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devices or arrangements, the optical operation of which ismodified by changing the optical properties of the medium of thedevices or arrangements for the control of the intensity,colour, phase, polarisation or direction of light, e.g.switching, gating, modulating or demodulating (8) 8
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1. Full Text Integration of metabolomics and transcriptomics reveals short-chain chlorinated paraffin-induced hepatotoxicity in male Sprague-Dawley rat
by Geng, Ningbo and Ren, Xiaoqian and Gong, Yufeng and Zhang, Haijun and Wang, Feidi and Xing, Liguo and Cao, Rong and Xu, Jiazhi and Gao, Yuan and Giesy, John P and Chen, Jiping
Environment International, ISSN 0160-4120, 12/2019, Volume 133, pp. 105231 - 105231
Short-chain chlorinated paraffins (SCCPs) used in various industrial applications have been listed as new POPs. Previous studies based on high-dose exposures... 
Metabolomic | Energy metabolism | Transcriptomic | PPARα | SCCPs | Index Medicus
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2. Full Text Microbiota-specific Th17 cells: Yin and Yang in regulation of inflammatory bowel disease
by Wu, Wei and Chen, Feidi and Liu, Zhanju and Cong, Yingzi
Inflammatory Bowel Diseases, ISSN 1078-0998, 06/2016, Volume 22, Issue 6, pp. 1473 - 1482
Multiple mechanisms are involved in regulation of host response to microbiota to maintain the intestinal homeostasis. Th17 cells are enriched in the intestinal... 
microbiota | Th17 | IBD | AUTOIMMUNE INFLAMMATION | PATHOGENIC T(H)17 CELLS | ULCERATIVE-COLITIS | ACTIVE CROHNS-DISEASE | LAMINA PROPRIA | COLITIC C3H/HEJBIR MICE | HELPER T-CELLS | INTESTINAL INFLAMMATION | BACTERIAL-ANTIGENS | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Th17 Cells - physiology | Immunoglobulin A - metabolism | Humans | Inflammatory Bowel Diseases - immunology | Homeostasis | Inflammatory Bowel Diseases - physiopathology | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | Intestinal Mucosa - physiology | Interleukin-17 - metabolism | Animals | Intestinal Mucosa - immunology | Th17 Cells - immunology | Cell Transdifferentiation | Gastrointestinal Microbiome - immunology | Microbiota
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3. Full Text Deep‐Ultraviolet Nonlinear Optical Crystal Cs2Al2(B3O6)2O: A Benign Member of the Sr2Be2(BO3)2O Family with [Al2(B3O6)2O]2− Double Layers
by Fang, Zhi and Jiang, Xingxing and Duan, Meihong and Hou, Zhanyu and Tang, Changcheng and Xia, Mingjun and Liu, Lijuan and Lin, Zheshuai and Fan, Feidi and Bai, Lei and Chen, Chuangtian
Chemistry – A European Journal, ISSN 0947-6539, 06/2018, Volume 24, Issue 31, pp. 7856 - 7860
For the explorations of deep ultraviolet (DUV) nonlinear optical (NLO) borates, a type of important optoelectronic material, the (BO3)3− group has been long... 
Cs2Al2(B3O6)2O | deep-ultraviolet | nonlinear optical material | SBBO family | chemical co-substitution | Crystal growth | Optoelectronics | Aluminum | Crystals | Raw materials | Organic chemistry | Energy gap | Beryllium | Birefringence | Cations | Borates | Photonic band gaps | Melts
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4. Full Text Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis
by Sun, Mingming and Wu, Wei and Chen, Liang and Yang, Wenjing and Huang, Xiangsheng and Ma, Caiyun and Chen, Feidi and Xiao, Yi and Zhao, Ye and Ma, Chunyan and Yao, Suxia and Carpio, Victor H and Dann, Sara M and Zhao, Qihong and Liu, Zhanju and Cong, Yingzi
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3555 - 15
T-cells are crucial in maintanence of intestinal homeostasis, however, it is still unclear how microbiota metabolites regulate T-effector cells. Here we show... 
RISK LOCI | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | INTERLEUKIN-10 RECEPTOR | REGULATORY T-CELLS | BUTYRATE ENEMAS | IGA RESPONSE | TRANSCRIPTIONAL REPRESSOR BLIMP-1 | COLONIC-MUCOSA | Up-Regulation | Flagellin - immunology | Gene Expression | Positive Regulatory Domain I-Binding Factor 1 - genetics | Homeostasis | Gene Knockout Techniques | Th1 Cells - immunology | Fatty Acids, Volatile - metabolism | Receptors, G-Protein-Coupled - immunology | TOR Serine-Threonine Kinases - immunology | Fatty Acids, Volatile - immunology | Animals | Mice | Receptors, G-Protein-Coupled - genetics | Gastrointestinal Microbiome - immunology | STAT3 Transcription Factor - immunology | Colitis - immunology | Interleukin-10 - immunology | TOR protein | Antigens | Stat3 protein | Transgenic | Effector cells | Flagellin | Chains | Lymphocytes T | Fatty acids | Inflammatory bowel disease | Proteins | Receptors | Microbiota | Metabolites | Lymphocytes B | Intestine | Interleukin 10 | Colitis
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5. Full Text Microbiome control of innate reactivity
by Chen, Feidi and Stappenbeck, Thaddeus S
Current Opinion in Immunology, ISSN 0952-7915, 02/2019, Volume 56, pp. 107 - 113
Numerous scientific disciplines, including immunology, are now positioned to fully realize the potential of the intestinal microbiome to modulate a wide array... 
TRYPTOPHAN | SUCCINATE-DEHYDROGENASE | COLITIS | ARYL-HYDROCARBON RECEPTOR | CHAIN FATTY-ACIDS | INFLAMMATION | METABOLITE BUTYRATE | GUT | IMMUNOLOGY | CROSSTALK | PROTECTS | Medical colleges | Microbiota (Symbiotic organisms) | Metabolites | Mass spectrometry
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6. Full Text 复合行政视角下国内飞地管理研究
by 陈帅飞 曾伟
湖北理工学院学报：人文社会科学版, ISSN 2095-4662, 2016, Volume 33, Issue 6, pp. 45 - 49
飞地是一种特殊的人文地理现象,其形成有着复杂的历史、经济、行政等方面的原因.文章分析国内飞地的特征和管理现状,指出在转变政府职能的定位并完善飞地管理相关法律的前提下,运用复合行政理念创新飞地管理方式,同时适当调整小规模飞地行政区的区划,是改进我国国内飞地管理的有效途径. 
飞地 | 飞地管理 | 复合行政
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7. Full Text GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3
by Zhao, Ye and Chen, Feidi and Wu, Wei and Sun, Mingming and Bilotta, Anthony J and Yao, Suxia and Xiao, Yi and Huang, Xiangsheng and Eaves-Pyles, Tonyia D and Golovko, George and Fofanov, Yuriy and D'Souza, Warren and Zhao, Qihong and Liu, Zhanju and Cong, Yingzi
Mucosal Immunology, ISSN 1933-0219, 05/2018, Volume 11, Issue 3, pp. 752 - 762
The antimicrobial peptides (AMP) produced by intestinal epithelial cells (IEC) play crucial roles in the regulation of intestinal homeostasis by controlling... 
COMMENSAL BACTERIA | INFLAMMATORY DISEASES | MAINTAIN HOMEOSTASIS | CHAIN FATTY-ACIDS | HOST | BACTERICIDAL LECTIN | GUT MICROBIOTA | PANETH CELLS | DIFFERENTIATION | IMMUNOLOGY | CATHELICIDIN LL-37 | beta-Defensins - genetics | Receptors, G-Protein-Coupled - metabolism | TOR Serine-Threonine Kinases - metabolism | Anti-Infective Agents - metabolism | Mice, Inbred C57BL | Homeostasis | Gastrointestinal Microbiome - physiology | Immunity, Innate | Fatty Acids, Volatile - metabolism | Mice, Knockout | Intestinal Mucosa - physiology | Animals | Mice | Receptors, G-Protein-Coupled - genetics | beta-Defensins - metabolism | Pancreatitis-Associated Proteins - genetics | STAT3 Transcription Factor - metabolism | Pancreatitis-Associated Proteins - metabolism | Microbiota | Index Medicus | RegIIIγ | Defensins | SCFA | GPR43 | IEC
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8. Full Text 1081 - Microbiota Metabolite Short Chain Fatty Acid Acetate Promotes Intestinal IgA Response to Microbiota which is Mediated by GPR43
by Wu, Wei and Sun, Mingming and Chen, Feidi and Yao, Suxia and Liu, Zhanju and Cong, Yingzi
Gastroenterology, ISSN 0016-5085, 04/2017, Volume 152, Issue 5, pp. S199 - S199
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9. Full Text Microbiota Metabolite Short Chain Fatty Acid Acetate Promotes Intestinal IgA Response to Microbiota which is Mediated by GPR43
by Wu, Wei and Sun, Mingming and Chen, Feidi and Yao, Suxia and Liu, Zhanju and Cong, Yingzi
Gastroenterology, ISSN 0016-5085, 2017, Volume 152, Issue 5, pp. S199 - S199
Gastroenterology and Hepatology | Microbiota (Symbiotic organisms) | Metabolites | Immunoglobulin A | Acetates | Fatty acids
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10. Full Text 736 - Microbiota Metabolites Short-Chain Fatty Acids Inhibit TH1 Cell Induction of Colitis Through Promoting IL-10 Production via GPR43
by Sun, Mingming and Wu, Wei and Chen, Feidi and Chen, Liang and Huang, Xiangsheng and Ma, Caiyun and Zhao, Ye and Yao, Suxia and Liu, Zhanju and Cong, Yingzi
Gastroenterology, ISSN 0016-5085, 05/2018, Volume 154, Issue 6, pp. S-153 - S-153
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11. Full Text Unexpected regulatory role of CCR9 in regulatory T cell development
by Evans-Marin, Heather L and Cao, Anthony T and Yao, Suxia and Chen, Feidi and He, Chong and Liu, Han and Wu, Wei and Gonzalez, Maria G and Dann, Sara M and Cong, Yingzi
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0134100
T cells reactive to microbiota regulate the pathogenesis of inflammatory bowel disease (IBD). As T cell trafficking to intestines is regulated through... 
INTESTINAL INFLAMMATION | CXCL12 SDF-1-ALPHA | MUCOSA | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | INFLAMMATORY-BOWEL-DISEASE | STIMULATION | EXPERIMENTAL COLITIS | CROHNS-DISEASE | MULTIDISCIPLINARY SCIENCES | CHEMOKINE RECEPTOR | INDUCTION | Animals | Colitis - physiopathology | Receptors, CCR - genetics | T-Lymphocytes, Regulatory - cytology | Mice, Transgenic | Mice | Receptors, CCR - physiology | Inflammation | Colitis | Dendritic cells | T cells | Gastrointestinal diseases | Inflammatory bowel diseases | Disease | Pathogenesis | Trafficking | Effector cells | Lymphocytes T | Recruitment | Homing | Receptors | Microbiota | Immunology | Lymphocytes | Intestine | Rodents | Gastroenterology | Foxp3 protein | Digestive tract | Immunoglobulins | Immune response | Cytokines | Digestive system | Cell differentiation | Chemokine receptors | Inflammatory bowel disease | Studies | Pathology | Signaling | Immunosuppression | Hospitals | Ligands | Regulation | Internet | CCR9 protein | Chemokines | Cell migration | Cancer
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12. Full Text 7 TLR5 Mediates CD172a+ Intestinal Lamina Propria Dendritic Cell Induction of Th17 Cells
by Liu, Han and Chen, Feidi and Wu, Wei and Evans-Marin, Heather and Li, Yanqing and Cong, Yingzi
Gastroenterology, ISSN 0016-5085, 2016, Volume 150, Issue 4, pp. S2 - S2
Gastroenterology and Hepatology
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13. Full Text 7 TLR5 Mediates CD172a.sup.+ Intestinal Lamina Propria Dendritic Cell Induction of Th17 Cells
by Liu, Han and Chen, Feidi and Wu, Wei and Evans-Marin, Heather and Li, Yanqing and Cong, Yingzi
Gastroenterology, ISSN 0016-5085, 04/2016, Volume 150, Issue 4, p. S2
Dendritic cells
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14. Full Text Effects of Short-Chain Chlorinated Paraffins Exposure on the Viability and Metabolism of Human Hepatoma HepG2 Cells
by Geng, Ningbo and Zhang, Haijun and Zhang, Baoqin and Wu, Ping and Wang, Feidi and Yu, Zhengkun and Chen, Jiping
Environmental Science & Technology, ISSN 0013-936X, 03/2015, Volume 49, Issue 5, pp. 3076 - 3083
Short-chain chlorinated paraffins (SCCPs) have attracted considerable attention for their characteristic of persistent organic pollutants. However, very... 
PATHWAYS | C-10-C-13 | RESPONSES | ENVIRONMENTAL SCIENCES | METABOLOMICS | PLASMA | POLYCHLORO-N-ALKANES | ENGINEERING, ENVIRONMENTAL | LIVER | RATS | TOXICITY | HEALTH | Cell Survival - drug effects | Paraffin - toxicity | Hydrocarbons, Chlorinated - toxicity | Humans | Lipid Metabolism - drug effects | Metabolic Networks and Pathways - drug effects | Hep G2 Cells | Index Medicus
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15. New Insights into the Cytotoxic Mechanism of Hexabromocyclododecane from a Metabolomic Approach
by Feidi Wang and Haijun Zhang and Ningbo Geng and Baoqin Zhang and Xiaoqian Ren and Jiping Chen
Environmental Science & Technology, ISSN 0013-936X, 03/2016, Volume 50, Issue 6, p. 3145
  The toxic effects of hexabromocyclododecane (HBCD) are complex, and the underlying toxicological mechanisms are still not completely understood. In this... 
Oxidative stress | Toxicology | Metabolites | Homeostasis | Cytotoxicity | Organic chemicals
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16. New Insights into the Cytotoxic Mechanism of Hexabromocyclododecane from a Metabolomic Approach
by Wang, Feidi and Zhang, Haijun and Geng, Ningbo and Zhang, Baoqin and Ren, Xiaoqian and Chen, Jiping
Environmental Science & Technology, ISSN 0013-936X, 03/2016, Volume 50, Issue 6, pp. 3145 - 3145
The toxic effects of hexabromocyclododecane (HBCD) are complex, and the underlying toxicological mechanisms are still not completely understood. In this study,... 
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17. Full Text CD177+ neutrophils as functionally activated neutrophils negatively regulate IBD
by Zhou, Guangxi and Yu, Lin and Fang, Leilei and Yang, Wenjing and Yu, Tianming and Miao, Yinglei and Chen, Minhu and Wu, Kaichun and Chen, Feidi and Cong, Yingzi and Liu, Zhanju
Gut, ISSN 0017-5749, 06/2018, Volume 67, Issue 6, pp. 1052 - 1063
BackgroundNeutrophils are accumulated in inflamed mucosa of IBD and play an important role in the pathogenesis. CD177 is expressed in neutrophils specifically... 
INTERLEUKINS | CELLULAR IMMUNOLOGY | MUCOSAL IMMUNOLOGY | IBD BASIC RESEARCH | INTESTINAL INFLAMMATION | BACTERIAL PATHOGENS | INFLAMMATORY-BOWEL-DISEASE | IMMUNE CELLS | EXPERIMENTAL COLITIS | CROHNS-DISEASE | ULCERATIVE-COLITIS | CYTOKINE | GASTROENTEROLOGY & HEPATOLOGY | IL-22 | T-CELLS | Immunohistochemistry | Immunity, Mucosal - immunology | Intestinal Mucosa - metabolism | Humans | Inflammatory Bowel Diseases - immunology | Middle Aged | Male | Inflammatory Bowel Diseases - metabolism | Young Adult | Flow Cytometry | Intestinal Mucosa - immunology | Adult | Female | Cell Culture Techniques | Neutrophils - metabolism | Real-Time Polymerase Chain Reaction | Isoantigens - metabolism | Cytokines - metabolism | Mice, Inbred C57BL | Neutrophils - immunology | Receptors, Cell Surface - metabolism | Mice, Transgenic | GPI-Linked Proteins - metabolism | Animals | Adolescent | Mice
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18. Full Text Commensal A4 bacteria inhibit intestinal Th2-cell responses through induction of dendritic cell TGF-[beta] production
by Wu, Wei and Liu, Hou-Pu and Chen, Feidi and Liu, Han and Cao, Anthony T and Yao, Suxia and Sun, Mingming and Evans-Marin, Heather L and Zhao, Ye and Zhao, Qing and Duck, L. Wayne and Elson, Charles O and Liu, Zhanju and Cong, Yingzi
European Journal of Immunology, ISSN 0014-2980, 05/2016, Volume 46, Issue 5, p. 1162
  It has been shown that while commensal bacteria promote Th1, Th17 and Treg cells in lamina propria (LP) in steady-state conditions, they suppress mucosal Th2... 
Microbiota (Symbiotic organisms) | Dendritic cells | Bone morphogenetic proteins | Bacteria | T cells | Transforming growth factors | Cell differentiation | Rodents
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19. Full Text Developmental and metabolic responses of zebrafish (Danio rerio) embryos and larvae to short-chain chlorinated paraffins (SCCPs) exposure
by Ren, Xiaoqian and Zhang, Haijun and Geng, Ningbo and Xing, Liguo and Zhao, Yu and Wang, Feidi and Chen, Jiping
Science of the Total Environment, ISSN 0048-9697, 05/2018, Volume 622-623, pp. 214 - 221
Short-chain chlorinated paraffins (SCCPs) are highly toxic to aquatic organisms, but their toxicity is yet not well characterized. In this study, the... 
Zebrafish embryo/larvae | Metabolomics | Developmental toxicity | Short-chain chlorinated paraffins | MASS-SPECTROMETRY | N-ALKANES | BIOACCUMULATION | RETINAL GANGLION-CELLS | ENVIRONMENTAL SCIENCES | TROPHIC TRANSFER | BOHAI SEA | LYSOPHOSPHATIDYLCHOLINE | INOSINE | DEREGULATION | PURINE METABOLISM | Physiological aspects | Embryonic development | Unsaturated fatty acids | Amino acids | Index Medicus
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20. Full Text Deep-Ultraviolet Nonlinear Optical Crystal Cs2 Al2 (B3 O6 )2 O: A Benign Member of the Sr2 Be2 (BO3 )2 O Family with [Al2 (B3 O6 )2 O]2− Double Layers
by Fang, Zhi and Jiang, Xingxing and Duan, Meihong and Hou, Zhanyu and Tang, Changcheng and Xia, Mingjun and Liu, Lijuan and Lin, Zheshuai and Fan, Feidi and Bai, Lei and Chen, Chuangtian
Chemistry - A European Journal, ISSN 0947-6539, 06/2018, Volume 24, Issue 31, pp. 7856 - 7860
For the explorations of deep ultraviolet (DUV) nonlinear optical (NLO) borates, a type of important optoelectronic material, the (BO3 )3- group has been long... 
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