutants | Mating | T-cell receptor | Immunology | Lymphocytes | Glycolysis | Mutation | Saccharomyces cerevisiae | Metabolic disorders | Deoxyribonucleic acid--DNA
Journal Article
FRONTIERS IN PHYSIOLOGY, ISSN 1664-042X, 03/2019, Volume 10, p. 280
Journal Article
Atherosclerosis, ISSN 0021-9150, 08/2019, Volume 287, pp. e253 - e253
Journal Article
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, ISSN 1476-7058, 08/2019, pp. 1 - 9
To explore the feasibility of applying smart-planes fetal heart (S-Planes FH) to 3D volumes to generate and display the outflow tract views (OFTVs) and... 
Journal Article
Journal of Physical Chemistry A, ISSN 1089-5639, 12/2015, Volume 119, Issue 50, pp. 12193 - 12208
Journal Article
CANCER DISCOVERY, ISSN 2159-8274, 10/2016, Volume 6, Issue 10, pp. 1182 - 1195
The existence, regulation, and functions of IL21(+) immune cells are poorly defined in human cancers. Here, we identified a subset of protumorigenic IL21(+)... 
ACTIVATED MONOCYTES | FOSTER IMMUNE PRIVILEGE | HEPATOCELLULAR-CARCINOMA | HUMAN DENDRITIC CELLS | ONCOLOGY | PERITUMORAL STROMA | FOLLICULAR HELPER-CELL | DIFFERENTIATION | PROMOTE | TUMOR MICROENVIRONMENT | DISEASE PROGRESSION
Journal Article
Journal of Physical Chemistry A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, ISSN 1089-5639, 12/2015, Volume 119, Issue 50, pp. 12193 - 12208
The FH sub(2) super(-) anion has a stable structure that resembles a configuration in the vicinity of the transition state for neutral reaction F + H sub(2)... 
Potential energy | Detachment | Anions | Simulation | Dynamics | Photodetachment | Photoelectrons | Spectra
Journal Article
by Hu, YJ and Zhang, HP and Zhu, B and Chen, HY and Ma, LH and Wang, Y
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 10/2018, Volume 22, Issue 19, pp. 6288 - 6293
OBJECTIVE: Cervical cancer is a common type in gynecologic malignant tumor that accounts for the leading morbidity only after breast cancer in female. This... 
Uterine epithelial cell stability FH test | CELLS | PHOTODYNAMIC THERAPY | PERFORMANCE | HYBRID CAPTURE 2 | CLINICIAN | HUMAN-PAPILLOMAVIRUS | Precancerous lesion | HPV | PHARMACOLOGY & PHARMACY | Diagnosis | RADIOTHERAPY | Cervical cancer
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2014, Volume 15, Issue 7, pp. 597 - 599
Journal Article
European review for medical and pharmacological sciences, ISSN 1128-3602, 10/2018, Volume 22, Issue 19, pp. 6288 - 6293
Journal Article
GENES & DEVELOPMENT, ISSN 0890-9369, 02/2015, Volume 29, Issue 4, pp. 409 - 425
It is now well established that the E and Id protein axis regulates multiple steps in lymphocyte development. However, it remains unknown how E and Id proteins... 
c-Myc/p19Arf | TUMOR SUPPRESSION | FOXO/mTORC1 pathway | tumor suppressor | DEVELOPMENTAL BIOLOGY | T-cell quiescence | Id proteins | NEGATIVE REGULATOR | CELL BIOLOGY | LOOP-HELIX PROTEIN | BURKITT-LYMPHOMA | GAMMA-DELTA | LYMPHOCYTE DEVELOPMENT | TRANSCRIPTION FACTOR FOXP1 | GENETICS & HEREDITY | THERAPEUTIC TARGETS | DIFFERENTIATION | LINEAGE | T-cell lymphoma
Journal Article
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